Clustering the technical capability in the brazilian aeronautical maintenance industry

In the sectors where equipment requiring services of maintenance are technologically complex and advanced, such as in the air transportation, knowing and managing the technical capability of the enterprises of the sector can be a good way maximizing the efforts of training. This paper attempts to present a process of technical capability clustering for the aeronautical maintenance industry, in order to provide a usable overview of the sector competences. The findings present a unique insight into the understanding of competences clustering that may be used across different industries

Polimorfismos genéticos dos genes CTLA4, NOS3 e CYP em pacientes diagnosticados com Acidente Vascular Encefálico Hemorrágico (AVEH) e/ou aneurisma intracerebral em uma amostra do Distrito Federal

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Patologia Molecular, 2017.O Acidente Vascular Encefálico (AVE) corresponde a uma disfunção neurológica aguda causada pela interrupção do fluxo sanguíneo em áreas do encéfalo, ocasionando diversas incapacidades e o acometimento global interfere em atividades diárias da vida do paciente. O Acidente Vascular Encefálico Hemorrágico (AVEH), compreende a hemorragia subaracnóide e a hemorragia intraparenquimatosa, que tem como principal doença associada a hipertensão arterial sistêmica (HAS). No Brasil, são registradas mais de 68 mil mortes por AVE anualmente, tal doença representa a primeira causa de morte e incapacidade no país, gerando impacto social e econômico. Neste trabalho foram avaliados Polimorfismos Genéticos em pacientes diagnosticados com AVEH e/ou Aneurisma Intracerebral. Polimorfismo genético pode ser compreendido quando há mutação de nucleotídeos em pelo menos 1% dos indivíduos da espécie, onde um específico gene apresenta variações em suas sequências codificadora, não-codificadora ou promotoras, o que pode acarretar fenótipos diferentes. O objetivo do presente estudo foi investigar possível associação entre os polimorfismos dos genes CTLA4, NOS3 e CYP e a ocorrência do AVEH e/ou Aneurisma Intracerebral, descrevendo frequências alélicas e genotípicas, avaliando diferentes manifestações clínicas e prognósticos de pacientes residentes no Distrito Federal. Os participantes preencheram uma ficha de identificação e foram sujeitos à coleta de sangue venoso. Após a coleta, foi realizada extração do DNA, PCR-RFLP e análise do genótipo. As frequências genotípicas foram estimadas por contagem direta, por meio do programa SPSS versão 23.0. Para comparação das distribuições das frequências foi aplicado o teste do qui-quadrado, de forma a detectar possíveis associações dos genótipos entre os grupos caso e controle. Foram consideradas associações com probabilidades menores que 5% (P<0,05). Concluiu-se que independente do polimorfismo a presença da HAS é um fator de risco para a ocorrência de AVEH/Aneurisma e quando analisado o polimorfismo CTLA4 -318 C/T, a presença do genótipo CT, foi considerada um fator de risco para a ocorrência de AVEH/Aneurisma. Os demais polimorfismos não obtiveram diferença estatística quanto à associação entre os diferentes genótipos.Stroke refers to an acute neurological dysfunction caused by disruption of blood flow in areas of the brain, causing various disabilities, and global impairment interferes with daily activities of the patient's life. Hemorrhagic Stroke (HS), includes subarachnoid hemorrhage and intraparenchymal hemorrhage, which has as its main disease associated with systemic arterial hypertension (SAH). In Brazil, more than 68 thousand deaths per year are registered, this disease represents the first cause of death and disability in the country, generating social and economic impact. Genetic polymorphism can be understood when there is a mutation of nucleotides in at least 1% of the individuals of the species, where a specific gene presents variations in its coding, non-coding or promoter sequences, which can lead to different phenotypes. The aim of the present study was to investigate possible association between the CTLA4, NOS3 and CYP gene polymorphisms and the occurrence of hemorrhagic stroke/intracerebral aneurysm, describing allelic and genotype frequencies, evaluating different clinical manifestations and prognoses of patients residing in the Federal District. Participants filled out an identification form and were subjected to venous blood collection. After the collection, DNA extraction, PCR-RFLP and genotype analysis were performed. The genotypic frequencies were estimated by direct counting, using SPSS software version 23.0. To compare the frequency distributions, the chi-square test was applied in order to detect possible associations of genotypes between the case and control groups. Associations with probabilities less than 5% (P <0.05) were considered. It was concluded that regardless of the polymorphism the presence of SAH is a risk factor for the occurrence of hemorrhagic stroke/Aneurysm. Analyzing the CTLA4 -318 C/T polymorphism, the presence of the CT genotype was considered a risk factor for the occurrence of hemorrhagic stroke/Aneurysm. The other polymorphisms did not present statistical difference regarding the association between the different genotypes

Fatores da cultura Kaingang que interferem no cuidado ao idoso: olhar dos profissionais de saúde

OBJECTIVE: to describe the health professionals' perception in relation to the factors of the Kaingang culture which influence the undertaking of healthcare practices with the elders in this ethnic group. METHOD: descriptive research with a qualitative approach, grounded in the ethnographic method, undertaken with ten health professionals who work in the Indigenous Territory in Faxinal, in the Brazilian state of Paraná. The data was collected in the period November 2010 to February 2012 through interviews and participant observation, and was analyzed in the light of the Transcultural Nursing Theory. RESULTS: evidence was found that the Kaingang culture has a strong influence on the professional care for the older adult, principally due to the cultural strangeness of certain customs, aspects which limit the health care for such older adults being listed. CONCLUSION: knowledge of the influences on the care can contribute to the forming of a framework of information relevant to the professional in the provision of care for the Kaingang older adults.OBJETIVO: describir la percepción de los profesionales de la salud en cuanto a los factores de la cultura Kaingang que interfieren en la realización de las prácticas de cuidado a los ancianos de esa etnia. MÉTODO: investigación descriptiva, de abordaje cualitativo, fundamentada en el método etnográfico, realizada en diez profesionales de la salud que actúan en la Tierra Indígena Faxinal, estado de Paraná, Brasil. Los datos fueron recolectados en el período de noviembre de 2010 a febrero de 2012 por medio de entrevistas y observación participante, siendo analizados bajo la Teoría Transcultural del Cuidado. RESULTADOS: se evidenció gran interferencia de la cultura Kaingang en el cuidado profesional al anciano, principalmente en el extrañeza cultural de diversas costumbres listadas como aspectos limitadores para asistencia a la salud de esos ancianos. CONCLUSIÓN: el conocimiento de las interferencias de la asistencia puede contribuir en la formación de una plataforma de informaciones relevantes a los profesionales de salud en la ejecución del cuidado a los ancianos Kaingang.OBJETIVO: descrever a percepção dos profissionais de saúde quanto aos fatores da cultura Kaingang que interferem na realização das práticas de cuidado aos idosos dessa etnia. MÉTODO: pesquisa descritiva, de abordagem qualitativa, fundamentada no método etnográfico, realizada junto a dez profissionais de saúde que atuam na Terra Indígena Faxinal, Paraná, Brasil. Os dados foram coletados no período de novembro de 2010 a fevereiro de 2012, por meio de entrevistas e observação participante, sendo analisados à luz da Teoria Transcultural do Cuidado. RESULTADOS: evidenciou-se grande interferência da cultura Kaingang no cuidado profissional ao idoso, principalmente no estranhamento cultural de diversos costumes, elencando como aspectos limitadores para assistência em saúde de tais idosos. CONCLUSÃO: o conhecimento das interferências da assistência pode contribuir para a formação de um arcabouço de informações relevantes aos profissionais de saúde na execução do cuidado aos idosos Kaingang

Nodule-specific modulation of glutamine synthetase in transgenic medicago truncatula leads to inverse alterations in asparagine synthetase expression

Transgenic Medicago truncatula plants were produced harboring chimeric gene constructs of the glutamine synthetase (GS) cDNA clones (MtGS1a or MtGS1b) fused in sense or antisense orientation to the nodule-specific leghemoglobin promoter Mtlb1. A series of transgenic plants were obtained showing a 2- to 4-fold alteration in nodule GS activity when compared with control plants. Western and northern analyses revealed that the increased or decreased levels of GS activity correlate with the amount of cytosolic GS polypeptides and transcripts present in the nodule extracts. An analysis of the isoenzyme composition showed that the increased or decreased levels of GS activity were attributable to major changes in the homo-octameric isoenzyme GS1a. Nodules of plants transformed with antisense GS constructs showed an increase in the levels of both asparagine synthetase (AS) polypeptides and transcripts when compared with untransformed control plants, whereas the sense GS transformants showed decreased AS transcript levels but polypeptide levels similar to control plants. The polypeptide abundance of other nitrogen metabolic enzymes NADH-glutamic acid synthase and aspartic acid aminotransferase as well as those of major carbon metabolic enzymes phosphoenolpyruvate carboxylase, carbonic anhydrase, and sucrose synthase were not affected by the GS-gene manipulations. Increased levels of AS polypeptides and transcripts were also transiently observed in nodules by inhibiting GS activity with phosphinothricin. Taken together, the results presented here suggest that GS activity negatively regulates the level of AS in root nodules of M. truncatula. The potential role of AS in assimilating ammonium when GS becomes limiting is discussed.info:eu-repo/semantics/publishedVersio

Satisfacción con el tratamiento y calidad de vida en adolescentes con DMT1 mediante infusión continua de insulina subcutánea

Introdução: O sistema de perfusão subcutânea contínua de insulina (PSCI) tem sido priorizado no controlo metabólico de crianças e jovens com Diabetes Mellitus tipo 1 (DM1). Objetivo: Avaliar a qualidade de vida e a satisfação com o tratamento em adolescentes com DM1 que utilizam o sistema PSCI; Analisar o papel da qualidade de vida na predição da sua satisfação com o tratamento. Métodos: Participaram 77 adolescentes, entre os 10 e os 18 anos. Utilizaram se dois questionários, um sobre Qualidade de vida associada ao tratamento com PSCI e outro sobre Satisfação com este tipo de tratamento. Resultados: Os adolescentes tendem, maioritariamente a manifestar uma boa qualidade de vida, com valores mais baixos nas dimensões relativas ao Impacto da Diabetes, Sentimentos e Humor e Tempos Livres. Estão ainda satisfeitos com o sistema PSCI.. Através da regressão linear múltipla, testou-se um modelo de predição, tendo o Impacto da diabetes, os Tempos livres e os Sentimentos e humor explicado 32,7% da variância da Satisfação com o tratamento com PSCI. Conclusão: O uso da PSCI é uma resposta terapêutica que os adolescentes com DM1 percebem como promotora da sua qualidade de vida e globalmente satisfatória, o que vai ao encontro da evidência. Porém, na promoção da adaptação à doença e regime terapêutico, aspetos como as implicações na autoimagem e a gestão emocional devem ser domínios de especial atenção.Introduction: Continuous subcutaneous insulin infusion (CSII) has been prioritised in the metabolic control of type 1 Diabetes Mellitus (T1DM) in children and adolescents. Objective: To assess the quality of life and treatment satisfaction in adolescents with T1DM using CSII and analyse the role of quality of life in predicting treatment satisfaction among these adolescents. Methods: The sample comprised 77 adolescents aged 10 to 18, followed-up in two central hospitals in the Northern region of Portugal. The Quality-of-Life questionnaire for treatment with Insulin Infusion Pump – adolescents’ version - and the adapted version for adolescents of treatment satisfaction with Insulin Pump questionnaire were used. Results: Most adolescents reported a good quality of life, with lower values in the dimensions related to the Impact of Diabetes, Feelings and Mood and Leisure. They were satisfied with the CSII system, recognizing it as convenient, easy to use and guarantying autonomy. A prediction model was tested through multiple linear regression, with the Impact of diabetes, Leisure Time and Feelings and mood explaining 32.7% of the variance of treatment satisfaction. Conclusion: CSII is a therapeutic option that adolescents with T1DM perceive to promote their quality of life and consider satisfactory, in line with the previous evidence. However, interventions aimed to support these adolescents in managing their disease and treatment should focus on aspects such as self-image and emotional well-being.Introducción: La infusión continua de insulina subcutánea (IICS) ha sido priorizada en el control metabólico de la Diabetes Mellitus tipo 1 (DM1) en niños y adolescentes. Objetivo: Evaluar la calidad de vida y la satisfacción con el tratamiento en adolescentes con DM1 utilizando IICS, y analizar el papel de la calidad de vida en la predicción de la satisfacción con el tratamiento en estos adolescentes. Métodos: Participaram 77 adolescentes, de 10 a 18 años, Se utilizó el cuestionario de Calidad de Vida para el tratamiento con IICS y el cuestionario de satisfacción del tratamiento con IICS. Resultados: La mayoría de los adolescentes reportaron una buena calidad de vida, con valores más bajos en las dimensiones relacionadas con el Impacto de la Diabetes, sentimientos y Estado de Ánimo y Ocio. Están satisfechos con el sistema IICS. A través de la regresión lineal múltiple, se probó un modelo de predicción, con el Impacto de la diabetes, el Tiempo de Ocio y los Sentimientos y el estado de ánimo explicando el 32,7% de la varianza de la satisfacción con el tratamiento. Conclusión: La IICS es una opción terapéutica que los adolescentes con DM1 perciben como promotora de su calidad de vida y se sienten como satisfactoria, en línea con la evidencia previa. Sin embargo, las intervenciones dirigidas a apoyar a estos adolescentes para manejar su enfermedad y tratamiento deben centrarse en aspectos como la autoimagen y el bienestar emocional.info:eu-repo/semantics/publishedVersio

Uso de um website como uma abordagem diferenciada no ensino da química

Anais do II Seminário Seminário Estadual PIBID do Paraná: tecendo saberes / organizado por Dulcyene Maria Ribeiro e Catarina Costa Fernandes — Foz do Iguaçu: Unioeste; Unila, 2014Com o advento da informática e a proliferação do uso da internet para grande parte da população houve uma grande melhoria no processo de aprendizagem, havendo inúmeras possibilidades de metodologias alternativas para que servissem não somente como apoio para o professor, mas como extensão do processo educacional. Este trabalho teve como objetivo à utilização de um website como ferramenta auxiliar e alternativa no ensino de Química para os alunos de Ensino Médio do Colégio Estadual Santa Cândida em Curitiba-PR. Posteriormente foi realizada uma atividade para os alunos entrarem em contato com o site e obtiveram-se resultados positivos tanto na avaliação da estética do site, assim como ferramenta educaciona

Impact of fetal mortality on prematurity in Argentina: A population based study

Background: It has been observed that the increase in preterm births was accompanied by a decrease in fetal mortality.Objective: To evaluate the relationship between fetal mortality and prematurity in Argentina.Methods: Ecological design. The population included all live births and fetal demise in Argentina between 2003 and 2013. Outcomes: total fetal mortality rate (TFMR), fetal mortality rate by birth weight, fetal mortality rate, neonatal mortality rate, perinatal mortality rate, trends in fetal mortality rates specific for gestational age (GA), and prematurity (&lt;37+ 0 weeks). Independent variables: age (&lt;19 and &gt; 35 years), education &lt;8 years, with partner, parity 1 and &gt; 4, multiple pregnancy and birth rate. Statistical analysis: linear regression analysis adjusted for covariates.Results: TFMR showed an annual reduction of 0.18 per thousand births that decreased with the increase of GA, being the largest reduction below 28+0 weeks (68%), while prematurity increased 0.07% per year, being the largest increase (0.75%) between 32+0 and 36+6 weeks. Linear regression model showed an inverse relationship between TFMR and prematurity (adjusted R2 0.76, p = 0.010), being the highest between 32+0 and 36+6 weeks (adjusted R2 = 0.98, p &lt; 0.001).Conclusions: The reduction in fetal mortality was associated with the observed increase in preterm births in Argentina.</p

Crown size and transplant type on the strawberry yield

Strawberry (Fragaria x ananassa D.) yield is affected by vigor of transplants. Those young and vigorous at planting lead to plants reaching higher vegetative growth and fruit yield than weak or old ones. This study aimed at determining plant growth, development, and fruit yield of the strawberry plant from bare root and plug transplants with different crown diameters. Bare root transplants were produced by rooting stolons and plug transplants from runner tips collected and rooted in a substrate growing bed. Three classes of crown diameters were compared in a 2 × 3 factorial and randomized block experimental design, with four replications, 16 plants per plot and a density of 6.6 plants m-2. For bare root transplants, crown diameters were between 3.0 and 5.0 mm (class 1); 5.1 and 8.0 mm (class 2) and greater than 8.1 mm (class 3). For plug transplants, runner tips were screened between 2.0 and 3.9 mm (class 1); 4.0 and 5.5 mm (class 2) and 5.6 to 7.0 mm (class 3). Transplants of both types were planted at April 16th, 2008, and at this date, crown diameter, shoot and root dry mass and number of leaves were higher in all classes of plug transplants. Ripe fruits were harvested from June 15th to November 7th, 2008, and fresh fruit yield was determined. Plant growth and development were determined at last harvest. Higher growth, development and fruit yield were obtained in plants from plug transplants. For bare root transplants, crown diameters higher than 5.1 mm can be used while for plug transplants the crown diameter of runner tips does not affect plant growth and fruit yield

Cluster of aeronautical maintenance companies in Brazil

[ENG] Brazilian domestic market for air transportation is the largest in Latin American and it has grown at a rate of 10% between 2003 and 2008 reaching over 50 million trips per year . According to the McKinsey study, it is likely that this sector continues to grow at very relevant rates, given the expectation of income growth and therefore the demand for air transportation for poorer regions and classes in Brazil. This air transportation growth requires an aircraft maintenance industry capable to support such an expansive process, without any prejudice to flight safety and continued airworthiness. Therefore, it is expected that Brazilian maintenance sector receives strong investments for years to come, generating important returns for the economy of Brazil. Under this scenario, it can be expected that the expansion of maintenance sector will contribute to Brazil's economic development through: increasing the participation of small and medium companies, due to the existence of small capital and technological barriers; the expansion of technical and technological job opportunities; the geographical spread of capabilities in maintenance services, with the entry of these activities into regions with lower levels of air traffic; encouragement to develop a local industry of aircraft spare parts.Thus, in order to support the decision making of investors and the development of public policies, it is necessary to build an overview of current conditions of the Brazilian aviation maintenance industry.This work was supported by CAPES