74,650 research outputs found
Joint Symbol-Level Precoding and Reflecting Designs for IRS-Enhanced MU-MISO Systems
Intelligent reflecting surfaces (IRSs) have emerged as a revolutionary solution to enhance wireless communications by changing propagation environment in a cost-effective and hardware-efficient fashion. In addition, symbol-level precoding (SLP) has attracted considerable attention recently due to its advantages in converting multiuser interference (MUI) into useful signal energy. Therefore, it is of interest to investigate the employment of IRS in symbol-level precoding systems to exploit MUI in a more effective way by manipulating the multiuser channels. In this article, we focus on joint symbol-level precoding and reflecting designs in IRS-enhanced multiuser multiple-input single-output (MU-MISO) systems. Both power minimization and quality-of-service (QoS) balancing problems are considered. In order to solve the joint optimization problems, we develop an efficient iterative algorithm to decompose them into separate symbol-level precoding and block-level reflecting design problems. An efficient gradient-projection-based algorithm is utilized to design the symbol-level precoding and a Riemannian conjugate gradient (RCG)-based algorithm is employed to solve the reflecting design problem. Simulation results demonstrate the significant performance improvement introduced by the IRS and illustrate the effectiveness of our proposed algorithms
Dynamic Geospatial Spectrum Modelling: Taxonomy, Options and Consequences
Much of the research in Dynamic Spectrum Access (DSA) has focused on opportunistic access in the temporal domain. While this has been quite useful in establishing the technical feasibility of DSA systems, it has missed large sections of the overall DSA problem space. In this paper, we argue that the spatio-temporal operating context of specific environments matters to the selection of the appropriate technology for learning context information. We identify twelve potential operating environments and compare four context awareness approaches (on-board sensing, databases, sensor networks, and cooperative sharing) for these environments. Since our point of view is overall system cost and efficiency, this analysis has utility for those regulators whose objectives are reducing system costs and enhancing system efficiency. We conclude that regulators should pay attention to the operating environment of DSA systems when determining which approaches to context learning to encourage
Clinical evaluation of stretchable and wearable inkjet-printed strain gauge sensor for respiratory rate monitoring at different body postures
Respiratory rate (RR) is a vital sign with continuous, convenient, and accurate measurement which is difficult and still under investigation. The present study investigates and evaluates a stretchable and wearable inkjet-printed strain gauge sensor (IJP) to estimate the RR continuously by detecting the respiratory volume change in the chest area. As the volume change could cause different strain changes at different body postures, this study aims to investigate the accuracy of the IJP RR sensor at selected postures. The evaluation was performed twice on 15 healthy male subjects (mean ± SD of age: 24 ± 1.22 years). The RR was simultaneously measured in breaths per minute (BPM) by the IJP RR sensor and a reference RR sensor (e-Health nasal thermal sensor) at each of the five body postures namely standing, sitting at 90°, Flower’s position at 45°, supine, and right lateral recumbent. There was no significant difference in measured RR between IJP and reference sensors, between two trials, or between different body postures (all p \u3e 0.05). Body posture did not have any significant effect on the difference of RR measurements between IJP and the reference sensors (difference \u3c 0.01 BPM for each measurement in both trials). The IJP sensor could accurately measure the RR at different body postures, which makes it a promising, simple, and user-friendly option for clinical and daily uses
Duality between Feature Selection and Data Clustering
The feature-selection problem is formulated from an information-theoretic
perspective. We show that the problem can be efficiently solved by an extension
of the recently proposed info-clustering paradigm. This reveals the fundamental
duality between feature selection and data clustering,which is a consequence of
the more general duality between the principal partition and the principal
lattice of partitions in combinatorial optimization
On Optimality of Myopic Policy for Restless Multi-armed Bandit Problem with Non i.i.d. Arms and Imperfect Detection
We consider the channel access problem in a multi-channel opportunistic
communication system with imperfect channel sensing, where the state of each
channel evolves as a non independent and identically distributed Markov
process. This problem can be cast into a restless multi-armed bandit (RMAB)
problem that is intractable for its exponential computation complexity. A
natural alternative is to consider the easily implementable myopic policy that
maximizes the immediate reward but ignores the impact of the current strategy
on the future reward. In particular, we develop three axioms characterizing a
family of generic and practically important functions termed as -regular
functions which includes a wide spectrum of utility functions in engineering.
By pursuing a mathematical analysis based on the axioms, we establish a set of
closed-form structural conditions for the optimality of myopic policy.Comment: Second version, 16 page
On Optimality of Myopic Sensing Policy with Imperfect Sensing in Multi-channel Opportunistic Access
We consider the channel access problem under imperfect sensing of channel
state in a multi-channel opportunistic communication system, where the state of
each channel evolves as an independent and identically distributed Markov
process. The considered problem can be cast into a restless multi-armed bandit
(RMAB) problem that is of fundamental importance in decision theory. It is
well-known that solving the RMAB problem is PSPACE-hard, with the optimal
policy usually intractable due to the exponential computation complexity. A
natural alternative is to consider the easily implementable myopic policy that
maximizes the immediate reward but ignores the impact of the current strategy
on the future reward. In this paper, we perform an analytical study on the
optimality of the myopic policy under imperfect sensing for the considered RMAB
problem. Specifically, for a family of generic and practically important
utility functions, we establish the closed-form conditions under which the
myopic policy is guaranteed to be optimal even under imperfect sensing. Despite
our focus on the opportunistic channel access, the obtained results are generic
in nature and are widely applicable in a wide range of engineering domains.Comment: 21 pages regular pape
Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways
Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of neurodevelopmental migratory pathways, possibly triggered by febrile seizures. This study aims to compare the proteomes of basal and dispersed granule cells in the hippocampus of eight MTLE patients with GCD to identify proteins that may mediate GCD in MTLE.
Quantitative proteomics identified 1882 proteins, of which 29% were found in basal granule cells only, 17% in dispersed only and 54% in both samples. Bioinformatics analyses revealed upregulated proteins in dispersed samples were involved in developmental cellular migratory processes, including cytoskeletal remodelling, axon guidance and signalling by Ras homologous (Rho) family of GTPases (P<0.01). The expression of two Rho GTPases, RhoA and Rac1, was subsequently explored in immunohistochemical and in situ hybridisation studies involving eighteen MTLE cases with or without GCD, and three normal post mortem cases. In cases with GCD, most dispersed granule cells in the outer-granular and molecular layers have an elongated soma and bipolar processes, with intense RhoA immunolabelling at opposite poles of the cell soma, while most granule cells in the basal granule cell layer were devoid of RhoA. A higher density and percentage of cells expressing RhoA was observed in cases with GCD than without GCD (P<0.004). In GCD cases, the density and percentage of cells expressing RhoA was significantly higher in the inner molecular layer than granule cell layer (P<0.026), supporting proteomic findings. In situ hybridisation studies using probes against RHOA and RAC1 mRNAs revealed fine peri- and nuclear puncta in granule cells of all cases. The density of cells expressing RHOA mRNAs were significantly higher in the inner molecular layer of cases with GCD than without GCD(P=0.05). In summary, our study has found limited evidence for ongoing adult neurogenesis in the hippocampus of patients with MTLE, but evidence of differential dysmaturation between dispersed and basal granule cells has been demonstrated, and elevated expression of Rho GTPases in dispersed granule cells may contribute to the pathomechanisms underpinning GCD in MTLE
Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease
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