691 research outputs found
Developing a data sharing framework: a case study
Purpose:
The purpose of the research project was to examine the process of developing a data sharing framework between different public sector organizations.
Design / methodology / approach:
A two year case study of a data sharing project between a UK fire and rescue service, local council, NHS primary care trust and a police force was undertaken.
Findings:
It is important to carefully determine the requirements for data sharing, to establish data sharing agreements, to have secure arrangements for data sharing, and to ensure compliance with data protection legislation.
Research limitations / implications:
Data sharing between public sector organizations can operate effectively if appropriate care is taken when creating data sharing agreements between partner organizations.
Practical implications:
Data sharing can assist in reducing duplication of effort between public sector organizations, and can reduce costs and enable more co-ordinated provision of public services.
Social implications:
Data sharing can assist in identifying citizens who might otherwise have been overlooked to relevant organizations. Data sharing can also assist in reducing risks associated with individuals and promote more independent living.
Originality / value:
The detailed analysis of a data sharing case study identified the need for a systematic data sharing framework. Such a framework is proposed and illustrated with practical examples of specification, implementation and evaluation.
Key words: Data sharing framework public sector management data protection legislatio
EP-1423: Hypofractionated radiotherapy for complicated bone metastases in patients with poor performance
Typological classification of clayey raw materials for ceramics manufacture, in the Tábua region (central Portugal)
Mapping of clay resources in the Cenozoic deposits of the Tábua region (central Portugal) has been carried out, together with the chemical, mineralogical and
technological characterization of seventeen clay samples. The study was undertaken to relate the lithostratigraphic units and the typology of raw materials
with regard to the manufacture of ceramics. The sedimentary succession comprises two units with different suitability for the manufacture of ceramics: an
upper unit, with clays that present technological restrictions; and a lower unit with a much greater potential. A small set of parameters has been identified
which differentiate the typological units. These parameters allow a realistic estimation to be made of the ceramic properties of any clay layer sampled in the
study area. It is anticipated that with minor field work and sampling, the typological column can also be used in adjacent areas
Neoadjuvant use of Imiquimod Before Surgery in Extramammary Paget’s Disease
A doença de Paget extramamária (DPEM) é uma neoplasia maligna cutânea, rara, observada principalmente em mulheres caucasianas pós-menopausa. A cirurgia é o tratamento mais comum. No entanto, no que diz respeito à DPEM vulvar, o seu tratamento cirúrgico passa frequentemente por cirurgia radical, que pode ser mutilante e levar à perda de feminilidade. Recentes avanços terapêuticos têm incluído abordagem médica e multimodal médico-cirúrgico, permitindo uma maior preservação da anatomia genital e subsequente diminuição da morbilidade. Neste sentido, imiquimod tem sido utilizado, off-label, como monoterapia ou terapêutica adjuvante na DPEM.Relatamos o caso de uma mulher com DPEM extenso na área anogenital submetida a resseção cirúrgica complementada com reconstrução plástica e precedida de tratamento médico com imiquimod. O imiquimod neoadjuvante permitiu uma citorredução significativa da área tumoral, minimizando a radicalidade cirúrgica, mantendo a função local e a morfologia.Extramammary Paget's disease (EMPD) is a distinct form of a rare malignant skin neoplasm, primarily seen in postmenopausal Caucasian women. Surgery is the most common treatment. However, concerning vulvar EMPD, radical surgery can be mutilating and leads to loss of femininity. Recent therapeutic development has included medical and medical-surgical approaches, allowing better preservation of genital anatomy with subsequent reduced morbidity. Accordingly, off-label use of imiquimod has been reported as a monotherapy or adjuvant therapy in EMPD.We report the case of a woman with extensive EMPD in the anogenital area, submitted to surgical resection complemented with plastic reconstruction and preceded by imiquimod medical treatment. Neoadjuvant imiquimod induced a significant cytoreduction of the tumor area, minimizing surgical radicality and maintaining local function and morpholog
GeoPAC: Sistema de Monitoramento de Obras do PAC.
O objetivo deste documento é descrever o sistema GeoPAC. São apresentados seu histórico de desenvolvimento, sua arquitetura de software, suas principais funcionalidades e alguns exemplos de análises de contexto territorial elaboradas pela Embrapa, a partir dos dados espaciais dos empreendimentos do PAC catalogados pelo sistema. O GeoPAC está disponível remotamente para o Ministério do Planejamento, Orçamento e Gestão (MPOG) e é fornece diversos parâmetros e indicadores utilizados no acompanhamento territorial dos empreendimentos do PAC.bitstream/item/98227/1/20140225-GeoPAC2.pd
Identification and definition of novel clinical phenotypes of breast cancer through consensus derived from automated clustering methods
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