9 research outputs found
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
- Annette Toellefsen
- Anthony Adenekan
- Anthony Radavidson
- Antigoni Karathanou
- Anton Turčan
- Antonella Cotoia
- Antonella Mo
- Antoni Margarit Ribas
- Antonia Liarmakopoulou
- Antonija Petosic
- Antonino Rizzo
- Antonio Abdala
- Antonio Barone
- Antonio Landaverde
- Antonio Manzo
- Antonio Margarit Ribas
- Antony Eneas
- Apostolos Bakas
- Arena Raimondo
- Arif Moghal
- Aristeidis Vakalos
- Arlette Van Den Elst
- Armanda Bozena
- Armando Schmukler
- Armorel Salberg
- Artemis Patsalos
- Arturo Briva
- Arvind Baronia
- Asbjorn Blondal
- Ascanio Tridente
- Ashish K Khanna
- Ashish K Khanna
- Ashish Khanna
- Ashley Szabo Eltorai
- Ashok Sundai Raj
- Ashwaq Ali
- Asmah Zainudin
- Asu Ozgultekin
- Ata Mahmoodpoor
- Athena Lavrentieva
- Attilio Quaini
- Audrey Fioretti
- Audrey Massard
- Auke Reidinga
- Auli Palmu
- Avşar Zerman
- Aya Alabuzidi
- Ayako Noguchi
- Ayça Gümüş
- Azmin Huda Abdul Rahim
- Babangida John Sankey
- Badiola Hilario
- Banu Taşdemir
- Baoke Zhang
- Barbara Garcia
- Barbro Meland
- Bart Ramaker
- Basri Mat Nor
- Battsetseg Baasanjav
- Başar Erdivanli
- Başar Erdivanli
- Beatrice Pastore
- Begoña Zalba-Etayo
- Belen Burgos Conde
- Belinda Guadi-Gosh
- Ben Attwood
- Benjamin Bongiorno
- Benjamin Gerretsen
- Benoît Chinardet
- Berenice Navarro
- Bernardo Panka
- Bernardo Panka
- Bernd Oliver Rose
- Bert Loef
- Betty Star Kampayana
- Beverley Thomas
- Beysim Özcan
- Beysim Özcan
- Bhagyesh Shah
- Biljana Kuzmanovska
- Bindu Thankamma
- Bing Song
- Binny Tuinstra
- Birgitte Fosser Johansen
- Birthe Husted
- Biyan Li
- Bjoern Monsen
- Bjorn Bratsberg
- Bodin Khwannimit
- Bogdan Raitsiou
- Bojan Jovanovic
- Bonnie Bowes
- Boğaç Özserezli
- Bram Kilapong
- Bram Kilapong
- Branislava Stefanovic
- Brian Marsh
- Brigitte Tejeda-Huezo
- Brita Fosser Olsen
- Britt Galaaen
- Britt Sjobo
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- Bronagh Blackwood
- Bruno Miguel Bispo
- Bruno Sousa
- Bruno Sousa
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- Burhan Hadri
- Burhan Hadri
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- Caihong Hui
- Caiju Song
- Caitriona Cody
- Can Turan
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- Carlos Alejandro Bascary
- Carlos Castro Delgado
- Carmel Chapman
- Carmel Georgiev
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- Cecilia Inés Loudet
- Cecilia Loudet
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- Chaoqun Ma
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- Charlotte Carter
- Charlotte Young
- Charlotte Young
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- Cheng
- Chenghau Mu
- Chengxia Sun
- Cheryl Bealer
- Cheryl Davidson
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- Chiara Megna
- Cho Young-Jae
- Chris Gerome Ellazar
- Chris Smith
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- Christian Ferretti
- Christian Frey
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- Christine Fiedler
- Christine Sheehan
- Christophe Borin
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- Christopher Barnes
- Christopher Barnes
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- Damei Wang
- Damien O'Connell Rosemary Finn
- Dana Tomescu
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- Daniel Blanco
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- Daniel Owens
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- Vincianne Pleitinckx
- Virginie Souppart
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- Vitaly Gusarev
- Vitaly Gusarov
- Vitor Gomes
- Vitor Manuel Vaz Pinto
- Viveca Hamback Hellkvist
- Višnja Nesek Adam
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- Vladimir Kulakov
- Vladislav Belskiy
- Volkan Inal
- Volodymyr Babych
- Vongayi Ogbeide
- W Nazaruddin W Hassan
- Walid Naija
- Walid Sellami
- Walter Swinnen
- Wan Nasrudin Wan Ismail
- Wang Zhijuan
- Wangari Waweru-Siika
- Wangari Waweru-Siika
- Wangyan Jin
- Wei Sun
- Wei Wang
- Wei Wei
- Wei Zhang
- Wei Zhang
- Weilian Yuan
- Weiwei Li
- Wenche Arntsen
- Wendy Brown
- Wendy Chaboyer
- Wendy Chaboyer
- Wendy Milner
- Wenjie Ju
- Wenmei Wang
- Wenmin Chen
- Wenwen Zhao
- Wenzhen Cao
- Wesal Ali Belkhair
- Willem Dieperink
- Windu Baskoro
- Won-Yeon Lee
- Wu Yuchen
- Xia Cui
- Xia Huang
- Xianhong Zheng
- Xianping Luo
- Xiao Fang Tian
- Xiao Xu
- XiaoChun Hu
- Xiaodi Liu
- Xiaofang Luo
- Xiaohan Li
- Xiaohan Li
- Xiaojun Wu
- Xiaoli Yan
- Xiaomin Wang
- Xiaoqiong Deng
- Xiaowu Bai
- Xiaoyan Chen
- Xiaoyan Chen
- Xiaoying Wu
- XiaoZhe Liu
- Ximena Villanueva
- Xingguo Li
- Xinhua Xia
- Xinhua Xia
- Xinjian Li
- Xinran Ding
- Xinxia Li
- Xinxia Li
- Xiuhua Fang
- Xiuhua Fang
- Xiujuan Xue
- XiuMei Liu
- Xiuying Yao
- Xiyan Wei
- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
