Why implusive behaviour may be good for your health

__Abstract__ Just as we can give in to our oh-so guilty impulses in moments of weakness, new research shows that under the right circumstances these impulses can in fact lead us to engage in behaviour that is actually more conducive to our health

POLITICAL ELECTIONS FOR MARKETERS

SrFe12O19 coatings, intended as electromagnetic wave absorbers, were produced by atmospheric plasma spraying (APS) using two different kindsof feedstock powders: spray-dried agglomerates of micrometric SrFe12O19 particles (type-A) or spray-dried agglomerates of raw materials (SrCO3,Fe2O3), reactively sintered at 1100 ◦C (type-B).During spraying, type-A agglomerates either remain unmelted, producing porous coating regions where crystalline hexaferrite is retained, orare disrupted into smaller granules which melt completely, resulting in dense coating regions with no crystalline hexaferrite.The sintered type-B agglomerates possess higher cohesive strength and do not fall apart: the finer ones melt completely, whereas, in the largerones, the outer region melts and infiltrates the porous unmelted core which retains crystalline hexaferrite. Dense coatings can therefore be obtainedwhile preserving high amounts of crystalline hexaferrite even inside the dense areas. Such coatings show magnetic properties that are promisingfor electromagnetic wave absorption applications

Estimation of Wear Resistance in Acid Solution of Dental Ceramics by Neural Network

It is known that exposure to acid causes damage to the glass surface. The aim of this study was to examine wear resistance, measuring the mass change of dental ceramics after contact with 10-3 mol dm-3 HCl at temperature of 50°C. Four samples of dental ceramics were analyzed: feldspatic ceramic, hydrothermal ceramic, glass ceramic for staining and glass ceramic for layering. The mass concentrations of eluted Na+, K+ and Ca2+ were determined by ion chromatography (IC) and mass concentrations of Si4+ and Al3+ by UV/VIS spectrometry. Measurements were conducted after 1, 2, 3, 6 and 12 months of emersion. For the subject issue, using experimental data, the feedforward backpropagation neural network for estimation of wear resistance of dental ceramics was modelled. The results of 1, 2 and 12 months of emersion were used for the training 13-20-5 model of neural network. Comparison of experimental data and data obtained by estimation (results of 3 and 6 month intervals) of neural network shows that the applied network model provided a very good prediction of wear behavior of dental ceramics with high correlation coefficient (R) and low sum of squared error (SSE) between measurement and estimated output values

The Effect of Micro-oxygenation on the Phenolic Composition, Quality and Aerobic Wine-Spoilage Microorganisms of Different South African Red Wines

The effect of micro-oxygenation treatments on the composition of different South African red wines was evaluated.  In some wines, micro-oxygenation led to an increase in colour density, with a corresponding change in colour, due to the formation of polymeric pigments. This increase also led to the red colour becoming more resistant to the bleaching effect of SO2. Micro-oxygenation also seemed to be more effective in increasing the colour densities of younger red wines than the older ones, although total red pigments were found to be highest in an older red wine that had received micro-oxygenation. Differences in the gelatine index were also observed over time. The micro-oxygenated and barrel-matured wines also had lower concentrations of catechin and the procyanidin B1, and showed a corresponding increase in polymeric pigment and polymeric phenols. Micro-oxygenation led to higher acetic acid bacteria counts, although no increase in volatile acidity was observed in these wines. A tasting panel preferredyounger red wines that had undergone micro-oxygenation. In an older red wine prolonged micro-oxygenation led to the wine becoming over-aged, with an increase in the barnyard/medicinal character, which corresponded with an increase in Brettanomyces counts. Micro-oxygenation can be used to increase the quality of young red wines, but further research is needed in this area

3D Voronoi Tessellation for the Study of Mechanical Behavior of Rocks at Different Scales

Numerical investigation of crack damage development and microfracturing in brittle rocks is a widely studied topic, given the number of applications involved. In the framework of the Discrete Element Method (DEM) formulation, the grain-based distinct element model with random polygonal blocks can represent an alternative to the Bonded-Particle Model (BPM) based on particles. Recently, a new engine called Neper has been made available for generating 3D Voronoi grains. The aim of this study is to investigate the applicability of a Neper-based 3D Voronoi tessellation technique for the simulation of the mechanical macro response of rocks. Simulation of unconfined compression tests on synthetic specimens is conducted and a calibration procedure tested. The issue related to scale effects is also addressed, with an application to the case study of a deep geothermal reservoir

The influence of polydispersity on the structural properties of the isotropic phase of magnetic nanoplatelets

By employing a combination of Molecular Dynamics simulations and experimental SAXS studies, we investigate low-concentration suspensions of polydisperse magnetic platelets with dipole moments perpendicular to the platelets' plane. Exploiting the precise control of platelet size and shape in simulation, we are also able to contrast these results with equivalent density monodisperse suspensions. We show how the polydispersity may lead to the reduction of the orientational and spatial correlations in the absence of an applied field, while simultaneously facilitating the field-induced transition into a nematic-like phase. Along with structural properties, we investigate the magnetic response. This allows us to confirm that the inter-platelet magnetic correlations have a negligible influence on the structure of the low-density suspensions. © 2020Austrian Science Fund, FWF: START-Projekt A Y 627-N27OeAD-GmbH, OEAD: SI 13/2016Russian Science Foundation, RSF: 19-12-00209Javna Agencija za Raziskovalno Dejavnost RS, ARRS: J7-8267, P2-0089, P1-0192American Roentgen Ray Society, ARRS: BI-AT/18-19-009This research has been supported by the Russian Science Foundation Grant 19-12-00209 . The work was also supported by the FWF START-Projekt A Y 627-N27 . Simulations were performed in Vienna Scientific Cluster (VSC3 and VSC4). NS, DL, ŽG and AM acknowledge the financial support from the Slovenian Research Agency (research core funding P1-0192 and P2-0089 and the project J7-8267 ). Also, the financial support from OeAD and the Slovenian Research Agency for a bilateral project (WTZ grant number SI 13/2016 and ARRS grant number BI-AT/18-19-009 ) is acknowledged. We acknowledge support by Prof. H. Peterlik and the Faculty center for Nano Structure Research at the University of Vienna for the assistance with the SAXS measurements and for the use of Bruker AXS Nanostar. We also thank Ekaterina Novak for assistance with the calculation of bond order parameters

