357 research outputs found
Dirac Surface States and Nature of Superconductivity in Noncentrosymmetric BiPd
In non-magnetic bulk materials, inversion symmetry protects the spin
degeneracy. If the bulk crystal structure lacks a centre of inversion, however,
spin-orbit interactions lift the spin degeneracy, leading to a Rashba metal
whose Fermi surfaces exhibit an intricate spin texture. In superconducting
Rashba metals a pairing wavefunction constructed from these complex spin
structures will generally contain both singlet and triplet character. Here we
examine the possible triplet components of the order parameter in
noncentrosymmetric BiPd, combining for the first time in a noncentrosymmetric
superconductor macroscopic characterization, atomic-scale ultra-low-temperature
scanning tunnelling spectroscopy, and relativistic first-principles
calculations. While the superconducting state of BiPd appears topologically
trivial, consistent with Bardeen-Cooper-Schrieffer theory with an order
parameter governed by a single isotropic s-wave gap, we show that the material
exhibits Dirac-cone surface states with a helical spin polarization.Comment: replaced by published versio
Influence of continental roots and asthenosphere on plate‐mantle coupling
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94652/1/grl21239.pd
Modification of the lithospheric stress field by lateral variations in plate‐mantle coupling
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95471/1/grl26475.pd
Modification of the lithospheric stress field by lateral variations in plate-mantle coupling
[1] The presence of deeply penetrating continental roots may locally increase the magnitude of basal shear tractions by up to a factor of 4 compared to a layered viscosity structure. Here we examine how these increases in mantlelithosphere coupling influence stress patterns in the overlying elastic lithosphere. By coupling a mantle flow model to a model for the elastic lithosphere, we show that the amplification of mantle tractions beneath cratons increases elastic stress magnitudes by at most a factor of only 1.5 in a pattern not correlated to local basal traction changes. This disconnect is explained by the transmission of elastic stresses across large distances, which makes them sensitive to regionally-averaged changes in basal tractions, but not local variations. Our results highlight the importance of regional variations in lithospheric strength, which could allow stress patterns to more closely match regional changes in basal shear. Citation: Naliboff, J. B., C. P. Conrad, and C. Lithgow-Bertelloni (2009), Modification of the lithospheric stress field by lateral variations in plate-mantle coupling, Geophys. Res. Lett., 36, L22307
Iceland, the Farallon slab, and dynamic topography of the North Atlantic
ABSTRACT Upwelling or downwelling flow in Earth's mantle is thought to elevate or depress Earth's surface on a continental scale. Direct observation of this ''dynamic topography'' on the seafloor, however, has remained elusive because it is obscured by isostatically supported topography caused by near-surface density variations. We calculate the nonisostatic topography of the North Atlantic by correcting seafloor depths for lithospheric cooling and sediment loading, and find that seafloor west of the Mid-Atlantic Ridge is an average of 0.5 km deeper than it is to the east. We are able to reproduce this basic observation in a model of mantle flow driven by tomographically inferred mantle densities. This model shows that the Farallon slab, currently in the lower mantle beneath the east coast of North America, induces downwelling flow that deepens the western North Atlantic relative to the east. Our model also predicts dynamic support of observed topographic highs near Iceland and the Azores, but suggests that the Icelandic high is due to local upper-mantle upwelling, while the Azores high is part of a plate-scale lower-mantle upwelling to the south. An anomalously deep area off the coast of Nova Scotia may be associated with the downwelling component of edge-driven convection at the continental boundary. Thus, several of the seafloor's topographic features can only be understood in terms of dynamic support from flow in Earth's mantle
Protein secretion and outer membrane assembly in Alphaproteobacteria
The assembly of β-barrel proteins into membranes is a fundamental process that is essential in Gram-negative bacteria, mitochondria and plastids. Our understanding of the mechanism of β-barrel assembly is progressing from studies carried out in Escherichia coli and Neisseria meningitidis. Comparative sequence analysis suggests that while many components mediating β-barrel protein assembly are conserved in all groups of bacteria with outer membranes, some components are notably absent. The Alphaproteobacteria in particular seem prone to gene loss and show the presence or absence of specific components mediating the assembly of β-barrels: some components of the pathway appear to be missing from whole groups of bacteria (e.g. Skp, YfgL and NlpB), other proteins are conserved but are missing characteristic domains (e.g. SurA). This comparative analysis is also revealing important structural signatures that are vague unless multiple members from a protein family are considered as a group (e.g. tetratricopeptide repeat (TPR) motifs in YfiO, β-propeller signatures in YfgL). Given that the process of the β-barrel assembly is conserved, analysis of outer membrane biogenesis in Alphaproteobacteria, the bacterial group that gave rise to mitochondria, also promises insight into the assembly of β-barrel proteins in eukaryotes
Reconstruction of gross avian genome structure, organization and evolution suggests that the chicken lineage most closely resembles the dinosaur avian ancestor
Background
The availability of multiple avian genome sequence assemblies greatly improves our ability to define overall genome organization and reconstruct evolutionary changes. In birds, this has previously been impeded by a near intractable karyotype and relied almost exclusively on comparative molecular cytogenetics of only the largest chromosomes. Here, novel whole genome sequence information from 21 avian genome sequences (most newly assembled) made available on an interactive browser (Evolution Highway) was analyzed.