- Yalım Dikmen
- Yalım Dikmen
- Yalim Dikmen
- Yan Gao
- Yan Li
- Yan Liu
- Yan Liu
- Yan Long
- Yan Wan
- Yan Wang
- Yan Xiao
- Yan Xie
- Yan Xu
- Yan Yan
- Yanfei Long
- Yang Lei
- Yang Liu
- Yang Wu
- Yang Xiaoyan
- Yanhong Di
- Yanhua Hao
- Yani Tian
- Yanlan Yao
- Yanling Shen
- Yanman Jian
- Yanmei Gu
- Yanming Ding
- Yann Le Guen
- Yanping Yang
- Yasser Mandourah
- Yenny Cardenas
- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
- Ying Wang
- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
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- Wahab Sherliza
- Wahlbom Ewa
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- Xiaoyan Yang
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- Xing Cynthia
- Xiong Yunfeng
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- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
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- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
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- Yeon-Joo Lee
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- Yilmaz Hakan
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- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
- Baumber Rachel
- Baxter Karen
- Bayraktar Yesim Serife
- Bealer Cheryl
- Bean Sarah
- Becker Cathy
- Becker Delmiro
- Behan Helena
- Beker Tatjana
- Bekos Vasileios
- Belii Adrian
- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
- Bench Suzanne
- Bendelari Valentina
- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
- Bestle Morten
- Beuret Pascal
- Bhakhtiani Lakshay
- Bhargava Vaibhav
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- Bilawicz Jan
- Binda Filipo
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- Birgisdóttir Hrönn
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- Blanco Maria Pilar Sogues
- Blasco Maria Luisa
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- Blondal Asbjorn
- Bloos Frank
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- Bo Qi
- Bocui Nie
- Boedjawan Naraindath N.
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- Bogoevska-Miteva Zaneta
- Bonaccorso Luciano
- Bongiorno Benjamin
- Bonsignore Pablo Julio Maldonaldo
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- Bormans Laura
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- Bowes Bonnie
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- Bösl Kathrin
- Cabral Dolly Mabel Bordon
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- Corcoran Ailesh
- Coremans Stefano
- Correia Malcolm C.
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- Dayan Meneses
- de Almeida Angelica Olivetto
- de Anda Gilberto Felipe Vazquez
- De Bels David
- de Ceballos José Peral Gutierrez
- De Decker Koen
- De Haan Marina
- de Jesús Ortiz Alberto
- de la Ventana Ana Belén Sánchez
- De lange Dylan
- De Lange Dylan
- de Molina Serrano José Ivan Rodriguez
- De Montmollin Etienne
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- De Rosa Silvia
- De Sanctis Francesca
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- Delgado Patricia
- Dellafiore Federica
- Delossantos Shella
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- Somerville Justine
- Sona Carrie
- Song Bing
- Song Caiju
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- Song Min
- Song Rima
- Sosa Miguel Ángel
- Sosnowski Kellie
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- Soula Enas
- Soulisse Léa
- Soundoulounaki Stella
- Souppart Virginie
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- Sousa Bruno
- Spadaro Savino
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- Spyropoulou Anastasia
- Spångfors Martin
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- Staikos Ioannis
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- Starchenko Irina
- Stefanovic Branislava
- Steffenak Elin
- Stehr Sebastian
- Stenset Ane
- Stiban Sonia
- Stivanello Lucia
- Stojanovic Milena
- Stones Elizabeth
- Straede Esben
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- Subedi Nisha Bhandari
- Suen Gabriel
- Sulaiman Siti Rohayah
- Sun Chengxia
- Sun Wei
- Sun Yue
- Susanti Ade
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- Swinnen Walter
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- Tababa Osama Wanees Emhemid
- Tabah Alexis
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- Takahashi Kenji
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- Twagirumugabe Theogene
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- van Axel Alisha
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- Van Den Brink Mark
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- Van Vliet Peter
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- Varela Maria
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- Vaughan-Jones Nicola
