Solutions for Neutral for Axi-Dilaton Gravity in 4-Dimensions

We examine a 1 parameter class of actions describing the gravitational interaction between a pair of scalar fields and Einsteinian gravitation. When the parameter is positive the theory corresponds to an axi-dilatonic sector of low energy string theory. We exploit an SL(2,R) symmetry of the theory to construct a family of electromagnetically neutral solutions with non-zero axion and dilaton charge from solutions of the Brans-Dicke theory. We also comment on solutions to the theory with negative coupling parameter.Comment: 7 pages Plain Tex (No Figures), Letter to Editor, Classical and Quantum Gravit

Effect of different irrigation water level on cotton yield and yield components

Effects of different water level on yield and yield components of the drip irrigated cotton were evaluated in Amik Plain in the East Mediterranean Region of Turkey. Four levels of irrigation water were tested in2003 and 2004. Treatments were 25 (I25), 50 (I50), 75% (I75) of the full irrigation treatment (I100) which received 100% class-A pan evaporation. Numbers of irrigation events were 5 and 8 in 2003 and 2004, respectively. Under I25, I50 and I75 treatment conditions, evapotranspiration, total cotton seed yield, boll weight, lint percentage, number of sympodial branches and leaf area index decreased while some boll parameters such as boll weights and opened boll numbers increased. Increase of boll number per plant under water stress condition showed that cotton had high ability for adapting water stress conditions. The highest yield was obtained in the I100 treatment. A second degree polynomial relation could adequately describe the cotton seed yield response to the irrigation water amount. The highestirrigation water use efficiency (IWUE) was obtained with the I50 treatment

Minimum Common Outage Probability for the Broadcast Relay Channel

In this paper the broadcast relay channel (BRC) is studied. In the BRC model, the source communicates with two destinations with the help of a single relay. The minimum common outage probability for four different transmission protocols, direct transmission (DT), multihop (MH), path selection (PS) and link combination with path selection (LCPS) is investigated under long-term power constraint for constant rate transmission. In addition, the epsilon-outage rate region for a fixed common outage probability is computed. Based on the cut-set bound (CSB), a lower bound on the minimum common outage probability and an upper bound on the epsilon-outage rate region are also found. Numerical results suggest that enforcing the relay to help both destinations simultaneously is limiting. The dominant factor in the gains obtained with respect to DT is due to path selection and link combination is not necessary when the relay is close to the source

Extreme Peripheral Blood Plasmacytosis Mimicking Plasma Cell Leukemia as a Presenting Feature of Angioimmunoblastic T-Cell Lymphoma (AITL).

Angioimmunoblastic T-cell lymphoma (AITL) is one of four major subtypes of nodal peripheral T cell lymphoma, characterized by its cell of origin, the follicular helper T-cell (TFH). Patients typically present with prominent constitutional (B) symptoms, generalized lymphadenopathy, hepatosplenomegaly, cytopenias, and rash. Here we present a case of a 62-year-old male with progressive cervical adenopathy, fevers and weight loss presenting with extreme polyclonal plasmacytosis and high plasma EBV viral load. While the initial presentation appeared to mimic plasma cell leukemia or severe infection, lymph node biopsy and bone marrow biopsy confirmed a diagnosis of AITL. This case highlights the heterogeneity of the clinical presentation of AITL to enable physicians to more promptly recognize, diagnose and initiate treatment

Effects of factors on direct screw withdrawal resistance in medium density fiberboard and particleboard

An increase in demand on solid wood that is insufficient supply to meet in the world necessarily directed to other engineering materials that could be an alternative to the solid wood. In this context, instead of using solid wood in furniture and construction industry, wood-based panels such as medium density fiberboard (MDF) and particleboard (PB) have become widely used as construction material. Limited research has been done in the field of fastener performance as mechanical properties with different parameters in the joints constructed with these panels. Therefore, in this study, the parameters of screw type, pilot hole, screw orientation, water treatment and adhesives were investigated in MDF and PB. The results indicated that the highest direct screw withdrawal (DSW) resistance was observed in the test blocks applied with PU and the lowest DSW resistance was in the test blocks without a pilot hole drilled in both materials. In addition, MDF in general had better DSW resistance than PB in almost all combinations of the parameters. The treatment of water into MDF and PB test blocks negatively affects the DSW resistance. The DSW resistance in the face orientation was found to be higher than the corresponding ones in the side orientation in both materials

