The Spanish Pancreatic Club's recommendations for the diagnosis and treatment of chronic pancreatitis: Part 2 (treatment)

Chronic pancreatitis (CP) is a complex disease with a wide range of clinical manifestations. This range comprises from asymptomatic patients to patients with disabling symptoms or complications. The management of CP is frequently different between geographic areas and even medical centers. This is due to the paucity of high quality studies and clinical practice guidelines regarding its diagnosis and treatment. The aim of the Spanish Pancreatic Club was to give current evidence-based recommendations for the management of CP. Two coordinators chose a multidisciplinary panel of 24 experts on this disease. These experts were selected according to clinical and research experience in CP. A list of questions was made and two experts reviewed each question. A draft was later produced and discussed with the entire panel of experts in a face-to-face meeting. The level of evidence was based on the ratings given by the Oxford Centre for Evidence-Based Medicine. In the second part of the consensus, recommendations were given regarding the management of pain, pseudocysts, duodenal and biliary stenosis, pancreatic fistula and ascites, left portal hypertension, diabetes mellitus, exocrine pancreatic insufficiency, and nutritional support in CP

The Spanish Pancreatic Club recommendations for the diagnosis and treatment of chronic pancreatitis: Part 1 (diagnosis)

Chronic pancreatitis (CP) is a relatively uncommon, complex and heterogeneous disease. The absence of a gold standard applicable to the initial phases of CP makes its early diagnosis difficult. Some of its complications, particularly chronic pain, can be difficult to manage. There is much variability in the diagnosis and treatment of CP and its complications amongst centers and professionals. The Spanish Pancreatic Club has developed a consensus on the management of CP. Two coordinators chose a multidisciplinary panel of 24 experts on this disease. A list of questions was drafted, and two experts reviewed each question. Then, a draft was produced and shared with the entire panel of experts and discussed in a face-to-fac

Els treballs de fi de grau a la Universitat de Barcelona

Podeu consultar la versió castellana al camp recurs relacionat.La implantació dels títols de grau ha suposat un repte per a les universitats, que han hagut d'adaptar els seus projectes formatius a les directrius de l’Espai Europeu d’Educació Superior. Un dels aspectes importants d’aquest procés ha estat l'obligació d’incorporar els treballs de fi de grau (TFG) a l’estructura curricular dels plans d’estudis. Aquesta tasca ha estat complexa i, a més, s’ha vist dificultada per la poca tradició que la majoria de facultats i escoles universitàries tenien en el disseny, l'organització i l'avaluació d’aquest tipus de treball. Uns quants cursos després d’haver-se posat en marxa els TFG, l’Institut de Ciències de l’Educació (ICE) de la Universitat de Barcelona va voler oferir als diferents centres de la UB una plataforma de reflexió i debat on poguessin compartir experiències, plantejar dubtes, analitzar models de bones pràctiques i recollir idees per millorar els seus projectes. A tal efecte, des de la Secció d’Universitat de l’ICE, es va organitzar la jornada «Els treballs de fi de grau a la UB». Aquest quadern recull les comunicacions presentades, sintetitza el debat que van generar i presenta les conclusions a què es va arribar

Los trabajos de fin de grado en la Universidad de Barcelona

Podeu consultar la versió catalana al camp recurs relacionat.[spa] La implantación de los títulos de grado ha supuesto un reto para las universidades, que han tenido que adaptar sus proyectos formativos a las directrices del Espacio Europeo de Educación Superior. Uno de los aspectos importantes de este proceso ha sido la obligación de incorporar los trabajos de fin de grado (TFG) a la estructura curricular de los planes de estudios. Esta tarea ha sido compleja y, además, se ha visto dificultada por la poca tradición que la mayoría de facultades y escuelas universitarias tenían en el diseño, organización y evaluación de esta clase de trabajo. Después de varios cursos de haberse puesto en marcha los TFG, el Instituto de Ciencias de la Educación (ICE) de la Universidad de Barcelona quiso ofrecer a los diferentes centros de la UB una plataforma de reflexión y debate donde pudieran compartir experiencias, plantear dudas, analizar modelos de buenas prácticas y recoger ideas para mejorar sus proyectos. A tal efecto, desde la Sección de Universidad del ICE se organizó la jornada «Los trabajos de fin de grado en la UB». Este cuaderno recoge las comunicaciones presentadas, sintetiza el debate que generaron y presenta las conclusiones a que se llegó.[eng] The phase-in of undergraduate degrees conforming to the guidelines of the European Higher Education Area has been a challenge for universities as far as their training projects are concerned. An important aspect of this process was the need to incorporate the Bachelor’s Degree Final Project (TFG) to the structure of their curricula. This task has been complex and been hampered also by the lack of tradition that most faculties and university colleges had in the design, organization and evaluation of these types of project. Several years after launching the TFG, the Institute of Education Sciences (ICE) of the University of Barcelona (UB) organized the «The Bachelor’s Degree Final Project» conference to offer different centres of the UB a space for reflection and debate to be able to share experiences, ask questions, analyse models of good practices and gather ideas for improving their projects. The present booklet includes papers, summarizes the debate that many and varied contributions generated and outlines the final conclusions reached at this conference

Challenge B: Human sciences in transition scenarios

Coordinators: Josep Martí Pérez (IMF, CSIC), Idoia Murga Castro (IH, CSIC).This challenge is formulated in terms of “humanities in transition,” that is, their approach and articulation in the face of the changes they must undergo to achieve the social weight that, due to their intrinsic relevance, should correspond to them. Faced with these situations that would demand a reinforcement in research and dissemination in diverse aspects of the humanities, from multiple perspectives, paradoxically an adverse panorama is drawn for the development and dissemination of humanistic knowledge, which concerns different factors. Some are related to the consideration of the area of knowledge itself, its organization within the scientific system, the questioning of its own limits, and the interaction with another knowledge. Considering current transition scenarios does not mean having to abandon old objectives, but it adds to the work conducted new objects of study closely related to current reality, such as: the informational revolution; the relations with the ecosystem and the environmental crisis; globalization; the intensification of human mobility and migration flows; the growing economic and social inequality; the frictions derived from the articulation of collective identities; the decolonization of discourses; demographic dynamics; integration of technological advances; and viability and support for alternative models of society.Peer reviewe

Effects of Platelet-Rich Plasma (PRP) on a Model of Renal Ischemia-Reperfusion in Rats.

Renal ischemia-reperfusion injury is a major cause of acute renal failure, causing renal cell death, a permanent decrease of renal blood flow, organ dysfunction and chronic kidney disease. Platelet-rich plasma (PRP) is an autologous product rich in growth factors, and therefore able to promote tissue regeneration and angiogenesis. This product has proven its efficacy in multiple studies, but has not yet been tested on kidney tissue. The aim of this work is to evaluate whether the application of PRP to rat kidneys undergoing ischemia-reperfusion reduces mid-term kidney damage. A total of 30 monorrenal Sprague-Dawley male rats underwent renal ischemia-reperfusion for 45 minutes. During ischemia, PRP (PRP Group, n = 15) or saline solution (SALINE Group, n = 15) was administered by subcapsular renal injection. Control kidneys were the contralateral organs removed immediately before the start of ischemia in the remaining kidneys. Survival, body weight, renal blood flow on Doppler ultrasound, kidney weight, kidney volume, blood biochemistry and histopathology were determined for all subjects and kidneys, as applicable. Correlations between these variables were searched for. The PRP Group showed significantly worse kidney blood flow (p = 0.045) and more histopathological damage (p<0.0001). Correlations were found between body weight, kidney volume, kidney weight, renal blood flow, histology, and serum levels of creatinine and urea. Our study provides the first evidence that treatment with PRP results in the deterioration of the kidney's response to ischemia-reperfusion injury

Renal blood flow before and one week after ischemia-reperfusion.

<p>Renal blood flow before and one week after ischemia-reperfusion.</p

Survival function: Kaplan-Meier graph.

<p>p = 0.073.</p

Histological damage.

<p>Non-ischemic vs. ischemic kidneys.</p