Effects of summary knowledge of results in motor skills acquisition

The effects of Summary Knowledge of Results (KR) were tested, using 30 volunteers and a positioning task in which a tennis ball had to be transported in 30 trials, following a specific sequence and with a target time of 3000 msec. Ten minutes after the acquisition phase, the transfer test was performed with 10 trials of different sequences and target times. The retention test took place 24 hours later with 10 trials of the same sequence and target time as the acquisition phase. In the transfer and retention tests, KR was not provided. The volunteers were randomly divided into three groups: G5 (KR every five trials); G3 (KR every three trials) and G100 (KR every trial). The results showed that G3 had a smaller absolute error than G100. However, G3 and G5 had a smaller constant error than G100. In general, the effects of G3 and G5 on motor skill acquisition could be caused by the lower KR frequency, which was 33% and 20% respectively.El efecto del conocimiento de los resultados (KR) resumen ha sido probado por 30 voluntarios en tarea de posicionamiento que requiere el transporte de una pelota de tenis en una secuencia específica con el tiempo objetivo de 3000 ms. en 30 ensayos. Diez minutos después de la fase de adquisición se jugó el test de transferencia con 10 ensayos con diferente secuencia y tempo objetivo. La retención se realizó la prueba 24 horas más tarde con la misma secuencia y tiempo objetivo fase de adquisición. En los testes de transferencia y retención de la CR no fue suministrado. Los voluntarios fueron divididos aleatoriamente en tres grupos: G5 (CR después de 5 ensayos); G3 (CR después de 3 ensayos) y G100 (CR en todos los ensayos). El resultado mostró que G3 tuvieron menor error absoluto que G100. Sin embargo, G3 y G5 se han registrado menor error constante que G100. En general, los efectos de G3 y G5 en la adquisición de las habilidades motoras pueden ser causados por la disminución de frecuencias CR, que fueron 33% y 20 %, respectivamente.O efeito do conhecimento de resultados (CR) sumário foi testado por 30 voluntários em uma tarefa de posicionamento a qual exigia o transporte de uma bola de tênis em uma sequência específica com tempo alvo de 3000 mseg. durante 30 tentativas. Dez minutos após a fase de aquisição foi desempenhado o teste de transferência com 10 tentativas com sequência e tempo alvo diferente. O teste de retenção foi realizado 24 horas mais tarde com a mesma sequência e tempo alvo da fase de aquisição. Nos testes de transferência e retenção o CR não foi fornecido. Os voluntários foram aleatoriamente divididos em três grupos: G5 (CR depois de 5 tentativas); G3 (CR depois de 3 tentativas) e G100 (CR em todas tentativas). O resultado mostrou que G3 apresentou menor erro absoluto que G100. Entretanto, G3 e G5 registraram menor erro constante que G100. Em geral, os efeitos de G3 e G5 sobre a aquisição de habilidades motoras podem ser causados pelas frequências reduzidas de CR, que foram de 33% e 20%, respectivamente

Sugarcane (Saccharum X officinarum): A Reference Study for the Regulation of Genetically Modified Cultivars in Brazil

Global interest in sugarcane has increased significantly in recent years due to its economic impact on sustainable energy production. Sugarcane breeding and better agronomic practices have contributed to a huge increase in sugarcane yield in the last 30 years. Additional increases in sugarcane yield are expected to result from the use of biotechnology tools in the near future. Genetically modified (GM) sugarcane that incorporates genes to increase resistance to biotic and abiotic stresses could play a major role in achieving this goal. However, to bring GM sugarcane to the market, it is necessary to follow a regulatory process that will evaluate the environmental and health impacts of this crop. The regulatory review process is usually accomplished through a comparison of the biology and composition of the GM cultivar and a non-GM counterpart. This review intends to provide information on non-GM sugarcane biology, genetics, breeding, agronomic management, processing, products and byproducts, as well as the current technologies used to develop GM sugarcane, with the aim of assisting regulators in the decision-making process regarding the commercial release of GM sugarcane cultivars

Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

Background: Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies. Methods: For this cross-sectional study, we assessed children and adolescents younger than 18 years with a clinical or genetic diagnosis of HeFH at the time of entry into the Familial Hypercholesterolaemia Studies Collaboration (FHSC) registry between Oct 1, 2015, and Jan 31, 2021. Data in the registry were collected from 55 regional or national registries in 48 countries. Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13·0 mmol/L were excluded from this study. Data were assessed overall and by WHO region, World Bank country income status, age, diagnostic criteria, and index-case status. The main outcome of this study was to assess current identification and management of children and adolescents with familial hypercholesterolaemia. Findings: Of 63 093 individuals in the FHSC registry, 11 848 (18·8%) were children or adolescents younger than 18 years with HeFH and were included in this study; 5756 (50·2%) of 11 476 included individuals were female and 5720 (49·8%) were male. Sex data were missing for 372 (3·1%) of 11 848 individuals. Median age at registry entry was 9·6 years (IQR 5·8-13·2). 10 099 (89·9%) of 11 235 included individuals had a final genetically confirmed diagnosis of familial hypercholesterolaemia and 1136 (10·1%) had a clinical diagnosis. Genetically confirmed diagnosis data or clinical diagnosis data were missing for 613 (5·2%) of 11 848 individuals. Genetic diagnosis was more common in children and adolescents from high-income countries (9427 [92·4%] of 10 202) than in children and adolescents from non-high-income countries (199 [48·0%] of 415). 3414 (31·6%) of 10 804 children or adolescents were index cases. Familial-hypercholesterolaemia-related physical signs, cardiovascular risk factors, and cardiovascular disease were uncommon, but were more common in non-high-income countries. 7557 (72·4%) of 10 428 included children or adolescents were not taking lipid-lowering medication (LLM) and had a median LDL-C of 5·00 mmol/L (IQR 4·05-6·08). Compared with genetic diagnosis, the use of unadapted clinical criteria intended for use in adults and reliant on more extreme phenotypes could result in 50-75% of children and adolescents with familial hypercholesterolaemia not being identified. Interpretation: Clinical characteristics observed in adults with familial hypercholesterolaemia are uncommon in children and adolescents with familial hypercholesterolaemia, hence detection in this age group relies on measurement of LDL-C and genetic confirmation. Where genetic testing is unavailable, increased availability and use of LDL-C measurements in the first few years of life could help reduce the current gap between prevalence and detection, enabling increased use of combination LLM to reach recommended LDL-C targets early in life

Effects of summary knowledge of results in motor skills acquisition

The effects of Summary Knowledge of Results (KR) were tested, using 30 volunteers and a positioning task in which a tennis ball had to be transported in 30 trials, following a specific sequence and with a target time of 3000 msec. Ten minutes after the acquisition phase, the transfer test was performed with 10 trials of different sequences and target times. The retention test took place 24 hours later with 10 trials of the same sequence and target time as the acquisition phase. In the transfer and retention tests, KR was not provided. The volunteers were randomly divided into three groups: G5 (KR every five trials); G3 (KR every three trials) and G100 (KR every trial). The results showed that G3 had a smaller absolute error than G100. However, G3 and G5 had a smaller constant error than G100. In general, the effects of G3 and G5 on motor skill acquisition could be caused by the lower KR frequency, which was 33% and 20% respectively.El efecto del conocimiento de los resultados (KR) resumen ha sido probado por 30 voluntarios en tarea de posicionamiento que requiere el transporte de una pelota de tenis en una secuencia específica con el tiempo objetivo de 3000 ms. en 30 ensayos. Diez minutos después de la fase de adquisición se jugó el test de transferencia con 10 ensayos con diferente secuencia y tempo objetivo. La retención se realizó la prueba 24 horas más tarde con la misma secuencia y tiempo objetivo fase de adquisición. En los testes de transferencia y retención de la CR no fue suministrado. Los voluntarios fueron divididos aleatoriamente en tres grupos: G5 (CR después de 5 ensayos); G3 (CR después de 3 ensayos) y G100 (CR en todos los ensayos). El resultado mostró que G3 tuvieron menor error absoluto que G100. Sin embargo, G3 y G5 se han registrado menor error constante que G100. En general, los efectos de G3 y G5 en la adquisición de las habilidades motoras pueden ser causados por la disminución de frecuencias CR, que fueron 33% y 20 %, respectivamente.O efeito do conhecimento de resultados (CR) sumário foi testado por 30 voluntários em uma tarefa de posicionamento a qual exigia o transporte de uma bola de tênis em uma sequência específica com tempo alvo de 3000 mseg. durante 30 tentativas. Dez minutos após a fase de aquisição foi desempenhado o teste de transferência com 10 tentativas com sequência e tempo alvo diferente. O teste de retenção foi realizado 24 horas mais tarde com a mesma sequência e tempo alvo da fase de aquisição. Nos testes de transferência e retenção o CR não foi fornecido. Os voluntários foram aleatoriamente divididos em três grupos: G5 (CR depois de 5 tentativas); G3 (CR depois de 3 tentativas) e G100 (CR em todas tentativas). O resultado mostrou que G3 apresentou menor erro absoluto que G100. Entretanto, G3 e G5 registraram menor erro constante que G100. Em geral, os efeitos de G3 e G5 sobre a aquisição de habilidades motoras podem ser causados pelas frequências reduzidas de CR, que foram de 33% e 20%, respectivamente