- Velickovic Jelena
- Veličković Dejan
- Ventour Dale
- Vermeijden Jan Wytze
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- Villa Robert
- Villafuerte Missael Vladimir Espinoza
- Villanueva Ximena
- Villegas Paula
- Viveiros Abel
- Vizcaychipi Marcela
- Vlaovic Janko
- Vochin Ana
- Volta Carlo Alberto
- von der Osten Ingrid
- Von Der Osten Ingrid
- von Lewinski Dirk
- Vosylius Saulius
- Vuković Anita
- Vullum Sylvi
- Vymazal Tamas
- Vymazal Tomas
- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
- Wang Damei
- Wang Fanglan
- Wang GuoXian
- Wang Hai Yun
- Wang Haiyan
- Wang Jing
- Wang Kefang
- Wang LingLing
- Wang RuiXia
- Wang Shuhui
- Wang Shuo
- Wang Wei
- Wang Wenmei
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- Wang Yan
- Wang Ying
- Wang Yingli
- Wang Yuping
- Wang Yuxia
- Watts Stacey
- Waweru-Siika Wangari
- Wei Dongfang
- Wei Wei
- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
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- Whitticase Richard
- Wiborg Elisabeth
- Wijnands Patricia
- Wilby Liz
- Williams Anne
- Williams Ged
- Williams Helen
- Williams Karen
- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
- Wu Juan
- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
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- Yuan Cui
- Yuan Weilian
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- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
Vaginal metastasis as the initial presentation of leiomyosarcoma: a case report
- Author
- A Ly
- AA Sandberg
- B Davidson
- Cecilia Villalaín-González
- CG Tropé
- DS Kapp
- E D'Angelo
- F Amant
- F Moinfar
- FIGO commitee on gynecologic Oncology
- Gregorio López-González
- H Hwang
- H Kobayashi
- Jesús S. Jiménez-López
- JH Nam
- K Galaal
- M Carmen Binda del
- Ma. Reyes Oliver-Perez
- ME Sherman
- MM Allen
- NS Reed
- P Pautier
- Patricia Lopez-Garcia
- RJ Kurman
- RL Giuntoli 2nd
- RL Giuntoli 2nd
- SD Peddada
- SH Tirumani
- SM Ueda
- SW Bell
- V Cantisani
- VM Abeler
- VM Abeler
- Y Ravid
- Álvaro Tejerizo-García
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial
- Author
- Abrate Paolo
- Accordino Silvia
- Ageno Walter
- Agnoletti Vanni
- Agosti Michele
- Agostini Carlo
- Agostini Moreno
- Agostinone Adriana
- Agrati Antonio Maria
- Aiello Giuseppe
- Aiuti Massimo
- Albano Giovanni
- Alberico Marielisa
- Alborghetti Armando
- Alborghetti Leonardo
- Aldegheri Giorgio
- Allevi Elisabetta
- Amadasi Silvia
- Amaglio Angelo
- Amitrano Maria
- Amoroso Filippo
- Andrea Antonini
- Andrea Bellone
- Andreassi Silvia
- Andreoni Massimo
- Angarano Gioacchino
- Angeletti Chiara
- Angelici Stefano
- Angheben Andrea
- Angileri Manuela
- Angrisani Claudio
- Annnunziata Maria Laura
- Annunziata Anna
- Anselmo null
- Ansuini Andrea
- Antivalle Marco
- Antonio Fioravanti
- Antonioli Chiara Maria
- Aondio Gianmarco
- Appiani Camilla
- Aquilini Donatella
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- Arcoleo Giuseppe
- Arenare Laura
- Arenare Laura
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- Artiol Stefania
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- Ascierto Paolo Antonio
- Ascierto Paolo Antonio
- Ashofarir Najat
- Atripaldi Luigi
- Atripaldi Luigi
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- Genovese Elvira
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- Ghidoni Giulia
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- Guidelli Giacomo Maria
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- Gulisano Leonardo
- Harari Sergio
- Henchi Sonia
- Hofer Alex
- Iacobello Carmelo
- Iemoli Enrico
- Iengo Bianca
- Ilaria Blangetti
- Imitazione Pasquale
- Imperiale Daniele
- Inchiostro Sandro
- Infantino Gessica
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- Marrocco-Trischitta Massimiliano M.
- Marrocco-Trischitta Massimiliano M.
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- Mauro Immacolata
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- Mei Federico
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- Mosca Giacomo
- Moschini Greta
- Mosti Silvia
- Motta Leonardo
- Mucci Luciano
- Muiesan Maria Lorenza
- Muiesan Maria Lorenza
- Murdaca Giuseppe
- Mussini Cristina
- Mussini Cristina
- Musumeci Diana
- Muttini Stefano
- Nallino Gabriella
- Napoli Giovanna
- Nardecchia Anna Laura
- Nardi Stefano
- Nasta Paola
- Nava Antonella
- Nava Valeria
- Navalesi Paolo
- Navarra Mauro
- Negri Emanuele Alberto
- Negri Emanuele Alberto
- Negro Cristina
- Negro Enrica
- Nespola Giorgio Amadio
- Nicastri Emanuele
- Nico Andrea
- Nicolini Laura Ambra
- Nijhawan Parni
- Niro Dario
- Nonini Sandra
- Noto Concetta
- Nouvenne Antonio
- Novali Mauro
- Nucera Antonia
- Nucera Gabriella
- Nuceri Antonia
- Numis Fabio Giuliano
- Odolini Silvia
- Oggionni Tiberio
- Olivetti Alessandro
