Monitoria acadêmica em enfermagem: uma revisão de literatura / Academic monitoring in nursing: a literature review

A partir da experiência vivenciada enquanto discentes no programa de monitoria, surgiu a curiosidade de uma revisão da literatura sobre o programa e suas contribuições na formação acadêmico-profissional. Para tanto, buscou-se subsídios para conhecer as propostas do programa de monitoria na graduação e compreender os desafios e fragilidades desta atividade. A pesquisa trata-se de uma revisão da literatura. A busca de periódicos ocorreu de agosto a dezembro de 2015, através dos bancos de dados da Scielo, Scholar e BVS. Os discentes da educação superior poderão ser aproveitados em tarefas de ensino e pesquisa pelas respectivas instituições, exercendo funções de monitoria, de acordo com seu rendimento e seu plano de estudos. De tal maneira o programa nas Instituições de Ensino Superior (IES) tem se desenvolvido com um foco didático e torna um pré-requisito para seleção a afinidade do aluno com a disciplina de escolha, o rendimento acadêmico acima da média e o interesse pela carreira de docência. O estudo nos mostra a magnitude do programa de monitoria acadêmica na graduação em enfermagem. A monitoria impacta tanto na relação interpessoal e conhecimentos teóricos quanto em habilidades motoras inerentes a profissão

Antioxidant, antimicrobial and immunostimulant properties of saline extract from Caesalpinia pulcherrima (L.) Swartz (Fabaceae) leaves

281-289Caesalpinia pulcherrima (L.) Swartz is a species that originates in India and Central America and is widely distributed in the world. This plant presents important biological properties, due to the presence of some secondary medicinal metabolites, such as tannins, glycosides, flavonoids and diterpenes. In folk medicine, C. pulcherrima is used in different diseases as bronchitis, asthma, infections, wounds and eye irritations. The aim of this study was to perform a phytochemical screening and evaluate which biological properties the saline extract of leaves from C. pulcherrima have against microorganisms and animal cells. Results showed that 15 majority compounds could be found in saline extract distributed among phenol, coumarin and quercetin groups.Saline extract of leaves from C. pulcherrima also showed good results in antioxidant test and showed significant antifungal property against Candida strains. Moreover, the saline extract did not showed cytotoxicity against mice splenocytes and promoted proliferation in these cells. These results may be predictive for future studies using the saline extract from C. pulcherrima leaves as cell stimulant agent in a pharmaceutical phytotherapic formulation used in cicatricial and in vitro immunostimulant assays

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Implementação das práticas obstétricas preconizadas pelo programa de humanização no pré natal e nascimento em uma maternidade de risco habitual do interior de PE / Implementation of the obstetric practices preferred by the humanization program in prenatal and birth in a maternity of habitual risk of the interior of PE

Objetivo: avaliar as práticas obstétricas vivenciadas pelas puérperas durante a assistência ao processo de parto e nascimento. Método: estudo de corte transversal, de natureza descritiva, com abordagem quantitativa, utilizando variáveis referentes as práticas obstétricas preconizadas pelo Programa de Humanização do Pré-Natal e Nascimento (PHPN), realizadas durante a assistência ao parto. Tendo como amostra puérperas que passaram por parto normal em uma maternidade do interior de PE e que estiveram no Alojamento Conjunto durante o período puerperal. A coleta dos dados ocorreu através de um questionário individual, semiestruturado, autoaplicável e anônimo no período de maio de 2017. Os dados foram analisados pelo programa estatístico epi-info versão 3.5.2. O estudo foi aprovado pela Plataforma Brasil sob nº 1.912.320/2017. Resultados: foram analisados 60 questionários, onde se obteve resultados sobre as práticas obstétricas adotadas no ciclo gravídico puerperal. Conclusão: entendesse que, para diminuir a morbimortalidade é necessário humanizar o processo de parturição, e para isto ocorrer é necessário o envolvimento de um conjunto de profissionais de saúde que prestam assistência à mulher durante o ciclo gravídico-puerperal

Feno de maniçoba na alimentação de caprinos Moxotó

The use of native forages Caatinga set up as an alternative for the sustainable production systems in Northeast Brazil. This study aimed to evaluate the substitution of Tifton 85 hay by Maniçoba hay in the components of the body weight of Moxotó goats. The animals were steers, initially weighing 21.67±3.92 kg, housed in individual pens and slaughtered at 58 days of confinement. The type of hay did not influence (P>0.05) any of the carcass traits. The animals presented for slaughter average body weight of 21.83 kg, and average weights of hot and cold carcass of 9.83 kg and 9.21 kg, respectively. The carcass were not affected by the type of hay (P>0.05) and average 44.98% and 42.11% for hot cold carcass. The loin eye area (LEA) and carcass compactness index had averages of 6.19 cm² and 0.159 kg cm-1, respectively, and did not influence the type of hay in the diet. There was no difference (P> 0.05) between diets for weight of organs and viscera. The diet Tifton 85 yielded higher (P0,05) nenhuma das características de carcaça dos caprinos. Os animais apresentaram peso corporal ao abate médio de 21,83 kg e pesos médios de carcaça quente e fria de 9,83 kg e 9,21 kg, respectivamente. Os rendimentos de carcaça também não foram influenciados pelo tipo de feno (P>0,05) e apresentaram médias de 44,98% para carcaça quente e 42,11% para carcaça fria. A área de olho de lombo (AOL) e o índice de compacidade da carcaça apresentaram médias de 6,19 cm² e 0,159 kg cm-1, respectivamente, e não sofreram influência do tipo de feno na dieta. Não foi observada diferença (P>0,05) entre as dietas para peso de órgãos e vísceras. A dieta Tifton 85 proporcionou maiores (P<0,05) pesos de pele. A substituição do feno de Tifton 85 pelo feno de Maniçoba, na dieta de caprinos Moxotó, não altera nenhum componente da carcaça, contudo em relação aos constituintes não carcaça, reduz o peso da pele.

Phytochemical bioprospecting, antioxidant, antimicrobial and cytotoxicity activities of saline extract from Tithonia diversifolia (Hemsl) A. Gray leaves

Objective: To evaluate antimicrobial and antioxidant properties of saline extract from Tithonia diversifolia leaves by phytochemical bioprospecting, and investigate its safety against animal cells. Methods: The saline extract was prepared, with NaCl (0.15 M), by constant stirring of the dried and pulverized leaves, followed by volume reduction by lyophilization. The extract was phytochemical characterized using ultra-performance liquid chromatography, and total phenol and flavonoid analysis also was performed. The antioxidant capacity was determined through DPPH· radical, the antimicrobial property was evaluated against standard bacteria and fungi, and the viability assays were performed against mice splenocytes. Results: Fifteen compounds were identified belonging to two main classes terpenoids and phenolics. The extract showed 22.185 mg GAE/g of total phenolic compounds and 3.220 mg QE/g of flavonoid. Moreover, extract showed higher antioxidant ability similar to butylated hydroxytoluene a standard molecule [(3.042±0.019) mg AAE/g and (4.12±0.10) mg AAE/g to saline extract and butylated hydroxytoluene, respectively]. The antimicrobial assays demonstrated that the extract had a significant antifungal potential against Candida species and could be used with safety against mice splenocytes, in concentrations lower than 50 μg/mL, promoting higher proliferation in these cells. Conclusions: Saline extract from Tithonia diversifolia leaves presents potential antioxidant, antifungal properties and induces immunostimulation in mice splenocytes

Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.

Abstract: Currently, the research of new natural compounds with biological potential demonstrates great ethnopharmacological importance. In this study, we evaluated the biological properties promoted by saline extract from Malpighia emarginata DC leaves, whose objective is to evaluate the antioxidant, antimicrobial and cytotoxicity potential. Phytochemical characterization was performed by UPLC-MS chromatography to identify the chemical compounds. For the antioxidant potential, DPPH, ATT and FRAP methods were used. The antibacterial and antifungal tests were performed evaluating the MIC50, MIC90, CMB and CMF parameters. Moreover, antibiofilm action was evaluated. Cytotoxicity and proliferation were performed using splenocytes from Balb/c mice and were evaluated by cytometry. We found a list of phenolic compounds among other bioactive compounds in the M. emarginata saline extract. In addition, higher antioxidant profile and antifungal activity against different strains of Candida spp. was promoted by the saline extract. Splenocytes showed greater cell viability (more than 90%) and showed higher proliferate index in 24 and 48 hours of incubation with the extract. Saline extract from Malpighia emarginata DC has potential action like antioxidant and antifungal agent without promote animal cell damage

Risk of adverse outcomes in offspring with RT-PCR confirmed prenatal Zika virus exposure: an individual participant data meta-analysis of 13 cohorts in the Zika Brazilian Cohorts ConsortiumResearch in context

Summary: Background: Knowledge regarding the risks associated with Zika virus (ZIKV) infections in pregnancy has relied on individual studies with relatively small sample sizes and variable risk estimates of adverse outcomes, or on surveillance or routinely collected data. Using data from the Zika Brazilian Cohorts Consortium, this study aims, to estimate the risk of adverse outcomes among offspring of women with RT-PCR-confirmed ZIKV infection during pregnancy and to explore heterogeneity between studies. Methods: We performed an individual participant data meta-analysis of the offspring of 1548 pregnant women from 13 studies, using one and two-stage meta-analyses to estimate the absolute risks. Findings: Of the 1548 ZIKV-exposed pregnancies, the risk of miscarriage was 0.9%, while the risk of stillbirth was 0.3%. Among the pregnancies with liveborn children, the risk of prematurity was 10,5%, the risk of low birth weight was 7.7, and the risk of small for gestational age (SGA) was 16.2%. For other abnormalities, the absolute risks were: 2.6% for microcephaly at birth or first evaluation, 4.0% for microcephaly at any time during follow-up, 7.9% for neuroimaging abnormalities, 18.7% for functional neurological abnormalities, 4.0% for ophthalmic abnormalities, 6.4% for auditory abnormalities, 0.6% for arthrogryposis, and 1.5% for dysphagia. This risk was similar in all sites studied and in different socioeconomic conditions, indicating that there are not likely to be other factors modifying this association. Interpretation: This study based on prospectively collected data generates the most robust evidence to date on the risks of congenital ZIKV infections over the early life course. Overall, approximately one-third of liveborn children with prenatal ZIKV exposure presented with at least one abnormality compatible with congenital infection, while the risk to present with at least two abnormalities in combination was less than 1.0%. Funding: National Council for Scientific and Technological Development - Brazil (Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq); Wellcome Trust and the United Kingdom's Department for International Development; European Union's Horizon 2020 research and innovation program; Medical Research Council on behalf of the Newton Fund and Wellcome Trust; National Institutes of Health/National Institute of Allergy and Infectious Diseases; Foundation Christophe et Rodolphe Mérieux; Coordination for the improvement of Higher Education Personnel (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Capes); Ministry of Health of Brazil; Brazilian Department of Science and Technology; Foundation of Research Support of the State of São Paulo (Fundação de Amparo à Pesquisa do Estado de São Paulo – FAPESP); Foundation of Research Support of the State of Rio de Janeiro (Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro – FAPERJ); Foundation of Support for Research and Scientific and Technological Development of Maranhão; Evandro Chagas Institute/Brazilian Ministry of Health (Instituto Evandro Chagas/Ministério da Saúde); Foundation of Research Support of the State of Goiás (Fundação de Amparo à Pesquisa do Estado de Goiás – FAPEG); Foundation of Research Support of the State of Rio Grande do Sul (Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul – FAPERGS); Foundation to Support Teaching, Research and Assistance at Hospital das Clínicas, Faculty of Medicine of Ribeirão Preto (Fundação de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto); São Paulo State Department of Health (Secretaria de Saúde do Estado de São Paulo); Support Foundation of Pernambuco Science and Technology (Fundação de Amparo à Ciência e Tecnologia de Pernambuco – FACEPE)

Uma história de conceitos na saúde pública: integralidade, coordenação, descentralização, regionalização e universalidade A history of public health concepts: integrity, coordination, decentralization, regionalization, and universality

O Sistema Único de Saúde conferiu visibilidade a uma série de conceitos próprios da organização de sistemas de saúde. Entre eles a integralidade, que delimita fronteiras comuns com quase todos os demais princípios do Sistema, tem sido objeto de ampla literatura no Brasil. Com base em extensa revisão de fontes primárias e secundárias, este artigo apresenta uma recuperação histórica dos conceitos de integralidade, descentralização, regionalização e universalidade - ideias e conceitos que em grande parte se conformam e se interligam no ideário da organização dos serviços sanitários pelo modelo dos Centros de Saúde distritais.<br>Brazil's Unified Health System (Sistema Único de Saúde) has highlighted a series of concepts specific to the organization of healthcare systems. Among these, integrity - which shares boundaries with almost all other System principles - has been the object of much academic production in Brazil. Based on an extensive review of primary and secondary sources, the article offers a historical recovery of the concepts of integrity, decentralization, regionalization, and universality - ideas and concepts that in good measure are shaped by and interlinked with the set of ideals of the organization of sanitary services according to the district health centers model