The influence of different prefermentative maceration processes and tartaric stabilization treatments on the color, cation content and other physico-chemical parameters of 'Băbească neagră' rosé wines

This study enhances knowledge in the physicochemical and color parameters of rosé wines produced by the prefermentative maceration of native Romanian 'Băbească neagră' (Vitis vinifera L.) grape varieties, both before and after tartaric stabilization treatments by the contact procedure in an MK70 ultra-refrigerator. One variety was prepared without maceration as a control sample and the other was subjected to the maceration process for one of the following seven periods of time: 3.5 hours, 7 hours, 10.5 hours, 14 hours, 17.5 hours, 21 hours and 24.5 hours. The prefermentative maceration process exerts a significant influence on the amount of volatile acids, on the pH, conductivity and the K+ cation. The phenolic compound content, the chromatic parameters and the cation content of wines are significantly influenced by both prefermentative maceration and tartaric stabilization. The multifactor ANOVA tests prove that there is an interaction for all parameters except for total acidity.

Анализ первичной инвалидности вследствие болезней органов дыхания в Республике Мoлдова

Institute of Phtysiopulmonology „Chiril Draganiuc”, Congresul III al Medicilor de Familie din Republica Moldova, 17–18 mai, 2012, Chişinău, Republica Moldova, Conferinţa Naţională „Maladii bronhoobstructive la copii”, consacrată profesorului universitar, doctor habilitat Victor Gheţeul, 27 aprilie, Chişinău, Republica MoldovaIntroducere. Bolile nespecifice ale aparatului respirator (BNAR) ocupă un loc de frunte în structura incidenţei, prevalenţei şi mortalităţii populaţiei adulte. Conform datelor cercetărilor ştiinţifice, răspăndirea BNAR este foarte variabilă şi oscilează între 7,2 şi 32,8% în diferite regiuni ale lumii. Invaliditatea primară, cauzată de bolile aparatului respirator, reflectând toate aspectele asistenţei pneumologice acordate, prezintă o problemă medico-socială serioasă. Pentru determinarea dizabilităţii s-a efectuat studierea indicilor dizabilităţii primare, cauzate de BNAR la persoanele în vârsta aptă de muncă în Republica Moldova în 2008-2011. Material şi metode. Datele raporturilor anuale oficiale de statistică pentru perioada indicată. Rezultate obţinute. În perioada cercetată se constată o tendinţă pozitivă de micşorare a numărului persoanelor cu dizabilităţi primar încadraţi (PDPÎ) din cauza BNAR de la 1,22 la 0,93 la 100 000 de populaţie adultă. În paralel, se atestă o micşorare a PDPÎ din cauza BNAR de la 2,4% la 2,05% în structura generală a maladiilor ( toate entităţile nosologice ) în invaliditatea primară. Concomitent se observă un nivel mai înalt al indicilor invalidităţii primare în rândurile populaţiei rurale (2008 – 66,1%, 2009 – 57,2%, 2010 – 62,3%, 2011 – 63,5%) comparativ cu populaţia urbană (2008 – 33,9%, 2009 – 42,8%, 2010 – 37,7%, 2011 – 36,5%). La analiza dinamicii PDPÎ pe categorii de vârstă se determină predominarea ponderii persoanelor de 40 de ani şi mai mult (2008 -87,8%, 2009 – 89,9%, 2010 – 88%, 2011 – 84,6% ). Repartizarea PDPÎ pe grade de invaliditate a constatat o schimbare a structurii: la păstrarea ponderii invalizilor de gradul I (0,4%), are loc scăderea numărului invalizilor de gradul II de la 61,7% în 2009 până la 58,4% în 2011 şi, respectiv, sporirea numărului invalizilor de gradul III de la 37,6% la 41,2%. Concluzii Tendinţa pozitivă de scădere a numărului PDPÎ din cauza BNAR cu o scădere concomitentă a ponderii invalizilor de gradul II şi sporirea numărului invalizilor de gradul III confirmă ameliorarea calităţii asistenţei medicale acordate acestei categorii de bolnavi şi lucrului de expertizare

Through complex evaluation bazed on ICF towards social inclusion

Consiliul Republican de Expertiză Medicală a Vitalităţii, IMSP Institutul de Ftiziopneumologie ,,Chiril Draganiuc”The methodology of expertise is based on the International Classification of Functioning, Disability and Health (ICF), adopted in 2001. Areas included in ICF are considered both health areas as well as health related areas, and are grouped in two main lists: (1) Structures and Functions of the body, and (2) Activities and Participation. The emphasis is done on the participation and on the preserved function, not on the incapacity and restrictions. ICF serves as the statistical tool, of research, clinical investigation, social politics and represents an adequate instrument in implementation of human rights at the international level. Metodologia expertizării contemporane se bazează pe Clasificarea internaţională a funcţionării dizabilităţii şi sănătăţii (CIF) adoptată în 2001. Domeniile incluse în CIF sunt considerate domenii de sănătate şi domenii asociate sănătăţii şi sunt grupate în două liste principale: (1) structuri şi funcţii ale corpului, şi (2) activităţi şi participare. Accentul se pune pe participare şi pe funcţie pastrată, nu pe incapacitate şi restricţii. CIF serveşte ca instrument statistic de cercetarea, de investigaţie clinică, de politică socială şi reprezintă un instrument adecvat de implemenate a drepturilor omului la nivel internaţional

