Reoperation rates following intramedullary nailing versus external fixation of Gustilo Type 3A open tibia shaft fractures

Background: Open tibia fractures are among the most difficult to manage due to the lack of soft tissue coverage and poor blood supply. This is especially true in developing settings primarily due to a lack of resources. Both locked Intramedullary Nailing (IM) and External Fixation (EF) are two possible modalities for surgical treatment of open tibia fractures. However, it is unknown at this time which one is most suitable in low resource regions especially with regards to the risk of serious complications requiring reoperation. This study was conducted to identify which method is safest and minimizes this risk in patients with open tibia fractures.Methodology: A prospective cohort study of Gustilo 3A open tibia shaft factures treated either by intramedullary nailing or external fixation was conducted from March 2013 to February 2014 at Muhimbili Orthopaedic Institute (Dar es Salaam, Tanzania). Follow-up was conducted at 2, 6 10, 14, and 18 weeks postoperatively. The primary outcome assessed was all-cause reoperation.Results: Fifty patients were enrolled and completed follow-up at all-time points; twenty-six were treated with IM nail and twenty-four were treated by EF. There were 9 (37.5%) EF patients who required reoperation compared to 1(3.8%) IM nail patient (p=0.004). Reasons for reoperation among EF patients were infection (2 patients), malalignment (3 patients), and delayed union (4 patients). The one IM nail patient presented with signs of infection and wound dehiscence at 14 weeks postoperatively. No patients presented with hardware failure or malrotation.Conclusion: Treatment of Gustilo Type 3A open tibia shaft fractures with interlocking intramedullary nailing results in lower reoperation rate in the early stages of treatment compared to uniplanar external fixation.Keywords: Orthopaedic surgery, Tanzania, Intramedullary nail, External fixation, Open tibia fractur

Nonlinear hyperbolic systems: Non-degenerate flux, inner speed variation, and graph solutions

We study the Cauchy problem for general, nonlinear, strictly hyperbolic systems of partial differential equations in one space variable. First, we re-visit the construction of the solution to the Riemann problem and introduce the notion of a nondegenerate (ND) system. This is the optimal condition guaranteeing, as we show it, that the Riemann problem can be solved with finitely many waves, only; we establish that the ND condition is generic in the sense of Baire (for the Whitney topology), so that any system can be approached by a ND system. Second, we introduce the concept of inner speed variation and we derive new interaction estimates on wave speeds. Third, we design a wave front tracking scheme and establish its strong convergence to the entropy solution of the Cauchy problem; this provides a new existence proof as well as an approximation algorithm. As an application, we investigate the time-regularity of the graph solutions $(X,U)$ introduced by the second author, and propose a geometric version of our scheme; in turn, the spatial component $X$ of a graph solution can be chosen to be continuous in both time and space, while its component $U$ is continuous in space and has bounded variation in time.Comment: 74 page

VSCAN: An Enhanced Video Summarization using Density-based Spatial Clustering

In this paper, we present VSCAN, a novel approach for generating static video summaries. This approach is based on a modified DBSCAN clustering algorithm to summarize the video content utilizing both color and texture features of the video frames. The paper also introduces an enhanced evaluation method that depends on color and texture features. Video Summaries generated by VSCAN are compared with summaries generated by other approaches found in the literature and those created by users. Experimental results indicate that the video summaries generated by VSCAN have a higher quality than those generated by other approaches.Comment: arXiv admin note: substantial text overlap with arXiv:1401.3590 by other authors without attributio

The SDSS spectroscopic catalogue of white dwarf-main-sequence binaries: new identifications from DR 9–12

We present an updated version of the spectroscopic catalogue of white dwarf-main-sequence (WDMS) binaries from the Sloan Digital Sky Survey (SDSS). We identify 938 WDMS binaries within the data releases (DR) 9–12 of SDSS plus 40 objects from DR 1–8 that we missed in our previous works, 646 of which are new. The total number of spectroscopic SDSS WDMS binaries increases to 3294. This is by far the largest and most homogeneous sample of compact binaries currently available. We use a decomposition/fitting routine to derive the stellar parameters of all systems identified here (white dwarf effective temperatures, surface gravities and masses, and secondary star spectral types). The analysis of the corresponding stellar parameter distributions shows that the SDSS WDMS binary population is seriously affected by selection effects. We also measure the Na I λλ 8183.27, 8194.81 absorption doublet and H α emission radial velocities (RV) from all SDSS WDMS binary spectra identified in this work. 98 objects are found to display RV variations, 62 of which are new. The RV data are sufficient enough to estimate the orbital periods of three close binaries

