375 research outputs found
On IT risk management ontology using DEMO
Nowadays, organisations use and rely on Information Technology (IT) solutions. However, despite their benefits, IT solutions induct risks. Consequently, organisations implement Risk Management (RM), more specifically Information Technology Risk Management (IT RM), in order to maximize the effectiveness of IT usage while dealing with IT risks. Nevertheless, IT RM's implementation is not easy, since numerous standards and frameworks propose multiple RM processes to deal with IT risks. Moreover, these processes are composed of different activities causing confusion. In the end, organisations are not capable of managing risks successfully due to IT RM's complexity. To overcome IT RM diversity, a Systematic Literature Review (SLR) was conducted. The goal is to identify which are the most essential IT RM activities. The SLR results were then integrated with ISO 31000 and PMBOK standards in the form of an ontology using Design and Engineering Methodology Ontology (DEMO). The contributions of this study are: the aggregate analysis of IT RM activities through the SLR; the identification of reasons and benefits of using DEMO; a description of an IT RM's essential model designed as an ontology; and a critical view of the benefits of the ontological model proposed.info:eu-repo/semantics/acceptedVersio
Adolescents who stay, parents who migrate: gender inequalities, resilience and coping strategies in Tajikistan
Studies on the consequences of migration often ignore the
perspectives of children and adolescents who remain in the origin
country while their migrant parents are absent. This is the case in
Tajikistan, one of the poorest and most remittance-dependent
countries in the world. Using a qualitative methodology, microethnography, we interviewed eight teenagers aged between 12 and
18, in the city of Khorugh, Tajikistan, to explore the impact of
migration from their perspective. Findings reveal that these
adolescents âunderstandâ the reasons for their parentsâ migration in a
way that both gives coherence to this migration and invests young
people with resilience and coping strategies. As a result, all the
young people naturalised having to live with sadness, reflecting the
ânormalisationâ of this social cost in wider Tajik society. However, the
experiences and coping strategies of those interviewed are
gendered; boys were more likely to ârationaliseâ their experience and
be aloof; girls more likely to express emotional upset. In practical
terms, boys also received more benefits from remittances while girls
reported feeling overwhelmed by domestic chores expected of
them. Through this study, we contribute to the recent literature on
the lived experiences and agency of non-migrant teenagers.info:eu-repo/semantics/acceptedVersio
An exploratory study on teamsâ performance, client-reported outcomes and satisfaction
Background: Community pharmacy teams (CPTs) have an established role in assisting self-medication, contributing to the safe and effective use of non-prescription medicines. Objective: The study aimed to describe CPTsâ performance in self-medication consultation, client-reported outcomes, and satisfaction. A secondary purpose was to develop an explanatory model for better understanding clientsâ satisfaction with this service. Methods: Descriptive, cross-sectional exploratory study. Data were collected in a purposive sample of pharmacy clients recruited in six community pharmacies in Portugal. CPTs adopted a structured approach to self-medication consultations, encompassing 11 quality criteria (five for case evaluation and six for counselling). An evaluation score, a counselling score and an overall quality score were estimated. Client-reported outcomes and satisfaction were ascertained via a follow-up telephone interview. Besides descriptive statistics, the association with several independent variables on the clientsâ overall satisfaction was explored, using linear regression. Results: Product-based dispensing was more frequent for lower educated clients. Reported compliance with the criteria by CPTs was overall high (93.95% of maximum compliance), mostly missing the âother medicationâ questioning. Most clients (93%) reported improvement after the consultation. Clientsâ satisfaction score was 4.70 out of 5. The variables that seem to better explain clientsâ overall satisfaction are pharmacy loyalty, the evaluation score, and the female gender. Conclusions: Clientsâ reported outcomes were favourable, as well as satisfaction with the service. Clientsâ satisfaction appears to be determined by consultation quality (evaluation score), suggesting the advancement of the pharmacistsâ clinical role. A larger study is warranted to confirm these findings.publishersversionpublishe
Dichotic listening and spect in dyslexic children
Dichotic listening (DL) was evaluated in 36 children with: verbal dichotic listening test, alternating dissilable dichotic test and non-verbal dichotic listening test. Children were separated into two groups: experimental group with 18 dyslexic children and control group with 18 normal children. Both groups were comparable in gender, laterality and social-economic level. All dyslexic children underwent neuroimaging exam (SPECT). Our data showed that there was a statistical difference between both groups in all DL tests. Abnormal SPECT findings were seen in 50% of the dyslexic children, hypoperfusion of the left temporal lobe being the most frequent abnormality. We conclude that dyslexic children present an impairment of central neurologic processing that may be detected by DL tests, and by functional imaging exam, such as SPECT, as well.Aplicamos em um grupo de 36 crianças os testes dicĂłtico de dĂgitos, dicĂłtico de dissĂlabos alternados e dicĂłtico nĂŁo-verbal, os quais fazem parte do conjunto de avaliação do processamento auditivo. As crianças foram divididas em dois grupos que foram correlacionados: grupo experimental (GE) formado por 18 crianças com diagnĂłstico de dislexia e 18 crianças normais compondo o grupo comparação (GC), sem queixa de aprendizagem e pareadas em relação a sexo, lateralidade e nĂvel sĂłcio-econĂŽmico ao GE. Realizamos o exame de imagem (SPECT) no GE. Encontramos em nosso estudo diferença estatisticamente significante entre os grupos (GE e GC) em todos os testes avaliados. Em relação ao SPECT, apesar de nĂŁo encontrarmos diferença estatisticamente significante entre os resultados, pudemos observar que 50% dos sujeitos avaliados apresentaram alteração, sendo a maior parte em ĂĄreas do lobo temporal esquerdo. ConcluĂmos que crianças com dislexia apresentam alteraçÔes do processamento neurolĂłgico central que podem ser detectadas tanto em testes especĂficos de processamento auditivo, quanto em exames funcionais de imagem como SPECT.Universidade Estadual de SĂŁo Paulo Faculdade de CiĂȘncias MĂ©dicas Departamento de NeurologiaUniversidade Federal de SĂŁo Paulo (UNIFESP) Departamento de DistĂșrbios da ComunicaçãoUNIFESP, Depto. de DistĂșrbios da ComunicaçãoSciEL
Lower solar atmosphere and magnetism at ultra-high spatial resolution
We present the scientific case for a future space-based telescope aimed at
very high spatial and temporal resolution imaging of the solar photosphere and
chromosphere. Previous missions (e.g., HINODE, SUNRISE) have demonstrated the
power of observing the solar photosphere and chromosphere at high spatial
resolution without contamination from Earth's atmosphere. We argue here that
increased spatial resolution (from currently 70 km to 25 km in the future) and
high temporal cadence of the observations will vastly improve our understanding
of the physical processes controlling solar magnetism and its characteristic
scales. This is particularly important as the Sun's magnetic field drives solar
activity and can significantly influence the Sun-Earth system. At the same time
a better knowledge of solar magnetism can greatly improve our understanding of
other astrophysical objects
Reprodução assexuada de carobinha em função do tipo de estaca e uso de fito-hormÎnio.
