CLOFFAR - update 3 - supplement to Checklist of the Freshwater Fishes of Argentina

In May 2016 we have published the second update to CLOFFAR and in these few months a total of 22 changes have summed up. The total number of fishes known from the freshwaters of Argentina has increased to 538, caused by one new Hoplias and 13 first records. Four new combinations and four synonymizations do not have influence on the total count. The paper of most importance in quantity without doubt is the one of Casciotta et al. on their findings in the Iguazú National Park, unfortunately also including two first records of exotic introduced species, Clarias gariepinus and Geophagus brasiliensis. Clarias gariepinus was included in this update against our standard to only recognize records which have been published based on voucher material. In this case the determination could undoubtfully be done based on a photo and this invasive species has been reported before from the lower Iguazú river in Brazil in 2012 already. The confirmation of Crenicichla iguassuensis has undergone some see-saw development in the past and the respective remarks can be found when following the link. Also another publication needs to be commented on: The synonymyzations of four rivulids by Calviño has been published as an isolated statement beyond any systematical context. Nevertheless, it has been formally published and in some of these cases the probability of being synonyms had been stated previously by other authors. Future will show the resilience and acceptance of those synonymizations. The paper of Ortí et al. dates from 2008 and was simply not known to us before and thus, the new combination of Myloplus tiete from Myleus is only included now, eigth years later.Fil: Koerber, Stefan. Gesellschaft für Ichthyolgie; AlemaniaFil: Litz, Thomas O.. Gesellschaft für Ichthyolgie; AlemaniaFil: Mirande, Juan Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Tucumán. Unidad Ejecutora Lillo; Argentin

CLOFFAR - update 1 - supplement to Checklist of the Freshwater Fishes of Argentina

Despite the fact that this first update of CLOFFAR contains 15 changes, the number of species has increased by only 4. The main driver for the recent changes is the paper of Thomaz et al., proposing 8 new combinations for stevardiine characiforms. In addition, 2 new Crenicichla and first records for a tachuela, a pejerrey, and a heptapterid have been published. The latter also resulted in the negative account for another heptapterid, erroneously determined before, increasing the number of freshwater fish species known from Argentina to 519.Fil: Koerber, Stefan.Fil: Litz, Thomas O..Fil: Mirande, Juan Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Miguel Lillo; Argentin

Proceedings of the 3rd Biennial Conference of the Society for Implementation Research Collaboration (SIRC) 2015: advancing efficient methodologies through community partnerships and team science

It is well documented that the majority of adults, children and families in need of evidence-based behavioral health interventionsi do not receive them [1, 2] and that few robust empirically supported methods for implementing evidence-based practices (EBPs) exist. The Society for Implementation Research Collaboration (SIRC) represents a burgeoning effort to advance the innovation and rigor of implementation research and is uniquely focused on bringing together researchers and stakeholders committed to evaluating the implementation of complex evidence-based behavioral health interventions. Through its diverse activities and membership, SIRC aims to foster the promise of implementation research to better serve the behavioral health needs of the population by identifying rigorous, relevant, and efficient strategies that successfully transfer scientific evidence to clinical knowledge for use in real world settings [3]. SIRC began as a National Institute of Mental Health (NIMH)-funded conference series in 2010 (previously titled the “Seattle Implementation Research Conference”; $150,000 USD for 3 conferences in 2011, 2013, and 2015) with the recognition that there were multiple researchers and stakeholdersi working in parallel on innovative implementation science projects in behavioral health, but that formal channels for communicating and collaborating with one another were relatively unavailable. There was a significant need for a forum within which implementation researchers and stakeholders could learn from one another, refine approaches to science and practice, and develop an implementation research agenda using common measures, methods, and research principles to improve both the frequency and quality with which behavioral health treatment implementation is evaluated. SIRC’s membership growth is a testament to this identified need with more than 1000 members from 2011 to the present.ii SIRC’s primary objectives are to: (1) foster communication and collaboration across diverse groups, including implementation researchers, intermediariesi, as well as community stakeholders (SIRC uses the term “EBP champions” for these groups) – and to do so across multiple career levels (e.g., students, early career faculty, established investigators); and (2) enhance and disseminate rigorous measures and methodologies for implementing EBPs and evaluating EBP implementation efforts. These objectives are well aligned with Glasgow and colleagues’ [4] five core tenets deemed critical for advancing implementation science: collaboration, efficiency and speed, rigor and relevance, improved capacity, and cumulative knowledge. SIRC advances these objectives and tenets through in-person conferences, which bring together multidisciplinary implementation researchers and those implementing evidence-based behavioral health interventions in the community to share their work and create professional connections and collaborations

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

BACKGROUND: Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes. METHODS: We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization. RESULTS: During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events. CONCLUSIONS: Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)