Results
Focusing on the six best-assembled genomes allowed us to assemble a putative karyotype of the dinosaur ancestor for each chromosome. Reconstructing evolutionary events that led to each species' genome organization, we determined that the fastest rate of change occurred in the zebra finch and budgerigar, consistent with rapid speciation events in the Passeriformes and Psittaciformes. Intra- and interchromosomal changes were explained most parsimoniously by a series of inversions and translocations respectively, with breakpoint reuse being commonplace. Analyzing chicken and zebra finch, we found little evidence to support the hypothesis of an association of evolutionary breakpoint regions with recombination hotspots but some evidence to support the hypothesis that microchromosomes largely represent conserved blocks of synteny in the majority of the 21 species analyzed. All but one species showed the expected number of microchromosomal rearrangements predicted by the haploid chromosome count. Ostrich, however, appeared to retain an overall karyotype structure of 2n = 80 despite undergoing a large number (26) of hitherto un-described interchromosomal changes.
Conclusions
Results suggest that mechanisms exist to preserve a static overall avian karyotype/genomic structure, including the microchromosomes, with widespread interchromosomal change occurring rarely (e.g. in ostrich and budgerigar lineages). Of the species analyzed, the chicken lineage appeared to have undergone the fewest changes compared to the dinosaur ancestor
Plume generation in natural thermal convection at high Rayleigh and Prandtl numbers
We study natural thermal convection of a fluid (corn syrup) with a large Prandtl number (10(3)-10(7)) and temperature-dependent viscosity. The experimental tank (1 x 1 x 0.3 m) is heated from below with insulating top and side boundaries, so that the fluid experiences secular heating as experiments proceed. This setup allows a focused study of thermal plumes from the bottom boundary layer over a range of Rayleigh numbers relevant to convective plumes in the deep interior of the Earth's mantle. The effective value of Ra, based on the viscosity of the fluid at the interior temperature, varies from 10(5) at the beginning to almost 10(8) toward the end of the experiments. Thermals (plumes) from the lower boundary layer are trailed by continuous conduits with long residence times. Plumes dominate flow in the tank, although there is a weaker large-scale circulation induced by material cooling at the imperfectly insulating top and sidewalls. At large Ra convection is extremely time-dependent and exhibits episodic bursts of plumes, separated by periods of quiescence. This bursting behaviour probably results from the inability of the structure of the thermal boundary layer and its instabilities to keep pace with the rate of secular change in the value of Ra. The frequency of plumes increases and their size decreases with increasing Ra, and we characterize these changes via in situ thermocouple measurements, shadowgraph videos, and videos of liquid crystal films recorded during several experiments. A scaling analysis predicts observed changes in plume head and tail radii with increasing Ra. Since inertial effects are largely absent no transition to 'hard' thermal turbulence is observed, in contrast to a previous conclusion from numerical calculations at similar Rayleigh numbers. We suggest that bursting behaviour similar to that observed may occur in the Earth's mantle as it undergoes secular cooling on the billion-year time scale
Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB is also targeted to host mitochondria and regulates apoptosis pathways to promote infections. How PorB traffics from the outer membrane of N. gonorrhoeae to mitochondria and whether it modulates innate immune cells, such as macrophages, remains unclear. Here, we show that N. gonorrhoeae secretes PorB via outer membrane vesicles (OMVs). Purified OMVs contained primarily outer membrane proteins including oligomeric PorB. The porin was targeted to mitochondria of macrophages after exposure to purified OMVs and wild type N. gonorrhoeae. This was associated with loss of mitochondrial membrane potential, release of cytochrome c, activation of apoptotic caspases and cell death in a time-dependent manner. Consistent with this, OMV-induced macrophage death was prevented with the pan-caspase inhibitor, Q-VD-PH. This shows that N. gonorrhoeae utilizes OMVs to target PorB to mitochondria and to induce apoptosis in macrophages, thus affecting innate immunity
The temporal evolution of plate driving forces: Importance of “slab suction” versus “slab pull” during the Cenozoic
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95131/1/jgrb14092.pd
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