636 research outputs found
Achiral, Chiral, and Protein Separations with Molecular Micelles Using Chromatographic Techniques
In this dissertation, several chromatographic techniques were developed for separation of proteins as well as achiral and chiral compounds. Firstly, polyelectrolyte multilayer (PEM) coatings were used to separate chiral analytes and proteins of pharmaceutical and biomedical interests. Coating polymers used in PEM coatings are instrumental in analyte separation. Therefore, the effect of changing four different cationic polymers, (poly-L-lysine, poly-L-ornithine, poly-L-lysine-serine, and poly-L-glutamic acid-lysine) and three anionic polymers (sodium poly (N-undecanoyl-L-leucyl-alaninate) (poly-L-SULA), sodium poly (N-undecanoyl-L-leucyl-valinate) (poly-L-SULV) and sodium poly (undecylenic sulfate) (poly-SUS)) were investigated. The simultaneous effects of cationic polymer concentration, number of bilayers, temperature, applied voltage, and pH of the background electrolyte on the separation on these analytes were analyzed using a Box Behnken experimental design. In addition, the influence of NaCl on the column reproducibility was investigated. Secondly, mixed mode separation using a combination of micellar electrokinetic chromatography (MEKC) and PEM coatings was used for the separation of achiral and chiral analytes. In this study, it was observed that achiral and separations using MEKC and PEM coatings individually resulted in partial resolution of 8 very similar aryl ketones and 5 chiral compounds when the molecular micelles (sodium poly (N-undecanoyl-L-glycinate) (poly-SUG)) and poly-L-SULV were used. However, when mixed mode separation was introduced, baseline resolution was achieved for all analytes. In the last study of this dissertation, PEM coatings were constructed using molecular micelles in open tubular capillary electrochromatography (OT-CEC) and gradient elution moving boundary electrophoresis (GEMBE) for protein separations. In OT-CEC, proteins were detected using both ultra violet (UV) and laser induced fluorescence (LIF) detection, while only LIF detection was used with the GEMBE technique. The effects of bilayer number, type of molecular micelle as well as pH of the background electrolyte on the separation of 6 acidic proteins were analyzed using ultra violet (UV) detection in OT-CEC. In addition, internal diameter and the effective length of the capillary were studied to investigate their influence on protein separations with LIF detection. High resolution protein separations were achieved using PEM coatings, therefore, these conditions were also used for protein separations with the GEMBE technique
Incorporating Students’ Perceived Needs and Interests in the Planning and Implementation of Lesson Plans
This paper examines and discusses the effects of integrating students’ perceived needs and interests in the planning and implementation of lessons plans to their attitudes towards English and their self-evaluations in the four skills and grammaring. The lesson plans were based on the prototypes developed by the Bureau of Secondary Education of the Department of Education in the Philippines. It particularly deals with students’ attitudes towards English and their self-evaluations in the four skills and grammaring and investigates the correlation between attitudes, the four skills, and grammaring
Propuesta de un programa para la capacitación docente con base en la didáctica
El presente trabajo consiste en elaborar una propuesta para la CREACIÓN DE UN PROGRAMA DE CAPACITACIÓN DOCENTE, CON BASE EN LA DIDÁCTICA, con el objeto de preparar al docente del ICHE para que profundice en su labor, creando un espacio para la reflexión de temas inherentes a mejorar su práctica educativa, puesto que hasta ahora, con excepciones, ha venido ejerciendo la docencia en base a su propia experiencia.
Este programa fundamenta la necesidad de su implementación a partir de un diagnóstico a los profesores y directivos de la Institución, en donde se determinó el nivel de necesidades de capacitación en los aspectos de la didáctica en general.
De acuerdo al diagnóstico de necesidades realizado, EL PROGRAMA DE CAPACITACIÓN DOCENTE CON BASE EN LA DIDÁCTICA, toma en consideración tres núcleos de capacitación o superación. que son:
1. FUNDAMENTOS EPISTEMOLÓGICOS Y TEORÍAS DEL PROCESO DOCENTE EDUCATIVO.
2. DISEÑO CURRICULAR, MÉTODOS Y TÉCNICAS DEL PROCESO DOCENTE EDUCATIVO.
3. FORMACIÓN EN VALORES
Engaging Ethnic-Diverse Students: A Research Based on Culturally Responsive Teaching for Roma-Gypsy Students
[Abstract] Intercultural Education is a key feature in the development of inclusion strategies aimed at ethnically diverse students. Transformative approaches towards learning such as Culturally Responsive Teaching (CRT) are essential in order to answer the educative needs that arise due to the coexistence between ethnic minorities and mainstream society. Therefore, cultural and historical representation of these communities play an important role as gatekeepers in order to achieve positive results as far as inclusive education is concerned. This article explores research based on a case study carried out in a high school located in the North-West of Spain developing successful learning stories after implementing the CRT methodology within the teaching of English as a foreign language. For its development, this article examines the trajectory of education with Roma-Gypsy students and moves forward with previous studies that endorse the success of using this approach among ethnically diverse students for their inclusion within the educative system. Intercultural and Plurilingual Education is a key feature in the development of inclusion strategies aimed at ethnically diverse students. This article includes research based on a case study carried out in a high school located in the North-West of Spain. It is aimed at: 1. Engaging ethnically diverse students to become part of the mainstream classroom through the inclusion of their culture; 2. Improving their language skills and competencies in the learning of a foreign language; 3. Raising the attendance at schools of ethnically diverse students. To achieve these targets the Culturally Responsive Teaching (CRT) Methodology has been implemented. CRT is considered essential to answer the educative needs that arise due to the coexistence between ethnic minorities and conventional communities. After gathering and analyzing data, results show that: ethnically diverse students’ motivation has been increased; it also expanded their social skills among peers; they gained more visibility; and finally, both diverse and non-diverse learners improved their proficiency in the English language. The discussion section states that the use of CRT Methodology traditionally used with Afro-American and Native-American students is also relevant for the Roma-Gypsy students that took part in this study
Use of the Erector Spinae Plane Block for the Perioperative Pain Management of the Cardiac Surgical Patient: An Educational Module
ABSTRACT
Background: Regional anesthesia has been at the forefront of opioid-sparing anesthesia. It has been proven time and again to be an effective method of safely and effectively controlling pain throughout the surgical process. Cardiac surgery presents its challenges to performing regional techniques due to the excessive amount of anticoagulation required to perform this type of surgery. The thoracic erector spinae plane block is a promising technique that has been shown to provide adequate pain control and is a safe alternative in patients who are anticoagulated compared to other regional techniques.
Objectives: The purpose of this study is to increase anesthesia provider knowledge on the value of the use of the ESP block for cardiac surgery. A literature review including primary research studies addresses the PICO question: “In anticoagulated patients undergoing general anesthesia for cardiac surgery, are erector spinae plane blocks when compared to thoracic epidurals, thoracic paravertebral blocks, and traditional methods safer to use while providing adequate perioperative analgesia?” The literature review is utilized to deliver the educational structure to increase provider knowledge. The objective is to increase provider awareness to improve patient outcomes and satisfaction related to cardiac surgery.
Methodology: The primary methodology of the proposed project is to administer an online educational intervention to providers which focuses on the benefits of the ESP block for cardiac surgery. Pre- and post-assessment surveys will be used to measure the improvement of provider knowledge before and after the intervention. The likelihood of use and recommendation of the ESP block for cardiac surgery will also be assessed.
Results: There was an overall improvement in provider knowledge following the educational intervention. The likelihood of utilizing and recommending the ESP block improved overall as well.
