Zeewierteelt voor energie en industrie

Bedrijven gaan in de nabije toekomst mogelijk zeewieren kweken in onze Noordzee, op plantages voor de Nederlandse kust. De geteelde inheemse soorten leveren dan duurzame brandstoffen en grondstoffen voor de chemische industrie. Vanuit die visie werkt Ana López Contreras aan het project Zeewier Bioraffinage

Edge reconstructions in fractional quantum Hall systems

Two dimensional electron systems exhibiting the fractional quantum Hall effects are characterized by a quantized Hall conductance and a dissipationless bulk. The transport in these systems occurs only at the edges where gapless excitations are present. We present a {\it microscopic} calculation of the edge states in the fractional quantum Hall systems at various filling factors using the extended Hamiltonian theory of the fractional quantum Hall effect. We find that at $\nu=1/3$ the quantum Hall edge undergoes a reconstruction as the background potential softens, whereas quantum Hall edges at higher filling factors, such as $\nu=2/5, 3/7$, are robust against reconstruction. We present the results for the dependence of the edge states on various system parameters such as temperature, functional form and range of electron-electron interactions, and the confining potential. Our results have implications for the tunneling experiments into the edge of a fractional quantum Hall system.Comment: 11 pages, 9 figures; minor typos corrected; added 2 reference

Edge reconstruction in the fractional quantum Hall regime

The interplay of electron-electron interaction and confining potential can lead to the reconstruction of fractional quantum Hall edges. We have performed exact diagonalization studies on microscopic models of fractional quantum Hall liquids, in finite size systems with disk geometry, and found numerical evidence of edge reconstruction under rather general conditions. In the present work we have taken into account effects like layer thickness and Landau level mixing, which are found to be of quantitative importance in edge physics. Due to edge reconstruction, additional nonchiral edge modes arise for both incompressible and compressible states. These additional modes couple to electromagnetic fields and thus can be detected in microwave conductivity measurements. They are also expected to affect the exponent of electron Green's function, which has been measured in tunneling experiments. We have studied in this work the electric dipole spectral function that is directly related to the microwave conductivity measurement. Our results are consistent with the enhanced microwave conductivity observed in experiments performed on samples with an array of antidots at low temperatures, and its suppression at higher temperatures. We also discuss the effects of the edge reconstruction on the single electron spectral function at the edge.Comment: 19 pages, 12 figure

Quantum coherent control of highly multipartite continuous-variable entangled states by tailoring parametric interactions

The generation of continuous-variable multipartite entangled states is important for several protocols of quantum information processing and communication, such as one-way quantum computation or controlled dense coding. In this article we theoretically show that multimode optical parametric oscillators can produce a great variety of such states by an appropriate control of the parametric interaction, what we accomplish by tailoring either the spatio-temporal shape of the pump, or the geometry of the nonlinear medium. Specific examples involving currently available optical parametric oscillators are given, hence showing that our ideas are within reach of present technology.Comment: 14 pages, 5 figure

Duality cascades and duality walls

We recast the phenomenon of duality cascades in terms of the Cartan matrix associated to the quiver gauge theories appearing in the cascade. In this language, Seiberg dualities for the different gauge factors correspond to Weyl reflections. We argue that the UV behavior of different duality cascades depends markedly on whether the Cartan matrix is affine ADE or not. In particular, we find examples of duality cascades that can't be continued after a finite energy scale, reaching a "duality wall", in terminology due to M. Strassler. For these duality cascades, we suggest the existence of a UV completion in terms of a little string theory.Comment: harvmac, 24 pages, 4 figures. v2: references added. v3: reference adde

Theoretical predictions for the direct detection of neutralino dark matter in the NMSSM

We analyse the direct detection of neutralino dark matter in the framework of the Next-to-Minimal Supersymmetric Standard Model. After performing a detailed analysis of the parameter space, taking into account all the available constraints from LEPII, we compute the neutralino-nucleon cross section, and compare the results with the sensitivity of detectors. We find that sizable values for the detection cross section, within the reach of dark matter detectors, are attainable in this framework. For example, neutralino-proton cross sections compatible with the sensitivity of present experiments can be obtained due to the exchange of very light Higgses with m_{h_1^0}\lsim 70 GeV. Such Higgses have a significant singlet composition, thus escaping detection and being in agreement with accelerator data. The lightest neutralino in these cases exhibits a large singlino-Higgsino composition, and a mass in the range 50\lsim m_{\tilde\chi_1^0}\lsim 100 GeV.Comment: Final version to appear in JHEP. References added. LaTeX, 53 pages, 23 figure

