121 research outputs found

    Report of the 11th Liaison Meeting

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    The   11thLiaison   Meeting   between   the   Chairs   of   the   RCMs,   the   ICES   PGCCDBS,   PGMED  and  PGECON,  the  STECF  EWGs  on  the  DCF,  the  Regional  Database  Steering   Committees,  the  ICES  and  GFCM  representatives  and  the  European  Commission  was   held  at  the  DG  Maritime  Affairs  and  Fisheries,  Brussels  from  8th  to  9th  October  2014. The  11th  Liaison  meeting  was  held  in  Brussels  on  8th  and  9th  October  2014  to  address  the   following  terms  of  reference:     TOR  1.  Discussion  on  possible  follow-­‐‑up  to  the  main  outputs/recommendations  of:   • The  2014  RCMs  and  to  the   sp ecific  re commenda tions  a ddr e sse d  to  th e  Liaison   Meeting   • P G ECO N ,  PG CCDBS,  PG Med   –   ou tcome s  an d  r e commendation s  fr om  the ir   2014  meeting     • STECF  EWG  and  STEC F  Plen ary   -­‐‑   ou tcome s  a n d  r e commendation s  fr om  the ir   2014  meeting     • Data  end-­‐‑ users  (IC ES,  G F C M,  RC Ms)   TOR  2.  Compilation  of  recommendations  on  the  DCF   A  compilation  of  DCF  recommendations  will  be  established  by  the  COM  by  end  2014.   LM   needs   to   agree   on   which   recommendations   should   be   included   (i.e.   from   which   bodies)  &  covering  which  years.     TOR  3.  Regional  cooperation   • G r ants  for  str eng thene d  reg ion al  coop eration     • R e g ional  da ta b ases   o O ver view  of  use  of  the  Reg ional  Datab ases  for  R CMs  in  2014,  and  p rob lems   identified   o O ther  deve lop ments  (RDB  training s  in  2014,  RDB  Med&BS  develop ment)   o Chang es  for  the  fu tu re   –  an y  re commen da tions  from  th e  LM?   • R C M  data  calls   –  ove rview  of  h ow  MS  r esp onde d.   TOR  4.  Recommended  meetings/workshops   • P r ep a r e  a  list  of  r ecommen ded  me etin g s  for  2015  as  g u idance  for  MS   TOR  5.  Studies   • O ver view  of  p rocess   • LM  comme nts  and  p r ioritization  of  studies  p r op osed  b y  RC Ms,  PG ECO N ,  ICES,   GFCM   TOR  6.  AOB     1. The  DCF  website  has  been  revamped  by  the  JRC.  Any  comments  on  this?   2. Access  to  the  RCM  SharePoint   3. Derogations  –  List  of  derogations  by  Member  State  has  been  prepared  by  DG   MARE.  Have  any  RCMs  updated  this?     4. ICES  will  provide  an  update  on  their  plans  to  re-­‐‑evaluate  surveys.  Should  this   be  followed  by  STECF  work  on  surveys  to  be  included  in  future  EU  MAP?   5. Annual  reports  –  simplification:  presentation  of  process. 6. Data  transmission:   a. new   platform   for   information   exchanges   between   COM,   MS   and   end-­‐‑ users   b. new   tool   for   reporting   on   how   MS   complied   with   the   DG   MARE/JRC   data  calls     In   addition   to   the   above   Terms   of   Reference,   an   item   was   added   at   the   start   of   the   meeting,  regarding  the  implication  of  the  Landing  Obligation  on  data  collection  and   the  Discard  Plans.

    Multiple imputation for estimating hazard ratios and predictive abilities in case-cohort surveys

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    <p>Abstract</p> <p>Background</p> <p>The weighted estimators generally used for analyzing case-cohort studies are not fully efficient and naive estimates of the predictive ability of a model from case-cohort data depend on the subcohort size. However, case-cohort studies represent a special type of incomplete data, and methods for analyzing incomplete data should be appropriate, in particular multiple imputation (MI).</p> <p>Methods</p> <p>We performed simulations to validate the MI approach for estimating hazard ratios and the predictive ability of a model or of an additional variable in case-cohort surveys. As an illustration, we analyzed a case-cohort survey from the Three-City study to estimate the predictive ability of D-dimer plasma concentration on coronary heart disease (CHD) and on vascular dementia (VaD) risks.</p> <p>Results</p> <p>When the imputation model of the phase-2 variable was correctly specified, MI estimates of hazard ratios and predictive abilities were similar to those obtained with full data. When the imputation model was misspecified, MI could provide biased estimates of hazard ratios and predictive abilities. In the Three-City case-cohort study, elevated D-dimer levels increased the risk of VaD (hazard ratio for two consecutive tertiles = 1.69, 95%CI: 1.63-1.74). However, D-dimer levels did not improve the predictive ability of the model.</p> <p>Conclusions</p> <p>MI is a simple approach for analyzing case-cohort data and provides an easy evaluation of the predictive ability of a model or of an additional variable.</p

    Technical mitigation measures for sharks and rays in fisheries for tuna and tuna-like species: turning possibility into reality

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    Tuna fisheries have been identified as one of the major threats to populations of other marine vertebrates, including sea turtles, sharks, seabirds and marine mammals. The development of technical mitigation measures (MM) in fisheries is part of the code of conduct for responsible fisheries. An in-depth analysis of the available literature regarding bycatch mitigation in tuna fisheries with special reference to elasmobranchs was undertaken. Studies highlighting promising MMs were reviewed for four tuna fisheries (longline, purse seine, driftnets and gillnet, and rod and line – including recreational fisheries). The advantages and disadvantages of different MMs are discussed and assessed based on current scientific knowledge. Current management measures for sharks and rays in tuna Regional Fishery Management Organizations (t-RFMOs) are presented. A review of relevant studies examining at-vessel and postrelease mortality of elasmobranch bycatch is provided. This review aims to help fisheries managers identify pragmatic solutions to reduce mortality on pelagic elasmobranchs (and other higher vertebrates) whilst minimizing impacts on catches of target tuna species. Recent research efforts have identified several effective MMs that, if endorsed by t-RFMOs, could reduce elasmobranchs mortality rate in international tropical purse seine tuna fisheries. In the case of longline fisheries, the number of operational effective MMs is very limited. Fisheries deploying driftnets in pelagic ecosystems are suspected to have a high elasmobranchs bycatch and their discard survival is uncertain, but no effective MMs have been field validated for these fisheries. The precautionary bans of such gear by the EU and by some t-RFMOs seem therefore appropriate. Recreational tuna fisheries should be accompanied by science-based support to reduce potential negative impacts on shark populations. Priorities for research and management are identified and discussed.S

    Male gonadal dose of ionizing radiation delivered during X-ray examinations and monthly probability of pregnancy: a population-based retrospective study

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    BACKGROUND: Male gonadal exposure to ionizing radiation may disrupt spermatogenesis, but its influence on the fecundity of couples has been rarely studied. We aimed to characterize the influence of male gonadal dose of ionizing radiation delivered during radiodiagnostic on the monthly probability of pregnancy. METHODS: We recruited a random sample of women who retrospectively described 1110 periods of unprotected intercourse beginning between 1985 and 1999 and leading either to a live birth or to no pregnancy; their duration was censored after 13 months. The male partner answered a telephone questionnaire on radiodiagnostic examinations. We assigned a mean gonadal dose to each type of radiodiagnostic examination. We defined male dose for each period of unprotected intercourse as the sum of the gonadal doses of the X-ray examinations experienced between 18 years of age and the date of discontinuation of contraception. Time to pregnancy was analysed using a discrete Cox model with random effect allowing to estimate hazard ratios of pregnancy. RESULTS: After adjustment for female factors likely to influence fecundity, there was no evidence of an association between male dose and the probability of pregnancy (test of homogeneity, p = 0.55). When compared to couples with a male gonadal dose between 0.01 and 0.20 milligrays (n = 321 periods of unprotected intercourse), couples with a gonadal dose above 10 milligrays had a hazard ratio of pregnancy of 1.44 (95% confidence interval, 0.73–2.86, n = 31). CONCLUSION: Our study provides no evidence of a long-term detrimental effect of male gonadal dose of ionizing radiation delivered during radiodiagnostic on the monthly probability of pregnancy during the year following discontinuation of contraceptive use. Classification errors due to the retrospective assessment of male gonadal exposure may have limited the statistical power of our study

    The context of HIV risk behaviours among HIV-positive injection drug users in Viet Nam: Moving toward effective harm reduction

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    <p>Abstract</p> <p>Background</p> <p>Injection drug users represent the largest proportion of all HIV reported cases in Viet Nam. This study aimed to explore the perceptions of risk and risk behaviours among HIV-positive injection drug users, and their experiences related to safe injection and safe sex practices.</p> <p>Methods</p> <p>This study used multiple qualitative methods in data collection including in-depth interviews, focus group discussions and participant observation with HIV-positive injection drug users.</p> <p>Results</p> <p>The informants described a change in the sharing practices among injection drug users towards more precautions and what was considered 'low risk sharing', like sharing among seroconcordant partners and borrowing rather than lending. However risky practices like re-use of injection equipment and 'syringe pulling' i.e. the use of left-over drugs in particular, were frequently described and observed. Needle and syringe distribution programmes were in place but carrying needles and syringes and particularly drugs could result in being arrested and fined. Fear of rejection and of loss of intimacy made disclosure difficult and was perceived as a major obstacle for condom use among recently diagnosed HIV infected individuals.</p> <p>Conclusion</p> <p>HIV-positive injection drug users continue to practice HIV risk behaviours. The anti-drug law and the police crack-down policy appeared as critical factors hampering ongoing prevention efforts with needle and syringe distribution programmes in Viet Nam. Drastic policy measures are needed to reduce the very high HIV prevalence among injection drug users.</p

    Nutritional therapy and infectious diseases: a two-edged sword

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    The benefits and risks of nutritional therapies in the prevention and management of infectious diseases in the developed world are reviewed. There is strong evidence that early enteral feeding of patients prevents infections in a variety of traumatic and surgical illnesses. There is, however, little support for similar early feeding in medical illnesses. Parenteral nutrition increases the risk of infection when compared to enteral feeding or delayed nutrition. The use of gastric feedings appears to be as safe and effective as small bowel feedings. Dietary supplementation with glutamine appears to lower the risk of post-surgical infections and the ingestion of cranberry products has value in preventing urinary tract infections in women
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