Placement of oppositely charged aminoacids at a polypeptide termini determines the voltage-controlled braking of polymer transport through nanometer-scale pores

Protein and solid-state nanometer-scale pores are being developed for the detection, analysis, and manipulation of single molecules. In the simplest embodiment, the entry of a molecule into a nanopore causes a reduction in the latter's ionic conductance. The ionic current blockade depth and residence time have been shown to provide detailed information on the size, adsorbed charge, and other properties of molecules. Here we describe the use of the nanopore formed by Staphylococcus aureus alpha-hemolysin and polypeptides with oppositely charged segments at the N- and C-termini to increase both the polypeptide capture rate and mean residence time of them in the pore, regardless of the polarity of the applied electrostatic potential. The technique provides the means to improve the signal to noise of single molecule nanopore-based measurements

Influenţa negativă a temperaturii asupra compuşilor de aromă din vin

The aromatic profile of wine is offered by the variety of volatile chemical compounds, especially esters, alcohols, carboxylic acids and nitrogen compounds.These substancescan determine different aromas depending on concentration. One of the very important factors in forming aromasis the fermentation temperature whose which has anoptimal value between 15-17 °C. This study evaluated winessamples which were fermented without temperature control, reaching an average temperature inbetween 21-24°C. Following this experiment it was observed how the compounds that give floral and fruity aromas can give unwanted sensations in high concentrations. At the same time, several esters of the fatty acids were observe which give a heavy smell and cause the sensation of fats. The aromatic profile of the sample which was fermented at higher temperature is more affected, even becoming repulsive once the temperature is rising

Studiu privind influenţa diferitelor preparate levuriene folosite în tehnologia de producere a cidrului asupra compuşilor de aromă

Cider is an alcoholic beveragemade from the fermentedjuice of applesand whose production technology does not differ greatlyfrom that of wine.This study wants to identify the influence of selected yeast to aroma compounds from cider. The cider samples were obtained by 110L of apple juice after classic fermentation. It was divided into seven glass containers of 15 liters of juice and subjected to fermentation. It was used seven types of selected yeast: V1-Fermativ Blanc Aromatique Sodinal®, V2-Lalvin Rhone 2056 Yseo Lallemand®, V3-Maurivin AB®, V4-Yseo Cross Evolution Lallemand®, V5-Fermactive Thyol Sodinal®, V6-Afinity ECA5 Levure-Yeast®, V7-Fermactive RBR®.The primary fermentation lasted for two weeks at a constant temperature of 18 ° C. The secondary fermentation happened after bottling. The cider aroma compounds were analysed by gas chromatography. It should be noted that it is not possible to carry out the quantitative analysis of the flavor compounds, so that the areas of the peaks corresponding to the identified compounds were used. It has been studied how the area increases depending on the yeast strains used. The results show a high content of flavor compounds of the group of alcohols, esters and acidsin all seven variants. Of all seven variants of levurian preparations, it was noted in the experiment with a high number of aromatic compounds in V3-Maurivin AB®

Caracteristici organoleptice ale unor vinuri spumante experimentale

There are two main production processes for the quality sparkling wines: traditional and „charmate“methods. In the traditional procedure, the second alcoholic fermentation of the base wine is carried out in sealed bottles. Some of the most popular sparkling wines, such as Champagne and Cava, are produced by the traditional method. Sensory and organoleptic characteristics are one of the most important indicators of sparkling wine quality for the acceptability of a product by consumers. So, this research is focused on the study of the influence of different yeasts strains on the organoleptic profile of the experimental sparkling white wines produced by traditional method. Therefore, a Muscat Ottonel grape must was used and passed by a reverse osmosis process. The obtained permeate was mixed with a calculated amount of the concentrate to generate a must with a potential of 10.5% (v/v) alcohol, in order to obtain the base wine for the second fermentation. The obtained, stabilized, sparkling wine was analyzed for oenological parameters and to determine the organoleptic characteristics. Following the organoleptic analysis, the significant differences in the sensory profile for the analyzed wine samples were confirmed

The role of cardiovascular imaging for myocardial injury in hospitalized COVID-19 patients

This is a pre-copyedited, author-produced version of an article accepted for publication in European Heart Journal - Cardiovascular Imaging, following peer review. The version of record: Bernard Cosyns, Stijn Lochy, Maria Luiza Luchian, Alessia Gimelli, Gianluca Pontone, Sabine D Allard, Johan de Mey, Peter Rosseel, Marc Dweck, Steffen E Petersen, Thor Edvardsen, on behalf of the European Association of Cardiovascular Imaging (EACVI), The role of cardiovascular imaging for myocardial injury in hospitalized COVID-19 patients, European Heart Journal - Cardiovascular Imaging, Volume 21, Issue 7, July 2020, Pages 709–714, https://doi.org/10.1093/ehjci/jeaa136 is available online at: https://doi.org/10.1093/ehjci/jeaa13

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat