Contribuições dos Serious Games para a Neuroplasticidade, Aprendizado Motor e Reabilitação Neurológica: Revisão Integrativa

The objective of this study was to investigate the contributions of serious games to neuroplasticity and motor learning in the rehabilitation process of pediatric and adult patients with neurological diseases. Therefore, an integrative review of scientific articles indexed in Google Scholar was carried out; CAPES and IEEE Xplore Digital periodicals, combining controlled and uncontrolled descriptors, in English and Portuguese, without delimiting the year of publication. It was observed that the use of serious games is a viable option in the rehabilitation process, providing psycho-emotional gains, such as motivation and engagement, in addition to motor gains, such as increased agility, improved gross and fine motor control, and increased response speed, in addition to being a playful option for adult and pediatric patients.O objetivo deste trabalho foi investigar as contribuições dos serious games para a neuroplasticidade e o aprendizado motor no processo de reabilitação de pacientes pediátricos e adultos, com doenças neurológicas. Para tanto, foi realizada uma revisão integrativa de artigos científicos indexados no Google Scholar; Periódicos CAPES e IEEE Xplore Digital, combinando descritores controlados e não controlados, em inglês e português, sem delimitação de ano de publicação. Observou-se que o uso dos serious games é uma opção viável no processo de reabilitação, proporcionando ganhos psicoemocionais, como motivação e engajamento além de ganhos motores, como aumento da agilidade, melhora do controle motor grosso e fino, e aumento velocidade de resposta, além de ser uma opção lúdica para pacientes adultos e pediátricos

Four new coordination polymers involving transition metals with 1,2,4,5-benzenetetracarboxylate and pyridyl-donor ligand di(4-pyridyl) sulfide

AbstractFour new coordination polymers namely {[Mn2(BT)(DPS)2(H2O)6]·10H2O}n (MnBTDPS), {[Co2(BT)(DPS)2(H2O)6]·10H2O}n (CoBTDPS), {[Cu2(BT)(DPS)(H2O)4]·5H2O}n (CuBTDPS) and {[Zn2(BT)(DPS)2]·6H2O}n (ZnBTDPS), where BT=1,2,4,5-benzenetetracarboxylate and DPS=di(4-pyridyl) sulfide, were synthesized and characterized by thermal analysis, vibrational spectroscopy (Raman and infrared) and single crystal X-ray diffraction analysis. In all compounds, the DPS ligands are coordinated to metal sites in a bridging mode and the carboxylate moiety of BT ligands adopts a monodentate coordination mode, as indicated by the Raman spectra data through the Δν (νasym(COO)−ν sym(COO)) value. According to X-ray diffraction analysis, MnBTDPS and CoBTDPS are isostructural and in these cases, the metal centers exhibit a distorted octahedral geometry. In CuBTBPP, the Cu2+ centers geometries are best described as square-pyramids, according to the trigonality index τ=0.14 for Cu1 and τ=0.10 for Cu2. On the other hand, in ZnBTDPS, the Zn2+ sites adopt a tetrahedral geometry. Finally, the four compounds formed two-dimensional sheets that are connected to each other through hydrogen bonding giving rise to three-dimensional supramolecular arrays

Influence of physical activity on self-esteem and anxiety during pregnancy: A longitudinal prospective study

Women’s pregnancy increases the odds of developing anxiety, depression, and low self-esteem. Physical activity can reduce the severity of maternal mental disorders and postpartum symptoms. The aim was to evaluate self-esteem, anxiety, and physical activity patterns among healthy pregnant women during three gestational trimesters (GTs). A longitudinal prospective study involving 248 Portuguese pregnant women, monitored for a year during all GTs, was conducted. Self-reported questionnaires were used to collect personal and obstetric data, and Rosenberg’s Self-Esteem Scale, Zung Anxiety Scale, and a Pregnancy Physical Activity Questionnaire were applied. A total of 152 women presented valid follow-up data considered for analysis. All test scores do not present normality (p < 0.001). Over the gestational trimesters, the Zung anxiety scores did not show a significant change between GTs. However, the self-esteem values reduced significantly from 1st to 2nd GT: (1st GT = 43.94 (±9.94) [95%CI: 42.37 to 45.53]; 2nd GT = 27.27 (±9.64) [95%CI: 25.74 to 28.81]; 3rd GT = 25.71 (±10.52) [95%CI: 24.04 to 27.39]; p < 0.001), remaining stable in the last GT. Moderate to vigorous (2nd GT = 73.43 (±88.69) [95%CI: 59.34 to 87.54]; 3rd GT = 65.05 (±82.65) [95%CI: 51.92 to 78.19]; p = 0.008), vigorous (1st GT = 0.45 (±3.95) [95%CI: 0.83 to 2.08]; 2nd GT = 1.63 (±3.52) [95%CI: 1.07 to 2.19]; 3rd GT = 0.81 (±2.16) [95%CI: 0.46 to 1.15]; p = 0.0475), and light (2nd GT = 101.68 (±48.77) [95%CI: 93.93 to 109.44]; 3rd GT = 98.42 (±49.05) [95%CI: 90.62 to 106.22]; p < 0.001) physical activity levels were significantly reduced throughout the GTs, but the time spent in sedentary activities did not change. In this follow-up study, it was possible to identify a critical point in the 2nd GT, when the drastic reduction in physical activity levels coincided with periods of lower self-esteem scores. However, anxiety levels do not seem to change over GTs.info:eu-repo/semantics/publishedVersio

Organizational culture and financial performance: evidence in companies listed in the Brazil Index 100

Purpose: The study investigates the relationship between organizational culture and financial performance of companies classified in the IBrX 100. Methodology: The organizational culture of 83 companies were analyzed through textual analysis, based on the cultural typologies developed by Cameron et al. (2006) and the performance data were taken from Thomson Reuters®. Results: The results of the multiple linear regression highlight that organizational culture is related in different ways with financial performance. However, not all dimensions of culture had the same relation in promoting performance. The control dimensions and the creative impact financial performance. On the other hand, cultural orientations aimed at competitiveness and collaboration are not related to performance. From this perspective, financial performance incorporates the two main aspects of organizational culture: (i) the permeability of innovative elements and flexibility; and (ii) the conduction of processes through efficiency and operational control. Study Contributions: The research offers society an explicit mapping of organizational culture typifications, so in the long term this document can serve as strategic information for social institutions to build mechanisms that maximize the informational quality and timeliness of accounting narratives. From a theoretical point of view, the research contributes to fostering discussions about the positionality of accounting narratives with regard to influencing the company's performance and culture

Cultura organizacional e desempenho financeiro: evidências em empresas listadas no Índice Brasil 100

Objetivo: O estudo investiga a relação entre cultura organizacional e desempenho financeiro de empresas listadas no IBrX 100. Metodologia: Analisou-se a cultura organizacional de 83 empresas por meio da análise textual, a partir das tipologias culturais desenvolvidas por Cameron et al. (2006) e os dados referentes ao desempenho foram extraídos da Thomson Reuters®. Resultados: Os resultados da regressão linear múltipla destacam que a cultura organizacional se relaciona de diferentes formas com o desempenho financeiro. No entanto, nem todas as dimensões da cultura tiveram a mesma relação na promoção do desempenho. As dimensões de controle e a criativa tem impacto no desempenho financeiro. Já as orientações culturais voltadas para a competitividade e para colaboração não se relacionam com o desempenho. Nessa perspectiva, o desempenho financeiro incorpora dois aspectos principais da cultura organizacional: (i) a permeabilidade de elementos inovadores e de flexibilidade; e (ii) a condução de processos por meio da eficiência e controle operacional. Contribuições do Estudo: A pesquisa oferece para sociedade um mapeamento explícito das tipificações de cultura organizacional, assim em longo prazo esse documento pode servir de informações estratégicos para as instituições sociais construírem mecanismos que maximizem a qualidade e tempestividade informacional das narrativas contábeis. Do ponto de vista teórico a pesquisa contribui para o fomento das discussões a respeito da posicionalidade das narrativas contábeis no que tange influenciar o desempenho e a cultura da companhia

Characteristics of resistance training-based protocols in older adults with sarcopenic obesity: a scoping review of training procedure recommendations

Background: Sarcopenic obesity (SO) is a clinical and functional disease characterized by the coexistence of obesity and sarcopenia. Resistance training (RT) characteristics for older adults with sarcopenia or obesity are already well established in the scientific literature. Nonetheless, we still do not know how detailed the RT protocols are described for older adults with SO. Therefore, we aimed to analyze the characteristics of RT programs, including each of their variables, recommended for older adults with SO. Methods: This is a scoping review study that was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis for Scoping Reviews. The search was carried out until November 2022 in PubMed/MEDLINE, EMBASE, Cochrane Library, Web of Science, Scopus, LILACS, Google Scholar, and medRxiv databases. The studies included SO diagnosis and RT as an intervention strategy. The RT variables analyzed were as follows: exercise selection, the volume of sets, the intensity of load, repetition cadence, rest interval between sets, and weekly frequency. Results: A total of 1,693 studies were identified. After applying the exclusion criteria, 15 studies were included in the final analysis. The duration of the RT intervention ranged from 8 to 24 weeks. All studies included full-body routines, with single/multi-joint exercises. Regarding the volume of sets, some studies fixed it in three sets, whereas others varied between one and three sets. The load was reported by repetition range and the weight lifted, elastic-band color/resistance, percentage of one repetition maximum, or perceived exertion scale. Repetition cadence was fixed in some studies, while it was self-selected between concentric and eccentric phases in others. The interval between sets of rest varied from 30 to 180 s. All studies reported progression overload during the interventions.info:eu-repo/semantics/publishedVersio

