Slow relaxation to equipartition in spring-chain systems

In this study, one-dimensional systems of masses connected by springs, i.e., spring-chain systems, are investigated numerically. The average kinetic energy of chain-end particles of these systems is larger than that of other particles, which is similar to the behavior observed for systems made of masses connected by rigid links. The energetic motion of the end particles is, however, transient, and the system relaxes to thermal equilibrium after a while, where the average kinetic energy of each particle is the same, that is, equipartition of energy is achieved. This is in contrast to the case of systems made of masses connected by rigid links, where the energetic motion of the end particles is observed in equilibrium. The timescale of relaxation estimated by simulation increases rapidly with increasing spring constant. The timescale is also estimated using the Boltzmann-Jeans theory and is found to be in quite good agreement with that obtained by the simulation

THE RELATIONSHIP BETWEEN STRIDE MECHANICS AND SHOULDER DISTRACTION FORCE IN COLLEGIATE SOFTBALL PITCHERS

The purpose of this study was to determine the relationship between stride mechanics and shoulder distraction force in softball pitchers. Sixty-three collegiate softball pitchers (age: 20.1 ± 1.3 yrs, height: 173.3 ± 7.4 cm, weight: 79.7 ± 11.7 kg) participated and threw three maximal effort fastballs for a strike. Kinematic data were collected using an electromagnetic tracking system with a sampling frequency of 100 Hz. Regression analysis revealed a significant positive relationship between stride length and shoulder distraction force [R2 = .11; F (1, 61) = 7.345, p = .009], where stride length accounted for 11% of the variation in shoulder distraction force. Specifically, shoulder distraction force increased by .94 N/kg for every 10% increase in stride length normalized as a percentage of body height

Design of Easily Synchronizable Oscillator Networks Using the Monte Carlo Optimization Method

Starting with an initial random network of oscillators with a heterogeneous frequency distribution, its autonomous synchronization ability can be largely improved by appropriately rewiring the links between the elements. Ensembles of synchronization-optimized networks with different connectivities are generated and their statistical properties are studied

Lidocaine for systemic sclerosis: a double-blind randomized clinical trial

Background: Systemic sclerosis (scleroderma; SSc) is an orphan disease with the highest case-specific mortality of any connective-tissue disease. Excessive collagen deposit in affected tissues is a key for the disease's pathogenesis and comprises most of the clinical manifestations. Lidocaine seems to be an alternative treatment for scleroderma considering that: a) the patient's having excessive collagen deposits in tissues affected by scleroderma; b) the patient's demonstrating increased activity of the enzyme prolyl hydroxylase, an essential enzyme for the biosynthesis of collagen; and c) lidocaine's reducing the activity of prolyl hydroxylase. the aim of this study was to evaluate the efficacy and safety of lidocaine in treating scleroderma.Methods: A randomized double-blind clinical trial included 24 patients with scleroderma randomized to receive lidocaine or placebo intravenously in three cycles of ten days each, with a one-month interval between them. Outcomes: cutaneous (modified Rodnan skin score), oesophageal (manometry) and microvascular improvement (nailfold capillaroscopy); improvement in subjective self-assessment and in quality of life (HAQ).Results: There was no statistically significant difference between the groups for any outcome after the treatment and after 6-months follow-up. Improvement in modified Rodnan skin score occurred in 66.7% and 50% of placebo and lidocaine group, respectively (p = 0.408). Both groups showed an improvement in subjective self-assessment, with no difference between them.Conclusions: Despite the findings of a previous cohort study favouring the use of lidocaine, this study demonstrated that lidocaine at this dosage and means of administration showed a lack of efficacy for treating scleroderma despite the absence of significant adverse effects. However, further similar clinical trials are needed to evaluate the efficacy of lidocaine when administered in different dosages and by other means.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Brazilian Cochrane Ctr, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Discipline Emergency Med & Evidence Based Med, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Discipline Rheumatol, São Paulo, BrazilUniv Santo Amaro, Discipline Rheumatol, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Brazilian Cochrane Ctr, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Discipline Emergency Med & Evidence Based Med, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Discipline Rheumatol, São Paulo, BrazilFAPESP: 01-13895-9Web of Scienc

Observations of the supernova remnant W28 at TeV energies

The atmospheric Cerenkov imaging technique has been used to search for point-like and diffuse TeV gamma-ray emission from the southern supernova remnant, W28, and surrounding region. The search, made with the CANGAROO 3.8m telescope, encompasses a number of interesting features, the supernova remnant itself, the EGRET source 3EG J1800-2338, the pulsar PSR J1801-23, strong 1720 MHz OH masers and molecular clouds on the north and east boundaries of the remnant. An analysis tailored to extended and off-axis point sources was used, and no evidence for TeV gamma-ray emission from any of the features described above was found in data taken over the 1994 and 1995 seasons. Our upper limit (E>1.5 TeV) for a diffuse source of radius 0.25deg encompassing both molecular clouds was calculated at 6.64e-12 photons cm^-2 s^-1 (from 1994 data), and interpreted within the framework of a model predicting TeV gamma-rays from shocked-accelerated hadrons. Our upper limit suggests the need for some cutoff in the parent spectrum of accelerated hadrons and/or slightly steeper parent spectra than that used here (-2.1). As to the nature of 3EG J1800-2338, it possibly does not result entirely from pi-zero decay, a conclusion also consistent with its location in relation to W28.Comment: 11 pages, 5 figures. Accepted for publication in Astronomy and Astrophysic

Size Segregation and Convection of Granular Mixtures Almost Completely Packed in the Rotating Thin Box

Size segregation of granular mixtures which are almost completely packed in a rotating drum is discussed with an effective simulation and a brief analysis. Instead of a 3D drum, we simulate 2D rotating thin box which is almost completely packed with granular mixtures. The phase inversion of radially segregated pattern which was found in a 3D experiment are qualitatively reproduced with this simulation, and a brief analysis is followed. Moreover in our simulation, a global convection appears after radial segregation pattern is formed, and this convection induces axially segregated pattern.Comment: 9 pages, 5 figures, PACS number(s): 45.70.-n, 45.70.M

Evidence for TeV gamma-ray emission from the shell type SNR RXJ1713.7-3946

We report the results of TeV gamma-ray observations of the shell type SNR RXJ1713.7-3946 (G347.3-0.5). The discovery of strong non-thermal X-ray emission from the northwest part of the remnant strongly suggests the existence of electrons with energies up to 100 TeV in the remnant, making the SNR a good candidate TeV gamma-ray source. We observed RXJ1713.7-3946 from May to August 1998 with the CANGAROO 3.8m atmospheric imaging Cerenkov telescope and obtained evidence for TeV gamma-ray emission from the NW rim of the remnant with the significance of 5.6 sigma. The observed TeV gamma-ray flux from the NW rim region was estimated to be (5.3 +/- 0.9[statistical] +/- 1.6[systematic]) * 10^{-12} photons cm^{-2} s^{-1} at energies >= 1.8 +/- 0.9 TeV. The data indicate that the emitting region is much broader than the point spread function of our telescope. The extent of the emission is consistent with that of hard X-rays observed by ASCA. This TeV gamma-ray emission can be attributed to the Inverse Compton scattering of the Cosmic Microwave Background Radiation by shock accelerated ultra-relativistic electrons. Under this assumption, a rather low magnetic field of 11 micro gauss is deduced for the remnant from our observation.Comment: Accepted for publication by Astronomy and Astrophysics (5 pages, 2 figures