Conclusions: The evidence shows that the thoracic ESP block is a promising safe and effective tool for patients undergoing cardiac surgery via sternotomy or thoracotomy compared to the thoracic epidural, thoracic paravertebral block, and traditional methods. More research must be conducted via randomized controlled trials to ensure its safety and effectiveness
Feminismo para hombres : campaña universitaria aplicando la narrativa transmedia para impulsar nuevas masculinidades con un sentido de identidad más humano
La tesis que se presenta por medio de este documento es una investigación de carácter interdisciplicar que desde los estudios de género y el campo de la comunicación social, responde al llamado del feminismo a promover nuevas masculinidades. Se identifica como raiz del problema el carácter social de la categorias de género tradicional, binario, relacional, que han causado vacíos identitarios en las personas, hombres y mujeres, que aún de manera consciente o insconsciente, dejan que su experiencia de vida esté definida por los roles de género. Se propone como producto la pre-producción de una campaña a favor de nuevas masculinidades que implementa las herramientas de la narrativa transmedia para crear un relato que recrea el contexto y el campus de la Pontificia Universidad Javeriana. La historia cobra vida por medio de unos personajes, tanto docentes como estudiantes, que se pronuncian acerca del movimiento, tanto a favor como en contra. El discurso cobra sentido a partir de la diferenciación entre identidad y género, el género segmenta, mientras que nuestra identidad es un balance entre la naturaleza humana que es a la vez femenina y masculina. Para acompañar la pre-producción de la campaña se presentan una serie de prototipos de los contenidos de la misma.The thesis hereby presented is of interdisciplinary nature since links both gender studies a social communications. The project is a response to the feminist calling to promote new masculinities. The thesis identifies as a root issue the fact that conventional gender norms are constructed in a social context that have been historically interpreted as traditional, binary and relational, which result in identity issues in men and women that choose, consciously or unconsciously, to define themselves and their social experience through this limiting outlook on life and human nature. This thesis goes further than just investigate the issue, and therefore proposes as an advertising product the pre-production and production of prototype content of a campaign that would take place in order to promote new masculinities in the context of the Pontificia Universidad Javeriana, implementing transmedia storytelling. The story takes life and form through a series of characters, both professors and students, that manifest an opinion on the subject con the campaign and the discussion of new masculinities; the result is a mix of people in favor, against, or somewhere in the middle. What comes to light with the campaign is the difference between identity and gender. Gender in a traditional and binary sense divides, while identity is more broad and more representative of our human nature that when in balance shows both feminine and masculine aspects.Comunicador (a) SocialPregrad
O influxo do nivel de renda nas viaxes turísticas. Comparativa entre dous barrios da cidade da Coruña
[Resumo]: Ao longo do presente traballo realizase unha análise comparativa entre as
características das viaxes turísticas realizadas en dous barrios antagónicos,
economicamente falando, da Coruña: Cidade Vella - O Parrote (CP 15001) e O
Ventorrillo - A Agra do Orzán (CP 15010), co obxectivo principal de determinar como
inflúe o nivel de renda nas viaxes turísticas.
De xeito previo estúdanse os barrios en cuestión: a súa demografía, historia,
características socioculturais, etc. é dicir, datos que poderían afectar nas decisións
acerca das viaxes. Os datos a comparar foron obtidos a través dunha enquisa en liña
de elaboración propia e contestada por persoas veciñas de ambos os dous barrios.
As principais variables a analizar son as seguintes: número de viaxes realizadas con
anterioridade e posterioridade á pandemia da covid-19, razóns polas que non se fixo
ningunha no caso de que así fose, frecuencia, destino escollido, motivacións, período
do ano, forma de organización, tipo de aloxamento e transporte escollidos e gasto
turístico desagregado en cada unha das partidas que o conforman.
Por medio dunha análise descritiva na que se comparan as porcentaxes e gráficos
resultantes obtense información de gran relevancia. Pese a isto, é preciso complementar
a análise anterior por medio dunha técnica estatística máis elaborada e concreta que
permitira analizar a relación entre dúas variables como é o caso das táboas de
continxencia e a proba khi-cadrado.