Pilot Testing of Assessment of Capacity for Myoelectric Control (ACMC) in Evaluating Myoelectric Hand Function in Chinese Population

Upper limb amputations cause marked functional disability and lower the individual’s self-body image, with severepsychological implications. Many rehabilitation parameters are involved in the successful rehabilitation of upper limbamputations. The aim of this study was to examine the validity and reliability of the Chinese version of Assessment ofCapacity for Myoelectric Control (Chinese-ACMC) in upper limb amputated subjects and with a myo-electric-poweredprosthetic hand.To validate the Chinese version of Assessment of Capacity for Myoelectric Control (Chinese-ACMC) in upper limbamputee subjects (children and adults) with a myo-electric-powered prosthetic hand. A sample of convenience samplingof 22 subjects (11 males, 11 females) with upper limb amputation and myoelectric prosthetic hands were recordedduring a regular clinical visit for ACMC. Each subject was evaluated according to four criteria: (a) Upper Limb Amputationincluding all levels of amputation; (b) No specific pain type – no matter phantom or pain in the stump; (c) With intactcognitive function; (d) Age ranged from 12 to 40 years. With instruction, occupational therapists and prosthetic-orthoticswith at least twenty years’ clinical experience of myoelectric prosthesis training would conduct the 30-items ChineseACMC for each subject. A serial of errand tasks of activities of daily living were designed for evaluation. Individuals’ratings were repeated after 4 weeks. Through test-retest reliability, internal consistency testing, factor analysis, intra andinter factor correlation analysis. A four-factor structure, namely, “Gripping”, “Holding”, “Releasing” and “Coordinating”are identified

The Upper Critical Field Hc2 in Advanced Superconductors with Anisotropic Energy Spectrum

A brief review of works on the microscopic theory of determining the upper critical field in two-band isotropic and anisotropic superconductors is given. The research is based on a set of the Ginzburg-Landau equations for the order parameters in a magnetic field that are studied in terms of the classical approach to a superconducting system in a magnetic field. Two inequivalent energy bands with different topology of Fermi surface cavities overlapping on the Fermi surface are discussed. The cases of the direction of the external magnetic field H\to// the (ab) plane and H\to // the crystallographic c axis are studied. The equations for determining Hc2(ab) and Hc2(c) for a pure superconductor and a superconductor doped with electrons and holes are derived. The analytical solutions to these equations in the vicinity of the superconducting transition temperature (Tc - T<<Tc) and in the vicinity of zero (T<<Tc) are found. The temperature and impurity dependences of the upper critical fields Hc2(ab) and Hc2(c), as well as the anisotropy coefficient \gammaH, are studied. The resulting theory is applied to determine the dependences of the above magnetic characteristics of intermetallic compound MgB2. The theory agrees qualitatively with experimental data.Comment: 24 pages, 6 fi