Association Between Body Image and Mental Health in Adolescents: A Social Issue

The construct of esthetic beauty is culturally and socially determined and widely disseminated by the media. The body image dissatisfaction (BID) is considered a public health problem, it is an important risk factor for disorders related to mental health, which is highly prevalent in adolescents and has an impact on social behavior. We aimed to evaluate the possible association between BID and the mental health aspects of depression and risk of eating disorders and identify the prevalence in adolescent boys and girls. The sample consisted of 308 adolescent students: 167 girls (54.2%) and 141 boys (45.8%). BID was identified by the silhouette scale. The Childhood Depression Scale (CDS) and Eating Attitudes Test (EAT-26) were used to assess MH. The chi-squared contingency test showed an association between body image and mental health variables in both sexes. Results: 70.1% of the girls and 76.6% of the boys exhibited BID. The girls demonstrated a significant association between body image and depressive symptoms (X(1) = 8.523; p = 0.004) and the risk of ED (X(1) = 14.281; p = 0.000). However, the boys exhibited no interactions between body image and mental health-related factors. Although BID was high in adolescents of both sexes, it may be a marker for depression and eating disorders in girls.A construção da beleza estética é cultural e socialmente determinada e amplamente divulgada pela mídia. A insatisfação com a imagem corporal (BID), considerada um problema de saúde pública, é um importante fator de risco para transtornos relacionados à saúde mental que apresenta alta prevalência em adolescentes e impacta sobre o comportamento social. Objetivamos avaliar a possível associação entre BID e os aspectos de saúde mental da depressão e risco de transtornos alimentares e identificar a prevalência em meninos e meninas adolescentes. Método: A amostra foi composta por 308 adolescentes escolares: 167 meninas (54,2%) e 141 meninos (45,8%). O BID foi identificado pela escala de silhueta. A Escala de Depressão na Infância (CDS) e o Teste de Atitudes Alimentares (EAT-26) foram utilizados para avaliar a HM. O teste de contingência qui-quadrado mostrou associação entre a imagem corporal e as variáveis de saúde mental em ambos os sexos. Resultados: 70,1% das meninas e 76,6% dos meninos apresentaram BID. As meninas demonstraram associação significativa entre imagem corporal e sintomas depressivos (X(1) = 8,523; p = 0,004) e risco de TA (X(1) = 14,281; p = 0,000). No entanto, os meninos não exibiram interações entre a imagem corporal e os fatores relacionados à saúde mental. Conclusão: Embora o BID tenha sido elevado em adolescentes de ambos os sexos, pode ser um marcador de depressão e transtornos alimentares em meninas

Covid-19 and oral manifestations: a narrative review

The aim of this review was to analyze the oral manifestations of COVID-19. A systematic literature review was carried out using the following databases: Cochrane Library, Embase, PubMed and Web of Science; this yielded 2497 articles, and 28 met the criteria for inclusion. The searches were carried out from October to December 2021. The articles show that oral alterations present as manifestations of mild cases of COVID-19, but that these can also occur in severe cases of the disease, due to the existence of several factors, increasing the risk of death. Thus, there are many explanations for the development of oral manifestations of COVID-19; they can be related to age, sex, comorbidities, among other factors. Conclusion: Although there is no clinical pattern of the disease, the most common manifestations in the literature are anosmia, dysgeusia, erosions, halitosis, ulcerations and xerostomia. Therefore, this emphasizes the importance of multidisciplinary understanding of the disease when analyzing and diagnosing the oral manifestations of COVID-19

March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity.

In transplantation, donor dendritic cells (do-DCs) initiate the alloimmune response either by direct interaction with host T cells or by transferring intact donor MHC to host DCs. However, how do-DCs can be targeted for improving allograft survival is still unclear. Here we show CD103+ DCs are the major do-DC subset involved in the acute rejection of murine skin transplants. In the absence of CD103+ do-DCs, less donor MHC-II is carried to host lymph nodes, fewer allogenic T cells are primed and allograft survival is prolonged. Incubation of skin grafts with the anti-inflammatory mycobacterial protein DnaK reduces donor MHC-II on CD103+DCs and prolongs graft survival. This effect is mediated through IL-10-induced March1, which ubiquitinates and decreases MHC-II levels. Importantly, in vitro pre-treatment of human DCs with DnaK reduces their ability to prime alloreactive T cells. Our findings demonstrate a novel therapeutic approach to dampen alloimmunity by targeting donor MHC-II on CD103+DCs