855 research outputs found
Nonstationary Stochastic Simulation of Strong Ground-Motion Time Histories : Application to the Japanese Database
For earthquake-resistant design, engineering seismologists employ
time-history analysis for nonlinear simulations. The nonstationary stochastic
method previously developed by Pousse et al. (2006) has been updated. This
method has the advantage of being both simple, fast and taking into account the
basic concepts of seismology (Brune's source, realistic time envelope function,
nonstationarity and ground-motion variability). Time-domain simulations are
derived from the signal spectrogram and depend on few ground-motion parameters:
Arias intensity, significant relative duration and central frequency. These
indicators are obtained from empirical attenuation equations that relate them
to the magnitude of the event, the source-receiver distance, and the site
conditions. We improve the nonstationary stochastic method by using new
functional forms (new surface rock dataset, analysis of both intra-event and
inter-event residuals, consideration of the scaling relations and VS30), by
assessing the central frequency with S-transform and by better considering the
stress drop variability.Comment: 10 pages; 15th World Conference on Earthquake Engineering, Lisbon :
Portugal (2012
A set of Eurocode 8-compatible synthetic time-series as input to dynamic analysis
International audienceNon-linear dynamic analysis of existing or planned structures often requires the use of accelerograms that match a target design spectrum. Here, our main concern is to generate a set of motions with a good level of fit to the Eurocode 8 (EC8) design spectra for France. Synthetic time series are generated by means of a non-stationary stochastic method. To calibrate the distributions of various strong-motion parameters, we first select a reference set of accelerograms for a type B site category from the PEER Ground-Motion Database, which are then adjusted to the target spectrum through wavelet addition. Finally, we analyse non-linear seismic responses of a soil column including pore pressure effects and ductile structures using these records, revealing considerable variability despite the similarities in terms of spectral acceleration
Self-sustained spin-polarized current oscillations in multiquantum well structures
Nonlinear transport through diluted magnetic semiconductor nanostructures is investigated. We have considered a II–VI multiquantum well nanostructure whose wells are selectively doped with Mn. The response to a dc voltage bias may be either a stationary or an oscillatory current. We have studied the transition from stationary to time-dependent current as a function of the doping density and the number of quantum wells. Analysis and numerical solution of a nonlinear spin transport model shows that the current in a structure without magnetic impurities is stationary, whereas current oscillations may appear if at least one well contains magnetic impurities. For long structures having two wells with magnetic impurities, a detailed analysis of nucleation of charge dipole domains shows that self-sustained current oscillations are caused by repeated triggering of dipole domains at the magnetic wells and motion towards the collector. Depending on the location of the magnetic wells and the voltage, dipole domains may be triggered at both wells or at only one. In the latter case, the well closer to the collector may inhibit domain motion between the first and the second well inside the structure. Our study could allow design of oscillatory spin-polarized current injectors
STRONG SEISMIC MOTIONS ESTIMATED FROM A ONE DIRECTION-THREE COMPONENTS ("1D-3C") APPROACH, APPLICATION TO THE CITY OF ROME, ITALY
International audienceStrong seismic motions in soils generally lead to both a stiffness reduction and an increase of the energy dissipation in the surficial layers. In order to study such phenomena, several nonlinear constitutive models were proposed and were generally implemented for 1D soil columns. However, one of the main difficulties of complex rheologies is the large number of parameters needed to describe the model. In this sense, the multi-surface cyclic plasticity approach, developed by Iwan in 1967 but linked to Prandtl or Preisach theoretical work, is an interesting choice: the only data needed is the modulus reduction curve. Past studies have generally implemented such models for one-directional shear wave propagation in a "1D" soil column considering one motion component only ("1C"). Conversely, this work aims at studying strong motion amplification by considering seismic wave propagation in a "1D" soil column accounting for the influence of the 3D loading path on the nonlinear behavior of each soil layer. In the "1D-3C" approach, the three components (3C) of the outcrop motion are simultaneously propagated into a horizontally layered soil for which a three-dimensional constitutive relation is used (Finite Element Method). The alluvial site considered in this study corresponds to the Tiber River Valley, close to the historical centre of Rome (Italy). The computations are performed considering the waveforms referred as the 14th October 1997 Umbria-Marche earthquake, recorded on outcropping bedrock. Time histories and stress-strain hysteretic loops are computed all along the soil column. The octahedral stress, the strain-depth profiles and the transfer functions in acceleration (surface/outcrop spectral ratios) are estimated for the 1D-1C and the 1D-3C approaches, evidencing the influence of the three-dimensional loading path