Geriatric pharmacotherapy : optimisation through integrated approach in the hospital setting

Since older patients are more vulnerable to adverse drug-related events, there is a need to ensure appropriate prescribing in these patients in order to prevent misuse, overuse and underuse of drugs. Different tools and strategies have been developed to reduce inappropriate prescribing; the available measures can be divided into medication assessment tools, and specific interventions to reduce inappropriate prescribing. Implicit criteria of inappropriate prescribing focus on appropriate dosing, search for drug-drug interactions, and increase adherence. Explicit criteria are consensus-based standards focusing on drugs and diseases and include lists of drugs to avoid in general or lists combining drugs with clinical data. These criteria take into consideration differences between patients, and stand for a medication review, by using a systematic approach. Different types of interventions exist in order to reduce inappropriate prescribing in older patients, such as: educational interventions, computerized decision support systems, pharmacist-based interventions, and geriatric assessment. The effects of these interventions have been studied, sometimes in a multifaceted approach combining different techniques, and all types seem to have positive effects on appropriateness of prescribing. Interdisciplinary teamwork within the integrative pharmaceutical care is important for improving of outcomes and safety of drug therapy. The pharmaceutical care process consists offour steps, which are cyclic for an individual patient. These steps are pharmaceutical anamnesis, medication review, design and follow-up of a pharmaceutical care plan. A standardized approach is necessary for the adequate detection and evaluation of drug-related problems. Furthermore, it is clear that drug therapy should be reviewed in-depth, by having full access to medical records, laboratory values and nursing notes. Although clinical pharmacists perform the pharmaceutical care process to manage the patient’s drug therapy in every day clinical practice, the physician takes the ultimate responsibility for the care of the patient in close collaboration with nurses

New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity.

Interleukin-15 (IL-15) is a potent cytokine that increases CD8+ T and NK cell numbers and function in experimental models. However, obstacles remain in using IL-15 therapeutically, specifically its low potency and short in vivo half-life. To help overcome this, a new IL-15 superagonist complex comprised of an IL-15N72D mutation and IL-15RαSu/Fc fusion (IL-15SA, also known as ALT-803) was developed. IL-15SA exhibits a significantly longer serum half-life and increased in vivo activity against various tumors. Herein, we evaluated the effects of IL-15SA in recipients of allogeneic hematopoietic stem cell transplantation. Weekly administration of IL-15SA to transplant recipients significantly increased the number of CD8+ T cells (specifically CD44+ memory/activated phenotype) and NK cells. Intracellular IFN-γ and TNF-α secretion by CD8+ T cells increased in the IL-15SA-treated group. IL-15SA also upregulated NKG2D expression on CD8+ T cells. Moreover, IL-15SA enhanced proliferation and cytokine secretion of adoptively transferred CFSE-labeled T cells in syngeneic and allogeneic models by specifically stimulating the slowly proliferative and nonproliferative cells into actively proliferating cells.We then evaluated IL-15SA\u27s effects on anti-tumor activity against murine mastocytoma (P815) and murine B cell lymphoma (A20). IL-15SA enhanced graft-versus-tumor (GVT) activity in these tumors following T cell infusion. Interestingly, IL-15 SA administration provided GVT activity against A20 lymphoma cells in the murine donor leukocyte infusion (DLI) model without increasing graft versus host disease. In conclusion, IL-15SA could be a highly potent T- cell lymphoid growth factor and novel immunotherapeutic agent to complement stem cell transplantation and adoptive immunotherapy