Domain structure in CoFeB thin films with perpendicular magnetic anisotropy

Domain structures in CoFeB-MgO thin films with a perpendicular easy magnetization axis were observed by magneto-optic Kerr-effect microscopy at various temperatures. The domain wall surface energy was obtained by analyzing the spatial period of the stripe domains and fitting established domain models to the period. In combination with SQUID measurements of magnetization and anisotropy energy, this leads to an estimate of the exchange stiffness and domain wall width in these films. These parameters are essential for determining whether domain walls will form in patterned structures and devices made of such materials

Self-trapped bidirectional waveguides in a saturable photorefractive medium

We introduce a time-dependent model for the generation of joint solitary waveguides by counter-propagating light beams in a photorefractive crystal. Depending on initial conditions, beams form stable steady-state structures or display periodic and irregular temporal dynamics. The steady-state solutions are non-uniform in the direction of propagation and represent a general class of self-trapped waveguides, including counterpropagating spatial vector solitons as a particular case.Comment: 4 pages, 5 figure

The Effects And Efficiency Of Hearing Stories On Vocabulary Acquisition By Students Of German AS A Second Foreign Language In Japan

The usual approach to vocabulary learning is to present students with a list of words to be memorized, present them in the context of a text, and then provide exercises to “reinforce” the vocabulary. The purpose of these studies with beginning level German-as-a-foreign language university students in Japan was to determine whether beginning level students with limited vocabulary in German could sustain their interest in hearing a story for over 20 minutes, and to determine how much vocabulary could be gained just from hearing stories, without a list to memorize and supplementary vocabulary exercises. The first experiment showed that hearing a story had a higher acquisition/learning rate than a list method. The second and third experiments showed that supplementary focus on form activities were not worthwhile on vocabulary acquisition/learning, and that the rate of acquisition/learning was .10 words per minute during the seven weeks. It appears to be the case that students acquire six words per hour when they hear stories, while they learn 2.4 words per hour in traditional classes

A rare presentation of atypical demyelination: tumefactive multiple sclerosis causing Gerstmann's syndrome

r. KS has been supported by a Higher Education Funding Council for England (HEFCE) Clinical Senior Lectureshi

Genomic resources for Myzus persicae: EST sequencing, SNP identification, and microarray design

<p>Abstract</p> <p>Background</p> <p>The green peach aphid, <it>Myzus persicae </it>(Sulzer), is a world-wide insect pest capable of infesting more than 40 plant families, including many crop species. However, despite the significant damage inflicted by <it>M. persicae </it>in agricultural systems through direct feeding damage and by its ability to transmit plant viruses, limited genomic information is available for this species.</p> <p>Results</p> <p>Sequencing of 16 <it>M. persicae </it>cDNA libraries generated 26,669 expressed sequence tags (ESTs). Aphids for library construction were raised on <it>Arabidopsis thaliana</it>, <it>Nicotiana benthamiana</it>, <it>Brassica oleracea, B. napus</it>, and <it>Physalis floridana </it>(with and without <it>Potato leafroll virus </it>infection). The <it>M. persicae </it>cDNA libraries include ones made from sexual and asexual whole aphids, guts, heads, and salivary glands. <it>In silico </it>comparison of cDNA libraries identified aphid genes with tissue-specific expression patterns, and gene expression that is induced by feeding on <it>Nicotiana benthamiana</it>. Furthermore, 2423 genes that are novel to science and potentially aphid-specific were identified. Comparison of cDNA data from three aphid lineages identified single nucleotide polymorphisms that can be used as genetic markers and, in some cases, may represent functional differences in the protein products. In particular, non-conservative amino acid substitutions in a highly expressed gut protease may be of adaptive significance for <it>M. persicae </it>feeding on different host plants. The Agilent eArray platform was used to design an <it>M. persicae </it>oligonucleotide microarray representing over 10,000 unique genes.</p> <p>Conclusion</p> <p>New genomic resources have been developed for <it>M. persicae</it>, an agriculturally important insect pest. These include previously unknown sequence data, a collection of expressed genes, molecular markers, and a DNA microarray that can be used to study aphid gene expression. These resources will help elucidate the adaptations that allow <it>M. persicae </it>to develop compatible interactions with its host plants, complementing ongoing work illuminating plant molecular responses to phloem-feeding insects.</p

