Multi-Pion States in Lattice QCD and the Charged-Pion Condensate

The ground-state energies of systems containing up to twelve $\pi^+$'s in a spatial volume V ~ (2.5 fm)^3 are computed in dynamical, mixed-action lattice QCD at a lattice spacing of ~ 0.125 fm for four different values of the light quark masses. Clean signals are seen for each ground state, allowing for a precise extraction of both the $\pi^+\pi^+$ scattering length and $\pi^+\pi^+\pi^+$-interaction from a correlated analysis of systems containing different numbers of $\pi^+$'s. This extraction of the $\pi^+\pi^+$ scattering length is consistent with than that from the $\pi^+\pi^+$-system alone. The large number of systems studied here significantly strengthens the arguments presented in our earlier work and unambiguously demonstrates the presence of a low energy $\pi^+\pi^+\pi^+$-interaction. The equation of state of a $\pi^+$ gas is investigated using our numerical results and the density dependence of the isospin chemical potential for these systems agrees well with the theoretical expectations of leading order chiral perturbation theory. The chemical potential is found to receive a substantial contribution from the $\pi^+\pi^+\pi^+$-interaction at the lighter pion masses. An important technical aspect of this work is the demonstration of the necessity of performing propagator contractions in greater than double precision to extract the correct results.Comment: 38 pages, 20 figure

Thermoelectric properties of BiOCu1-xMxSe (M = Cd and Zn)

Doping of BiOCuSe at the copper site with divalent cadmium and zinc cations has been investigated. Analysis of the powder X-ray diffraction data indicates that the ZrCuSiAs structure of BiOCuSe is retained up to substitution levels of 10 and 5 at.% for Cd2+ and Zn2+, respectively. Substitution of monovalent Cu+ with divalent Cd2+ or Zn2+ leads to an increase in the magnitude of the electrical resistivity and the Seebeck coefficient. All synthesized materials behave as p-type semiconductors

Saponite Dissolution Experiments and Implications for Mars

Recent work suggests that the mineralogical sequence of the Murray formation at Gale crater may have resulted from diagenetic alteration after sedimentation, or deposition in a stratified lake with oxic surface and anoxic bottom waters. Fe-containing clay minerals are common both at Gale crater, and throughout the Noachian-aged terrains on Mars. These clay minerals are primarily ferric (Fe3+), and previous work suggests that these ferric clay minerals may result from alteration of ferrous (Fe2+) smectites that were oxidized after deposition. The detection of trioctahedral smectites at Gale crater by CheMin suggests Fe2+ smectite was also deposited during the early Hesperian. However, due to their sensitivity to oxygen, Fe2+ smectites are difficult to analyze on Earth and very few saponite dissolution rates exist in the literature. To the best of our knowledge, no experiments have measured the dissolution rates of ferrous saponites under oxidizing and reducing conditions. In order to better understand the characteristics of water-rock interaction at Gale crater, particularly the oxidation state, we report our results to date on ongoing syntheses of ferrous and magnesium saponites and dissolution experiments of natural saponite under ambient conditions. Future experiments will include the dissolution of synthetic ferric, ferrous, and magnesium saponites under oxidizing and anoxic conditions at a range of pH values

Performance of the User in the TDD NOMA Cellular Networks Enabling FFR

Improving the user performance and spectrum efficiency are urgent problems for 5G and beyond 5G (B5G) cellular networks to support high Quality of Services such as enhanced mobile broadband, ultra-reliable, and low latency communications. Together with Fractional Frequency Reuse (FFR), Time Division Duplex (TDD) and Non-Orthogonal Multi-Access (NOMA) are promising the potential solutions for these problems. While the related researches focus on the single or combination two of three techniques, this paper proposes a system that combination of all three techniques to improve the data rate on the uplink sub-band. Specifically, each couple of Cell-Center User (CCU) and Cell-Edge User (CEU) in a given cell, that is defined by the FFR technique, is allowed to transmit on the same sub-band by the meaning of power-domain NOMA technique. In addition, the TDD technique allow the sharing sub-band between the user and Base Station (BS). The analytical results in Nakagami-m fading and regular path loss model shows that achievable total data rate on the shared sub-band in the proposed system model is 18.2% and 125% higher than that in the regular one with TDD and NOMA, respectively. The data rate improvement of the proposed system model proves the feasibility of co-exits of these techniques in the B5G systems

A qualitative study on redefining normality in relatives of patients with advanced cancer

OBJECTIVE: To obtain insight into adaptation processes of redefining normality and its influencing factors in relatives of patients with advanced cancer.METHODS: An exploratory qualitative study among relatives of patients with advanced cancer was conducted. Participants were purposively recruited. Ten in-depth individual (relative only) and 16 dyad (relative and patient together) interviews were conducted, transcribed verbatim, and analyzed by means of thematic analysis, drawing on elements of grounded theory, combining both inductive and deductive elements.RESULTS: Two adaptation processes of (redefining) normality were identified: assimilation and accommodation. The latter was found to be the main way of adapting to new events. Assimilative coping strategies entailed "continuing to do the same activities as done before the disease," "difficulty accepting the situation," "avoiding to think about the disease," and "living in the short term." Accommodative strategies involved "arranging practical matters," "thinking about the future," "doing what is feasible," "engaging in new activities," "accepting the situation," "seeking distraction," "living in the short term," and "focusing on what truly matters in life." The interplay between the diagnosis and treatment of cancer, a deteriorating disease status, and the accompanying uncertainty about the future was of influence on the relatives' coping strategies.CONCLUSION: When the new situation is too divergent to assimilate, accommodation may be necessary for relatives to cope with the growing complexity of the consequences of their loved one's illness. Accommodative coping then involves accepting the changing reality and actively making the necessary adjustments to build resilience and cope with the new circumstances.</p

A qualitative study on redefining normality in relatives of patients with advanced cancer

OBJECTIVE: To obtain insight into adaptation processes of redefining normality and its influencing factors in relatives of patients with advanced cancer.METHODS: An exploratory qualitative study among relatives of patients with advanced cancer was conducted. Participants were purposively recruited. Ten in-depth individual (relative only) and 16 dyad (relative and patient together) interviews were conducted, transcribed verbatim, and analyzed by means of thematic analysis, drawing on elements of grounded theory, combining both inductive and deductive elements.RESULTS: Two adaptation processes of (redefining) normality were identified: assimilation and accommodation. The latter was found to be the main way of adapting to new events. Assimilative coping strategies entailed "continuing to do the same activities as done before the disease," "difficulty accepting the situation," "avoiding to think about the disease," and "living in the short term." Accommodative strategies involved "arranging practical matters," "thinking about the future," "doing what is feasible," "engaging in new activities," "accepting the situation," "seeking distraction," "living in the short term," and "focusing on what truly matters in life." The interplay between the diagnosis and treatment of cancer, a deteriorating disease status, and the accompanying uncertainty about the future was of influence on the relatives' coping strategies.CONCLUSION: When the new situation is too divergent to assimilate, accommodation may be necessary for relatives to cope with the growing complexity of the consequences of their loved one's illness. Accommodative coping then involves accepting the changing reality and actively making the necessary adjustments to build resilience and cope with the new circumstances.</p

Neptune Trojans and Plutinos: colors, sizes, dynamics, and their possible collisions

Neptune Trojans and Plutinos are two subpopulations of trans-Neptunian objects located in the 1:1 and the 3:2 mean motion resonances with Neptune, respectively, and therefore protected from close encounters with the planet. However, the orbits of these two kinds of objects may cross very often, allowing a higher collisional rate between them than with other kinds of trans-Neptunian objects, and a consequent size distribution modification of the two subpopulations. Observational colors and absolute magnitudes of Neptune Trojans and Plutinos show that i) there are no intrinsically bright (large) Plutinos at small inclinations, ii) there is an apparent excess of blue and intrinsically faint (small) Plutinos, and iii) Neptune Trojans possess the same blue colors as Plutinos within the same (estimated) size range do. For the present subpopulations we analyzed the most favorable conditions for close encounters/collisions and address any link there could be between those encounters and the sizes and/or colors of Plutinos and Neptune Trojans. We also performed a simultaneous numerical simulation of the outer Solar System over 1 Gyr for all these bodies in order to estimate their collisional rate. We conclude that orbital overlap between Neptune Trojans and Plutinos is favored for Plutinos with large libration amplitudes, high eccentricities, and small inclinations. Additionally, with the assumption that the collisions can be disruptive creating smaller objects not necessarily with similar colors, the present high concentration of small Plutinos with small inclinations can thus be a consequence of a collisional interaction with Neptune Trojans and such hypothesis should be further analyzed.Comment: 15 pages, 9 figures, 6 tables, accepted for publication in A&

Machine Learning Outperforms Regression Analysis to Predict Next-Season Major League Baseball Player Injuries: Epidemiology and Validation of 13,982 Player-Years From Performance and Injury Profile Trends, 2000-2017

Background: Machine learning (ML) allows for the development of a predictive algorithm capable of imbibing historical data on a Major League Baseball (MLB) player to accurately project the player\u27s future availability. Purpose: To determine the validity of an ML model in predicting the next-season injury risk and anatomic injury location for both position players and pitchers in the MLB. Study Design: Descriptive epidemiology study. Methods: Using 4 online baseball databases, we compiled MLB player data, including age, performance metrics, and injury history. A total of 84 ML algorithms were developed. The output of each algorithm reported whether the player would sustain an injury the following season as well as the injury\u27s anatomic site. The area under the receiver operating characteristic curve (AUC) primarily determined validation. Results: Player data were generated from 1931 position players and 1245 pitchers, with a mean follow-up of 4.40 years (13,982 player-years) between the years of 2000 and 2017. Injured players spent a total of 108,656 days on the disabled list, with a mean of 34.21 total days per player. The mean AUC for predicting next-season injuries was 0.76 among position players and 0.65 among pitchers using the top 3 ensemble classification. Back injuries had the highest AUC among both position players and pitchers, at 0.73. Advanced ML models outperformed logistic regression in 13 of 14 cases. Conclusion: Advanced ML models generally outperformed logistic regression and demonstrated fair capability in predicting publicly reportable next-season injuries, including the anatomic region for position players, although not for pitchers

Multi-omics analysis reveals underlying host responses in pediatric respiratory syncytial virus pneumonia.

Respiratory syncytial virus (RSV) is an important pathogen causing pneumonia in children. Few studies have used multi-omics data to investigate the pathogenies of RSV pneumonia. Here, metabolomics was first used to identify potential biomarkers for RSV diagnosis. In the training cohort, serum from 36 healthy controls (HCs), 45 RSV pneumonia children, and 32 infectious disease controls (IDCs) were recruited. After analyses, six metabolites had potential diagnostic value. Using an independent cohort of 49 subjects, two biomarkers (neuromedin N and histidyl-proline diketopiperazine) were validated. Next, multi-omics analysis were applied to analyze the pathogenies of RSV pneumonia. Accumulation of collagen in the serum of RSVs indicated that RSV infection could lead to increased levels of soluble collage. Activation of the complement system and imbalance in lipid metabolism were also observed in RSV patients. The multi-omics analysis presented here revealed the signature protein and metabolite changes in serum caused by RSV infection

Barley plasma membrane intrinsic proteins (PIP aquaporins) as water and CO2 transporters

We identified barley aquaporins and demonstrated that one, HvPIP2;1, transports water and CO2. Regarding water homeostasis in plants, regulations of aquaporin expression were observed in many plants under several environmental stresses. Under salt stress, a number of plasma membrane-type aquaporins were down-regulated, which can prevent continuous dehydration resulting in cell death. The leaves of transgenic rice plants that expressed the largest amount of HvPIP2;1 showed a 40% increase in internal CO2 conductance compared with leaves of wild-type rice plants. The rate of CO2 assimilation also increased in the transgenic plants. The goal of our plant aquaporin research is to determine the key aquaporin species responsible for water and CO2 transport, and to improve plant water relations, stress tolerance, CO2 uptake or assimilation, and plant productivity via molecular breeding of aquaporins.</p