20 research outputs found
On a parabolic strongly nonlinear problem on manifolds
In this work we will prove the existence uniqueness and asymptotic behavior of weak solutions for the system (*) involving the pseudo Laplacian operator and the condition on , where is part of the lateral boundary of the cylinder and is a given function defined on
An Ontological Approach to Inform HMI Designs for Minimizing Driver Distractions with ADAS
ADAS (Advanced Driver Assistance Systems) are in-vehicle systems designed to enhance driving
safety and efficiency as well as comfort for drivers in the driving process. Recent studies have
noticed that when Human Machine Interface (HMI) is not designed properly, an ADAS can cause
distraction which would affect its usage and even lead to safety issues. Current understanding of
these issues is limited to the context-dependent nature of such systems. This paper reports the
development of a holistic conceptualisation of how drivers interact with ADAS and how such
interaction could lead to potential distraction. This is done taking an ontological approach to
contextualise the potential distraction, driving tasks and user interactions centred on the use of
ADAS. Example scenarios are also given to demonstrate how the developed ontology can be used
to deduce rules for identifying distraction from ADAS and informing future designs
On a parabolic strongly nonlinear problem on manifolds
El libro de María Valero se propone realizar una aproximación crítica a la presencia de unidades fraseológicas en la gramática y en la lexicografía, tarea ardua y compleja que la autora lleva a cabo con sumo cuidado y competencia metodológica
Weak solutions for a strongly-coupled nonlinear system
In this paper the authors study the existence of local weak solutions of the strongly nonlinear system where is the pseudo-Laplacian operator and , , and are given functions
Nonlinear perturbations of the Kirchhoff equation
In this article we study the existence and uniqueness of local solutions
for the initial-boundary value problem for the Kirchhoff equation
\displaylines{
u'' - M(t,\|u(t)\|^{2})\Delta u + |u|^{\rho} =f \quad\text{in }
\Omega \times (0, T_0), \cr
u=0\quad\text{on }\Gamma_0 \times ]0, T_0[, \cr
\frac{\partial u}{\partial \nu} + \delta h(u')=0 \quad\text{on }
\Gamma_1 \times ]0, T_0[,
}
where is a bounded domain of with its boundary
constiting of two disjoint parts and ;
is a real number; is the exterior unit normal vector at
and are real functions defined in
and , respectively.
Our result is obtained using the Galerkin method with a special basis,
the Tartar argument, the compactness approach, and a Fixed-Point method
Genomic analyses reveal two distinct lineages of Corynebacterium ulcerans strains
Corynebacterium ulcerans is an important zoonotic pathogen which is causing diphtheria-like disease in humans globally. In this study, the genomes of three recently isolated C. ulcerans strains, 4940, 2590 and BR-AD 2649, respectively from an asymptomatic carrier, a patient with pharyngitis and a canine host, were sequenced to investigate their virulence potential. A comparative analysis was performed including the published genome sequences of 16 other C. ulcerans isolates. C. ulcerans strains belong to two lineages; 13 strains are grouped together in lineage 1, and six strains comprise lineage 2. Consistent with the zoonotic nature of C. ulcerans infections, isolates from both the human and canine hosts clustered in both the lineages. Most of the strains possessed spaDEF and spaBC gene clusters along with the virulence genes cpp, pld, cwlH, nanH, rpfI, tspA and vsp1. The gene encoding Shiga-like toxin was only present in one strain, and 11 strains carried the tox gene encoding the diphtheria-like toxin. However, none of strains 4940, 2590 and BR-AD 2649 carried any toxin genes. These strains varied in the number of prophages in their genomes, which suggests that they play an important role in introducing diversity in C. ulcerans. The pan-genomic analyses revealed a variation in the number of membrane-associated and secreted proteins that may contribute to the variation in pathogenicity among different strains. Keywords: Corynebacterium ulcerans, diphtheria, nontoxigenic, sore throat, toxigenic, vaccine, virulence, zoonoti