59 research outputs found
Competition-based model of pheromone component ratio detection in the moth
For some moth species, especially those closely interrelated and sympatric, recognizing a specific pheromone component concentration ratio is essential for males to successfully locate conspecific females. We propose and determine the properties of a minimalist competition-based feed-forward neuronal model capable of detecting a certain ratio of pheromone components independently of overall concentration. This model represents an elementary recognition unit for the ratio of binary mixtures which we propose is entirely contained in the macroglomerular complex (MGC) of the male moth. A set of such units, along with projection neurons (PNs), can provide the input to higher brain centres. We found that (1) accuracy is mainly achieved by maintaining a certain ratio of connection strengths between olfactory receptor neurons (ORN) and local neurons (LN), much less by properties of the interconnections between the competing LNs proper. An exception to this rule is that it is beneficial if connections between generalist LNs (i.e. excited by either pheromone component) and specialist LNs (i.e. excited by one component only) have the same strength as the reciprocal specialist to generalist connections. (2) successful ratio recognition is achieved using latency-to-first-spike in the LN populations which, in contrast to expectations with a population rate code, leads to a broadening of responses for higher overall concentrations consistent with experimental observations. (3) when longer durations of the competition between LNs were observed it did not lead to higher recognition accuracy
Crises and collective socio-economic phenomena: simple models and challenges
Financial and economic history is strewn with bubbles and crashes, booms and
busts, crises and upheavals of all sorts. Understanding the origin of these
events is arguably one of the most important problems in economic theory. In
this paper, we review recent efforts to include heterogeneities and
interactions in models of decision. We argue that the Random Field Ising model
(RFIM) indeed provides a unifying framework to account for many collective
socio-economic phenomena that lead to sudden ruptures and crises. We discuss
different models that can capture potentially destabilising self-referential
feedback loops, induced either by herding, i.e. reference to peers, or
trending, i.e. reference to the past, and account for some of the phenomenology
missing in the standard models. We discuss some empirically testable
predictions of these models, for example robust signatures of RFIM-like herding
effects, or the logarithmic decay of spatial correlations of voting patterns.
One of the most striking result, inspired by statistical physics methods, is
that Adam Smith's invisible hand can badly fail at solving simple coordination
problems. We also insist on the issue of time-scales, that can be extremely
long in some cases, and prevent socially optimal equilibria to be reached. As a
theoretical challenge, the study of so-called "detailed-balance" violating
decision rules is needed to decide whether conclusions based on current models
(that all assume detailed-balance) are indeed robust and generic.Comment: Review paper accepted for a special issue of J Stat Phys; several
minor improvements along reviewers' comment
Diurnal and Circadian Rhythms in the Tomato Transcriptome and Their Modulation by Cryptochrome Photoreceptors
BACKGROUND: Circadian clocks are internal molecular time-keeping mechanisms that provide living organisms with the ability to adjust their growth and physiology and to anticipate diurnal environmental changes. Circadian clocks, without exception, respond to light and, in plants, light is the most potent and best characterized entraining stimulus. The capacity of plants to respond to light is achieved through a number of photo-perceptive proteins including cryptochromes and phytochromes. There is considerable experimental evidence demonstrating the roles of photoreceptors in providing light input to the clock. METHODOLOGY: In order to identify genes regulated by diurnal and circadian rhythms, and to establish possible functional relations between photoreceptors and the circadian clock in tomato, we monitored the temporal transcription pattern in plants entrained to long-day conditions, either by large scale comparative profiling, or using a focused approach over a number of photosensory and clock-related genes by QRT-PCR. In parallel, focused transcription analyses were performed in cry1a- and in CRY2-OX tomato genotypes. CONCLUSIONS: We report a large series of transcript oscillations that shed light on the complex network of interactions among tomato photoreceptors and clock-related genes. Alteration of cryptochrome gene expression induced major changes in the rhythmic oscillations of several other gene transcripts. In particular, over-expression of CRY2 had an impact not only on day/night fluctuations but also on rhythmicity under constant light conditions. Evidence was found for widespread diurnal oscillations of transcripts encoding specific enzyme classes (e.g. carotenoid biosynthesis enzymes) as well as for post-transcriptional diurnal and circadian regulation of the CRY2 transcript
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ĐбŃĐ”ĐșŃĐŸĐŒ ĐžŃŃĐ»Đ”ĐŽĐŸĐČĐ°ĐœĐžŃ ĐżĐŸĐŽŃĐžŃŃĐ”ĐŒĐ° ĐșĐŸŃŃĐŸĐ·ĐžĐŸĐœĐœĐŸĐłĐŸ ĐŒĐŸĐœĐžŃĐŸŃĐžĐœĐłĐ° ŃлДĐșŃŃĐŸŃ
ĐžĐŒĐžŃĐ”ŃĐșĐŸĐč Đ·Đ°ŃĐžŃŃ ĐŒĐ°ĐłĐžŃŃŃĐ°Đ»ŃĐœĐŸĐłĐŸ ĐłĐ°Đ·ĐŸĐżŃĐŸĐČĐŸĐŽĐ°. ĐŠĐ”Đ»Ń ŃĐ°Đ±ĐŸŃŃ â ĐżŃĐŸĐ°ĐœĐ°Đ»ĐžĐ·ĐžŃĐŸĐČĐ°ŃŃ ŃĐżŃĐ°ĐČĐ»Đ”ĐœĐžĐ” ŃĐžŃŃĐ”ĐŒĐŸĐč ŃлДĐșŃŃĐŸŃ
ĐžĐŒĐžŃĐ”ŃĐșĐŸĐč Đ·Đ°ŃĐžŃŃ ĐŒĐ°ĐłĐžŃŃŃĐ°Đ»ŃĐœĐŸĐłĐŸ ĐłĐ°Đ·ĐŸĐżŃĐŸĐČĐŸĐŽĐ° ĐČ ŃŃĐ»ĐŸĐČĐžŃŃ
ĐČĐ”ŃĐœĐŸĐč ĐŒĐ”ŃĐ·Đ»ĐŸŃŃ. Đ ŃДзŃĐ»ŃŃĐ°ŃĐ” Đ°ĐœĐ°Đ»ĐžĐ·Đ° ŃŃŃĐ°ĐœĐŸĐČĐ»Đ”ĐœĐŸ, ŃŃĐŸ ĐĐĐ-йХй-ĐĐŸĐœŃĐĐŸŃŃ ŃĐŽĐŸĐČлДŃĐČĐŸŃŃĐ”Ń ŃŃĐ”Đ±ĐŸĐČĐ°ĐœĐžŃĐŒ ŃĐžŃŃĐ”ĐŒŃ ŃĐżŃĐ°ĐČĐ»Đ”ĐœĐžŃ ŃĐ”Ń
ĐœĐžŃĐ”ŃĐșĐžĐŒ ŃĐŸŃŃĐŸŃĐœĐžĐ”ĐŒ Đž ŃĐ”Đ»ĐŸŃŃĐœĐŸŃŃŃŃ ĐżĐ»ĐŸŃĐ°ĐŽĐœŃŃ
ĐŸĐ±ŃĐ”ĐșŃĐŸĐČ ĐŸŃĐłĐ°ĐœĐžĐ·Đ°ŃОО.The object of study is the subsystem of corrosion monitoring of electrochemical protection of the main gas pipeline. The purpose of the work is to analyze the management of the system of electrochemical protection of the main gas pipeline in permafrost conditions. As a result of the analysis, it was established that PKM-TST-KontKorr satisfies the requirements of the system for managing the technical condition and integrity of the organizationâs area facilities
Measurement of Z0 decays to hadrons, and a precise determination of the number of neutrino species
We have made a precise measurement of the cross section for e+e--->Z0-->hadrons with the L3 detector at LEP, covering the range from 88.28 to 95.04 GeV. From a fit to the Z0 mass, total width, and the hadronic cross section to be MZ0=91.160 +/- 0.024 (experiment) +/-0.030(LEP) GeV, [Gamma]Z0=2.539+/-0.054 GeV, and [sigma]h(MZ0)=29.5+/-0.7 nb. We also used the fit to the Z0 peak cross section and the width todetermine [Gamma]invisible=0.548+/-0.029 GeV, which corresponds to 3.29+/-0.17 species of light neutrinos. The possibility of four or more neutrino flavors is thus ruled out at the 4[sigma] confidence level.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28683/3/0000500.pd
A measurement of the Z0 leptonic partial widths and the vector and axial vector coupling constants
We have measured the partial widths of the Z0 into lepton pairs, and the forward-backward charge asymmetry for the process e+e--->[mu]+[mu]- using the L3 detector at LEP. We obtain an average [Gamma]ll of 83.0+/-2.1+/-1.1 MeV.From this result and the asymmetry measurement, we extract the values of the vector and axial vector couplings of the Z0 to leptons: grmv=-0.066-0.027+0.046 and grmA= -0.495-0.007+0.007.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28666/3/0000483.pd
Interaction of phenol and dopamine with commercial MWCNTs
We report the adsorption of phenol and dopamine probe molecules, from aqueous solution with NaCl, on commercial multiwall carbon nanotubes (MWCNT) and on their carboxylated derivative. The nanotubes were fully characterized by high resolution transmission electron microscopy (HRTEM), small angle X-ray scattering (SAXS), potentiometric titration, electrophoretic mobility, and nitrogen adsorption (77K) measurements. The experimental pollutant isotherms, evaluated using the Langmuir model, showed that only 8-12% and 21-32% of the BET surface area was available for phenol and dopamine, respectively, which is far below the performance of activated carbons. Influence of the pH was more pronounced for the oxidized MWCNT, particularly with dopamine. The strongest interaction and the highest adsorption capacity occurred at pH 3 with both model pollutants on both types of nanotubes. Although the surface area available for adsorption is far lower in MWCNTs than in activated carbons, it is nonetheless substantial. In particular, delayed release of toxic molecules that are either adsorbed on the surface or trapped in the inner bore of such systems could constitute an environmental hazard. The need for further adsorption studies with regard to their environmental aspects is therefore pressing, particularly for MWCNTs in their functionalized state
Novel neuronal and astrocytic mechanisms in thalamocortical loop dynamics.
In this review, we summarize three sets of findings that have recently been observed in thalamic astrocytes and neurons, and discuss their significance for thalamocortical loop dynamics. (i) A physiologically relevant 'window' component of the low-voltage-activated, T-type Ca(2+) current (I(Twindow)) plays an essential part in the slow (less than 1 Hz) sleep oscillation in adult thalamocortical (TC) neurons, indicating that the expression of this fundamental sleep rhythm in these neurons is not a simple reflection of cortical network activity. It is also likely that I(Twindow) underlies one of the cellular mechanisms enabling TC neurons to produce burst firing in response to novel sensory stimuli. (ii) Both electrophysiological and dye-injection experiments support the existence of gap junction-mediated coupling among young and adult TC neurons. This finding indicates that electrical coupling-mediated synchronization might be implicated in the high and low frequency oscillatory activities expressed by this type of thalamic neuron. (iii) Spontaneous intracellular Ca(2+) ([Ca(2+)](i)) waves propagating among thalamic astrocytes are able to elicit large and long-lasting N-methyl-D-aspartate-mediated currents in TC neurons. The peculiar developmental profile within the first two postnatal weeks of these astrocytic [Ca(2+)](i) transients and the selective activation of these glutamate receptors point to a role for this astrocyte-to-neuron signalling mechanism in the topographic wiring of the thalamocortical loop. As some of these novel cellular and intracellular properties are not restricted to thalamic astrocytes and neurons, their significance may well apply to (patho)physiological functions of glial and neuronal elements in other brain areas
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