Inhibition Evaluation of 5-(4-(1H-pyrrol-1-yl)phenyl)-2-mercapto-1,3,4-oxadiazole for the Corrosion of Mild Steel in an Acidic Environment: Thermodynamic and DFT Aspects

In this investigation, an oxadiazole namely 5-(4-(1H-pyrrol-1-yl)phenyl)-2-mercapto-1,3,4-oxadiazole (PMO), was synthesized and explored as an inhibitor against the corrosion  of mild steel in 1.0 M hydrochloric acid environment at various solution temperature 303-333 K. gravimetric, and microscopic techniques, namely, weight loss (WL), and scanning electron microscopy (SEM), have been used to evaluate the inhibitive performance of the tested PMO. The results of the WL method displayed that the inhibition efficiency (%IE) was found to increase with the inhibitor concentration, while it reduced with increasing temperature. Furthermore, the WL results reveal that PMO inhibits corrosion display an IE of 95% at the highest concentration of 0.005 M. The SEM images of the mild steel surface coupon after adding PMO revealed a wide coverage of PMO molecules on the mild steel surface. Hence, the high inhibiting efficiency acquired by the tested inhibitor was explained by the strong adsorption of PMO molecules on the surface of mild steel. A protective layer has been constructed and it separating the mild steel surface from the hydrochloric acid solution, and such adsorption was found to obey Langmuir adsorption isotherm. Moreover, the thermodynamic parameters suggested that the adsorption nature of PMO molecules on the coupon surface was chemo-physisorption. Quantum chemical calculations were conducted by density functional theory (DFT) which help correlate the methodological findings with the theoretical investigations. The mechanisms of PMO molecules as corrosion inhibitor for mild steel surface in the corrosive environment was also discussed

Limitations of Prostate Biopsy in Detection of Cribriform and Intraductal Prostate Cancer

Funding Information: Acknowledgments: Rui M. Bernardino is supported by Fundacao para a Ciencia e a Tecnologia (2022.13386.BD). Publisher Copyright: © 2023 European Association of UrologyBackground: The presence of cribriform morphology and intraductal carcinoma (IDC) in prostate biopsies and radical prostatectomy specimens is an adverse prognostic feature that can be used to guide treatment decisions. Objective: To assess how accurately biopsies can detect cribriform morphology and IDC cancer by examining matched biopsy and prostatectomy samples. Design, setting, and participants: Patients who underwent radical prostatectomy at The Princess Margaret Cancer Centre between January 2015 and December 2022 and had cribriform morphology and/or IDC in the surgical specimen were included in the study. Outcome measurements and statistical analysis: We used detection sensitivity to evaluate the level of agreement between biopsy and prostatectomy samples regarding the presence of cribriform morphology and IDC. Results and limitations: Of the 287 men who underwent radical prostatectomy, 241 (84%) had cribriform morphology and 161 (56%) had IDC on final pathology. The sensitivity of prostate biopsy, using radical prostatectomy as the reference, was 42.4% (95% confidence interval [CI] 36–49%) for detection of cribriform morphology and 44.1% (95% CI 36–52%) for detection of IDC. The sensitivity of prostate biopsy for detection of either IDC or cribriform morphology was 52.5% (95% CI 47–58%). Among patients who underwent multiparametric magnetic resonance imaging–guided biopsies, the sensitivity was 54% (95% CI 39–68%) for detection of cribriform morphology and 37% (95% CI 19–58%) for detection of IDC. Conclusions: Biopsy has low sensitivity for detecting cribriform morphology and IDC. These limitations should be incorporated into clinical decision-making. Biomarkers for better detection of these histological patterns are needed. Patient summary: Prostate biopsy is not an accurate method for detecting two specific types of prostate cancer cells, called cribriform pattern and intraductal prostate cancer, which are associated with unfavorable prognosis.proofepub_ahead_of_prin

Doa-Doa Nabi & Keluarganya Yang Sudah Terbukti Mujarab

Kuamalkan sejumlah doa-doa yang sudah terbukti mujarab yang bisa mencakupi segala keperluan dan kesulitan. kucantumkan sumber-sumber doa itu, kusebut pula pengalaman orang-orang yang pernahmengamalkan dan mendapatkan manfaat dari doa-doa tersebut, supaya jd pendorongnuntuk mengamalkannya atas dasar akidah yang sempurna dan keimanan yang berhunjam dalam.342 hal : 22 x 15 c

Fiqih cinta kasih : rahasia kebahagiaan rumah tangga

Judul asli :Akhlak Al-Usrah Al-Muslimah Buhuuts wa Fatawaxxi, 335 p. : il.; 20 c

Fiqih cinta kasih : rahasia kebahagiaan rumah tangga/ Al-Musayyar

xxii, 335 hal.; 19 cm

Fiqih cinta kasih : rahasia kebahagiaan rumah tangga/ Al-Musayyar

xxii, 335 hal.; 19 cm

Islam Bicara Soal Seks, Percintaan, dan Rumah Tangga

xvi + 484 hlm. ; 19 cm