MINERAL, PROTEIN, AND ENERGY SUPPLEMENTATION IN HEIFERS IN A NATIVE PAMPA BIOME PASTURE DURING WINTER

This study evaluated the effect of different supplements during winter on the performance of heifers in a native Pampa biome field using deferred grazing and evaluated the economic viability of each treatment. A total of 124 heifers from Brangus and Angus breeds, 18 months old, and with an average weight of 301.6 kg were included in this experiment. The treatments applied were: control with only native grassland, native grassland + 80P mineral salt treatment (MS), native grassland + protein salt treatment (PS), and native grassland + protein/energy salt treatment (PES). Besides the productive, botanical, and bromatological characteristics of the pasture, the average daily gain and the live weight gain per hectare were evaluated. The economic viability of the treatments was evaluated through partial budgeting. Weight loss was observed in all treatments. However, only the PES treatment differed from the others, with an average daily gain of -0.046 kg dia-1 (p value < 0.005). The MS treatment was the best regarding economic viability. Despite that, the smallest weight loss was observed in the PES treatment, which may be a determinant in the development and future performance of heifers. Despite the small net margin, this treatment did not incur additional costs to the system

BIOECONOMIC PERFORMANCE OF A FEEDLOT BULL WITH DIFFERENT GENETIC GROUPS

Livestock systems require a thorough analysis of zootechnical and financial indicators. In this sense, the objective of this study was to evaluate the bioeconomic performance of feedlot bulls with different genetic groups in 2012 and 2013. The experiment was carried out on a farm in Paragominas, State of Pará. The confined animals belonged to the Nellore (NE), ½ Angus ½ Nellore (AN) and ½ Charolais ½ Nellore (CH) breeds. The indicators analyzed were the cost of production and economic indicators. Additionally, zootechnical indicators were evaluated, being considered NE, AN, and CH as treatments in a completely randomized design. The financial results of the total production cost were R$118,493.21 in 2012, and R$ 111,166.35 in 2013, and the profitability obtained was 11% in 2012 and 8% in 2013. Regarding the zootechnical indicators, the CH genetic group showed superiority (P <0.01) compared to the NE genetic group for the variables initial weight (IW), final weight (FW), weight gain (WG), average daily weight gain (DWG), and carcass yield (CY). The confinement proved to be economically viable, with positive margins and satisfactory profitability, and the CH genetic group had the best indicators and the highest increase in the final revenue of the activity

Organoleptic characteristics of eggs produced by Japanese quails fed with levels of by-products from the soybean oil industry

By-products of the refining of vegetable oils can be used in the feeding of laying birds. However, they may alter the sensory properties of the eggs. Acidulated soy soapstock oil (ASS) is a by-product containing high amounts of free fatty acids (FFA) which are not well utilized by the animals. Therefore, the use of an emulsifier could help with the absorption of FFA. This study aimed to evaluate the effect of different levels of ASS in association with lecithin on the sensory properties of Japanese quail eggs. Eggs from Japanese quails fed diets with acidulated soy soapstock oil (ASS) and lecithin (LEC) were used. The treatments were: T1 - diet with 4% ASS; T2 - diet with 4% ASS + 1% LEC; T3 - diet with 8% ASS; T4- diet with 8% ASS + 1% LEC; T5 - diet with 4% degummed oil (DSO); T6 - diet whit 4% DSO + 1% LEC; T7- BD with 8% DSO; T8 - diet with 8% DSO + 1% LEC. Ten trained panelists evaluated the organoleptic properties of the eggs and each panelist was considered a replication. A 9 cm structured scale was used for verifying the following variables: intensity, brightness, characteristic odor, texture, fat taste, acid taste, rancid taste and residual taste. Additionally, a triangle test was used for evaluating some combinations of treatments. The use of ASS negatively affects some organoleptic characteristics. However, the association of ASS with LEC reduced such negative effects

Oral Squamous cell carcinoma: Are general practitioners trained to diagnose it properly?

This is a letter to editor, that discuss about the diagnose of oral squamous cell carcinoma and if are general practitioners trained to diagnose it properly.

Dietary restriction abrogates antibody production induced by a DNA vaccine encoding the mycobacterial 65 kDa heat shock protein

Abstract\ud \ud \ud \ud Background\ud \ud Protein-calorie malnutrition (PCM) is the most common type of malnutrition. PCM leads to immunodeficiency and consequent increased susceptibility to infectious agents. In addition, responses to prophylactic vaccines depend on nutritional status. This study aims to evaluate the ability of undernourished mice to mount an immune response to a genetic vaccine (pVAXhsp65) against tuberculosis, containing the gene coding for the heat shock protein 65 from mycobacteria.\ud \ud \ud \ud Methods\ud \ud Young adult female BALB/c mice were fed ad libitum or with 80% of the amount of food consumed by a normal diet group. We initially characterized a mice model of dietary restriction by determining body and spleen weights, hematological parameters and histopathological changes in lymphoid organs. The ability of splenic cells to produce IFN-gamma and IL-4 upon in vitro stimulation with LPS or S. aureus and the serum titer of specific IgG1 and IgG2a anti-hsp65 antibodies after intramuscular immunization with pVAXhsp65 was then tested.\ud \ud \ud \ud Results\ud \ud Dietary restriction significantly decreased body and spleen weights and also the total lymphocyte count in blood. This restriction also determined a striking atrophy in lymphoid organs as spleen, thymus and lymphoid tissue associated with the small intestine. Specific antibodies were not detected in mice submitted to dietary restriction whereas the well nourished animals produced significant levels of both, IgG1 and IgG2a anti-hsp65.\ud \ud \ud \ud Conclusion\ud \ud 20% restriction in food intake deeply compromised humoral immunity induced by a genetic vaccine, alerting, therefore, for the relevance of the nutritional condition in vaccination programs based on these kinds of constructs.The present study was supported by a scholarship award to Larissa L. W. Ishikawa by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Brazil.The present study was supported by a scholarship award to Larissa L. W. Ishikawa by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Brazil

CARCINOMA ESPINOCELULAR ORAL: UM PANORAMA ATUAL

Introdução: O carcinoma espinocelular (CEC) representa o tumor mais frequente dentre todos dos cânceres localizados na topografia de cabeça e pescoço. Segundo o Ministério da Saúde, a estimativa é que em 2007 cerca de 10,91 casos  de câncer de boca foram diagnosticados para cada 100.000 homens e 3,58 para cada 100.000 mulheres. Métodos: Este presente estudo é uma revisão da literatura, que foi baseado, e posteriormente construído, através da análise de dados, levantados na literatura, sobre o tema abordado. Foram realizadas pesquisas bibliográficas por meio, exclusivamente, das bases de dados da Pubmed, Scielo e LILACS, onde selecionou bibliografias entre os anos de 2001 a 2016.Revisão bibliografia: O câncer da cavidade oral, apesar de todos os avanços relacionados às técnicas de tratamento, ainda apresenta um prognóstico desfavorável, com elevadas taxas de mortalidade.Conclusão: O câncer de boca é uma patologia incidente mundialmente, sendo representada, principalmente, através do carcinoma espinocelular. Por isso, se faz necessário o seu estudo, para que assim, o diagnóstico e tratamento precoce sejam prontamente instituídos

Relationship between lead in the blood and performance in the abilities from hearing process

INTRODUÇÃO: A contaminação por chumbo afeta todos os sistemas do corpo humano, principalmente o sistema nervoso. OBJETIVO: Investigar se há correlação entre o nível de plumbemia e o desempenho em testes do processamento auditivo. MÉTODO: Estudo retrospectivo. 73 crianças, com idade entre 7 a 15 anos, residentes em uma área onde houve emissão de partículas de chumbo acima do permitido, com nível de plumbemia maior ou igual a 10 microgramas/dL, exames audiológicos (audiometria e timpanometria) dentro dos padrões de normalidade. Para avaliar o processamento auditivo foram utilizados o Teste de Fusão Auditiva-Revisado (AFT-R), subteste 1, e o Teste Dicótico de Dígitos (etapa de integração binaural). Foi utilizado o teste de Spearman para verificar a correlação entre os dados. RESULTADOS: O nível de plumbemia variou de 10 a 30,2microgamas/dL, sendo a média correspondente a 15,8 microgramas/dL (desvio-padrão de 4,8). Dessas crianças, 60,3% apresentaram desempenho ruim no teste AFT-R, ou seja, resultados superiores a 60ms. Quanto ao Teste Dicótico de Dígitos, 46,2% das crianças apresentaram desempenho ruim para a orelha direita e 67,3% apresentaram desempenho ruim na orelha esquerda. Conforme o resultado do teste de correlação de Spearman, não houve significância estatística entre o nível de chumbo e os resultados dos testes do processamento auditivo. CONCLUSÃO: Não houve correlação entre o nível de plumbemia e o desempenho nas habilidades do processamento auditivo, entretanto crianças contaminadas pelo chumbo apresentaram desempenho inferior nas habilidades do processamento auditivo

Oral Kaposi sarcoma development is associated with HIV viral load, CD4+ count and CD4+/CD8+ ratio

