43 research outputs found
Conversion of furan over gallium and zinc promoted ZSM-5 : the effect of metal and acid sites
The addition of gallium or zinc to ZSM-5 increases the aromatic selectivity and decreases the olefin selectivity for furan conversion. Both the benzene and naphthalenes selectivities increase with small amounts of gallium or zinc addition. At 5 wt% metal loading this effect is more pronounced with zinc promoted ZSM-5 having about 25% higher benzene selectivity than the gallium promoted ZSM-5. Additionally, the decarbonylation and methane formation reactions were both increased by adding zinc or gallium to the catalyst. As zinc or gallium loading is increased, the amount of Br酶nsted acid sites decrease, while the quantity of Lewis acid sites increase. This effect was more pronounced with zinc, as a result of its greater effectiveness to exchange with protons at the Br酶nsted acid sites. The aromatic yield appears to correlate with this increase in Lewis acidity. The addition of zinc to ZSM-5 also altered the reaction chemistry occurring during the hydrolysis of furan, lowering propylene and increasing methane yields as zinc loading increased
Gesti贸n del Cambio en la Educaci贸n Superior:Adaptaci贸n de Estrategias y Autosostenibilidad
Change management in higher education is a key issue today due to the rapid evolution of technology and the demands of the labor market. The adaptation of strategies and self-sustainability are two essential factors to achieve effective and successful change management in Higher Education Institutions. In this article, the current literature on change management in higher education will be reviewed, identifying the main strategies used to adapt to changes and the importance of sustainability in change management. The challenges and obstacles faced by higher education institutions when implementing changes will be discussed and examples of good practices in change management in different contexts will be presented. Finally, recommendations for change management in higher education will be presented, focused on the adaptation of strategies and self-sustainability, with the aim of helping institutions develop fundraising programs, promoting research and innovation as potential income generators. In this way, HEIs would be preparing efficiently for future changes and ensuring the quality of education offered.La gesti贸n del cambio en la educaci贸n superior es un tema clave en la actualidad debido a la r谩pida evoluci贸n de la tecnolog铆a y las demandas del mercado laboral. La adaptaci贸n de estrategias y la autosostenibilidad, son dos factores esenciales para lograr una gesti贸n del cambio efectiva y exitosa en las Instituciones de Educaci贸n Superior. En este art铆culo, se revisar谩 la literatura actual sobre la gesti贸n del cambio en la educaci贸n superior, identificando las principales estrategias utilizadas para adaptarse a los cambios y la importancia de la autosostenibilidad en la gesti贸n del cambio. Se discutir谩n los desaf铆os y obst谩culos que enfrentan las instituciones de educaci贸n superior al implementar cambios y se presentar谩n ejemplos de buenas pr谩cticas en la gesti贸n del cambio en diferentes contextos.Finalmente, se presentar谩n recomendaciones para la gesti贸n del cambio en la educaci贸n superior, enfocadas en la adaptaci贸n de estrategias y la autosostenibilidad, con el objetivo de ayudar a las instituciones a desarrollar programas de captaci贸n de fondos, promover la investigaci贸n y la innovaci贸n como generadores potenciales de ingresos.De esta forma, las IES se estarian preparando eficientemente para los cambios futuros y asegurando la calidad de la educaci贸n ofrecida
Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis
Thyroid hormones (THs) are essential for embryonic brain development but the genetic mechanisms involved in the action of maternal THs (MTHs) are still largely unknown. As the basis for understanding the underlying genetic mechanisms of MTHs regulation we used an established zebrafish monocarboxylic acid transporter 8 (MCT8) knock-down model and characterised the transcriptome in 25hpf zebrafish embryos. Subsequent mapping of differentially expressed genes using Reactome pathway analysis together with in situ expression analysis and immunohistochemistry revealed the genetic networks and cells under MTHs regulation during zebrafish embryogenesis. We found 4,343 differentially expressed genes and the Reactome pathway analysis revealed that TH is involved in 1681 of these pathways. MTHs regulated the expression of core developmental pathways, such as NOTCH and WNT in a cell specific context. The cellular distribution of neural MTH-target genes demonstrated their cell specific action on neural stem cells and differentiated neuron classes. Taken together our data show that MTHs have a role in zebrafish neurogenesis and suggest they may be involved in cross talk between key pathways in neural development. Given that the observed MCT8 zebrafish knockdown phenotype resembles the symptoms in human patients with Allan-Herndon-Dudley syndrome our data open a window into understanding the genetics of this human congenital condition.Portuguese Fundacao para Ciencia e Tecnologia (FCT) [PTDC/EXPL/MARBIO/0430/2013]; CCMAR FCT Plurianual financing [UID/Multi/04326/2013]; FCT [SFRH/BD/111226/2015, SFRH/BD/108842/2015, SFRH/BPD/89889/2012]; FCT-IF Starting Grant [IF/01274/2014]info:eu-repo/semantics/publishedVersio
La vid silvestre en M茅xico. Actualidades y potencial
En ocho cap铆tulos se aborda el estado del arte de la vid silvestre en M茅xicoEl estudio de las especies vegetales nativas de M茅xico representa un reto que cada d铆a m谩s investigadores mexicanos asumen. Durante muchos a帽os, el apoyo a la investigaci贸n p煤blica ha sido m铆nimo; desde el punto de vista agron贸mico es insuficiente para avanzar a la velocidad que requiere nuestro pa铆s para afrontar problemas de producci贸n y distribuci贸n de alimentos. Por esa raz贸n, entre otras, me es grato presentar esta obra que compila parte de los trabajos de la Red de Vid Silvestre patrocinada por el Sistema Nacional de Recursos Fitogen茅ticos (sinarefi) dependiente de la sagarpa; trabajos apuntalados por investigadores que sin pertenecer a la red han colaborado en el estudio de las plantas del g茅nero Vitis. En este libro se muestra el potencial del pa铆s para aprovechar el recurso vid, empleado desde antes de la conquista espa帽ola por nativos mexicanos que conoc铆an sus bondades. Es necesario continuar el avance en el conocimiento de este recurso, por ello el presente libro pretende invitar a toda persona interesada en contribuir con el rescate y conservaci贸n de las vides mexicanas. Los autores y editores, as铆 como las instituciones en donde laboramos y aquellas que patrocinan estas investigaciones, esperamos se cumpla este objetivo y que el lector, alumno, profesor, investigador, p煤blico en general, disfrute esta lectura y, sobre todo, se interese en el recurso VitisSEP, SINAREFI, UAEME
Prediction of High-Grade Vesicoureteral Reflux after Pediatric Urinary Tract Infection: External Validation Study of Procalcitonin-Based Decision Rule
BACKGROUND: Predicting vesico-ureteral reflux (VUR) 653 at the time of the first urinary tract infection (UTI) would make it possible to restrict cystography to high-risk children. We previously derived the following clinical decision rule for that purpose: cystography should be performed in cases with ureteral dilation and a serum procalcitonin level 650.17 ng/mL, or without ureteral dilatation when the serum procalcitonin level 650.63 ng/mL. The rule yielded a 86% sensitivity with a 46% specificity. We aimed to test its reproducibility.