Genetic selection for bovine chromosome 18 haplotypes associated with divergent somatic cell score affects postpartum reproductive and metabolic performance

The susceptibility of animals to periparturient diseases has a great effect on the economic efficiency of dairy industries, on the frequency of antibiotic treatment, and on animal welfare. The use of selection for breeding cows with reduced susceptibility to diseases offers a sustainable tool to improve dairy cattle farming. Several studies have focused on the association of distinct bovine chromosome 18 genotypes or haplotypes with performance traits. The aim of this study was to test whether selection of Holstein Friesian heifers via SNP genotyping for alternative paternal chromosome 18 haplotypes associated with favorable (Q) or unfavorable (q) somatic cell scores influences postpartum reproductive and metabolic diseases. Thirty-six heifers (18 Q and 18 q) were monitored from 3 wk before calving until necropsy on d 39 (± 4 d) after calving. Health status and rectal temperature were measured daily, and body condition score and body weight were assessed once per week. Blood samples were drawn twice weekly, and levels of insulin, nonesterified fatty acids, insulin-like growth factor-I, growth hormone, and β-hydroxybutyrate were measured. Comparisons between the groups were performed using Fisher's exact test, chi-squared test, and the GLIMMIX procedure in SAS. Results showed that Q-heifers had reduced incidence of metritis compared with q-heifers and were less likely to develop fever. Serum concentrations of β-hydroxybutyrate were lower and insulin-like growth factor-I plasma concentrations were higher in Q- compared with q-heifers. However, the body condition score and withers height were comparable between haplotypes, but weight loss tended to be lower in Q-heifers compared with q-heifers. No differences between the groups were detected concerning retained fetal membranes, uterine involution, or onset of cyclicity. In conclusion, selection of chromosome 18 haplotypes associated with a reduced somatic cell score resulted in a decreased incidence of postpartum reproductive and metabolic diseases in this study. The presented data add to the existing knowledge aimed at avoiding negative consequences of genetic selection strategies in dairy cattle farming. The underlying causal mechanisms modulated by haplotypes in the targeted genomic region and immune competence necessitate further investigation

The proteins encoded by the pogo-like Lemi1 element bind the TIRs and subterminal repeated motifs of the Arabidopsis Emigrant MITE: consequences for the transposition mechanism of MITEs

MITEs (miniature inverted-repeated transposable elements) are a particular class of defective DNA transposons usually present within genomes as high copy number populations of highly homogeneous elements. Although an active MITE, the mPing element, has recently been characterized in rice, the transposition mechanism of MITEs remains unknown. It has been proposed that transposases of related transposons could mobilize MITEs in trans. Moreover, it has also been proposed that the presence of conserved terminal inverted-repeated (TIR) sequences could be the only requirement of MITEs for mobilization, allowing divergent or unrelated elements to be mobilized by a particular transposase. We present here evidence for a recent mobility of the Arabidopsis Emigrant MITE and we report on the capacity of the proteins encoded by the related Lemi1 transposon, a pogo-related element, to specifically bind Emigrant elements. This suggests that Lemi1 could mobilize Emigrant elements and makes the Lemi1/Emigrant couple an ideal system to study the transposition mechanism of MITEs. Our results show that Lemi1 proteins bind Emigrant TIRs but also bind cooperatively to subterminal repeated motifs. The requirement of internal sequences for the formation of proper DNA/protein structure could affect the capacity of divergent MITEs to be mobilized by distantly related transposases