Ectrepopterus Fowler 1943

<i>Ectrepopterus</i> Fowler 1943 <p> <i>Ectrepopterus</i> Fowler 1943:313 (subgenus of <i>Megalamphodus</i>; type species by original designation and monotypy: <i>Megalamphodus uruguayensis</i>). Géry 1972:14 (redescription of the type species; new diagnosis for the subgenus). Géry 1977:586 (synonym of <i>Megalamphodus</i>). Weitzman and Palmer 1997:234 (synonym of <i>Hyphessobrycon</i>).</p> <p> <b>Diagnosis.</b> The following unambiguous apomorphies obtained through equal weighting analysis diagnose <i>Ectrepopterus</i> (ordered according to their consistency indexes). Characters 62, 67, 168, and 310 were also found as unambiguous autapomorphies of <i>Ectrepopterus</i> in the implied weighting analysis.</p> <p> - <b>(Ch. 168:2; ci = 0.33)</b> Foramen in posterior region of metapterygoid that serves as passage for the <i>ramus mandibularis</i> of the <i>trigeminus</i> nerve forms an incomplete arch, bordered posteriorly by the hyomandibula (Fig. 2). This foramen is situated entirely within the metapterygoid among characid fishes lacking a supraorbital. The condition found in <i>Ectrepopterus</i> is apomorphic, and a reversal, since the foramen opening posteriorly is found in several basal lineages of the Characidae (<i>e</i>. <i>g</i>. <i>Brycon</i> Müller and Troschel 1844, <i>Bryconops</i> Kner 1858, and <i>Iguanodectes</i> Cope 1872; see Mirande 2010). This condition was found homoplastically in <i>Bryconamericus scleroparius</i> (Regan 1908) and in <i>Pseudocorynopoma doriae</i> Perugia 1891.</p> <p> - <b>(Ch. 310:1; ci = 0.10)</b> Pectoral-fin rays bearing hooks. Although the presence of hooks in the fin rays is a condition shared by most characid fishes (Malabarba and Weitzman 2003), its presence in the pectoral fin rays is not usual and was found by parsimony as diagnostic for <i>Ectrepopterus</i>. It was found homoplastic in <i>Astyanax</i> cf. <i>asuncionensis</i> Géry 1972, <i>A. chico</i> Casciotta and Almirón 2004, <i>A</i>. <i>lineatus</i> (Perugia 1891), <i>A. troya</i> Azpelicueta, Casciotta and Almirón 2002, <i>Bario steindachneri</i> (Eigenmann 1893), <i>Bryconamericus iheringii</i> (Boulenger 1887), <i>B</i>. <i>rubropictus</i> (Berg 1901), <i>B</i>. <i>thomasi</i> Fowler 1940, <i>Hyphessobrycon luetkenii</i> (Boulenger 1887), <i>H</i>. <i>socolofi</i> Weitzman 1977, and <i>Nematocharax venustus</i> Weitzman, Menezes and Britski 1986 (Mirande 2010).</p> <p> - <b>(Ch. 62:2; ci = 0.06)</b> Posterior margin of second infraorbital posteroventrally oblique and second infraorbital ventrally bordering anterior region of third infraorbital (Fig. 3). This condition is usually associated with a long maxilla, and is found homoplastic in <i>Exodon paradoxus</i> Müller and Troschel 1844, <i>Hollandichthys multifasciatus</i> (Eigenmann and Norris 1900), <i>Oligosarcus</i> spp., and several genera of the Characinae.</p> <p> - <b>(Ch. 67:0; ci = 0.03)</b> Fourth infraorbital (Fig. 3) more developed longitudinally than dorsoventrally (<i>versus</i> longer dorsoventrally than longitudinally). Although apomorphic for <i>Ectrepopterus</i>, this character is broadly distributed among Characidae.</p> <p> - <b>(Ch. 104:1; ci = 0.03)</b> Ascending process of premaxilla reaching just anterior end of nasal (<i>versus</i> reaching at least one-third of length of nasal). Although apomorphic for <i>Ectrepopterus</i>, this character is broadly distributed among Characidae.</p> <p> - <b>(Ch. 91:1; ci = 0.02)</b> Lateral line interrupted (<i>versus</i> complete). Although highly variable in Characidae, this character was recovered as one of the autapomorphies for <i>Ectrepopterus</i>.</p>Published as part of <i>Malabarba, Luiz R., Bertaco, Vinicius A., Carvalho, Fernando R. & Litz, Thomas O., 2012, Revalidation of the genus Ectrepopterus Fowler (Teleostei: Characiformes), with the redescription of its type species, E. uruguayensis, pp. 47-60 in Zootaxa 3204</i> on pages 49-50, DOI: <a href="http://zenodo.org/record/210066">10.5281/zenodo.210066</a&gt