Macroporous materials: microfluidic fabrication, functionalization and applications

This article provides an up-to-date highly comprehensive overview (594 references) on the state of the art of the synthesis and design of macroporous materials using microfluidics and their applications in different fields

In situ photogalvanic acceleration of optofluidic kinetics: a new paradigm for advanced photocatalytic technologies

A multiscale-designed optofluidic reactor is demonstrated in this work, featuring an overall reaction rate constant of 1.32 s¯¹ for photocatalytic decolourization of methylene blue, which is an order of magnitude higher as compared to literature records. A novel performance-enhancement mechanism of microscale in situ photogalvanic acceleration was found to be the main reason for the superior optofluidic performance in the photocatalytic degradation of dyes as a model reaction

Quasiperiodic graphs: structural design, scaling and entropic properties

A novel class of graphs, here named quasiperiodic, are constructed via application of the Horizontal Visibility algorithm to the time series generated along the quasiperiodic route to chaos. We show how the hierarchy of mode-locked regions represented by the Farey tree is inherited by their associated graphs. We are able to establish, via Renormalization Group (RG) theory, the architecture of the quasiperiodic graphs produced by irrational winding numbers with pure periodic continued fraction. And finally, we demonstrate that the RG fixed-point degree distributions are recovered via optimization of a suitably defined graph entropy

Catalytic performance of carbonaceous materials in the esterification of succinic acid

Mesoporous carbonaceous materials have outstanding potential in many different applications such as adsorption, medicine and catalysis. We have recently reported the synthesis of a new form of mesoporous carbon, named Starbon((R)), obtained after low temperature carbonization of expanded starch. Such starch-derived mesoporous materials have several tunable properties including surface energies (ranging from hydrophilic to hydrophobic surfaces), which can be easily controlled by the degree of carbonization (from 200 to 700 degrees C). Due to the diversity of surface functional groups, Starbons((R)) can be easily chemically modified. Treatment of Starbon((R)) materials with sulfuric acid gave a solid acid that has promising properties as heterogeneous catalyst. Comparative catalytic studies with some other similar commercial carbonaceous materials such as DARCO((R)) and NORIT (R), as well as phosphorous-containing microporous carbons, are reported. (c) 2008 Elsevier B.V. All rights reserved

Valorisation of food residues: waste to wealth using green chemical technologies

Waste valorisation practises have attracted a significant amount of attention in recent years with the aim of managing waste in the most sustainable way. Food waste constitutes a largely under-exploited residue from which a variety of valuable chemicals can be derived. This contribution is aimed to set the scene for a further development and promotion of sustainable food waste valorisation practises to different end products using green chemical technologie

Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: in silico insights

There is an ongoing debate on the therapeutic potential of vaso-modulatory interventions against glioma invasion. Prominent vasculature-targeting therapies involve functional tumour-associated blood vessel deterioration and normalisation. The former aims at tumour infarction and nutrient deprivation medi- ated by vascular targeting agents that induce occlusion/collapse of tumour blood vessels. In contrast, the therapeutic intention of normalising the abnormal structure and function of tumour vascular net- works, e.g. via alleviating stress-induced vaso-occlusion, is to improve chemo-, immuno- and radiation therapy efficacy. Although both strategies have shown therapeutic potential, it remains unclear why they often fail to control glioma invasion into the surrounding healthy brain tissue. To shed light on this issue, we propose a mathematical model of glioma invasion focusing on the interplay between the mi- gration/proliferation dichotomy (Go-or-Grow) of glioma cells and modulations of the functional tumour vasculature. Vaso-modulatory interventions are modelled by varying the degree of vaso-occlusion. We discovered the existence of a critical cell proliferation/diffusion ratio that separates glioma invasion re- sponses to vaso-modulatory interventions into two distinct regimes. While for tumours, belonging to one regime, vascular modulations reduce the tumour front speed and increase the infiltration width, for those in the other regime the invasion speed increases and infiltration width decreases. We show how these in silico findings can be used to guide individualised approaches of vaso-modulatory treatment strategies and thereby improve success rates

High performance and small footprint spot size converters based on SWG metamaterial lenses