STUDY DESIGN: A secondary analysis of prospective series of children with a first UTI. The rule was applied, and predictive ability was calculated.
RESULTS: The study included 413 patients (157 boys, VUR 653 in 11%) from eight centers in five countries. The rule offered a 46% specificity (95% CI, 41-52), not different from the one in the derivation study. However, the sensitivity significantly decreased to 64% (95%CI, 50-76), leading to a difference of 20% (95%CI, 17-36). In all, 16 (34%) patients among the 47 with VUR 653 were misdiagnosed by the rule. This lack of reproducibility might result primarily from a difference between derivation and validation populations regarding inflammatory parameters (CRP, PCT); the validation set samples may have been collected earlier than for the derivation one.
CONCLUSIONS: The rule built to predict VUR 653 had a stable specificity (ie. 46%), but a decreased sensitivity (ie. 64%) because of the time variability of PCT measurement. Some refinement may be warranted
Optimizaci贸n de la Asignaci贸n del Personal Docente con Base en una Evaluaci贸n Integral
Resumen: El desempe帽o del personal docente en la UAP Izcalli, actualmente se mide en conformidad con tres criterios importantes: 1) La apreciaci贸n del profesor realizada por los estudiantes, 2) La evaluaci贸n de la clase metodol贸gica y 3) Visita a clase por personal del 谩rea acad茅mica durante el per铆odo. Esta informaci贸n aunque 煤til, no es utilizada para la asignaci贸n de la carga laboral del docente en el per铆odo siguiente. En el presente trabajo, presentamos un modelo de programaci贸n lineal donde proponemos integrar toda la informaci贸n disponible sobre el desempe帽o docente, de tal forma, que la asignaci贸n de profesores considere todas los aspectos; tanto de evaluaci贸n cumplimiento, as铆 como sus restricciones. Esta propuesta de asignaci贸n, garantizar谩 la optimizaci贸n del personal docente y al mismo tiempo se reflejar谩 en un mayor aprovechamiento del estudiante. Abstract: The competence of teachers in the UAP Izcalli currently mesuared according to three major criteria: 1)Teacher appreciation by nstudents, 2)Evaluation of methodological class and 路3) visit to class by the academic are during the period. This information, While useful, But is not used for allocating the workload of teachers in the next period. In this paper, we present a linear programming model which we propose to integrate all available information on teacher performance, so that the allocation of teachers considers all aspects; Therefore evaluation, compliance and restrictions. This proposal will ensure the optimization allocation of teachers and at the same time will be reflected in highter student achievement
Libro: Avances de las Mujeres en las Ciencias las humanidades y todas las Disciplinas Creatividad e Innovaci贸n
Resumen: El desempe帽o del personal docente en la UAP Izcalli, actualmente se mide en conformidad con tres criterios importantes: 1) La apreciaci贸n del profesor realizada por los estudiantes, 2) La evaluaci贸n de la clase metodol贸gica y 3) Visita a clase por personal del 谩rea acad茅mica durante el per铆odo. Esta informaci贸n aunque 煤til, no es utilizada para la asignaci贸n de la carga laboral del docente en el per铆odo siguiente. En el presente trabajo, presentamos un modelo de programaci贸n lineal donde proponemos integrar toda la informaci贸n disponible sobre el desempe帽o docente, de tal forma, que la asignaci贸n de profesores considere todas los aspectos; tanto de evaluaci贸n cumplimiento, as铆 como sus restricciones. Esta propuesta de asignaci贸n, garantizar谩 la optimizaci贸n del personal docente y al mismo tiempo se reflejar谩 en un mayor aprovechamiento del estudiante. Abstract: The competence of teachers in the UAP Izcalli currently mesuared according to three major criteria: 1)Teacher appreciation by nstudents, 2)Evaluation of methodological class and 路3) visit to class by the academic are during the period. This information, While useful, But is not used for allocating the workload of teachers in the next period. In this paper, we present a linear programming model which we propose to integrate all available information on teacher performance, so that the allocation of teachers considers all aspects; Therefore evaluation, compliance and restrictions. This proposal will ensure the optimization allocation of teachers and at the same time will be reflected in highter student achievement