The tidally disturbed luminous compact blue galaxy Mkn 1087 and its surroundings

We present new broad-band optical and near-infrared CCD imaging together with deep optical intermediate-resolution spectroscopy of Mkn 1087 and its surrounding objects. We analyze the morphology and colors of the stellar populations of the brightest objects, some of them star-formation areas, as well as the kinematics, physical conditions and chemical composition of the ionized gas associated with them. Mkn 1087 does not host an Active Galactic Nucleus, but it could be a Luminous Compact Blue Galaxy. Although it was classified as a suspected Wolf-Rayet galaxy, we do not detect the spectral features of these sort of massive stars. Mkn 1087 shows morphological and kinematical features that can be explained assuming that it is in interaction with two nearby galaxies: the bright KPG 103a and a dwarf ($M_B\sim-18$) star-forming companion. We argue that this dwarf companion is not a tidal object but an external galaxy because of its low metallicity [12+log(O/H) = 8.24] with respect to the one derived for Mkn 1087 [12+log(O/H) = 8.57] and its kinematics. Some of the non-stellar objects surrounding Mkn 1087 are connected by bridges of matter with the main body, host star-formation events and show similar abundances despite their different angular distances. These facts, together their kinematics, suggest that they are tidal dwarf galaxies formed from material stripped from Mkn 1087. A bright star-forming region at the south of Mkn 1087 (knot #7) does not show indications of being a tidal galaxy or the product of a merging process as suggested in previous works. We argue that Mkn 1087 and its surroundings should be considered a group of galaxies.Comment: Accepted by A&A, 21 pages, 13 figures, 8 table

Le rôle de l’Oxygénation Extracorporelle par Membrane (ECMO) dans la réanimation cardio-pulmonaire

Rapport de stage présenté à la Faculté de médecine en vue de l'obtention du grade de Maître ès sciences appliquées (M.Sc.A.) en génie biomédical, option génie clinique.L’objectif de cette étude a été de regrouper et d’analyser la littérature scientifique ainsi que les rapports d’agences d’évaluation des technologies de la santé traitant de l’efficacité et de la sécurité de l’utilisation de l’Oxygénation Extracorporelle par Membrane (Extracorpreal Membrane Oxygenation [ECMO]) comme thérapie chez des patients adultes gravement malades (insuffisance cardiaque et insuffisance respiratoire) ainsi que de l’utilisation d’ECMO en tant qu’alternative aux techniques conventionnelles de réanimation cardiopulmonaire. Un aperçu du principe de fonctionnement de la technologie est présenté en plus d’un aperçu des indications, contre-indications, complications et recommandations pour son utilisation. Méthodes : des bases de données de littérature scientifique tels que Medline (via PubMed), The Cochrane Library, University of York Centre for Reviews and Dissemination (CRD) et les sites Internet du Comité d’Évaluation des Technologies de Santé (CEDIT), de l’Agence Canadienne des Médicaments et des Technologies de la Santé (ACMTS), de la Haute Autorité de Santé (HAS), du Health Improvement Scottland (HIS) et du National Institute for Health and Care Excellence (NICE) ont été consultés. La recherche a été limitée à des rapports d’évaluation des technologies de la santé, des revues systématiques, méta-analyses, revues et lignes directrices, publiés entre le 1er janvier 2005 et le 22 octobre 2015 en anglais ou français. Résultats : Huit articles ont été sélectionnés pour l’analyse de l’efficacité et de la sécurité d’ECMO pour traiter des maladies cardiaques ou respiratoires graves, mais potentiellement réversibles. D’autres articles, tels qu’articles de synthèse de l’intervention, recommandations d’organismes spécialisés dans le sujet, lignes directrices publiées comme recommandations, etc., ont été sélectionnés pour extraire l’information concernant les indications et contre-indications du traitement ainsi que les recommandations lors de l’utilisation de l’équipement. Conclusions : En général, les auteurs s’entendent pour dire que les données ii scientifiques disponibles ne sont pas assez fortes pour soutenir irréfutablement l’utilisation de l’ECMO dans les cas de complications respiratoires ou cardiaques. Les progrès que connaît la technologie, ainsi que les études en cours pourraient permettre de donner un avis concluant sur les avantages (ou l’absence d’avantages) de cette technologie par rapport aux techniques conventionnelles ainsi que de mieux comprendre les affections spécifiques pour lesquels elle serait le meilleur choix.The objective of this study was to collect and analyze scientific literature as well as reports from health technology assessment agencies regarding the effectiveness and safety of the use of Extracorporeal Membrane Oxygenation (ECMO) as a therapy for critically ill adult patients (cardiac failure and respiratory failure) as well as the use of ECMO as an alternative to conventional CPR techniques. An overview of the principle of operation of the technology is presented and so is an overview of the indications, counter-indications, complications and recommendations for its use. Methods: scientific literature databases such as Medline (via PubMed), The Cochrane Library, University of York Centre for Reviews and Dissemination (CRD) as well as Health Technology Assessment agencies’ websites (Comité d’Évaluation des Technologies de Santé (CEDIT), Agence Canadienne des Médicaments et des Technologies de la Santé (ACMTS), Haute Autorité de Santé (HAS), Health Improvement Scottland (HIS), National Institute for Health and Care Excellence (NICE)) sites were consulted. The search was limited to health technology assessment reports, systematic reviews, meta-analysis, reviews and clinical guidelines, published between January 1, 2005 and October 22, 2015 in English or French. iii Results: Eight articles were selected for the analysis of the effectiveness and safety of ECMO to treat critical but potentially reversible heart and lung conditions. Other articles, such as interventional overview articles, recommendations by specialized organizations, guidelines published as recommendations, etc., were also retained to extract information regarding the indications and counter-indications of the treatment as well as the recommendations during the use of the equipment. Conclusions: In general, the authors share the idea that the data available is not strong enough to sustain irrefutably the use of ECMO, being it in the case of respiratory complications or cardiac complications. The developments in the technology as well as ongoing studies could allow to give a conclusive point of view regarding the benefits (or absence of) of this technology compared to conventional techniques as well as to better understand the specific conditions for which it would be the best choice

