Anatol Stefanowitsch: Corpus Linguistics. A Guide to the Methodology

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Employment during the pandemic COVID-19

Bakalářská práce se zabývá tématem zaměstnání v období pandemie COVID-19. V této problematice je vysvětleno několik základních pojmů jako je například práce z domova (homeoffice), kurzarbeit nebo podpůrný program "Antivirus". Jsou zde také uvedeny možnosti podpor a bonusů od státu. V práci byl zhotoven dotazníkový výzkum, který zkoumal znalost právě těchto pojmů u společnosti a jestli lidé využili nabízených příspěvků.ObhájenoThis Bachelor thesis is focusing on the unemployment during COVID-19 pandemic. There are several terms used to explain this problem such as homeoffice, kurzarbeit, or the "Antivirus" program. Additionally, there are options of support and bonuses that one can acquire from the state. The data were conducted through a questionnaire that explored the knowledge of these term and if people took advantage of the bonuses or benefits offered by the state

Marketingový mix firmy BEST, a.s.

Import 12/08/2008Prezenční545 - Institut ekonomiky a systémů řízeníNeuveden

Employment during the pandemic COVID-19

Bakalářská práce se zabývá tématem zaměstnání v období pandemie COVID-19. V této problematice je vysvětleno několik základních pojmů jako je například práce z domova (homeoffice), kurzarbeit nebo podpůrný program "Antivirus". Jsou zde také uvedeny možnosti podpor a bonusů od státu. V práci byl zhotoven dotazníkový výzkum, který zkoumal znalost právě těchto pojmů u společnosti a jestli lidé využili nabízených příspěvků.ObhájenoThis Bachelor thesis is focusing on the unemployment during COVID-19 pandemic. There are several terms used to explain this problem such as homeoffice, kurzarbeit, or the "Antivirus" program. Additionally, there are options of support and bonuses that one can acquire from the state. The data were conducted through a questionnaire that explored the knowledge of these term and if people took advantage of the bonuses or benefits offered by the state

Internal mammary node management in breast cancer. A review

Background. Internal mammary nodes visualized during sentinel node biopsy for breast cancer, remain an unresolved management issue. Further, both internal mammary node (IMN) radiotherapy and biopsy have attendant risks and hence should be used with caution. The purpose of this review is to highlight the available data and evidence. Methods and Results. A PubMed database from 1960 to 2012 using key words: internal mammary nodes, breast cancer radiotherapy planning, adjuvant radiotherapy, sentinel node biopsy in breast cancer and selected publications on the significance of internal mammary nodes in breast cancer treatment, published data and approaches used. We found 14513 relevant papers and we selected 30 that clearly investigated the management of internal mammary nodes during sentinel node search. We focused on the incidence of IMN metastasis (6 papers), risk factors associated with IMN drainage (9 reports), management of IMN and the impact on disease free and overall patient survival (15 papers). Conclusions. The evidence for breast cancer axillary nodes management is good but the data for other draining nodes such as internal mammary nodes are far less conclusive and further research is needed

Significance of resection margin as a risk factor for local control of early stage breast cancer

Breast conserving surgery combined with sentinel node biopsy represents currently the gold standard of treatment for early breast cancer. Although breast conserving surgery has been a widely accepted method for many years, there remain some highly controversial unresolved issues. The present analysis focused on the resection margin as one of the key factors for local control of the disease. Methods. Patient disease free survival and overall survival were collected from patients undergoing breast conserving surgery from 2004 to 2009 at the Department of Surgery Atlas hospital Zlin, Czech Republic. All patients with resection margin less then 5 mm were re-resected to achieve this clear resection margin of 5mm or more. Disease free survival (more specifically local relapse free survival, metastasis free survival and regional free survival) and overall survival were assessed. Results. The data on 330 patients were analyzed and 286/330 cases had complete follow-up. After a median follow-up of 70 months, 7 patients with isolated local relapse were identified (2.44%), 13 patients with distant metastasis without local relapse (4.54%) and 2 patients with relapse in the axilla without local relapse in the breast (0.7%). Conclusion. The final decision about the extent of resection margin remains controversial but based on the data on local control presented here it seems reasonable to increase the criteria for a clear resection margin to 5 mm

Omission of adjuvant radiation therapy in elderly patients with low risk breast cancer undergoing breast-conserving surgery - two center experience

Introduction. Breast cancer is, now often diagnosed in patients older than 70 years due to longer life expectancy. The usual treatment is mastectomy to obviate radiotherapy or breast-conserving surgery followed by radiotherapy. The aim of this study was to investigate the need for adjuvant radiotherapy in older patients and the consequences of omitting radiotherapy following conservative surgery.Methods. An extensive database search was made of patients who had been treated for breast cancer at the Department of Oncology, University Hospital Olomouc and the Atlas Hospital in Zlin (2004-2008). We identified 738 patients of whom 190 patients (25.7%) were older than 70 years of age. These were followed up for progression-free and overall survival. The cause of death was checked for breast cancer relapse.Results. In total only 9 patients undergoing breast saving surgery were ultimately identified. No patient had confirmed local recurrence during the follow up period: Two patients have died due to distant metastasis without local relapse and one patient has died for reasons other than breast cancer.Conclusion. Omitting radiotherapy after breast saving surgery provides an opportunity for women to undergo breast saving surgery and avoid 7 weeks of radiotherapy. This could significantly improve patient quality of life. In our of many years experience and from published randomized data, this procedure is safe for a select group of patients 70 years of age and older

Prognostic influence of internal mammary node drainage in patients with early-stage breast cancer

Background: The management of internal mammary nodes (IMNs) during multidisciplinary treatment of breast cancer has been debated for the last four decades without unequivocal conclusion. Patients and Methods: We retrospectively reviewed patients with breast cancer who underwent sentinel lymph node biopsy at our center from 2008 until 2012. IMN drainage was assessed as a potential risk factor for local and distant disease recurrence. Results: We identified 712 patients, with incidence of drainage to IMNs of 18.4%. No detrimental effect of the pattern of drainage to IMNs was found after a median follow-up of 58 months. A similar outcome was observed when drainage to IMNs was evaluated as a risk factor for patient survival. The potential risk factors for drainage to IMNs during sentinel lymph node biopsy were younger age (p=0.002) and tumor location in lower-outer, lower-inner, and upper-inner versus upper-outer quadrant (p<0.0001). Conclusion: The drainage to IMNs is unlikely to have a detrimental effect on patient outcome.[LO1304