Anthropological study of the incinerations of the Tumular Necropolis of the Corral de Mola (Uncastillo, Zaragoza)

Se presenta el estudio antropológico realizado sobre los restos óseos procedentes de la incineración funeraria del túmulo 1 y 5 de esta necrópolis, excavada entre los años 1977 y 1979 y fechada entre mediados del siglo VII y mediados del siglo VI a. C. A partir de la identificación de los restos conservados y de su clasificación osteológica y antropológica, se considera que la cremación alcanzó una temperatura elevada y que en el túmulo 1 se enterraron dos individuos de sexo masculino. En el túmulo 5, debido a la escasa recuperación de restos óseos, sólo se ha podido identificar como posibilidad la incineración de un individuo adultoThe anthropological study on the bones remains from the funeral incineration of graves 1 and 5 of this necropolis, excavated between 1977 and 1979 and dated between the middle of the 7th century and the middle of the 6th century a. C. is presented. From the identification of the preserved remains and their osteological and anthropological classification, it is considered that the cremation reached a high temperature and that in the tumuli 1 two men were buried. In tumuli 5, due to the scarce recovery of bone remains, only the incineration of an adult individual has been identified as a possibilit

General expressions for the stress intensity factor of a one-point bend beam

The aim of this work is to find general expressions to determine the stress intensity factor of a one point bend beam like specimen, whether from the measurement of the applied load or the crack mouth opening displacement. The expressions, obtained by applying the superposition principle, involve the decomposition of the general case into three auxiliary problems. The solution of two of them (pure bending and three point bending) is well known, while the solution of the third (one point bending) is developed in the present work. The proposed expressions are compared to numerical results obtained by the finite element method and their accuracy is equal to or better than available expressions published elsewhere.Publicad

Determination of the dynamic stress intensity factor of a specimen under one-point bending from the measurement of the load-point displacement

6 pages.-- Issue title: "EURODYMAT 2006 - 8th International Conference on Mehanical and Physical Behaviour of Materials under Dynamic Loading" (Dijon, France, Sep 11-15, 2006).The use of dynamic one-point bending tests as an alternative to three-point bending tests allows fracture properties such as dynamic initiation fracture toughness to be obtained at high strain rate. To perform this kind of test, experimental devices based on modifications of the Hopkinson bar can be used. Several authors have been proposed simplified procedures to obtain the dynamic stress intensity factor, K_I(t), considering the specimen as a Timoshenko cracked beam subjected to a concentrated load at the central cross-section. The disadvantage of this procedure is that normally it is difficult to measure the force applied to the specimen in the above-mentioned tests. Here a simplified method is proposed for the calculation of K_I(t), based on an analysis of the behaviour of a Timoshenko cracked beam, knowing the displacement of the point of loading, which can be measured more accurately than the applied load. The results were compared with those of a finite element numerical simulation and good agreement was found.Publicad

FORT: una herramienta de regresión borrosa

El uso de las técnicas de regresión sobre las observaciones experimentales ha permitido el estudio de numerosos fenómenos en diversos campos de la ciencia, y muy especialmente en las ciencias sociales. Dichas técnicas requieren de un número suficiente de observaciones “precisas”, exactas y fiables. Sin embargo, no siempre es posible obtener el conjunto de observaciones necesario, o éstas contienen algún tipo de imperfección en los datos, debido a la imprecisión o vaguedad de los mismos. En cualquier caso, con suficientes datos o no, con imperfecciones o no, los modelos obtenidos deberían proveer de capacidades predictivas y descriptivas [JCr02]. Las actuales herramientas, o las más fácilmente accesibles, tienen limitado el uso de modelos y difícilmente usan las técnicas de la teoría de conjuntos borrosos. Se propone en este trabajo una herramienta abierta de regresión que admita el uso de cualquier modelo de curva independientemente de su naturaleza. Además, esta herramienta permitirá el uso de diferentes formas de borrosidad y por su diseño permitiría cualquier modelo propuesto por el usuario si éste prevee que éstos tienen características que sean suficientemente predictivas y descriptivas. Esta primera aproximación de una herramienta abierta de regresión se realiza un estudio sobre diferentes modelos paramétricos simbólicos, usados comúnmente en la práctica en disciplinas tan heterogéneas como pueden ser la Ingeniería del Software, la Economía o en cualquier campo en donde puedan aparecer imprecisiones en la información. [ABSTRACT] The use of regression techniques in experimental observations has led to the study of numerous phenomena in various fields of science, especially in social science. These techniques require a sufficient number of “precise”, exact and reliable observations. However, it is not always possible to obtain all the necessary group of observations or these have some failings, as a result of inexact or vague data. Nevertheless, having more or less data, with or without failings, the obtained paradigms should provide predictive and descriptive capacities. The current tools or those more accessible have limited paradigm application and hardly use the techniques relating the fuzzy sets theory. In this first approach to an open regression tool, a study has been carried out of the different parametric, symbolic paradigms, commonly used in the practice of such diverse disciplines as Software Engineering, Economy or any other field where information imprecision can appear