Predominant-Period Site Classification for Response Spectra Prediction Equations in Italy
Abstract We propose a site classification scheme based on the predominant period of the site, as determined from the average horizontal-to-vertical (H/V) spectral ratios of ground motion. Our scheme extends Zhao et al. (2006) classifications by adding two classes, the most important of which is defined by flat H/V ratios with amplitudes less than 2. The proposed classification is investigated by using 5%-damped response spectra from Italian earthquake records. We select a dataset of 602 three-component analog and digital recordings from 120 earthquakes recorded at 214 seismic stations within an hypocentral distance of 200 km. Selected events are in the moment-magnitude range 4.0 ≤ Mw ≤ 6.8 and focal depths from a few kilometers to 46 km. We computed H/V ratios for these data and used these to classify each site into one of six classes. We then investigate the impact of this classification scheme on empirical ground-motion prediction equations by comparing its performance with that of the conventional rock/soil classification. Although the adopted approach results in a only a small reduction of overall standard deviation, the use of H/V spectral ratios in site classification does capture the signature of sites with flat frequency-response, well as deep and shallow soil profiles, characterized 2 C:\di_alessandro\site_classification_italy\final_version_of_paper\bssa-d-11-00084_di_alessandro_etal_final_revisions.doc by long-and short-period resonance, respectively; in addition, the classification scheme is relatively quick and inexpensive, which is an advantage over schemes based on measurements of shear-wave velocity
In-vivo, non-invasive detection of hyperglycemic states in animal models using mm-wave spectroscopy
Chronic or sustained hyperglycemia associated to diabetes mellitus leads to many medical complications, thus, it is necessary to track the evolution of patients for providing the adequate management of the disease that is required for the restoration of the carbohydrate metabolism to a normal state. In this paper, a novel monitoring approach based on mm-wave spectroscopy is comprehensively described and experimentally validated using living animal models as target. The measurement method has proved the possibility of non-invasive, in-vivo, detection of hyperglycemia associated conditions in different mouse models, making possible to clearly differentiate between several hyperglycemic states
PRENOLIN project. Results of the validation phase at sendai site
One of the objectives of the PRENOLIN project is the assessment of uncertainties associated with non-linear simulation of 1D site effects. An international benchmark is underway to test several numerical codes, including various non-linear soil constitutive models, to compute the non-linear seismic site response. The preliminary verification phase (i.e. comparison between numerical codes on simple, idealistic cases) is now followed by the validation phase, which compares predictions of such numerical estimations with actual strong motion data recorded from well-known sites. The benchmark presently involves 21 teams and 21 different non-linear computations. Extensive site characterization was performed at three sites of the Japanese KiK-net and PARI networks. This paper focuses on SENDAI site. The first results indicate that a careful analysis of the data for the lab measurement is required. The linear site response is overestimated while the non-linear effects are underestimated in the first iteration. According to these observations, a first set of recommendations for defining the non-linear soil parameters from lab measurements is proposed. PRENOLIN is part of two larger projects: SINAPS@, funded by the ANR (French National Research Agency) and SIGMA, funded by a consortium of nuclear operators (EDF, CEA, AREVA, ENL)
Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus.
Secreted protein Sonic hedgehog (Shh) ventralizes the neural tube by modulating the crucial balance between activating and repressing functions (GliA, GliR) of transcription factors Gli2 and Gli3. This balance—the Shh-Gli code—is species- and context-dependent and has been elucidated for the mouse spinal cord. The hypothalamus, a forebrain region regulating vital functions like homeostasis and hormone secretion, shows dynamic and intricate Shh expression as well as complex regional differentiation. Here we asked if particular combinations of Gli2 and Gli3 and of GliA and GliR functions contribute to the variety of hypothalamic regions, i.e. we wanted to clarify the hypothalamic version of the Shh-Gli code. Based on mouse mutant analysis, we show that: 1) hypothalamic regional heterogeneity is based in part on differentially stringent requirements for Gli2 or Gli3; 2) another source of diversity are differential requirements for Shh of neural vs non-neural origin; 3) Gli2 is indispensable for the specification of a medial progenitor domain generating several essential hypothalamic nuclei plus the pituitary and median eminence; 4) the suppression of Gli3R by neural and non-neural Shh is essential for hypothalamic specification. Finally, we have mapped our results on a recent model which considers the hypothalamus as a transverse region with alar and basal portions. Our data confirm the model and are explained by it
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
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