520 research outputs found
Pengaruh Penambahan Serat Ijuk dan Kawat Bendrat pada Paving Block
Paving block merupakan salah satu alternatif pengganti perkerasan rigid yang ada. Khususnya di daerah yang mempunyai kekuatan struktur tanah labil. Pada penelitian ini mencoba untuk memberikan keragaman komposisi dengan menambahkan ijuk dan kawat bendrat, mengingat paving block yang ada hanya terdiri komponen struktur semen dan pasir. Komposisi penambahan ijuk bernilai 2%, 4%, 6% dan 8% terhadap berat semen yang di tuangkan ke dalam 2/3 cetakan paving block, dan penambahan kawat bendrat 1, 2 dan 3 gulungan yang diletakkan pada 1/3 ketinggian paving block. Komposisi campuran semen dan pasir 1 : 11. Penambahan kawat ijuk sebesar 6% dengan 2 gulung kawat bendrat menghasilkan kekuatan maksimal sebesar 2,325 MPa atau selisih 501,65% dari paving block normal
Isolation site influences virulence phenotype of serotype 14 Streptococcus pneumoniae strains belonging to multilocus sequence type 15
Streptococcus pneumoniae is a diverse species causing invasive as well as localized infections that result in massive global morbidity and mortality. Strains vary markedly in pathogenic potential, but the molecular basis is obscured by the diversity and plasticity of the pneumococcal genome. We have previously reported that S. pneumoniae serotype 3 isolates belonging to the same multilocus sequence type (MLST) differed markedly in in vitro and in vivo phenotypes, in accordance with the clinical site of isolation, suggesting stable niche adaptation within a clonal lineage. In the present study, we have extended our analysis to serotype 14 clinical isolates from cases of sepsis or otitis media that belong to the same MLST (ST15). In a murine intranasal challenge model, five ST15 isolates (three from blood and two from ears) colonized the nasopharynx to similar extents. However, blood and ear isolates exhibited significant differences in bacterial loads in other host niches (lungs, ear, and brain) at both 24 and 72 h postchallenge. In spite of these differences, blood and ear isolates were present in the lungs at similar levels at 6 h postchallenge, suggesting that early immune responses may underpin the distinct virulence phenotypes. Transcriptional analysis of lung tissue from mice infected for 6 h with blood isolates versus ear isolates revealed 8 differentially expressed genes. Two of these were exclusively expressed in response to infection with the ear isolate. These results suggest a link between the differential capacities to elicit early innate immune responses and the distinct virulence phenotypes of clonally related S. pneumoniae strains
An Investigation into the Connection between Language Proficiency and Text Analysis Abilities in English Learners
This study’s objective is to evaluate whether or not there is a correlation between students’ command of the English language and their analytical prowess with regard to written material. Through quantitative and qualitative study on students with varied degrees of linguistic proficiency, it has been found that an increase in one’s level of linguistic competence is strongly and favorably associated with an increase in one’s ability for textual analysis. This discovery was made on students with varying levels of linguistic proficiency. Learners who have a higher degree of language competency are able to more effectively absorb vocabulary, grammatical structure, and logical links in the discourse when reading and interpreting English texts. This is because they have a better understanding of the English language. As a consequence of this, they are capable of performing text analysis in a manner that is both more effective and more accurate than before. This article’s goal is to give instructional strategies for learners of all language levels in order to optimize the process of strengthening those learners’ ability to evaluate texts. The target audience for this article is learners of all language levels. When these strategies are utilized, educators will be provided with practical recommendations that will assist them in more effectively directing students toward mastery of the basic text analysis skills. The outcomes of this study may, in some way, have an impact on the educational practice of teaching English as a second language
Assessment of near infrared LED radiation pattern using Otsu thresholding
This paper describes the use of Otsu thresholding method in assessing the radiation pattern emitted by near infrared (NIR) LED. The NIR LED configured in this paper is intended to be used as illumination source for the development of a NIR palm vein image acquisition device. The experiment is conducted using a single board computer (SBC) to promote a real-time embedded system development that can be readily integrated as a vein viewing device. Based on the Otsu thresholded image obtained, it is observed that the NIR LED radiation pattern can be accessed subjectively through the thresholding process. The resulted thresholded image can be used as preliminary assessment of the radiation pattern in developing a NIR image acquisition system that fully utilizes the NIR LED properties
Seroprevalence and detection of contagious bovine pleuropneumonia (CBPP) in northeast states of Peninsular Malaysia
Contagious Bovine Pleuropneumonia (CBPP) is a highly infectious disease of cattle caused by Mycoplasma mycoides subsp. mycoides Small Colony (MmmSC). It is a disease recognised by OIE that needs to be controlled or eradicated through surveillance system. This study establishes the sero-prevalence of CBPP, as well as attempts to isolate and identify the agent of CBPP from cattle in Kelantan and Terengganu, the northeastern states of Peninsular Malaysia, where cattle movement was high. A total of 3,242 sera from 428 farms were processed between 2011 and 2014 using the competitive ELISA (c-ELISA). The animal-level prevalence ranged between 5% (46/917) in Terengganu and 9% (220/2325) in Kelantan, whereas the herd prevalence ranged between 12% (22/210) in Terengganu and 24% (53/218) in Kelantan. The overall animal-level prevalence was 8% (266/3242), while the herd prevalence was 17% (75/428). Two hundred and four nasal swabs from 18 positive herds in Kelantan and 163 lung and mediastinal lymph node samples were processed for isolation of MmmSc before confirmation by PCR and immunoperoxidase. Forty-one samples showed turbidity in PPLO broth and 15 lung and mediastinal lymph node samples had 'fried-egg colony' growth on the PPLO agar, which were suggestive of Mycoplasma infection. However, all were negative for MmmSC by PCR and immunoperoxidase. Thus, the northeastern part of Peninsular Malaysia remains positive serology for CBPP without isolation
Squamous cell carcinoma of the tongue in a patient with rothmund-thomson syndrome (Recq4 Mutation) - intolerance to radiotherapy
We report a case of squamous cell carcinoma of the base of the tongue in a 27 years old patient with Rothmund-Thomson syndrome (RTS). An abnormal DNA repair mechanism in some RTS patients predispose them to malignancy and influence the tolerance to radiotherapy
Cardiovascular Pharmacogenomics and Cognitive Function in Patients with Schizophrenia
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138379/1/phar1968_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138379/2/phar1968.pd
The potential of SiC Cascode JFETs in electric vehicle traction inverters
The benefits of implementing SiC devices in EV powertrains has been widely reported in various studies. New generations of SiC devices including planar MOSFETs, trench MOSFETs and more recently, cascode JFETs have been released by various manufacturers. SiC cascode devices comprise of low voltage silicon MOSFETs for gate driving and high voltage depletion mode SiC JFETs for voltage blocking. These devices are particularly interesting because it avoids the known reliability issues of SiC gate oxide traps resulting in threshold voltage drift. In this paper, an EV powertrain is simulated using experimental measurements of conduction and switching energies of various SiC devices including 650V trench, 900V planar and 650V cascode JFETs. Unlike previous papers where losses are calculated using models based on datasheet parameters, here static and dynamic measurements on the power devices at different currents and temperatures are used to calculate losses over simulated driving cycles. Field-stop IGBTs are also evaluated. The 3-phase 2-level inverter model is electrothermal by accounting for the measured temperature dependence of the losses and uses accurate thermal networks derived from datasheets. Converter efficiency and thermal performance are compared for each device technology. Results show that SiC cascode JFETs have great potential in EV powertrain applications
Fast switching SiC cascode JFETs for EV traction inverters
This paper investigates the potential performance of high speed SiC cascode JFETs in EV traction inverters with high switching frequencies. Traction inverters implemented with SiC devices have shown improved energy conversion efficiency compared to IGBT based traction inverters however SiC MOSFETs suffer from unstable threshold voltage due to charge trapping at the SiC/SiO 2 (due to high density of traps). Since SiC cascode JFETs combine low voltage silicon MOSFETs (at the input) with high speed/high-power density SiC JFETs (at the output), cascode JFETs combine the electrical gate oxide reliability of silicon devices with the power density of SiC. This paper simulates an EV driving cycle using experimental power loss measurements (at different currents and temperatures) of commercially available 650V SiC cascode JFETs and SiC MOSFETs. The inverter has been simulated at 10, 25 and 50 kHz to investigate the impact of increased switching frequency on device losses. The model is fully electrothermal since conduction and switching losses have been measured at different junction temperatures and used as inputs to the model. The results show the potential of superior performance of the SiC cascode JFET in terms of power loss and junction temperature swings. Furthermore, since higher switching frequencies might be desirable in future high-speed traction motors, the fast switching and low loss performance of SiC Cascode JFETs becomes more attractive
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