- Omega Luca
- Oppedisano Peppino
- Orlandi Matteo
- Ornella Calderone
- Otero Manuela
- Ottaviano Mario
- Pace Erminio
- Pacentra Enrico
- Pacetti Veronica
- Pagani Silvia
- Pagliano Pasquale
- Pagnoni Carlo
- Pagnozzi Fiammetta
- Paini Anna
- Palagano Nicolas
- Palla Marco
- Palladino Marcello
- Pallotto Carlo
- Palmieri Fabrizio
- Palmiero Gerardo
- Palmiotti Giuseppe Antonio
- Palumbo Michele
- Pampaloni Alessio
- Panaccione Anna
- Pandini Chiara Stefania
- Panese Sandro
- Panico Rosanna
- Pannella Greta
- Panzolato Gianluigi
- Paone Tonia Celeste
- Papetti Claudia
- Papi Alberto
- Para Ombretta
- Parrella Roberto
- Parrella Roberto
- Parrocchia Sergio
- Parruti Giustino
- Pascale Renato
- Pasero Daniela
- Pasini Simone Marino
- Pasquini Zeno
- Pasquino Bernadetta
- Pasquino Paola
- Passalacqua Rodolfo
- Pastorelli Mauro
- Pasulo Luisa
- Pavei Chiara
- Pavoni Vittorio
- Peci Paolo
- Pedrini Luciano
- Pelagatti Lorenzo
- Pensa Anna
- Pepe Antonio
- Perego Giovanni Battista
- Peregrinelli Alessio
- Perfetti Elisa
- Perin Tiziana
- Peris Adriano
- Perra Roberto
- Perrone Francesco
- Perrone Francesco
- Perugini Orietta
- Pesce Laura
- Petrone Anna
- Petrosillo Nicola
- Piazza Manuela
- Piazza Ornella
- Piccinni Rosangela
- Piccirillo Maria Carmela
- Piccirillo Maria Carmela
- Piccoli Jolanda
- Piconi Stefania
- Pieralli Filippo
- Pierantozzi Silvia
- Pierfranceschi Matteo Giorgi
- Pierini Simona
- Pietrangelo Antonello
- Piga Sandro
- Pignatti Andrea
- Piluso Martina
- Pinelli Giovanni
- Pinna Simone Mornese
- Pirozzi Maria Rosa
- Pisapia Raffaella
- Pisterna Alessia
- Pitagora Loredana
- Piva Simone
- Plamieri Giulia
- Poggesi Loredana
- Pognuz Erik Roman
- Poisa Paolo
- Polati Enrico
- Poletti Enrico
- Poletti Venerino
- Poli Federica
- Poli Marco Dei
- Polistina Giorgio
- Pollastri Costanza
- Pontali Emanuele
- Ponticiello Antonio
- Pontiggia Silvia
- Pontremoli Roberto
- Popoli Patrizia
- Porta Francesca Della
- Porta Giovanni
- Portale Grazia
- Potenza Domenico
- Prandini Paolo
- Presotto Fabio
- Prestini Katiela
- Principi Tiziana
- Properzi Martina
- Prozzo Alessandra
- Pulitanò Grazia
- Pulvirenti Fabrizio
- Punzi Rodolfo
- Puorto Antonella
- Puoti Massimo
- Pusterla Luigi
- Puttini Camilla
- Quadri Rachele Delli
- Racagni Milena
- Raffaeli Davide
- Raffaelli Valentina
- Raimondo Mariangela
- Rampa Lorenzo
- Ranghitta Melania
- Ranucci Marco
- Rapisarda Giuseppe
- Raponi Gianna
- Rastelli Gianni
- Rastellino Valentina
- Raumer Luigi
- Ravaglia Claudia
- Ravagnani Viviana
- Ravani Serena
- Regazzetti Angelo
- Reghenzi Piera
- Regis Monica
- Repossi Alice
- Rescigno Carolina
- Resimini Silvia
- Resta Marco
- Reta Massimo
- Ribecco Maria Teresa
- Riccardi Ferdinando
- Riccardi Niccolò
- Ricchiardi Alberto
- Ricci Chiara
- Ricci Clara
- Ricci Maria Anastasia
- Ricci Massimo
- Ricci Silvano
- Riccio null
- Ricioppo Aristodemo
- Ridola Lorenzo
- Riggio Oliviero
- Righetti Giulia
- Righini Erminio
- Ripamonti Diego
- Ripamonti Diego
- Rivitti Rosario
- Rizzardini Giuliano
- Rizzi Eleonora
- Rizzoni Damiano
- Roberti Giuseppe
- Roccaro Aldo
- Roccatello Dario
- Rocchetti Chiara
- Rocco Monica
- Roldan Eugenia Quiros
- Romagnoli Micaela
- Romanelli Michela
- Romano Anacleto
- Romano Annamaria
- Romano Fiorella
- Romeo Domenico
- Romeo Francesca
- Roncaglia Enrica
- Ronconi Maurizio
- Rossati Antonella
- Rossetti Barbara
- Rossi Alberto
- Rossi Nicolò
- Rossini Tizana
- Roveda Elena
- Rovere Pierangelo
- Ruggeri Ruggero
- Ruggieri Annamaria
- Ruggieri Lorenzoa
- Ruggieri Maria Paola
- Russo Chiara
- Russo Gianluca
- Russo Grazia
- Russo null
- Russo Roberto
- Rutili Maria Serena
- Sabato Eugenio
- Sabatti Maria Cecilia
- Sachs Michele
- Saffioti Carolina
- Saglimbene Sebastiana
- Sainaghi Pier Paolo
- Sala Girolamo
- Sala Luca
- Sala Nadia
- Salerno Anna Maria
- Salerno Nicola Duccio
- Salerno Nicola Duccio
- Salsi Pierpaolo
- Saltori Martino
- Salvarani Carlo
- Salvarani Carlo
- Salvetti Massimo
- Sangiovanni Antonella
- Sangiovanni Vincenzo
- Santantonio Teresa Antonia
- Santilli Giuseppina
- Santini Luca
- Santoboni Gianluca
- Santopuoli Donato
- Santoro Armando
- Saracco Marta
- Saracino Annalisa
- Sarmati Loredana
- Sarni Antonella
- Sarteschi Giovanni
- Sartori Enrico
- Satira Roberto
- Savi Maria Laura
- Savio Alfonso
- Savio Maria Cristina
- Sbreglia Costanza
- Scabini Silvia
- Scaglione Nadia
- Scala Alberto
- Scalabrino Elisa
- Scapino Bruno
- Scarafino Antonio
- Scarano Francesco
- Scartabellati Alessandro
- Schettino Clorinda
- Schettino Clorinda
- Schettino Giuseppe
- Scimonello Guglielmo
- Sciolè Katiuscia
- Scolari Francesco
- Scollet Sabino
- Scorletti Eva
- Scotto Riccardo
- Scotton Pier Giorgio
- Scozzafava Mariano
- Scudellari Roberta
- Sdanganelli Antonia
- Sellitto Carmine
- Sepulcri Chiara
- Serao Mattia
- Serati Lisa