PCR-BASED DIAGNOSIS OF A CASE OF HERPETIC WHITLOW IN AN AIDS PATIENT

Herpetic infections are common complications in AIDS patients. The clinical features could be uncommon and antiviral chemotherapy is imperative. A rapid diagnosis could prevent incorrect approaches and treatment. The polymerase chain reaction is a rapid, specific and sensible method for DNA amplification and diagnosis of infectious diseases, especially viral diseases. This approach has some advantages compared with conventional diagnostic procedures. Recently we have reported a new PCR protocol to rapid diagnosis of herpetic infections with suppression of the DNA extraction step. In this paper we present a case of herpetic whitlow with rapid diagnosis by HSV-1 specific polymerase chain reaction using the referred protocol

Soil Erosion Satellite-Based Estimation in Cropland for Soil Conservation

Intensive cropland expansion for an increasing population has driven soil degradation worldwide. Modeling how agroecosystems respond to variations in soil attributes, relief and crop management dynamics can guide soil conservation. This research presents a new approach to evaluate soil loss by water erosion in cropland using the RUSLE model and Synthetic Soil Image (spectroscopy technique), which uses time series remotely sensed environmental, agricultural and anthropic variables, in the southeast region of São Paulo State, Brazil. The availability of the open-access satellite images of Tropical Rainfall Measuring Mission (TRMM) and Landsat satellite images provided ten years of rainfall data and 35 years of exposed soil surface. The bare soil surface and agricultural land use were extracted, and the multi-temporal rainfall erosivity was assessed. We predict soil maps’ attributes (texture and organic matter) through innovative soil spectroscopy techniques to assess the soil erodibility and soil loss tolerance. The erosivity, erodibility, and topography obtained by the Earth observations were adopted to estimate soil erosion in four scenarios of sugarcane (Saccharum spp.) residue coverage (0%, 50%, 75%, and 100%) in five years of the sugarcane cycle: the first year of sugarcane harvest and four subsequent harvesting years from 2013 to 2017. Soil loss tolerance means 4.3 Mg ha−1 exceeds the minimum rate in 40% of the region, resulting in a total soil loss of ~6 million Mg yr−1 under total coverage management (7 Mg ha−1). Our findings suggest that sugarcane straw production has not been sufficient to protect the soil loss against water erosion. Thus, straw removal is unfeasible unless alternative conservation practices are adopted, such as minimum soil tillage, contour lines, terracing and other techniques that favor increases in organic matter content and soil flocculating cations. This research also identifies a spatiotemporal erosion-prone area that requests an immediately sustainable land development guide to restore and rehabilitate the vulnerable ecosystem service. The high-resolution spatially distribution method provided can identify soil degradation-prone areas and the cropland expansion frequency. This information may guide farms and the policymakers for a better request of conservation practices according to site-specific management variation