Functional adaptivity for digital library services in e-infrastructures: the gCube approach

We consider the problem of e-Infrastructures that wish to reconcile the generality of their services with the bespoke requirements of diverse user communities. We motivate the requirement of functional adaptivity in the context of gCube, a service-based system that integrates Grid and Digital Library technologies to deploy, operate, and monitor Virtual Research Environments defined over infrastructural resources. We argue that adaptivity requires mapping service interfaces onto multiple implementations, truly alternative interpretations of the same functionality. We then analyse two design solutions in which the alternative implementations are, respectively, full-fledged services and local components of a single service. We associate the latter with lower development costs and increased binding flexibility, and outline a strategy to deploy them dynamically as the payload of service plugins. The result is an infrastructure in which services exhibit multiple behaviours, know how to select the most appropriate behaviour, and can seamlessly learn new behaviours

The Wigner function of a q-deformed harmonic oscillator model

The phase space representation for a q-deformed model of the quantum harmonic oscillator is constructed. We have found explicit expressions for both the Wigner and Husimi distribution functions for the stationary states of the $q$-oscillator model under consideration. The Wigner function is expressed as a basic hypergeometric series, related to the Al-Salam-Chihara polynomials. It is shown that, in the limit case $h \to 0$ ($q \to 1$), both the Wigner and Husimi distribution functions reduce correctly to their well-known non-relativistic analogues. Surprisingly, examination of both distribution functions in the q-deformed model shows that, when $q \ll 1$, their behaviour in the phase space is similar to the ground state of the ordinary quantum oscillator, but with a displacement towards negative values of the momentum. We have also computed the mean values of the position and momentum using the Wigner function. Unlike the ordinary case, the mean value of the momentum is not zero and it depends on $q$ and $n$. The ground-state like behaviour of the distribution functions for excited states in the q-deformed model opens quite new perspectives for further experimental measurements of quantum systems in the phase space.Comment: 16 pages, 24 EPS figures, uses IOP style LaTeX, some misprints are correctd and journal-reference is adde

Actions speak louder than words: outsiders' perceptions of diversity mixed messages

To attract a gender diverse workforce, many employers use diversity statements to publicly signal that they value gender diversity. However, this often represents a misalignment between words and actions (i.e., a diversity mixed message) because most organizations are male dominated, especially in board positions. We conducted 3 studies to investigate the potentially indirect effect of such diversity mixed messages through perceived behavioral integrity on employer attractiveness. In Study 1, following a 2 x 2 design, participants (N = 225) were either shown a pro gender diversity statement or a neutral statement, in combination with a gender diverse board (4 men and 4 women) or a uniform all-male board (8 men). Participants' perceived behavioral integrity of the organization was assessed. In Study 2, participants (N = 251) either read positive or negative reviews of the organization's behavioral integrity. Employer attractiveness was then assessed. Study 3 (N = 427) investigated the impact of board gender composition on perceived behavioral integrity and employer attractiveness using a bootstrapping procedure. Both the causal-chain design of Study 1 and 2, as well as the significance test of the proposed indirect relationship in Study 3, revealed that a diversity mixed message negatively affected an organization's perceived behavioral integrity, and low behavioral integrity in turn negatively impacted employer attractiveness. In Study 3, there was also evidence for a tipping point (more than 1 woman on the board was needed) with regard to participants' perceptions of the organization's behavioral integrity

Harmonic oscillators coupled by springs: discrete solutions as a Wigner Quantum System

We consider a quantum system consisting of a one-dimensional chain of M identical harmonic oscillators with natural frequency $\omega$, coupled by means of springs. Such systems have been studied before, and appear in various models. In this paper, we approach the system as a Wigner Quantum System, not imposing the canonical commutation relations, but using instead weaker relations following from the compatibility of Hamilton's equations and the Heisenberg equations. In such a setting, the quantum system allows solutions in a finite-dimensional Hilbert space, with a discrete spectrum for all physical operators. We show that a class of solutions can be obtained using generators of the Lie superalgebra gl(1|M). Then we study the properties and spectra of the physical operators in a class of unitary representations of gl(1|M). These properties are both interesting and intriguing. In particular, we can give a complete analysis of the eigenvalues of the Hamiltonian and of the position and momentum operators (including multiplicities). We also study probability distributions of position operators when the quantum system is in a stationary state, and the effect of the position of one oscillator on the positions of the remaining oscillators in the chain

The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) from the endoplasmic reticulum

The K650E substitution in the fibroblast growth factor receptor 3 (FGFR3) causes constitutive tyrosine kinase activity of the receptor and is associated to the lethal skeletal disorder, thanatophoric dysplasia type II (TDII). The underlying mechanisms of how the activated FGFR3 causes TDII remains to be elucidated. FGFR3 is a transmembrane glycoprotein, which is synthesized through three isoforms, with various degrees of N-glycosylation. We have studied whether immature FGFR3 isoforms mediate the abnormal signaling in TDII. We show that synthesis of TDII-FGFR3 presents two phosphorylated forms: the immature non-glycosylated 98-kDa peptides and the intermediate 120-kDa glycomers. The mature, fully glycosylated 130-kDa forms, detected in wild type FGFR3, are not present in TDII. Endoglycosidase H cleaves the sugars on TDII intermediates thus indicating their intracellular localization in the endoplasmic reticulum. Accordingly, TDII-FGFR3-GFP co-localizes with calreticulin in the endoplasmic reticulum. Furthermore, following TDII transfection, signal transducer and activator of transcription 1 (STAT1) is phosphorylated in the absence of FGFR3 ligand and brefeldin A does not inhibit its activation. On the contrary, the cell membrane-anchored FRS2alpha protein is not activated in TDII cells. The opposite situation is observed in stable TDII cell clones where, despite the presence of phosphorylated mature receptor, STAT1 is not activated whereas FRS2alpha is phosphorylated. We speculate that the selection process favors cells defective in STAT1 activation through the 120-kDa TDII-FGFR3, thus allowing growth of the TDII cell clones. Accordingly, apoptosis is observed following TDII-FGFR3 transfection. These observations highlight the importance of the immature TDII-FGFR3 proteins as mediators of an abnormal signaling in TDII

Precision Measurement of 11Li moments: Influence of Halo Neutrons on the 9Li Core

The electric quadrupole moment and the magnetic moment of the 11Li halo nucleus have been measured with more than an order of magnitude higher precision than before, |Q| = 33.3(5)mb and mu=3.6712(3)mu_N, revealing a 8.8(1.5)% increase of the quadrupole moment relative to that of 9Li. This result is compared to various models that aim at describing the halo properties. In the shell model an increased quadrupole moment points to a significant occupation of the 1d orbits, whereas in a simple halo picture this can be explained by relating the quadrupole moments of the proton distribution to the charge radii. Advanced models so far fail to reproduce simultaneously the trends observed in the radii and quadrupole moments of the lithium isotopes.Comment: 4 pages, 4 figures, 1 tabl

Задачи глобальной экологии

Changes in the size distribution and composition of bimetallic Pd-Au nanoclusters have been observed after hydrogen exposure. This effect is caused by hydrogen-induced Ostwald ripening whereby the hydrogen reduces the binding energy of the cluster atoms leading to their detachment from the cluster. The composition changes due to a difference in mobility of the detached palladium and gold atoms on the surface. Fast palladium atoms contribute to the formation of larger nanoclusters, while the slower gold atoms are confined to the smaller nanoclusters. These transformations in the Pd-Au nanocluster size and composition set a limit for chemical reactions in which such nanoclusters are involved together with hydrogen

Politicizing air: On the political effects of spatial imagination

Air is invisible, though it has very real effects on our health and on the natural and built environment. Air is intangible, but that does not mean it is immaterial. Air’s components and pollutants are situated on the microscale, though effects can be observed on a macroscale. Air (and its pollution) are both natural and human-made. Air is hybrid, but its hybridity does not speak to us immediately. Air is untouchable though we are touched by it all the time. Air is often forgotten in social or academic discourse (Buzzelli 2008; Heynen 2013), though we cannot live for longer than...transcript Verla