Spot size converters with high expansion ratio are required in a variety of situations. This is the case of non-focusing Silicon on Insulator (SOI) fiber-to-chip grating couplers, which typically require long adiabatic tapers (Ltaper >100μm) from the narrow single-mode waveguides (WSi-wire ~ 500nm) to the wide grating region (Wgrating ~ 15μm). Here, we explore the potential of subwavelength grating (SWG) dielectric metamaterials to implement integrated GRaded INdex (GRIN) lenses to expand the mode field. Our designs achieve the desired Beam Expansion (BE) with insertion losses below 1dB over a distance of only LBE ~ 17μm.Ministerio de Economía y Competitividad, Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (cofinanciado FEDER), (TEC2016-80718-R); Universidad de Málaga. Ministerio de Educación, Cultura y Deporte (MECD) (FPU16/06121); Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Using network science to analyze football passing networks: dynamics, space, time and the multilayer nature of the game

From the diversity of applications of Network Science, in this Opinion Paper we are concerned about its potential to analyze one of the most extended group sports: Football (soccer in U.S. terminology). As we will see, Network Science allows addressing different aspects of the team organization and performance not captured by classical analyses based on the performance of individual players. The reason behind relies on the complex nature of the game, which, paraphrasing the foundational paradigm of complexity sciences "can not be analyzed by looking at its components (i.e., players) individually but, on the contrary, considering the system as a whole" or, in the classical words of after-match interviews "it's not just me, it's the team".Comment: 7 pages, 1 figur

Enhancing urban autonomy : towards a new political project for cities.

As the 21st Century world assumes an increasingly urban landscape, the question of how definitive urban spaces are to be governed intensifies. At the heart of this debate lies a question about the degree and type of autonomy that towns and cities might have in shaping their economic, environmental, social and cultural geography. This paper aims to examine this question. Starting with the premise that the degree of autonomy any particular town or city has is inherently an empirical question – one which can only be conceptualised in relational terms vis-à-vis the distributed, networked and territorialised responsibilities and powers of the city and the nation-state and other zones of connection – we examine four different contexts where debates over autonomy have intensified in recent history (Brazil, UK, India and South Africa). Drawing on recent respective histories, we identify key elements and enablers in the making of urban autonomy: a characteristic that exists in a variety of guises and forms and creates a patchwork landscape of differentially powerful fragments. We reveal how, beyond its characteristic as a political ideal, autonomy surfaces as a practice that emerges from within specific sectors of particular societies and through their relationship with national and regional politics. Four alternative forms of urban autonomy are delineated: fragmented, coerced (or enclave), distributed and networked. We contend that the spatial templates for autonomy are not predetermined but can be enhanced in multiple different sites and forms of political space within the city. This enhancement appears essential for the integration and strengthening of capacities for sustainable and just forms of development throughout the urban

Engaging Rural Georgians in the Internal Revenue Service (IRS)-Mandated Community Health Needs Assessment

Background: On March 23, 2010, President Barack Obama signed the Patient Protection and Affordable Care Act (ACA) into law. The law became effective on March 23, 2012. The ACA stipulates that non-profit hospitals must demonstrate benefit to their communities through the process of community health needs assessments (CHNAs). Failure to comply with this law may result in loss of non-profit status or large fines. This report describes strategies for engaging rural communities in Internal Revenue Service (IRS)-mandated CHNAs. Methods: Public health practitioners from Georgia Southern University’s Jiann Ping Hsu College of Public Health collaborated with 18 rural, non-profit hospitals to complete community-specific CHNAs. Quantitative and qualitative data were gathered from primary and secondary data sources to provide a comprehensive assessment of the needs and the assets of each of the communities. Results: The project team assisted 18 rural, non-profit hospitals in assessing the needs of their communities. Technical reports provided to the hospitals described the issues discovered during the assessment. Hospitals were empowered to utilize the information to prioritize community- specific issues and to develop comprehensive plans for implementation. Conclusions: The CHNA process provides an opportunity to strengthen relationships between public health services and hospitals as well as between hospitals and the communities they serve. Hospitals need to identify and engage diverse sectors of the community in order to comprehensively assess the needs and assets of communities to address the social determinants of health and to reduce health inequities/disparities