Beta cell death by cell-free DNA and outcome after clinical islet transplantation

Background: Optimizing engraftment and early survival after clinical islet transplantation is critical to long-term function, but there are no reliable, quantifiable measures to assess beta cell death. Circulating cell free DNA (cfDNA) derived from beta cells has been identified as a novel biomarker to detect cell loss, and was recently validated in new-onset type 1 diabetes and in islet transplant patients. Methods: Herein we report beta cell cfDNA measurements after allotransplantation in 37 subjects and the correlation with clinical outcomes. Results: A distinctive peak of cfDNA was observed 1hr after transplantation in 31/37 (83.8%) of subjects. The presence and magnitude of this signal did not correlate with transplant outcome. The 1hr signal represents dead beta cells carried over into the recipient after islet isolation and culture, combined with acute cell death post infusion. Beta cell cfDNA was also detected 24hrs post-transplant (8/37 subjects, 21.6%). This signal was associated with higher 1-month insulin requirements (p=0.04), lower 1-month stimulated C-peptide levels (p=0.01) and overall worse 3-month engraftment, by insulin independence (ROC:AUC=0.70, p=0.03) and Beta 2 score (ROC:AUC=0.77, p=0.006). Conclusions: cfDNA-based estimation of beta cell death 24hrs after islet allotransplantation correlates with clinical outcome and could predict early engraftment.B.G.-L. is supported through the Alberta Innovates :Health Solutions (AIHS) Clinician Fellowship and through the CNTRP. A.P. is supported through AIHS Postgraduate Fellowship and CNTRP. A.M.J.S. is supported through AIHS, and holds a Canada Research Chair in Transplantation Surgery and Regenerative Medicine funded through the Government of Canada. A.M.J.S. is also funded by AIHS Collaborative Research and Innovation Opportunity Team Award and the Diabetes Research Institute Foundation of Canada (DRIFCan). Supported by grants from the Juvenile Diabetes Research Foundation (JDRF) (3-SRA-2014-38-Q-R, to Y.D. and A.M.J.S.), National Institute of Health (NIH) (HIRN grant UC4 DK104216, to Y.D.), DON foundation (Stichting Diabetes Onderzoek Nederland) (to Y.D), the European Union (ELASTISLET project, to Y.D.) and the Kahn foundation (to Y.D., R.S., and B.G.). Supported in part by a grant from The United States Agency for International Development (USAID) American Schools and Hospitals Abroad Program for the upgrading of the Hebrew University sequencing core facilit

Overexpression of wild-type human APP in mice causes cognitive déficits and pathological features unrelated to Abeta levels

Transgenic mice expressing mutant human amyloid precursor protein (APP) develop an age-dependent amyloid pathology and memory deficits, but no overt neuronal loss. Here, in mice overexpressing wild-type human APP (hAPPwt) we found an early memory impairment, particularly in the water maze and to a lesser extent in the object recognition task, but β-amyloid peptide (Aβ42) was barely detectable in the hippocampus. In these mice, hAPP processing was basically non-amyloidogenic, with high levels of APP carboxy-terminal fragments, C83 and APP intracellular domain. A tau pathology with an early increase in the levels of phosphorylated tau in the hippocampus, a likely consequence of enhanced ERK1/2 activation, was also observed. Furthermore, these mice presented a loss of synapse-associated proteins: PSD95, AMPA and NMDA receptor subunits and phosphorylated CaMKII. Importantly, signs of neurodegeneration were found in the hippocampal CA1 subfield and in the entorhinal cortex that were associated to a marked loss of MAP2 immunoreactivity. Conversely, in mice expressing mutant hAPP, high levels of Aβ42 were found in the hippocampus, but no signs of neurodegeneration were apparent. The results support the notion of Aβ- independent pathogenic pathways in Alzheimer's disease

Thermodynamics of an Anyon System

We examine the thermal behavior of a relativistic anyon system, dynamically realized by coupling a charged massive spin-1 field to a Chern-Simons gauge field. We calculate the free energy (to the next leading order), from which all thermodynamic quantities can be determined. As examples, the dependence of particle density on the anyon statistics and the anyon anti-anyon interference in the ideal gas are exhibited. We also calculate two and three-point correlation functions, and uncover certain physical features of the system in thermal equilibrium.Comment: 18 pages; in latex; to be published in Phys. Rev.