- Serino Francesco Saverio
- Serra Eugenio
- Servillo Giuseppe
- Sgarabotto Camilla
- Sicheri Domenico
- Sighieri Cinzia
- Silengo Daniela
- Silva Matteo
- Silvia Tamanini
- Sirignano Emanuele
- Sorrentino Carlo
- Sortino Claudio
- Spadoni Claudia
- Spagnolli Walter
- Spagnuolo Giovanni
- Spanu Paolo
- Sparavigna Lucia
- Spatafora Mario
- Spatarella Micaela
- Spaziani Sandra
- Spina Rosario
- Spinicci Michele
- Spizzo Gilbert
- Spolveri Stefano
- Sportato Giuseppe
- Squillace Nicola
- Squillace Nicola
- Stefanetto Ivana Marina
- Stellini Roberto
- Stillante Maria Serafina
- Stobbione Paolo
- Storti Angelo
- Storti Enrico
- Straface Giuseppe
- Strano Giuseppe
- Stroppa Elisa Maria
- Suardi Lorenzo Roberto
- Succu Angela
- Tacconelli Evelina
- Tacconi Danilo
- Tafuri Agostino
- Taglietti Fabrizio
- Taibi Chiara
- Tarquini Giovanna
- Tarsia Paolo
- Tasca Francesca
- Tebaldi Alessandra
- Tedeschi Alberto
- Tedeschi Sara
- Tedesco Andrea
- Tedesco Silvia
- Tenti Elena
- Teopompi Elisabetta
- Testa Filippo
- Teti Elisabetta
- Ticinesi Andrea
- Tieghi Tiziana
- Tinti Maria Giulia
- Titolo Giancarlo
- Tognella Silvia
- Tomasoni Gabriele
- Tomasoni Lina
- Tomasoni Lina Rachele
- Topino Simone
- Tornese Daniela
- Torre Federica
- Torretta Giacomo
- Torrini Monica
- Tosti Andrea
- Traballi Gabriella
- Trenti Chiara
- Trequattrini Tiziana
- Trezzi Michele
- Trojaniello Claudia
- Tropea Concetta Maria Gabriella
- Tundo Paolo
- Tura Paolo
- Turati Maria Luisa
- Turrini Mauro
- Uccella Ilaria
- Uccelli Maria Cristina
- Ucciferri Claudio
- Uggeri Cristiano
- Urru Silvana
- Ursillo Antonia
- Usai Carlo Andrea
- Vacca Elisabetta Blasi
- Vairo Giuseppe
- Valastro Federico
- Valenti Marco
- Valenti Vincenzo
- Valenzi Emiliano
- Valli Linda
- Vallone Alfredo
- Vanoni Nicolò
- Varbella Ferdinando
- Vassia Veronica
- Vecchiet Jacopo
- Vella Sabrina
- Venturi Bruna
- Venturini Sergio
- Verhovez Andrea
- Veronese Lorenzo
- Versaci Alessandra
- Vetica Angelo
- Vezzoli Monia
- Viale Pierluigi
- Vianello Andrea
- Vico Carmen
- Vigliarolo Rossana
- Viglietti Rosaria
- Vincenti Antonella
- Vincenzi Marcello
- Vincenzo Brianti
- Vincenzo Valiani
- Viola Emanuela
- Viri Sabrina
- Virzì Giuseppe
- Visconti Giuseppe
- Visconti Stefano
- Visetti Enrico Maria
- Vitale Francesco
- Vitale Giovanni
- Vitale Maria Grazia
- Vitiello Leonarda
- Vitiello Silvio
- Viva Tommaso
- Viviani Rosangela
- Volkl Thomas
- Volpato Francesca
- Volta Carlo Alberto
- Vuotto Pietro
- Zammarchi Lorenzo
- Zanardini Cristina
- Zanatta Paolo
- Zanini Barbara
- Zanini Paola
- Zannetti Pio
- Zanolini Gabriele
- Zappa Maria Crisitna
- Zappulo Emanuela
- Zavarise Paola
- Zeme Angela Daniela
- Zenoni Davide
- Zini Enea
- Zoia Elena
- Zotti Maria Gioconda
- Zuccalà Francesco
- Zuccalà Paola
- Zuccarini Andrea
- Zummo Ugo
- Zunino Alessia
- Publication venue
- Publication date
- 01/01/2020
- Field of study
BackgroundTocilizumab blocks pro-inflammatory activity of interleukin-6 (IL-6), involved in pathogenesis of pneumonia the most frequent cause of death in COVID-19 patients.MethodsA multicenter, single-arm, hypothesis-driven trial was planned, according to a phase 2 design, to study the effect of tocilizumab on lethality rates at 14 and 30 days (co-primary endpoints, a priori expected rates being 20 and 35%, respectively). A further prospective cohort of patients, consecutively enrolled after the first cohort was accomplished, was used as a secondary validation dataset. The two cohorts were evaluated jointly in an exploratory multivariable logistic regression model to assess prognostic variables on survival.ResultsIn the primary intention-to-treat (ITT) phase 2 population, 180/301 (59.8%) subjects received tocilizumab, and 67 deaths were observed overall. Lethality rates were equal to 18.4% (97.5% CI: 13.6-24.0, P=0.52) and 22.4% (97.5% CI: 17.2-28.3, P<0.001) at 14 and 30 days, respectively. Lethality rates were lower in the validation dataset, that included 920 patients. No signal of specific drug toxicity was reported. In the exploratory multivariable logistic regression analysis, older age and lower PaO2/FiO2 ratio negatively affected survival, while the concurrent use of steroids was associated with greater survival. A statistically significant interaction was found between tocilizumab and respiratory support, suggesting that tocilizumab might be more effective in patients not requiring mechanical respiratory support at baseline.ConclusionsTocilizumab reduced lethality rate at 30 days compared with null hypothesis, without significant toxicity. Possibly, this effect could be limited to patients not requiring mechanical respiratory support at baseline.Registration EudraCT (2020-001110-38); clinicaltrials.gov (NCT04317092)
Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial
- Author
- Adriana Agostinone
- Adriano Basile
- Adriano Gravina
- Adriano Gravina
- Adriano Peris
- Agata Belsito
- Agostino Tafuri
- Alarico Ariani
- Alberto Baratta
- Alberto Catania
- Alberto Guerra
- Alberto Maraolo
- Alberto Papi
- Alberto Ricchiardi
- Alberto Rossi
- Alberto Scala
- Alberto Tedeschi
- Aldo Roccaro
- Alessandra Brocchieri
- Alessandra Cattaneo
- Alessandra Ferrari
- Alessandra Manini
- Alessandra Maria Cemuschi
- Alessandra Mecozzi
- Alessandra Prozzo
- Alessandra Tebaldi
- Alessandra Versaci
- Alessandro Bordonali
- Alessandro Cerutti
- Alessandro Di Filippo
- Alessandro Ferrari
- Alessandro Mastroianni
- Alessandro Meli
- Alessandro Morettini
- Alessandro Olivetti
- Alessandro Scartabellati
- Alessia Pisterna
- Alessia Zunino
- Alessio Lipari
- Alessio Maroccia
- Alessio Pampaloni
- Alessio Peregrinelli
- Alex Hofer
- Alfonso Masullo
- Alfonso Savio
- Alfredo Marinelli
- Alfredo Molteni
- Alfredo Molteni
- Alfredo Vallone
- Alice Moroni
- Alice Repossi
- Amalia Buglione
- Ambrogio Curtolo
- Amelia Filippelli
- Anacleto Romano
- Anaflorina Matei
- Andrea Angheben
- Andrea Ansuini
- Andrea Antonini
- Andrea Ballarin
- Andrea Ballotta
- Andrea Bellone
- Andrea Bianchin
- Andrea Biondi
- Andrea Boschi
- Andrea Calcagno
- Andrea Caruso
- Andrea Castellan
- Andrea Dalbeni
- Andrea De Monte
- Andrea De Vito
- Andrea Di Lorenzo
- Andrea Doria
- Andrea Fadda
- Andrea Frascati
- Andrea Gallo
- Andrea Giachi
- Andrea Magnaca
- Andrea Manzi
- Andrea Marco Machiavelli
- Andrea Marino
- Andrea Montisci
- Andrea Nico
- Andrea Pignatti
- Andrea Tedesco
- Andrea Ticinesi
- Andrea Tosti
- Andrea Verhovez
- Andrea Vianello
- Andrea Zuccarini
- Angel Bianchetti
- Angela Beltrame
- Angela Daniela Zeme
- Angela Iuorio
- Angela Succu
- Angelo Amaglio
- Angelo Gardellini
- Angelo Regazzetti
- Angelo Storti
- Angelo Vetica
- Anna Annunziata
- Anna Carraro
- Anna Gandino
- Anna Laura Nardecchia
- Anna Lingua
- Anna Mandelli
- Anna Maria Bella
- Anna Maria Caputo
- Anna Maria Cattelan
- Anna Maria Di Carlo
- Anna Maria Marata
- Anna Maria Salerno
- Anna Paini
- Anna Panaccione
- Anna Pensa
- Anna Petrone
- Annalisa Brianti
- Annalisa Campomori
- Annalisa Filtz
- Annalisa Mancini
- Annalisa Saracino
- Annamaria Corsaro
- Annamaria Romano
- Annamaria Ruggieri
- Annunziata De Rosa
- Anselmo Riccio
- Antoenlla Grisolia
- Antonella Bianco
- Antonella Caminati
- Antonella D'arminio Monforte
- Antonella Farina
- Antonella Frattari
- Antonella Lucci
- Antonella Nava
- Antonella Puorto
- Antonella Rossati
- Antonella Sangiovanni
- Antonella Sarni
- Antonella Vincenti
- Antonello Ciccone
- Antonello Pietrangelo
- Antonia Del Giudice
- Antonia Nucera
- Antonia Nuceri
- Antonia Sdanganelli
- Antonia Ursillo
- Antonietta Barone
- Antonina Carai
- Antonina Franco
- Antonino Mazzone
- Antonio Arcidiacono
- Antonio Capuozzo
- Antonio Carlotto
- Antonio Cherubini
- Antonio Daniele
- Antonio Fioravanti
- Antonio Greco
- Antonio Maria Agrati
- Antonio Mastroianni
- Antonio Messina
- Antonio Nouvenne
- Antonio Pepe
- Antonio Ponticiello
- Antonio Riccardo Buonomo
- Antonio Scarafino
- Arianna Manini
- Aristodemo Ricioppo
- Armando Alborghetti
- Armando Leone
- Armando Santoro
- Arturo Ciccullo
- Arturo Montineri
- Attilio Antonio Montano Bianchi
- Augusta Consorte
- Balan Dorina
- Barabara Baronio
- Barbara Cimolato
- Barbara Fiorini
- Barbara Mantovani
- Barbara Rossetti
- Barbara Zanini
- Beatrice Gasperini
- Benedetto Maurizio Celesia
- Bernadetta Pasquino
- Bernardino Mastropasqua
- Bianca Iengo
- Blanca Martinez Lopez De Arroyabe
- Blangetti Ilaria
- Blerta Kertusha
- Brianti Vincenzo
- Bruna Venturi
- Bruno Cacopardo
- Bruno Scapino
- Camilla Appiani
- Camilla Di Nunzio
- Camilla Fabbri
- Camilla Graziosi
- Camilla Puttini
- Camilla Sgarabotto
- Camillo Gnessi
- Carla Damiani
- Carlo Agostini
- Carlo Alberto Volta
- Carlo Andrea Usai
- Carlo Calzetti
- Carlo Calzetti
- Carlo Cappelli
- Carlo Meschini
- Carlo Moroni
- Carlo Pagnoni
- Carlo Pallotto
- Carlo Pallotto
- Carlo Salvarani
- Carlo Salvarani
- Carlo Sorrentino
- Carmelo Iacobello
- Carmelo Mangano
- Carmen Vico
- Carmine Cosentino
- Carmine Sellitto
- Carolina Rescigno
- Carolina Saffioti
- Casa Di Cura Villa Giada Pallotti
- Caterina Mengoli
- Caviglia Enrica
- Cecilia Bussolari
- Cecilia Monacci
- Cesarina Facchini
- Chiara Angeletti
- Chiara Baldessari
- Chiara Capitanio
- Chiara Citterio
- Chiara Costa
- Chiara Francisco
- Chiara Gallazzi
- Chiara Iommelli
- Chiara Lazzeri
- Chiara Maria Antonioli
- Chiara Molteni
- Chiara Montrucchio
- Chiara Pavei
- Chiara Ricci
- Chiara Rocchetti
- Chiara Russo
- Chiara Sepulcri
- Chiara Stefania Pandini
- Chiara Taibi
- Chiara Trenti
- Chiara Trenti
- Christian Dejaco
- Cinzia Cappi
- Cinzia Sighieri
- Ciro Canetta
- Ciro Gallo
- Ciro Gallo
- Clara Bartolaminelli
- Clara Ricci
- Claudia Bisio
- Claudia Cardone
- Claudia Cardone
- Claudia De Filippi
- Claudia Papetti
- Claudia Ravaglia
- Claudia Spadoni
- Claudia Trojaniello
- Claudio Angrisani
- Claudio Bellintani
- Claudio Fara
- Claudio Francesco
- Claudio Gentilini
- Claudio Maria Mastroianni
- Claudio Mastroianni
- Claudio Norbiato
- Claudio Sortino
- Claudio Ucciferri
- Clorinda Schettino
- Clorinda Schettino
- Concetta Maria Gabriella Tropea
- Concetta Noto
- Cosmo Del Borgo
- Costantino Fontana
- Costanza Malcontenti
- Costanza Pollastri
- Costanza Sbreglia
- Cristiana Seravalle
- Cristiano Matteo Carbonelli
- Cristiano Uggeri
- Cristina Baré
- Cristina Bernardi
- Cristina Bianchi
- Cristina Bretto
- Cristina Mussini
- Cristina Mussini
- Cristina Negro
- Cristina Zanardini
- Damiano Bragantini
- Damiano Rizzoni
- Daniela Barzan
- Daniela Bettini
- Daniela Boccalatte
- Daniela Bokor
- Daniela Cicognini
- Daniela De Franco
- Daniela Di Sanzo
- Daniela Emanuela Di Stefano
- Daniela Francisci
- Daniela Gori
- Daniela Labella
- Daniela Maccari
- Daniela Pasero
- Daniela Silengo
- Daniela Tornese
- Daniele Cosseta
- Daniele De Candia
- Daniele De Nardo
- Daniele Generali
- Daniele Imperiale
- Danilo Tacconi
- Dario Galante
- Dario Galante
- Dario Niro
- Dario Roccatello
- David Micarelli
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- Tommaso Viva
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- Ugo Zummo
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- Venerino Poletti
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- Vincenzo Bianco
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- Walter Ageno
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- Ylenia Berté
- Zaira Di Rosa
- Zeno Pasquini
- Zocchetti Cristina
- Publication venue
- Publication date
- 01/01/2021
- Field of study
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- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
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- Wu Xiaoying
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- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
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- Ye Mei
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- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
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- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 20/05/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
- Baumber Rachel
- Baxter Karen
- Bayraktar Yesim Serife
- Bealer Cheryl
- Bean Sarah
- Becker Cathy
- Becker Delmiro
- Behan Helena
- Beker Tatjana
- Bekos Vasileios
- Belii Adrian
- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
- Bench Suzanne
- Bendelari Valentina
- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
- Bestle Morten
- Beuret Pascal
- Bhakhtiani Lakshay
- Bhargava Vaibhav
- Bi AiPing
- Bianchini Suzana
- Bielskute Egidija
- Bilawicz Jan
- Binda Filipo
- Birgisdottir Hrönn
- Birgisdóttir Hrönn
- Bispo Bruno Miguel
- Biston Patrick
- Bjorgen Hege
- Blackwood Bronagh
- Blanc Agnès
- Blanco Daniel
- Blanco Maria Pilar Sogues
- Blasco Maria Luisa
- Bliksted Inger Abildgaard
- Blondal Asbjorn
- Bloos Frank
- Blot Stijn I.
- Bo Qi
- Bocui Nie
- Boedjawan Naraindath N.
- Bogarin Javier
- Bogoevska-Miteva Zaneta
- Bonaccorso Luciano
- Bongiorno Benjamin
- Bonsignore Pablo Julio Maldonaldo
- Borgognoni Cinzia
- Borin Christophe
- Borkowska Marta
- Bormans Laura
- Boroli Filippo
- Borys Michal
- Boschetto Margherita
- Bossolasco Matteo
- Bota Marc
- Boulanger Carole
- Boulton Karen
- Bowes Bonnie
- Boyer Laetitia
- Bozbay Suha
- Bozena Armanda
- Bratsberg Bjorn
- Bravo Silvina
- Brett Carole
- Brett Stephen
- Brett Stephen J.
- Briva Arturo
- Brizio Elisabetta
- Brizuela Patricia
- Broadhurst Phil
- Brown Wendy
- Browne Troy
- Bruel Cédric
- Bruhn Louise
- Brumwell Sarah
- Bruni Andrea
- Bruno Anna Vita
- Buckley Sarah
- Bull Rhian
- Bumbasirevic Vesna
- Buregeya Egide
- Burns Karen
- Butcher Rand
- Byers Heather
- Bösl Kathrin
- Cabral Dolly Mabel Bordon
- Cabral João
- Cabrita Paula
- Caddell Paul
- Caicedo Nestor
- Calamai Italo
- Calili Duygu Kayar
- Caliskan Gulbahar
- Calleja Pablo Lopez-Arcas
- Calpe Neus
- Calvino-Gunther Silvia
- Campanili Ticiane
- Campbell Elizabeth
- Campos Pierina Arias
- Campos-Perez Margarita
- Camputaro Luis
- Camsooksai Julie
- Canales Julieta
- Canete Fidelina
- Cani Alma
- Cano Anastasio Espejo
- Cao Deyan
- Cao Wenzhen
- Cao Ying
- Cao Zu Qing
- Capuzzi Fabio
- Cardenas Yenny
- Carey Annette
- Carney Dominic
- Carter Charlotte
- Casaioli Simona
- Castelain Vincent
- Castiglione Giacomo
- Cata Juan
- Cavaco Raquel
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- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
