1,701 research outputs found

    Solutions for Neutral for Axi-Dilaton Gravity in 4-Dimensions

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    We examine a 1 parameter class of actions describing the gravitational interaction between a pair of scalar fields and Einsteinian gravitation. When the parameter is positive the theory corresponds to an axi-dilatonic sector of low energy string theory. We exploit an SL(2,R) symmetry of the theory to construct a family of electromagnetically neutral solutions with non-zero axion and dilaton charge from solutions of the Brans-Dicke theory. We also comment on solutions to the theory with negative coupling parameter.Comment: 7 pages Plain Tex (No Figures), Letter to Editor, Classical and Quantum Gravit

    Effect of different irrigation water level on cotton yield and yield components

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    Effects of different water level on yield and yield components of the drip irrigated cotton were evaluated in Amik Plain in the East Mediterranean Region of Turkey. Four levels of irrigation water were tested in2003 and 2004. Treatments were 25 (I25), 50 (I50), 75% (I75) of the full irrigation treatment (I100) which received 100% class-A pan evaporation. Numbers of irrigation events were 5 and 8 in 2003 and 2004, respectively. Under I25, I50 and I75 treatment conditions, evapotranspiration, total cotton seed yield, boll weight, lint percentage, number of sympodial branches and leaf area index decreased while some boll parameters such as boll weights and opened boll numbers increased. Increase of boll number per plant under water stress condition showed that cotton had high ability for adapting water stress conditions. The highest yield was obtained in the I100 treatment. A second degree polynomial relation could adequately describe the cotton seed yield response to the irrigation water amount. The highestirrigation water use efficiency (IWUE) was obtained with the I50 treatment

    Minimum Common Outage Probability for the Broadcast Relay Channel

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    In this paper the broadcast relay channel (BRC) is studied. In the BRC model, the source communicates with two destinations with the help of a single relay. The minimum common outage probability for four different transmission protocols, direct transmission (DT), multihop (MH), path selection (PS) and link combination with path selection (LCPS) is investigated under long-term power constraint for constant rate transmission. In addition, the epsilon-outage rate region for a fixed common outage probability is computed. Based on the cut-set bound (CSB), a lower bound on the minimum common outage probability and an upper bound on the epsilon-outage rate region are also found. Numerical results suggest that enforcing the relay to help both destinations simultaneously is limiting. The dominant factor in the gains obtained with respect to DT is due to path selection and link combination is not necessary when the relay is close to the source

    Extreme Peripheral Blood Plasmacytosis Mimicking Plasma Cell Leukemia as a Presenting Feature of Angioimmunoblastic T-Cell Lymphoma (AITL).

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    Angioimmunoblastic T-cell lymphoma (AITL) is one of four major subtypes of nodal peripheral T cell lymphoma, characterized by its cell of origin, the follicular helper T-cell (TFH). Patients typically present with prominent constitutional (B) symptoms, generalized lymphadenopathy, hepatosplenomegaly, cytopenias, and rash. Here we present a case of a 62-year-old male with progressive cervical adenopathy, fevers and weight loss presenting with extreme polyclonal plasmacytosis and high plasma EBV viral load. While the initial presentation appeared to mimic plasma cell leukemia or severe infection, lymph node biopsy and bone marrow biopsy confirmed a diagnosis of AITL. This case highlights the heterogeneity of the clinical presentation of AITL to enable physicians to more promptly recognize, diagnose and initiate treatment

    Effects of factors on direct screw withdrawal resistance in medium density fiberboard and particleboard

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    An increase in demand on solid wood that is insufficient supply to meet in the world necessarily directed to other engineering materials that could be an alternative to the solid wood. In this context, instead of using solid wood in furniture and construction industry, wood-based panels such as medium density fiberboard (MDF) and particleboard (PB) have become widely used as construction material. Limited research has been done in the field of fastener performance as mechanical properties with different parameters in the joints constructed with these panels. Therefore, in this study, the parameters of screw type, pilot hole, screw orientation, water treatment and adhesives were investigated in MDF and PB. The results indicated that the highest direct screw withdrawal (DSW) resistance was observed in the test blocks applied with PU and the lowest DSW resistance was in the test blocks without a pilot hole drilled in both materials. In addition, MDF in general had better DSW resistance than PB in almost all combinations of the parameters. The treatment of water into MDF and PB test blocks negatively affects the DSW resistance. The DSW resistance in the face orientation was found to be higher than the corresponding ones in the side orientation in both materials

    Geriatric pharmacotherapy : optimisation through integrated approach in the hospital setting

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    Since older patients are more vulnerable to adverse drug-related events, there is a need to ensure appropriate prescribing in these patients in order to prevent misuse, overuse and underuse of drugs. Different tools and strategies have been developed to reduce inappropriate prescribing; the available measures can be divided into medication assessment tools, and specific interventions to reduce inappropriate prescribing. Implicit criteria of inappropriate prescribing focus on appropriate dosing, search for drug-drug interactions, and increase adherence. Explicit criteria are consensus-based standards focusing on drugs and diseases and include lists of drugs to avoid in general or lists combining drugs with clinical data. These criteria take into consideration differences between patients, and stand for a medication review, by using a systematic approach. Different types of interventions exist in order to reduce inappropriate prescribing in older patients, such as: educational interventions, computerized decision support systems, pharmacist-based interventions, and geriatric assessment. The effects of these interventions have been studied, sometimes in a multifaceted approach combining different techniques, and all types seem to have positive effects on appropriateness of prescribing. Interdisciplinary teamwork within the integrative pharmaceutical care is important for improving of outcomes and safety of drug therapy. The pharmaceutical care process consists offour steps, which are cyclic for an individual patient. These steps are pharmaceutical anamnesis, medication review, design and follow-up of a pharmaceutical care plan. A standardized approach is necessary for the adequate detection and evaluation of drug-related problems. Furthermore, it is clear that drug therapy should be reviewed in-depth, by having full access to medical records, laboratory values and nursing notes. Although clinical pharmacists perform the pharmaceutical care process to manage the patient’s drug therapy in every day clinical practice, the physician takes the ultimate responsibility for the care of the patient in close collaboration with nurses

    Synthesis of Novel 6-(4-Substituted piperazine-1-yl)-9(b-D-ribofuranosyl) purine Derivatives, Which Lead to Senescence-Induced Cell Death in liver Cancer Cells

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    Cataloged from PDF version of article.Novel purine ribonucleoside analogues (9-13) containing a 4-substituted piperazine in the substituent at N-6 were synthesized and evaluated for their cytotoxicity on Huh7, HepG2, FOCUS, Mahlavu liver, MCF7 breast, and HCT116 colon carcinoma cell lines. The purine nucleoside analogues were analyzed initially by an anticancer drug-screening method based on a sulforhodamine B assay. Two nucleoside derivatives with promising cytotoxic activities (11 and 12) were further analyzed on the hepatoma cells. The N-6-(4-Trifluoromethylphenyl)piperazine analogue 11 displayed the best antitumor activity, with IC50 values between 5.2 and 9.2 mu M. Similar to previously described nucleoside analogues, compound 11 also interferes with cellular ATP reserves, possibly through influencing cellular kinase activities. Furthermore, the novel nucleoside analogue 11 was shown to induce senescence-associated cell death, as demonstrated by the SA beta-gal assay. The senescence-dependent cytotoxic effect of 11 was also confirmed through phosphorylation of the Rb protein by p15(INK4b) overexpression in the presence of this compound
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