Re-presenting Italy in Australia through Theatre and Music, 1972-2002

This chapter is based on a conversation with Antonio Comin at his home in Norwood, South Australia, on 2 March 2009, edited and annotated by Linda Barwick. Antonio Comin (born Cornuda, Italy, in 1933) migrated with his family to Australia in 1936. A graduate of the University of Sydney and the Università degli Studi di Firenze, he taught at the universities of Sydney, Melbourne and British Columbia (Vancouver, Canada) before joining Flinders University in 1970 as foundation Professor of Italian. Until his retirement in 1996, his main teaching and research areas were Italian language, dialectology and traditional culture. Comin’s mission to establish and promote in South Australia the understanding of Italian language and culture was undertaken in large part through various theatrical productions he devised and mounted from 1976–2007, which increasingly incorporated his own writing as well as musical components including Italian traditional song. The Italian Folk Ensemble, a musical group formed as a result of Comin’s activities, has been active in community music performances as well as theatre productions since 1978, and after a hiatus of some years various members including Comin reformed in 2003 under the name “Gruppo La Questua”. Linda Barwick studied under Comin in the Italian Discipline in the 1970s and 1980s, and participated in the Italian Folk Ensemble and some of the theatrical productions mentioned here. After covering background about Comin’s early life and cultural formation in Australia and Italy, the chapter presents Comin’s commentary on the various theatrical productions he conceived and directed. Unless otherwise indicated, the speaker is Comin. Commentary in footnotes is by Barwick, who also compiled the figures and appendices.Australian Research Counci

A role for Separase in telomere protection

Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity and are assembled independently of the sequence. Fly telomeres are protected by the terminin complex that localizes and functions exclusively at telomeres and by non-terminin proteins that do not serve telomere-specific functions. We show that mutations in the Drosophila Separase encoding gene Sse lead not only to endoreduplication but also telomeric fusions (TFs), suggesting a role for Sse in telomere capping. We demonstrate that Separase binds terminin proteins and HP1, and that it is enriched at telomeres. Furthermore, we show that loss of Sse strongly reduces HP1 levels, and that HP1 overexpression in Sse mutants suppresses TFs, suggesting that TFs are caused by a HP1 diminution. Finally, we find that siRNA-induced depletion of ESPL1, the Sse human orthologue, causes telomere dysfunction and HP1 level reduction in primary fibroblasts, highlighting a conserved role of Separase in telomere protection

A long-term "memory" of HIF induction in response to chronic mild decreased oxygen after oxygen normalization

Background Endothelial dysfunction (ED) is functionally characterized by decreased vasorelaxation, increased thrombosis, increased inflammation, and altered angiogenic potential, has been intimately associated with the progression and severity of cardiovascular disease. Patients with compromised cardiac function oftentimes have a state of chronic mild decreased oxygen at the level of the vasculature and organs, which has been shown to exacerbate ED. Hypoxia inducible factor (HIF) is a transcription factor complex shown to be the master regulator of the cellular response to decreased oxygen levels and many HIF target genes have been shown to be associated with ED. Methods Human endothelial and aortic smooth muscle cells were exposed either to A) normoxia (21% O2) for three weeks, or to B) mild decreased oxygen (15% O2) for three weeks to mimic blood oxygen levels in patients with heart failure, or to C) mild decreased oxygen for two weeks followed by one week of normoxia ("memory" treatment). Levels of HIF signaling genes (HIF-1α, HIF-2α, VEGF, BNIP3, GLUT-1, PAI-1 and iNOS) were measured both at the protein and mRNA levels. Results It was found that chronic exposure to mild decreased oxygen resulted in significantly increased HIF signaling. There was also a "memory" of HIF-1α and HIF target gene induction when oxygen levels were normalized for one week, and this "memory" could be interrupted by adding a small molecule HIF inhibitor to the last week of normalized oxygen. Finally, levels of ubiquitylated HIF-1α were reduced in response to chronic mild decreased oxygen and were not full restored after oxygen normalization. Conclusion These data suggest that HIF signaling may be contributing to the pathogenesis of endothelial dysfunction and that normalization of oxygen levels may not be enough to reduce vascular stress

A systematic literature review on the development and use of mobile learning (web) apps by early adopters

Surveys in mobile learning developed so far have analysed in a global way the effects on the usage of mobile devices by means of general apps or apps already developed. However, more and more teachers are developing their own apps to address issues not covered by existing m-learning apps. In this article, by means of a systematic literature review that covers 62 publications placed in the hype of teacher-created m-learning apps (between 2012 and 2017, the early adopters) and the usage of 71 apps, we have analysed the use of specific m-learning apps. Our results show that apps have been used both out of the classroom to develop autonomous learning or field trips, and in the classroom, mainly, for collaborative activities. The experiences analysed only develop low level outcomes and the results obtained are positive improving learning, learning performance, and attitude. As a conclusion of this study is that the results obtained with specific developed apps are quite similar to previous general surveys and that the development of long-term experiences are required to determine the real effect of instructional designs based on mobile devices. These designs should also be oriented to evaluate high level skills and take advantage of mobile features of mobile devices to develop learning activities that be made anytime at anyplace and taking into account context and realistic situations. Furthermore, it is considered relevant the study of the role of educational mobile development frameworks in facilitating teachers the development of m-learning apps

The protoplanetary disk of FT Tauri: multi-wavelength data analysis and modeling

Investigating the evolution of protoplanetary disks is crucial for our understanding of star and planet formation. Several theoretical and observational studies have been performed in the last decades to advance this knowledge. FT Tauri is a young star in the Taurus star forming region that was included in a number of spectroscopic and photometric surveys. We investigate the properties of the star, the circumstellar disk, and the accretion and ejection processes and propose a consistent gas and dust model also as a reference for future observational studies. We performed a multi-wavelength data analysis to derive the basic stellar and disk properties, as well as mass accretion/outflow rate from TNG-Dolores, WHT-Liris, NOT-Notcam, Keck-Nirspec, and Herschel-Pacs spectra. From the literature, we compiled a complete Spectral Energy Distribution. We then performed detailed disk modeling using the MCFOST and ProDiMo codes. Multi-wavelengths spectroscopic and photometric measurements were compared with the reddened predictions of the codes in order to constrain the disk properties. This object can serve as a benchmark for primordial disks with significant mass accretion rate, high gas content and typical size.Comment: 16 pages, 9 figures, accepted for publication in A&

Perfilhamento em Capim-bermuda cv. Tifton 85 em resposta a doses e ao momento de aplicação do nitrogênio após o corte

A adubação nitrogenada é fator determinante na produtividade das pastagens, pois aumenta a produção de massa e está associada à fisiologia de crescimento das plantas forrageiras. Um experimento foi conduzido com a gramínea Tifton 85 (Cynodon spp.), em casa-de-vegetação num solo Neossolo Quartzarênico, com o objetivo de avaliar a influência de doses e momentos de aplicação de nitrogênio após o corte no perfilhamento desta planta forrageira. Foram definidas quatro doses e dois momentos de aplicação de nitrogênio após o corte, em esquema fatorial 4 x 2, no delineamento experimental de blocos completos ao acaso, com quatro repetições. As doses de nitrogênio foram de 0, 80, 160 e 240 mg kg-1 de solo e os dois momentos de aplicação de nitrogênio foram imediatamente após o corte das plantas e após sete dias. As avaliações foram conduzidas durante dois períodos de crescimentos, com as plantas atingindo 39 e 41 dias de idade. Houve efeito das doses de nitrogênio no número inicial de perfilhos no segundo crescimento, e no número de perfilhos surgidos e no número final de perfilhos nos dois períodos avaliados. O peso dos perfilhos individuais teve incrementos até as doses de nitrogênio de 201 e 185 mg kg-1 de solo, no primeiro e segundo cortes, respectivamente. Foram obtidos os coeficientes de correlação de 0,92 e 0,94 entre o número final de perfilhos e produção de massa seca da parte aérea, para o primeiro e segundo crescimentos, respectivamente. A taxa de aparecimento de perfilhos foi influenciada pelas doses e momentos de aplicação de nitrogênio após o corte, sendo estes efeitos independentes no primeiro e interativos no segundo crescimento, para cada período de avaliação.Nitrogen fertilization is determinant for pasture productivity, as it results in increasing forage yield and is associated with the growth physiology of forage plants. An experiment was carried out in a greenhouse to evaluate the effects of nitrogen rates and times of application after cutting on Tifton 85 Bermuda grass (Cynodon spp.) tillering. Plants were grown in a Typic Quartzipsamment soil and nitrogen rates were 0, 80, 160 and 240 mg kg-1 of soil; times of application were immediately after and seven days after cutting. A 4 x 2 factorial experiment was set in a completely randomized block design (n= 4). Plants were evaluated in two sequential growth periods - 39 and 41 days. Nitrogen rates affected tiller density, considering the initial number of tillers in the second growth and the emerged and final number of tillers at the end of the growth periods. Tiller weight increased up to the nitrogen rate of 201 and 185 mg kg-1 of soil in the first and second growth periods, and the correlation coefficients between the final number of tillers and dry matter yields in the top part of the plant for these periods were 0.92 and 0.94, respectively. The rate of tiller development, evaluated in each of the seven-day periods, was affected by nitrogen rates and time of application. There was an effect of rates and time of application in the first and a significant interaction between rates and time in the second growth period