O objetivo desta pesquisa foi verificar o surgimento de folhas e/ou raĂzes em função do tipo de estaca e solução de fito-hormĂŽnio na planta medicinal carobinha (Jacaranda decurrens). O experimento teve 4 tratamentos e 8 repetiçÔes totalizando 32 parcelas
Diretrizes técnicas para a exploração de impacto reduzido em operaçÔes florestais de Terra Firme na AmazÎnia Brasileira.
Apresentação geral das diretrizes técnicas. Diretrizes para as atividades pré-exploratórias. diretrizes para as atividades de exploração florestal. Diretrizes para as atividades pós-exploratórias.bitstream/item/63188/1/Oriental-Doc64.pd
Yarrowia lipolytica as a cell factory to produce valuable compounds
Book of Abstracts of CEB Annual Meeting 2017Yarrowia lipolytica, a strictly aerobic yeast, with GRAS status, has an intense secretory activity and can
metabolize a wide range of substrates that guaranteed a spot as an interesting industrial organism.
Recently, food supplements derived from this yeast were approved for commercialization, which is
particularly important for broadening the range of possible applications of the compounds produced by
Y. lipolytica [1]. Within âBioprocess Development and Optimizationâ research team, Y. lipolytica has been
used as a cell model and exploited applying the biorefinery concept for the production of enzymes,
microbial lipids, aroma and organic acids, using low-cost renewable substrates.
A yeast-based integrated system was developed to valorize agro-industrial wastes, namely waste
cooking oils and lard (used as a model of animal fat), by producing microbial lipids and lipase. The yeast
oil content accumulated by Y. lipolytica from these inexpensive wastes was one of the higher ever
reported for a non-genetically modified Yarrowia strain. Moreover, the simultaneous production of
lipase may reduce the production cost of the microbial lipids and demonstrates that a biorefinery
approach may be designed based on fat raw materials, allowing at the same time the reduction of fatty
wastes surplus.
Lipids accumulation on Y. lipolytica may also occur from non-oily substrates such as glucose or glycerol
that can also lead to citric acid (CA) production under nitrogen-limitation conditions. Crude glycerol, byproduct
from Biodiesel industry, has been used for CA production. Optimization of CA has been carried
out by enhancing oxygen transfer rate at different types of bioreactors, such as STR, pressurized and
airlift, as well as by mutagenesis strategies for strains improvement.
Yarrowia lipolytica is a model microorganism for lipids metabolism. It can produce several compounds
from fatty acids catabolism, mainly aromatic compounds, such as lactones. This species is able to
transform ricinoleic acid into Îł-decalactone, a peach-like aroma compound of great importance for
flavoring industry. The production of Îł-decalactone has been intensively studied in order to better
understand all process and optimize it. The role of lipases in substrate hydrolysis, the effect of substrate
concentration, dissolved oxygen concentration and different fermentation strategies - batch and stepwise
fed-batch â and bioreactor designs (STR and airlift) in the Îł-decalactone production was
investigated [2]. The characterization of Îł-decalactone production by genetic modified strains at labscale
bioreactor was also performed. Yarrowia lipolytica potential to produce other aromatic
compounds, such as 2-phenylethanol, is been now explored.info:eu-repo/semantics/publishedVersio
Dichotic listening and SPECT in dyslexic children
Dichotic listening (DL) was evaluated in 36 children with: verbal dichotic listening test, alternating dissilable dichotic test and non-verbal dichotic listening test. Children were separated into two groups: experimental group with 18 dyslexic children and control group with 18 normal children. Both groups were comparable in gender, laterality and social-economic level. All dyslexic children underwent neuroimaging exam (SPECT). Our data showed that there was a statistical difference between both groups in all DL tests. Abnormal SPECT findings were seen in 50% of the dyslexic children, hypoperfusion of the left temporal lobe being the most frequent abnormality. We conclude that dyslexic children present an impairment of central neurologic processing that may be detected by DL tests, and by functional imaging exam, such as SPECT, as well.64110811
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