Characteristics of two conditioning regimens cyclophosphamide plus antithymocyte globulin versus cyclophosphamide plus busulfan in allogeneic stem cell transplantation for severe aplastic anemia

Universidade Federal de São Paulo, São Paulo, BrazilHosp Santa Marcelina, São Paulo, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilWeb of Scienc

Valores de energia digestível, metabolizável e do coeficiente de digestibilidade dos nutrientes do milho em diferentes níveis de carunchamento.

Milho BR-201 foi submetido a infestacao artificial por caruncho (Sitophilus zeamais) obtendo-se quatro lotes em diferentes niveis de carunchamento (1,79%, 10,27%; 17,49% e 38,15%). Quinze suinos machos castrados foram distribuidos em um delineamento inteiramente casualizado em tres repeticoes por tratamento. As racoes experimentais foram compostas por uma racao referencia e quatro racoes compostas de 75% da racao referencia e 25% do milho a ser estudado. A elevacao do nivel de carunchamento do milho reduziu o nivel de energia digestivel e o coeficiente de digestibilidade do extrato etereo do milho, mas nao alterou o coeficiente de digestibilidade da proteina bruta, da fibra bruta e da energia metabolizavel

Bioactive compounds of fractionated palm oil with a higher content of oleic acid.

BRS Manicoré cultivar is an interspecific hybrid between Elaeis oleifera and Elaeis guineensis(ISH OxG). It has shown high yield potential and genetic resistance to phytosanitary problems in cultivation in Brazil. Studies have indicated differences in the composition of ISH OxG and palm oils, as well as the influence of genotype and environment on palm oil characteristics. The aim of this study was to assess the distribution of fatty acids, carotenoids, and tocochromanols in the olein and stearin fractions of the oil produced by the ISH OxG cultivated in municipality of Una, state of Bahia, Brazil by liquid and gas chromatography. There were significant differences for fatty acids, carotenoids and total tocochromanols between olein and stearin (p<0.05). The olein was richer in oleic acid (59% vs 57%), while stearin was higher in saturated fatty acids (31% vs 29%), alpha and beta-carotene (232 vs 213 mg/Kg, and 347 vs 299 mg/Kg, respectively), alpha-tocotrienol (136 vs 90 mg/Kg), and alpha-tocopherol (52 vs 32 mg/Kg). No difference was observed for gamma-tocotrienol (598 ? 450 mg/kg) and delta-tocotrienol; nonetheless, the high content of the former in both fractions was notable. The ISH OxG oil fractions showed distinct patterns, indicating different applications.Título em português: Compostos bioativos de frações de óleo de palma com maior teor de ácido oleico

Primary cerebral alveolar rhabdomyosarcoma in adult

Primary cerebral rhabdomyosarcomas are very rare and malignant tumors that occur predominantly in the posterior fossa of pediatric patients. We report a rare case of primary cerebral rhabdomyosarcoma located in the supratentorial compartment of a 51 year-old woman together with a review of the pertinent Literature especially regarding the histological diagnosis and pitfalls

Developing an Evidence-Based Coexistence Strategy to Promote Human and Wildlife Health in a Biodiverse Agroforest Landscape

UIDB/04038/2020 UIDP/04038/2020Agroforest mosaics represent one of the most extensive human-impacted terrestrial systems worldwide and play an increasingly critical role in wildlife conservation. In such dynamic shared landscapes, coexistence can be compromised if people view wildlife as a source of infectious disease. A cross-disciplinary One Health knowledge base can help to identify evolving proponents and threats to sustainable coexistence and establish long-term project goals. Building on an existing knowledge base of human–wildlife interactions at Cantanhez National Park (NP), Guinea-Bissau, we developed a causal pathway Theory-of-Change approach in response to a newly identified disease threat of leprosy in the Critically Endangered western chimpanzee (Pan troglodytes verus). The goals of our project are to improve knowledge and surveillance of leprosy in humans and wildlife and increase capacity to manage human–wildlife interactions. We describe the core project activities that aim to (1) quantify space use by chimpanzees across Cantanhez NP and determine the distribution of leprosy in chimpanzees; (2) understand the health system and local perceptions of disease; and (3) identify fine-scale risk sites through participatory mapping of resources shared by humans and chimpanzees across target villages. We discuss the development of a biodiversity and health monitoring programme, an evidence-based One Health campaign, and a One Health environmental management plan that incorporates the sharing of space and resources, and the disease implications of human–non-human great ape interactions. We demonstrate the importance of multi-stakeholder engagement, and the development of strategy that fully considers interactions between people, wildlife, and the environment.publishersversionpublishe