Kaposi?s sarcoma (KS) is an uncommon, multifocal and angioproliferative lesion, which demonstrates a poor prognosis. The aim of the present research was to explore the association of HIV viral load, CD4+ and CD8+ counts and the CD4+/CD8+ ratio on the risk of oral Kaposi?s sarcoma (KS) development. A total of 62 patients were retrieved from March 2008 to October 2020 from the files of two oral pathology centres. Clinical, laboratory and follow-up data were retrieved from their medical files. Poisson regression was used to explore the role of history of immunosuppression and its association with oral KS development. A P-value <0.05 was considered significant. Sixty-two patients were included in the present study (32 with oral KS and 30 with no presentation of lesions anywhere on the body). Patients with oral KS presented a mean age of 32.6 years, and male patients were more affected. The hard palate (15 cases; 46.8%) was the main anatomical site affected. The lesions were mostly presented as swellings (13 cases; 40.6%) and nodules (12 cases; 37.5%). Systemic manifestations were also observed, including candidiasis (4 cases; 12.5%), bacterial infection (3 cases; 9.3%), tuberculosis (3 cases; 9.3%), herpes simplex (3 cases; 9.3%) and pneumonia (3 cases; 9.3%). A significant correlation was observed between HIV viral load, CD4+ count and the CD4+/CD8+ ratio with oral KS development. HIV viral load, CD4+ count and the CD4+/CD8+ ratio are associated with oral KS development

Proposta de antibioticoterapia empírica para tratamento de SEPSE primária em CTI / Empirical antibiotic therapy proposal for the treatment of primary SEPSIS in the ICU

Os antimicrobianos se apresentam como uma das principais drogas utilizadas nos centros de terapia intensiva (CTIs). Contudo, sua indicação ainda é preocupantemente caracterizada por tratamentos inadequados, apresentando um consequente aumento de bactérias multirresistentes. Nesse contexto, tem-se a antibioticoterapia empírica como importante ferramenta para redução de taxas de mortalidade em quadros de sepse primária. Assim, este estudo objetiva avaliar o perfil de sensibilidade antimicrobiana dos agentes etiológicos de sepse primária em CTI de adultos, embasando terapia empírica para tratamento dessa complicação e, por conseguinte, contribuindo para a elaboração de estratégias de uso racional dos antimicrobiano

Consumo de alimentos industrializados em diabéticos acompanhados em ambulatório: Consumption of processed foods in diabetics followed up in an outpatient clinic

A dieta ocidental, caracterizada pela alta densidade calórica, e o sedentarismo, são os principais fatores que aumentam o risco para as doenças crônicas não transmissíveis,&nbsp; como a obesidade e a diabetes mellitus tipo 2. Esse tipo de dieta engloba alimentos ricos em gorduras saturadas, açúcar e sódio, que são características dos alimentos industrializados, estando cada vez mais presentes na rotina da população. O objetivo deste trabalho é identificar as mudanças na frequência de consumo de alimentos processados e ultraprocessados, em diabéticos, durante o acompanhamento nutricional. Estudo é transversal alinhada a uma coorte retrospectiva, com Diabéticos tipo 2 maior ou igual a 60 anos, no ambulatório de nutrição/diabetes, do Núcleo de Atenção ao Idoso, da Universidade Federal de Pernambuco, atendidos no período de 2013 a 2019. Foram analisadas variáveis sociodemográficas (sexo e idade, procedência), clínicas (hipertensão arterial sistêmica e dislipidemia), de estilo de vida (prática de atividade física e etilismo), antropométricas (peso e altura) e dietética (recordatório de 24 horas). Foram estudados 230 pacientes, na faixa de 60 a 74 anos (83%), com tempo de doença de 1-5 anos (36,5%), sexo feminino (80%), procedentes da Região Metropolitana do Recife (70%), com presença de hipertensão arterial sistêmica (81,7%), dislipidemia (62,2%) e excesso de peso (59,1%). A prática de atividade física e o etilismo não foram predominantes. Os pacientes foram acompanhados durante 3 consultas, com período de 6 meses entre elas. Ocorreu variação no consumo de grupos de alimentos entre a 1ª e a última consulta de nutrição, com redução significativa de embutidos (8,3%) e de pão (18,3%), enquanto aumentou o consumo de frutas (29,5%) e raízes (6,5%). A frequência de consumo de alimentos industrializados no grupo de diabéticos foi alta nos dois momentos avaliados, com redução significativa após o acompanhamento nutricional, que evidenciou efeitos positivos na qualidade da alimentação do paciente