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- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
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- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 13/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study (Intensive Care Medicine, (2021), 47, 2, (160-169), 10.1007/s00134-020-06234-9)
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
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- Anne Marie Kodal
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- Armanda Bozena
- Armando Schmukler
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- Stefan Schaller
- Stefano Coremans
- Stella Soundoulounaki
- Stella Uba
- Stephan Graeser
- Stephanie Harris
- Stephen Brett
- Stephen M Pastores
- Stijn Van de Velde
- Styliani Bastani
- Styliani Kourelea
- Suha Bozbay
- Sun Lijuan
- Sun Zhiping
- Sundaresan Maiyalagan
- Sundaresan Maiyalagan
- Sundaresan Maiyalagan
- Sung Wai Ho
- Sunghoon Park
- Sunthiti Morakul
- Susana Ferreira
- Susana Pinto
- Susanna Hojden
- Susanne Fischer
- Suzana Bianchini
- Suzana Pečenković
- Suzanne Barrowcliffe
- Suzanne Bench
- Swagata Tripathy
- Swagotika Salo
- Sylvi Vullum
- Syragoula Tsikriki
- Sébastien Jochmans
- Sébastien Pili-Floury
- Taha Khaled
- Tai Sun Park
- Takoua Merhabene
- Talia Ben-Jacob
- Tamas Szakmany
- Tamas Vymazal
- Tanja Depuydt
- Tanja Goranovic
- Tao Zan
- Tara Clesi
- Tarek Dendane
- Tarja Tervo-Heikkinen
- Tatiana Patrichi
- Tatjana Beker
- Taís Pantaleao
- Teena Maguire
- Theogene Twagirumugabe
- Theogene Twagirumugabe
- Theonymfi Papavasilopoulou
- Thierry Dugernier
- Thomai Tholioti
- Thomas Dimski
- Thomas Leong
- Thomas Llewellym
- Tianfei Chen
- Ticiane Campanili
- Tien Meng Khoo
- Tim Chimunda
- Timothy Eng
- Tina Charlotte Bitsch Hansen
- Tina Damgaar Thomsen
- Tine Melgaard Frandsen
- Ting Han
- Tingting Li
- Tingting Yu
- Tobias Heinicke
- Tobias Odenthal
- Tobias Schulze
- Tom Dormans
- Tomas Jovaisa
- Tomas Jovaisa
- Tomas Vymazal
- Tomasz Torlinski
- Tomislav Mirkovic
- Tonia Onyeka
- Touraj Rastegar
- Treiza Trueman-Dawkins
- Trina Zhivotneva
- Troy Browne
- Turkay Akbas
- Ulf Guenther
- Ulla Kesti
- Ulla Sandberg
- Ulrica Mickelsson
- Ulrich Jaschinski
- Umeda Aya
- Una Gunter
- Uri Gorokhovatsky
- Uta Kolussi
- V Gusarov
- Vaarisan Ganeshalingam
- Vaibhav Bhargava
- Valentina Bendelari
- Valentina Di Gravio
- Vanda Seromenho
- Vanesa Mercado Telleria
- Vanesa Mercado Telleria
- Vanja Gievski
- Vanja Misic
- Vasileios Bekos
- Vasiliki Chantziara
- Vasilios Koulouras
- Vasilios Koulouras
- Veronica Curilen
- Veronika Kotanidi
- Vesna Bumbasirevic
- Vicent Salvà-Costa
- Victor Gonzalez
- Victoria Houghton
- Victoria Khoronenko
- Victoria Marriott
- Vilas Kushare
- Vincent Castelain
- Vincent Fraipont
- Vincianne Pleitinckx
- Virginie Souppart
- Virpi Lusenius
- Vishnu Das Sasidharan Nair
- Vitaly Gusarev
- Vitaly Gusarov
- Vitor Gomes
- Vitor Manuel Vaz Pinto
- Viveca Hamback Hellkvist
- Višnja Nesek Adam
- Vladimir Gurevich
- Vladimir Kulakov
- Vladislav Belskiy
- Volkan Inal
- Volodymyr Babych
- Vongayi Ogbeide
- W Nazaruddin W Hassan
- Walid Naija
- Walid Sellami
- Walter Swinnen
- Wan Nasrudin Wan Ismail
- Wang Zhijuan
- Wangari Waweru-Siika
- Wangari Waweru-Siika
- Wangyan Jin
- Wei Sun
- Wei Wang
- Wei Wei
- Wei Zhang
- Wei Zhang
- Weilian Yuan
- Weiwei Li
- Wenche Arntsen
- Wendy Brown
- Wendy Chaboyer
- Wendy Milner
- Wenjie Ju
- Wenmei Wang
- Wenmin Chen
- Wenwen Zhao
- Wenzhen Cao
- Wesal Ali Belkhair
- Willem Dieperink
- Windu Baskoro
- Won-Yeon Lee
- Wu Yuchen
- Xia Cui
- Xia Huang
- Xianhong Zheng
- Xianping Luo
- Xiao Fang Tian
- Xiao Xu
- XiaoChun Hu
- Xiaodi Liu
- Xiaofang Luo
- Xiaohan Li
- Xiaohan Li
- Xiaojun Wu
- Xiaoli Yan
- Xiaomin Wang
- Xiaoqiong Deng
- Xiaowu Bai
- Xiaoyan Chen
- Xiaoyan Chen
- Xiaoying Wu
- XiaoZhe Liu
- Ximena Villanueva
- Xingguo Li
- Xinhua Xia
- Xinhua Xia
- Xinjian Li
- Xinran Ding
- Xinxia Li
- Xinxia Li
- Xiuhua Fang
- Xiuhua Fang
- Xiujuan Xue
- XiuMei Liu
- Xiuying Yao
- Xiyan Wei
- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
- Yalım Dikmen
- Yalım Dikmen
- Yalim Dikmen
- Yan Gao
- Yan Li
- Yan Liu
- Yan Liu
- Yan Long
- Yan Wan
- Yan Wang
- Yan Xiao
- Yan Xie
- Yan Xu
- Yan Yan
- Yanfei Long
- Yang Lei
- Yang Liu
- Yang Wu
- Yang Xiaoyan
- Yanhong Di
- Yanhua Hao
- Yani Tian
- Yanlan Yao
- Yanling Shen
- Yanman Jian
- Yanmei Gu
- Yanming Ding
- Yann Le Guen
- Yanping Yang
- Yasser Mandourah
- Yenny Cardenas
- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
- Ying Wang
- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
The original version of this article unfortunately contained a mistake. The members of the ESICM Trials Group Collaborators were not shown in the article but only in the ESM. The full list of collaborators is shown below. The original article has been corrected