Os resultados de ditas probas amosaron que o nivel de renda das persoas ten impacto
nas decisións de viaxe: as persoas con maior capacidade económica teñen maior
propensión a viaxar e a facelo de maneira máis frecuente, por maior tempo, a destinos
máis afastados e aloxándose en establecementos de maior categoría. Esta información
é relevante para adaptar a oferta turística a cada perfil económico concreto.[Abstract]: Throughout the present work, a comparative analysis has been done between the
characteristics of the touristic trips made by two economically antagonistic
neighbourhoods in A Coruña: Old Town - O Parrote (CP 15001) and O Ventorrillo - A
Agra do Orzán (CP 15010), with the main objective of determining how the wealth level
influences the touristic trips.
First, the neighbourhoods previously mentioned were studied: their population, history,
socio-cultural characteristics, etc. in other words, data that might have an impact on
travel choices. The data for comparison was obtained through an original online survey
answered by residents of both neighbourhoods.
The main variables to be analysed are number of trips made before and after the covid19 pandemic, reasons that explain why in some cases were not made, frequency,
chosen destination, motivations, period of the year, method of organisation, type of
accommodation and transport chosen, and tourist expenses detailed in each of the items
that compose it.
A descriptive analysis that compares the resulting percentages and figures provides
highly relevant information. Despite this, it is necessary to complement the previous
analysis with a more elaborated and concrete statistical technique that allow the analysis
of the relationship between two variables like the continence rates and the khi-squared
test do.
The results of those tests showed that people's wealth level has an impact on their travel
decisions: people with a higher economic capability have a higher tendency to travel and
to do so more frequently, for a longer period, to more remote destinations and to stay in
higher category accomodation. This information is relevant to suit the tourist offer to
every specific economic profile.Traballo fin de grao (UDC.ECO). Ciencias empresariais. Curso 2022/202
Análise, deseño e implementación de modelos de aprendizaxe máquina: predición usando datos sensóricos de buques arrastreiros
[Resumo]
En Galicia, a pesca representa un sector de alta importancia a nivel socioeconómico. En concreto,
o eido da pesca de arrastre é unha das artes pesqueiras con máis peso. Con todo, os
patróns dos buques arrastreiros enfróntanse a certos riscos debido ao descoñecemento do
fondo mariño. A isto súmase un certo atraso tecnolóxico do propio sector.
Partindo da infraestrutura xa existente neste tipo de barcos, nesta proposta preténdese
deseñar unha posible solución a un dos problemas que máis perdas económicas xera: o enfangamento
do aparello. O obxectivo principal do proxecto é obter unha predición precoz
do estado do aparello para evitar este problema. Isto conseguirase mediante a aplicación de
técnicas de aprendizaxe máquina a datos sensóricos de buques arrastreiros. Aplícanse algoritmos
tales como a regresión lineal, os bosques aleatorios, e as máquinas de soporte vectorial
para obter modelos de predición.
Búscase ademais despregar os modelos obtidos nunha aplicación web que poida ser instalada
nas computadoras das embarcacións. Os resultados obtidos nos modelos foron adecuados
para este problema, pero ao ser este un estudo novidoso neste tema, non se puideron comparar
os resultados con outros traballos semellantes.[Abstract]
In Galicia, fishing represents a socioeconomic high impact sector. Particularly, trawl fishing
is one of the most important fishing techniques. Nonetheless, captains from trawling
ships face some risks as a result of the lack of knowledge of the marine bottom. Also, the
sector suffers some technological backwardness.
Starting from the current infrastructure in this kind of ships, in this proposal a possible
solution is designed for one of the problems that generates more economical losses: the mud
catch in the trawling rig. Tha main objective in this project is to obtain an early prediction
of the state of the trawling rig to avoid this problem. This will be achieved through the application
of machine learning techniques to sensory data from trawling vessels. Algorithms
like linear regression, random forests and support vector machines are used to obtain the
prediction models.
We also seek to deploy these models in a web application that can be installed in the
vessels computers. The obtained results were good for our data, but because this research is
unique in this field, it couldn’t be compared with similar works.Traballo fin de grao (UDC.FIC). Enxeñaría informática. Curso 2019/202
A Phantom-Sensation Based Paradigm for Continuous Vibrotactile Wrist Guidance in Two-Dimensional Space
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