Влияние солей тяжелых металлов на активность ферментов глиоксилатного цикла и митохондриальной сукцинатдегидрогеназы в прорастающих семенах сои

Исследовано влияние СоСl2 и СdСl2 на активность изоцитратлиазы, малатсинтазы и сукцинатдегидрогеназы в семядолях сои на ранних этапах прорастания. Показано, что СоСl2 активирует изоцитратлиазную активность на третьи сутки, а СdСl2 ингибирует активность этого фермента уже в первые сутки прорастания по сравнению с контролем. Активность малатсинтазы снижается на пятые сутки прорастания независимо от наличия солей металлов. Ионы металлов тормозят активность сукцинатдегидрогеназы к пятым суткам.The influence of CoCl2 and CdCl2 on the activity of isocitratlyase, malatsynthase and succinate dehydrogenase in the seedlobes at early stages of germination of soybean seeds was investigated. CoCl2 increased isocitratlyase activity at 3-d day and CdCl2 suppressed isocitratlyase activity at the 1-st day. Salt of metals has no influence on malatsynthase activity. CoCl2 and CdCl2 suppressed succinate dehydrogenase activity at 5-th day that may be caused by oxidative stress

Análisis de calidad en los procesos de reclutamiento y selección de personal en la empresa Bimbo Colombia S.A.S en la ciudad de Bogotá para el 2022.

El desarrollo de este proyecto tiene como objetivo encontrar estrategias que permitan realizar de manera efectiva y eficiente los procesos de selección de personal dentro de la organización, lo cual permitiría encontrar el candidato idóneo para cada puesto de trabajo y así no se genere rotación de personal, despidos y renuncias. El método que se utilizara en esta investigación es el cuantitativo de acuerdo con las necesidades del estudio que es evidenciar la cantidad de personas que ingresan ala empresas, cuantas se adaptan, cuantas renuncian y a cuantas personas se despiden por no cumplir con los requerimientos y funciones del cargo para el cual se contratan. Además, la investigación cuantitativa nos permite confirmar, medir y probar estrategias para el problema que se presenta actualmente en el proceso de reclutamiento y selección de personal en la organización. Para recolectar los datos necesarios se realizará mediante el método de la entrevista, observación y encuestas, los cuales permitirá analizar los datos positivos y negativos. En los resultados obtenidos de la encuesta se evidencio que a la hora de publicar las vacantes no es clara la información de los perfiles que se requieren en el momento lo cual no permite que el candidato pueda identificar si es apto o no para el puesto de trabajo, una falencia que se evidencia en el momento de realizar las entrevistas es que algunas preguntas no concuerdan con la vacante a la cual se está presentando el candidato. La mayoría de encuestados indican que la empresa cumple con las condiciones establecidas en el contrato laboral, además una parte fundamental en cualquier empresa es el clima laboral a lo que los encuestados indican que es bueno. Sin embargo se pueden mejorar en aspectos como salario, ambiente laboral y motivación. Con relación a lo anterior queda claro que se deben implementar estrategias que permitan una adecuado desarrollo del talento humano, las cuales serían definir previamente las vacantes y perfiles requeridos, diseñar las preguntas que se harán en la entrevista para recolectar la información necesaria para elegir el candidato acorde a la vacante, implementar el programa de incentivos, cumplir a cabalidad con las condiciones establecidas en el contrato laboral y mantener un buen ambiente laboral.The development of this project aims to find strategies that allow effective and efficient personnel selection processes within the organization, which would allow finding the right candidate for each job and thus not generating staff turnover. layoffs and resignations. The method that will be used in this research is quantitative according to the needs of the study, which is to show the number of people who enter the companies, how many adapt, how many resign and how many people are fired for not complying with the requirements and functions of the cargo for which they are contracted. In addition, quantitative research allows us to confirm, measure and test strategies for the problem that currently arises in the process of recruitment and selection of personnel in the organization. To collect the necessary data, it will be carried out through the method of interview, observation, and surveys, which will be able to analyze the positive and negative data. In the results obtained from the survey, it was evidenced that when posting vacancies, the information on the profiles that is required at the time is not clear, which does not allow the candidate to identify whether or not he is suitable for the job. , a shortcoming that is evident at the time of conducting the interviews is that some questions do not match the vacancy for which the candidate is applying. The majority of those surveyed indicate that the company complies with the conditions established in the labor contract, in addition, a fundamental part of any company is the work environment, to which the respondents indicate that it is good. However, they can be improved in aspects such as salary, work environment and motivation. In relation to the above, it is clear that strategies must be implemented that allow an adequate development of human talent, which would be to previously define the vacancies and required profiles, design the questions that will be asked in the interview to collect the necessary information to choose the candidate according to the vacancy, implement the incentive program, fully comply with the conditions established in the employment contract and maintain a good work environment

An Unusual Transmission Spectrum for the Sub-Saturn KELT-11b Suggestive of a Sub-Solar Water Abundance

We present an optical-to-infrared transmission spectrum of the inflated sub-Saturn KELT-11b measured with the Transiting Exoplanet Survey Satellite (TESS), the Hubble Space Telescope (HST) Wide Field Camera 3 G141 spectroscopic grism, and the Spitzer Space Telescope (Spitzer) at 3.6 $\mu$m, in addition to a Spitzer 4.5 $\mu$m secondary eclipse. The precise HST transmission spectrum notably reveals a low-amplitude water feature with an unusual shape. Based on free retrieval analyses with varying molecular abundances, we find strong evidence for water absorption. Depending on model assumptions, we also find tentative evidence for other absorbers (HCN, TiO, and AlO). The retrieved water abundance is generally $\lesssim 0.1\times$ solar (0.001--0.7$\times$ solar over a range of model assumptions), several orders of magnitude lower than expected from planet formation models based on the solar system metallicity trend. We also consider chemical equilibrium and self-consistent 1D radiative-convective equilibrium model fits and find they too prefer low metallicities ($[M/H] \lesssim -2$, consistent with the free retrieval results). However, all the retrievals should be interpreted with some caution since they either require additional absorbers that are far out of chemical equilibrium to explain the shape of the spectrum or are simply poor fits to the data. Finally, we find the Spitzer secondary eclipse is indicative of full heat redistribution from KELT-11b's dayside to nightside, assuming a clear dayside. These potentially unusual results for KELT-11b's composition are suggestive of new challenges on the horizon for atmosphere and formation models in the face of increasingly precise measurements of exoplanet spectra.Comment: Accepted to The Astronomical Journal. 31 pages, 20 figures, 7 table

Enteric Budesonide in Transplant and Native IgA Nephropathy: Real-World Clinical Practice

Budesonide; Transplant; NephropathyBudesonida; Trasplante; NefropatíaBudesonida; Trasplantament; Nefropati

Parenteral Nutrition: Current Use, Complications, and Nutrition Delivery in Critically Ill Patients

Background: Parenteral nutrition (PN) is needed to avoid the development of malnutrition when enteral nutrition (EN) is not possible. Our main aim was to assess the current use, complications, and nutrition delivery associated with PN administration in adult critically ill patients, especially when used early and as the initial route. We also assessed the differences between patients who received only PN and those in whom EN was initiated after PN (PN-EN). Methods: A multicenter (n = 37) prospective observational study was performed. Patient clinical characteristics, outcomes, and nutrition-related variables were recorded. Statistical differences between subgroups were analyzed accordingly. Results: From the entire population (n = 629), 186 (29.6%) patients received PN as initial nutrition therapy. Of these, 74 patients (11.7%) also received EN during their ICU stay (i.e., PNEN subgroup). PN was administered early (<48 h) in the majority of patients (75.3%; n = 140) and the mean caloric (19.94 +/- 6.72 Kcal/kg/day) and protein (1.01 +/- 0.41 g/kg/day) delivery was similar to other contemporary studies. PN showed similar nutritional delivery when compared with the enteral route. No significant complications were associated with the use of PN. Thirty-two patients (43.3%) presented with EN-related complications in the PN-EN subgroup but received a higher mean protein delivery (0.95 +/- 0.43 vs 1.17 +/- 0.36 g/kg/day; p = 0.03) compared with PN alone. Once adjusted for confounding factors, patients who received PN alone had a lower mean protein intake (hazard ratio (HR): 0.29; 95% confidence interval (CI): 0.18-0.47; p = 0.001), shorter ICU stay (HR: 0.96; 95% CI: 0.91-0.99; p = 0.008), and fewer days on mechanical ventilation (HR: 0.85; 95% CI: 0.81-0.89; p = 0.001) compared with the PN-EN subgroup. Conclusion: The parenteral route may be safe, even when administered early, and may provide adequate nutrition delivery. Additional EN, when possible, may optimize protein requirements, especially in more severe patients who received initial PN and are expected to have longer ICU stays. NCT Registry: 03634943

Massive star formation and tidal structures in HCG 31

We present new broad-band optical and near-infrared CCD imaging together with deep optical intermediate-resolution spectroscopy of the Hickson Compact Group 31. We analyze the morphology and colors of the stellar populations of the galaxies, as well as the kinematics, physical conditions and chemical composition of the ionized gas in order to get a more complete view on the origin and evolution of the system. We estimate the ages of the most recent star formation bursts of the system, finding an excellent consistency among the values obtained with different indicators and starburst models. We find that member F hosts the youngest starburst of the group, showing a substantial population of Wolf-Rayet stars. The chemical abundances are fairly similar in all the members of the group despite their very different absolute magnitudes. We argue that the use of traditional metallicity-luminosity relations based on the absolute $B$-magnitude is not appropriate for dwarf starburst galaxies, because their luminosity is dominated by the transient contribution of the starburst to the blue luminosity. We think that members E and F of the group are candidate tidal dwarf galaxies because of their high metallicity, their kinematics, and the absence of underlying old stellar populations. Finally, we propose that HCG~31 is suffering several almost simultaneous interaction processes. The most relevant of these processes are: (a) the merging of members A and C, that would have produced two optical tidal tails; and (b) a fly-by encounter between G and the A+C complex, that would have produced an \ion{H}{1} tidal tail from the stripping of the external gas of A+C, from which members F and E have originated.Comment: Accepted for publication in ApJS, 41 pages, 15 figures, 9 table

Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER)Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13-3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms