Iconicity emerges and is maintained in spoken language

Iconicity is the property whereby signs (vocal or manual) resemble their referents. Iconic signs are easy to relate to the world, facilitating learning and processing. In this study, we examined whether the benefits of iconicity would lead to its emergence and to maintenance in language. We focused on shape iconicity (the association between rounded objects and round-sounding words like “bouba” and between spiky objects and spiky-sounding words like “kiki”) and motion iconicity (the association between longer words and longer events). In Experiment 1, participants generated novel labels for round versus spiky shapes and long versus short movements (Experiment 1a: text, Experiment 1b: speech). Labels for each kind of stimulus differed in a way that was consistent with previous studies of iconicity. This suggests that iconicity emerges even on a completely unconstrainted task. In Experiment 2 (Experiment 2a: text, Experiment 2b: speech), we simulated language change in the laboratory (as iterated learning) and found that both forms of iconicity were introduced and maintained through generations of language users. Thus, we demonstrate the emergence of iconicity in spoken languages, and we argue that these results reflect a pressure for language systems to be referential, which favors iconic forms in the cultural evolution of language (at least up to a point where it is balanced by other pressures, e.g., discriminability). This can explain why we have iconicity across natural languages and may have implications for debates on language origins. (PsycInfo Database Record (c) 2021 APA, all rights reserved

Vitamin Enhanced Waters and Polyphenol Rich Beverages Analyzed for Antioxidant Capacity and Antioxidants/Calorie

The purpose of this study was to analyze polyphenol rich beverages (vitamin enhanced waters (VEWs), fruit juices and berry juices) to determine free polyphenol concentrations and free polyphenols per Calorie based on a serving size. The Folin–Ciocalteu reagent was used in a colorimetric assay based on a catechin standard. Fruit and berry juices contained, on average, more than eight-times the concentration of free polyphenols when compared to VEWs. When Calories per serving were taken into consideration, fruit and berry juices contained more than twice the free polyphenols per Calorie

Presyncope Is Associated with Intensive Care Unit Admission in Emergency Department Patients with Acute Pulmonary Embolism

Introduction: Syncope is common among emergency department (ED) patients with acute pulmonary embolism (PE) and indicates a higher acuity and worse prognosis than in patients without syncope. Whether presyncope carries the same prognostic implications has not been established. We compared incidence of intensive care unit (ICU) admission in three groups of ED PE patients: those with presyncope; syncope; and neither.Methods: This retrospective cohort study included all adults with acute, objectively confirmed PE in 21 community EDs from January 2013–April 2015. We combined electronic health record extraction with manual chart abstraction. We used chi-square test for univariate comparisons and performed multivariate analysis to evaluate associations between presyncope or syncope and ICU admission from the ED, reported as adjusted odds ratios (aOR) with 95% confidence intervals (CI).Results: Among 2996 PE patients, 82 (2.7%) had presyncope and 109 (3.6%) had syncope. ICU admission was similar between groups (presyncope 18.3% vs syncope 25.7%) and different than their non-syncope counterparts (either 22.5% vs neither 4.7%; p<0.0001). On multivariate analysis, both presyncope and syncope were independently associated with ICU admission, controlling for demographics, higher-risk PE Severity Index (PESI) class, ventilatory support, proximal clot location, and submassive and massive PE classification: presyncope, aOR 2.79 (95% CI, 1.40, 5.56); syncope, aOR 4.44 (95% CI 2.52, 7.80). These associations were only minimally affected when excluding massive PE from the model. There was no significant interaction between either syncope or presyncope and PESI, submassive or massive classification in predicting ICU admission.Conclusion: Presyncope appears to carry similar strength of association with ICU admission as syncope in ED patients with acute PE. If this is confirmed, clinicians evaluating patients with acute PE may benefit from including presyncope in their calculus of risk assessment and site-of-care decision-making

Identification and Functional Characterization of Toxoneuron nigriceps Ovarian Proteins Involved in the Early Suppression of Host Immune Response

The endophagous parasitoid Toxoneuron nigriceps (Viereck) (Hymenoptera, Braconidae) of the larval stages of the tobacco budworm Heliothis virescens (Fabricius) (Lepidoptera, Noctuidae) injects the egg, the venom, the calyx fluid, which includes a Polydnavirus (T. nigriceps BracoVirus: TnBV) and the Ovarian Proteins (OPs) into the host body during oviposition. The host metabolism and immune system are disrupted prematurely shortly after parasitization by the combined action of the TnBV, venom, and OPs. OPs are involved in the early suppression of host immune response, before TnBV infects and expresses its genes in the host tissues. In this work, we evaluated the effect of HPLC fractions deriving from in toto OPs. Two fractions caused a reduction in hemocyte viability and were subsequently tested to detect changes in hemocyte morphology and functionality. The two fractions provoked severe oxidative stress and actin cytoskeleton disruption, which might explain the high rate of hemocyte mortality, loss of hemocyte functioning, and hence the host\u2019s reduced hemocyte encapsulation ability. Moreover, through a transcriptome and proteomic approach we identify the proteins of the two fractions: eight proteins were identified that might be involved in the observed host hemocyte changes. Our findings will contribute to a better understanding of the secreted ovarian components and their role in parasitoid wasp strategy for evading host immune responses

Solute Concentrations Influence Microbial Methanogenesis in Coal-bearing Strata of the Cherokee Basin, USA

Microorganisms have contributed significantly to subsurface energy resources by converting organic matter in hydrocarbon reservoirs into methane, the main component of natural gas. In this study, we consider environmental controls on microbial populations in coal-bearing strata of the Cherokee basin, an unconventional natural gas resource in southeast Kansas, USA. Pennsylvanian-age strata in the basin contain numerous thin (0.4-1.1 m) coalbeds with marginal thermal maturities (0.5-0.7% Ro) that are interbedded with shale and sandstone. We collected gas, water, and microbe samples from 16 commercial coalbed methane wells for geochemical and microbiological analysis. The water samples were Na-Cl type with total dissolved solids (TDS) content ranging from 34.9 to 91.3 g L?1. Gas dryness values [C1/(C2 + C3)] averaged 2640 and carbon and hydrogen isotope ratios of methane differed from those of carbon dioxide and water, respectively, by an average of 65 and 183%. These values are thought to be consistent with gas that formed primarily by hydrogenotrophic methanogenesis. Results from cultivation assays and taxonomic analysis of 16S rRNA genes agree with the geochemical results. Cultivable methanogens were present in every sample tested, methanogen sequences dominate the archaeal community in each sample (avg 91%), and few archaeal sequences (avg 4.2%) were classified within Methanosarcinales, an order of methanogens known to contain methylotrophic methanogens. Although hydrogenotrophs appear dominant, geochemical and microbial analyses both indicate that the proportion of methane generated by acetoclastic methanogens increases with the solute content of formation water, a trend that is contrary to existing conceptual models. Consistent with this trend, beta diversity analyses show that archaeal diversity significantly correlates with formation water solute content. In contrast, bacterial diversity more strongly correlates with location than solute content, possibly as a result of spatial variation in the thermal maturity of the coalbeds.Citation: Kirk MF, Wilson BH, Marquart KA, Zeglin LH, Vinson DS and Flynn TM (2015) Solute Concentrations Influence Microbial Methanogenesis in Coal-bearing Strata of the Cherokee Basin, USA. Front. Microbiol. 6:1287. doi: 10.3389/fmicb.2015.0128

Lifetime determination of excited states in Cd-106

Two separate experiments using the Differential Decay Curve Method have been performed to extract mean lifetimes of excited states in 106 Cd. The inedium-spin states of interest were populated by the Mo-98(C-12, 4n) Cd-106 reaction performed at the Wright Nuclear Structure Lab., Yale University. From this experiment, two isomeric state mean lifetimes have been deduced. The low-lying states were populated by the Mo-96(C-13, 3n)Cd-106 reaction performed at the Institut fur Kernphysik, Universitat zu Koln. The mean lifetime of the I-pi = 2(1)(+) state was deduced, tentatively, as 16.4(9) ps. This value differs from the previously accepted literature value from Coulomb excitation of 10.43(9) ps

Self-medication with oral antibiotics among University students in United Arab Emirates

Purpose: To investigate the prevalence of antibiotic use without prescriptions and to identify factors associated with this behavior among university students using oral non-prescription drugs (ONPD). Methods: A cross-sectional study was conducted among the students of major universities in UAE. A multistage sampling technique was used in the present study. Results: Out of 2875 students, only 2355 (81.9 %) questionnaire were fully answered and included. Of 2355, more than half (1348; 57.2 %) of the participants reported using ONPD. More than one-third (484, 35.9 %) of 1348 participants used antibiotics without a prescription during the 90 days prior to the present study. Binary logistic regression identified nine statistically significant variables: nationality (OR = 0.471, 95 % CI: 0.326 - 0.681, p < 0.001); cost-influence behavior (OR = 1.716, 95 % CI: 1.175 - 2.508, p < 0.005); belief in ONPD effectiveness (OR = 0.332, 95 % CI: 0 .135 - 0.815, p < 0.05); year of study (OR = 0.310, 95 %, CI: 0.141 - 0.681, p < 0.004); medication knowledge (OR = 0.619, 95 % CI: 0.443 - 0.866, p < 0.005); self-care orientation (OR=1.878, 95 % CI: 1.304 - 2.706, p < 0.001); using ONPD helps to save money (OR=1.665, 95 % CI: 1.047-2.649, p<0.04); and urgency of use (OR = 1.644, 95 %, CI: 1.144 - 2.363, p < 0.007); as well as being healthcare students (OR = 1.465, 95 %, CI: 1.012 - 2.120, p < 0.05). Conclusion: There is a need for educational intervention to improve students’ knowledge, attitude, and awareness regarding the risk of using antibiotics without prescriptions