Search for Mutations in a Segment of the Exon 28 of the Human Von Willebrand Factor Gene. New Mutations, R1315C and R1341W, Associated with Type 2M and 2B Variants

[EN] von Willebrand Disease (vWD) is the most frequently inherited bleeding disorder in humans, and is caused by a qualitative and/or quantitative abnormality of the von Willebrand factor (vWF), A large number of defects that cause qualitative variants have been located in the Al domain of the vWF, which contains sites for interaction with platelet glycoprotein Ib (GPIb). We have developed a new approach to detect mutations based on Ddel digestion and single-strand conformation polymorphism analysis. A segment of 487 nucleotides, extending from intron 27 to codon 1368 of the pre-pro vWF was amplified from genomic DNA, The cleavage with Ddel yields two fragments of appropriate size for this kind of analysis and confirms that the gene, rather than the pseudogene, is being investigated, Six families with type 2B vWD: one type 2M vWD family, and one another type 2A vWD family were studied. After sequencing the fragments with an altered electrophoretic pattern, we found four mutations previously described-R1308C, V1316M, P1337L, and R1306W-in patients with 2B vWD, The last one arose de novo in the patient. In addition, two new candidate mutations were observed: R1315C and R1341W. The first one was associated to type 2M vWD, whereas the one second cosegregated with type 2B vWD. The fact that these new mutations were not found in 100 normal alleles screened further supports their causal relationship with the disease, These mutations, which induce either a gain or a loss of function, further show an important regulatory role of this region in the binding of vWF to GPIb and its implications in causing disease.We wish to thank J.M. Montoro for performing multimeric assays and R. Curats for his technical assistance.Casaña, P.; Martínez, F.; Espinós-Armero, CÁ.; Haya, S.; Lorenzo, JI.; Aznar, JA. (1998). Search for Mutations in a Segment of the Exon 28 of the Human Von Willebrand Factor Gene. New Mutations, R1315C and R1341W, Associated with Type 2M and 2B Variants. American Journal of Hematology. 59(1):57-63. https://doi.org/10.1002/(sici)1096-8652(199809)59:13.0.co;2-z576359

Q1311X: a novel nonsense mutation of putative ancient origin in the von Willebrand factor gene

[EN] Type 3 von Willebrand disease, a recessive autosomally inherited bleeding disorder, refers to complete deficiency of von Willebrand factor (VWF). The novel Q1311X mutation was detected in the homozygous state in four Spanish patients from two apparently unrelated families of gypsy origin. The lack of specific amplification of platelet VWF cDNA from two of the patients indicates reduced levels of mutated gene expression. The similar haplotype linked to mutated alleles suggests a common origin. On the basis of the two instabilities observed and the estimated mutation rate of the microsatellites of intron 40 of the VWF gene, we can estimate that this mutation could have arisen about 2300 years ago.We wish to thank J.M. Montoro and R. Curats for their technical assistance. This work was supported in part by F1S 99/0633.Casaña, P.; Martínez, F.; Haya, S.; Lorenzo, JI.; Espinós-Armero, CÁ.; Aznar, JA. (2000). Q1311X: a novel nonsense mutation of putative ancient origin in the von Willebrand factor gene. British Journal of Haematology. 111(2):552-555. https://doi.org/10.1046/j.1365-2141.2000.02410.x552555111

Rituales funerarios en el calcolítico de Abauntz. Un ejemplo de lesión con supervivencia

Se estudian los ritos funerarios y el ajuar que acompañaba a los enterrados en el nivel Calcolítico de la Cueva de Abauntz con especial hincapié en un resto craneal con lesión y supervivencia del individuo. Se interpretaría éste como una intervención con un claro interés curativo que se resolvió favorablemente para el paciente

Integral field spectroscopy of the central regions of 3C 120: Evidence of a past merging event

Optical integral field spectroscopy (IFS), combined with Hubble Space Telescope (HST ) WFPC imaging, was used to characterize the central regions of the Seyfert 1 radio galaxy 3C 120. We carried out the analysis of the data, deriving intensity maps of different emission lines and the continua at different wavelengths from the observed spectra. Applying a two-dimensional modeling to the HST images, we decoupled the nucleus and the host galaxy and analyzed the host morphology. The host is a highly distorted bulge-dominated galaxy, rich in substructures. We developed a new technique to model the IFS data extending the two-dimensional modeling (hereafter threedimensional modeling). Using this technique, we separated the Seyfert nucleus and the host galaxy spectra and derived a residual data cube with spectral and spatial information of the different structures in 3C 120. Three continuum-dominated structures (named A, B, and C) and three other extended emission-line regions (EELRs, named E1, E2, and E3) are found in 3C 120, which does not follow the general behavior of a bulge-dominated galaxy. We also found shells in the central kiloparsec that may be remnants of a past merging event in this galaxy. The origin of E1 is most probably due to the interaction of the radio jet of 3C 120 with the intergalactic medium (Axon et al. 1989; Sa´nchez et al. 2004a). Structures A, B, and the shell at the southeast of the nucleus seem to correspond to a larger morphological clumpy structure that may be a tidal tail, a consequence of the past merging event. We found a bright EELR (E2) in the innermost part of this tidal tail, nearby the nucleus, which shows a high ionization level. The kinematics of the E2 region and its connection to the tidal tail suggest that the tail has channeled gas from the outer regions to the cente

Clean optical spectrum of the radio jet of 3C 120

We present integral field spectroscopy (IFS) of the central region of 3C 120. We have modeled the nuclear and host galaxy three-dimensional spectra using techniques normally applied to imaging, decoupling both components and obtaining a residual data cube. Using this residual data cube, we detected the extended emission line region associated with the radio jet. We obtained, for the first time, a clean spectrum of this region and found compelling evidence of a jet-cloud interaction. The jet compresses and splits the gas cloud, which is ionized by the active galactic nucleus (AGN ) and/or by the strong local UV photon field generated by a shock process. We cannot confirm the detection of an extended emission line region associated with the counterjet reported by Axon and coworkers.This project is part of the Euro3D RTN on IFS, funded by the EC under contract HPRN-CT-2002-00305. The WHT is operated on the island of La Palma by the Isaac Newton Group in the Spanish Observatorio del Roque de los Muchachos of the IAC. This project has used images obtained from the HST archive, using the ESO archiving facilities. We would like to thank R. C. Walker, who has kindly provided us with the radio maps of 3C 120. We would like to thank the anonymous referee, who has helped us to improve the quality of this paper with his/her remarks

The “post-weanling’s conundrum”: exploring the impact of infant and child feeding practices on early mortality in the Bronze Age burial cave of Moro de Alins, north-eastern Iberia, through stable isotope analysis

Producción CientíficaThe relationship between infant and child feeding practices and early mortality is difficult to address in past societies. Here, stable carbon (δ13C) and nitrogen (δ15N) isotope measurements of bulk bone and sequential dentine samples of deciduous second and/or permanent first molars of four younger children, one older child, one late adolescent, and two young adults (n = 8) from Moro de Alins cave, north-eastern Iberia, are used to explore the potential impact of early-life nutrition on mortality in the Bronze Age. Isotope results are compatible with generally short exclusive breastfeeding and standard weaning periods compared to other pre-modern populations. However, there are differences in exclusive breastfeeding mean δ13C values and in Δ13C trophic shifts between exclusive breastfeeding and immediate post-weaning isotope values for those individuals who survived into adolescence and adulthood and those who did not. While the former seem to be consistent with trophic distances published for modern mother–infant pairs, the latter are above most of them. This may suggest that individuals who consumed similar foods to their mothers or suffered from less physiological stress during or after weaning had greater chances of survival during early childhood and beyond. Post-weaning seems to have been a particularly stressful period of life, where a number of instances of patterns of opposing isotopic covariance compatible with catabolic changes, often preceding death among non-survivors, are detected. This outcome shows the key role of nutritional and/or physiological status in early-life morbidity and mortality among partially and especially fully weaned children from pre-antibiotic, pre-vaccination, and poor sanitation contexts and proposes that adult survival is rooted in early life experiences, in keeping with the developmental origins of health and disease.This work was supported and funded by the British Academy under the Newton International Fellowship NF170854European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 790491Ministerio de Ciencia e Innovación under the project (HAR2015-65620-P)Publicación en abierto financiada por el Consorcio de Bibliotecas Universitarias de Castilla y León (BUCLE), con cargo al Programa Operativo 2014ES16RFOP009 FEDER 2014-2020 DE CASTILLA Y LEÓN, Actuación:20007-CL - Apoyo Consorcio BUCL