Бокс в Томском Политехническом университете

Это первая книга о боксе в одном из томских университетов. События, факты, рассказы о боксёрах и их тренерах основаны на документальных материалах, в том числе из архивных источников, воспоминаниях ветеранов и действующих спортсменов. Это знак благодарности и признания боксёрам, тренерам и спортивным организаторам за их нелёгкую, но благодарную работу, за популяризацию бокса. В результате работы получилась содержательная и увлекательная книга, которая вызовет несомненный интерес у читателей, и будет способствовать популяризации такого замечательного вида единоборств как бокс

Complementary hydro-mechanical coupled finite/discrete element and microseismic modelling to predict hydraulic fracture propagation in tight shale reservoirs

This paper presents a novel approach to predict the propagation of hydraulic fractures in tight shale reservoirs. Many hydraulic fracture modelling schemes assume that the fracture direction is pre-seeded in the problem domain discretization. This is a severe limitation as the reservoir often contains large numbers of pre-existing fractures that strongly influence the direction of the propagating fracture. To circumvent these shortcomings a new fracture modelling treatment is proposed where the introduction of discrete fracture surfaces is based on new and dynamically updated geometrical entities rather than the topology of the underlying spatial discretization. Hydraulic fracturing is an inherently coupled engineering problem with interactions between fluid flow and fracturing when the stress state of the reservoir rock attains a failure criterion. This work follows a staggered hydro-mechanical coupled finite/discrete element approach to capture the key interplay between fluid pressure and fracture growth. In field practice the fracture growth is hidden from the design engineer and microseismicity is often used to infer hydraulic fracture lengths and directions. Microsesimic output can also be computed from changes of the effective stress in the geomechanical model and compared against field microseismicity. A number of hydraulic fracture numerical examples are presented to illustrate the new technology

Impact of Leaf Removal, Applied Before and After Flowering, on Anthocyanin, Tannin, and Methoxypyrazine Concentrations in ‘Merlot’ (Vitis viniferaL.) Grapes and Wines

7siThe development and accumulation of secondary metabolites in grapes determine wine color, taste, and aroma. This study aimed to investigate the effect of leaf removal before flowering, a practice recently introduced to reduce cluster compactness and Botrytis rot, on anthocyanin, tannin, and methoxypyrazine concentrations in Merlot' grapes and wines. Leaf removal before flowering was compared with leaf removal after flowering and an untreated control. No effects on tannin and anthocyanin concentrations in grapes were observed. Both treatments reduced levels of 3-isobutyl-2-methoxypyrazine (IBMP) in the grapes and the derived wines, although the after-flowering treatment did so to a greater degree in the fruit specifically. Leaf removal before flowering can be used to reduce cluster compactness, Botrytis rot, and grape and wine IBMP concentration and to improve wine color intensity but at the expense of cluster weight and vine yield. Leaf removal after flowering accomplishes essentially the same results without loss of yield. © 2016 American Chemical Society.reservedmixedSivilotti, Paolo; Herrera, Jose Carlos; Lisjak, Klemen; Baša Česnik, Helena; Sabbatini, Paolo; Peterlunger, Enrico; Castellarin, Simone DiegoSivilotti, Paolo; Herrera, Jose Carlos; Lisjak, Klemen; Baša Česnik, Helena; Sabbatini, Paolo; Peterlunger, Enrico; Castellarin, Simone Dieg

Coumarin derivatives act as novel inhibitors of human dipeptidyl peptidase III: combined in vitro and in silico study

Dipeptidyl peptidase III (DPP III), a zinc- dependent exopeptidase, is a member of the metalloproteinase family M49 with distribution detected in almost all forms of life. Although the physiological role of human DPP III (hDPP III) is not yet fully elucidated, its involvement in pathophysiological processes such as mammalian pain modulation, blood pressure regulation, and cancer processes, underscores the need to find new hDPP III inhibitors. In this research, five series of structurally different coumarin derivatives were studied to provide a relationship between their inhibitory profile toward hDPP III combining an in vitro assay with an in silico molecular modeling study. The experimental results showed that 26 of the 40 tested compounds exhibited hDPP III inhibitory activity at a concentration of 10 µM. Compound 12 (3-benzoyl-7-hydroxy-2H-chromen-2-one) proved to be the most potent inhibitor with IC50 value of 1.10 μM. QSAR modeling indicates that the presence of larger substituents with double and triple bonds and aromatic hydroxyl groups on coumarin derivatives increases their inhibitory activity. Docking predicts that 12 binds to the region of inter-domain cleft of hDPP III while binding mode analysis obtained by MD simulations revealed the importance of 7- OH group on the coumarin core as well as enzyme residues Ile315, Ser317, Glu329, Phe381, Pro387, and Ile390 for the mechanism of the binding pattern and compound 12 stabilization. The present investigation, for the first time, provides an insight into the inhibitory effect of coumarin derivatives on this human metalloproteinase