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

Background: The presence of histone 3 lysine 9 (H3K9) methylation on the mouse inactive X chromosome has been controversial over the last 15 years, and the functional role of H3K9 methylation in X chromosome inactivation in any species has remained largely unexplored. Results: Here we report the first genomic analysis of H3K9 di- and tri-methylation on the inactive X: we find they are enriched at the intergenic, gene poor regions of the inactive X, interspersed between H3K27 tri-methylation domains found in the gene dense regions. Although H3K9 methylation is predominantly non-genic, we find that depletion of H3K9 methylation via depletion of H3K9 methyltransferase Set domain bifurcated 1 (Setdb1) during the establishment of X inactivation, results in failure of silencing for around 150 genes on the inactive X. By contrast, we find a very minor role for Setdb1-mediated H3K9 methylation once X inactivation is fully established. In addition to failed gene silencing, we observed a specific failure to silence X-linked long-terminal repeat class repetitive elements. Conclusions: Here we have shown that H3K9 methylation clearly marks the murine inactive X chromosome. The role of this mark is most apparent during the establishment phase of gene silencing, with a more muted effect on maintenance of the silent state. Based on our data, we hypothesise that Setdb1-mediated H3K9 methylation plays a role in epigenetic silencing of the inactive X via silencing of the repeats, which itself facilitates gene silencing through alterations to the conformation of the whole inactive X chromosome.Andrew Keniry, Linden J. Gearing, Natasha Jansz, Joy Liu, Aliaksei Z. Holik, Peter F. Hickey, Sarah A. Kinkel, Darcy L. Moore, Kelsey Breslin, Kelan Chen, Ruijie Liu, Catherine Phillips, Miha Pakusch, Christine Biben, Julie M. Sheridan, Benjamin T. Kile, Catherine Carmichael, Matthew E. Ritchie, Douglas J. Hilton and Marnie E. Blewit

Nanosized superparamagnetic precipitates in cobalt-doped ZnO

The existence of semiconductors exhibiting long-range ferromagnetic ordering at room temperature still is controversial. One particularly important issue is the presence of secondary magnetic phases such as clusters, segregations, etc... These are often tedious to detect, leading to contradictory interpretations. We show that in our cobalt doped ZnO films grown homoepitaxially on single crystalline ZnO substrates the magnetism unambiguously stems from metallic cobalt nano-inclusions. The magnetic behavior was investigated by SQUID magnetometry, x-ray magnetic circular dichroism, and AC susceptibility measurements. The results were correlated to a detailed microstructural analysis based on high resolution x-ray diffraction, transmission electron microscopy, and electron-spectroscopic imaging. No evidence for carrier mediated ferromagnetic exchange between diluted cobalt moments was found. In contrast, the combined data provide clear evidence that the observed room temperature ferromagnetic-like behavior originates from nanometer sized superparamagnetic metallic cobalt precipitates.Comment: 20 pages, 6 figures; details about background subtraction added to section III. (XMCD

Theory of Coexistence of Superconductivity and Ferroelectricity : A Dynamical Symmetry Model

We propose and investigate a model for the coexistence of Superconductivity (SC) and Ferroelectricity (FE) based on the dynamical symmetries $su(2)$ for the pseudo-spin SC sector, $h(4)$ for the displaced oscillator FE sector, and $su(2) \otimes h(4)$ for the composite system. We assume a minimal symmetry-allowed coupling, and simplify the hamiltonian using a double mean field approximation (DMFA). A variational coherent state (VCS) trial wave-function is used for the ground state: the energy, and the relevant order parameters for SC and FE are obtained. For positive sign of the SC-FE coupling coefficient, a non-zero value of either order parameter can suppress the other (FE polarization suppresses SC and vice versa). This gives some support to "Matthias' Conjecture" [1964], that SC and FE tend to be mutually exclusive. For such a Ferroelectric Superconductor we predict: a) the SC gap $\Delta$ (and $T_c$) will increase with increasing applied pressure when pressure quenches FE as in many ferroelectrics, and b) the FE polarization will increase with increaesing magnetic field up to $H_c$. The last result is equivalent to the prediction of a new type of Magneto-Electric Effect in a coexistent SC-FE material. Some discussion will be given of the relation of these results to the cuprate superconductors.Comment: 46 page

Ferrocenyl-triazolyl-tetrathiafulvalene assemblies: synthesis and electrochemical recognition properties

Cu(I)-catalyzed Huisgen–Meldal–Sharpless type dipolar ‘click’ reactions between azido-tetrathiafulvalene derivatives and ethynylferrocene yield the first examples of ferrocenyl-1,2,3-triazolyl-tetrathiafulvalene assemblies (4a, 4b). The electrochemical behavior of 4a and 4b, which integrate two distinctive redox probes, has been investigated, and their binding ability for various transition-metal cations has been studied by cyclic voltammetry. The contribution of the triazolyl ring in the guest binding process is illustrated by the specific electrochemical recognition of Zn2+ by receptor 4b