1,296 research outputs found
La Universidad para el cambio: el caso de <i> “El cine, la escuela y los barrios”</i>
La UNLP se consolida como proyecto sociopolítico promoviendo el trabajo con los sectores más vulnerables de la sociedad. El caso del proyecto de extensión ejecutado por la Facultad de Periodismo y Comunicación Social de la UNLP, brinda a las escuelas secundarias de distintos barrios, el espacio para un debate acerca de las problemáticas que afrontan cotidianamente. Asimismo, profesionales y estudiantes universitarios aportan las herramientas básicas para que los jóvenes puedan difundir sus opiniones acerca de sus propias realidades, y así promover nuevas posibilidades de transformación y desarrollo, con las bases del trabajo conjunto y participativo
Don’t drone?:negotiating ethics of RPAS in emergency response
This paper explores discourses of automation as a key ethical concern in the development of Remotely Piloted Aircraft Systems for disaster response. We discuss problems arising from ‘humanistic’ dichotomies that pit human against machine, military against civil uses and experts against laypersons. We explore how it may be possible to overcome human-technology dichotomies
Ethically aware IT design for emergency response:from co-design to ELSI co-design
The latest EU funding framework, ‘Horizon 2020’, has moved consideration of ethical and societal implications of technology development to the fore. Yet, there is little guidance on how to do such research in practice, let alone how to innovate in ethically and socially sound ways. This paper addresses these issues in the context of a large scale EU funded project developing system of system innovations in IT supported emergency response. Building on collaborative design and a range of other approaches, the paper argues that just like ‘usability’, ethics cannot be invented or decided by experts, but has to be the product of engagement with the technology by directly or indirectly implicated publics. Facilitating such publics is a central element of what we call ‘ELSI Co-Design’. The paper outlines the theoretical and methodological underpinnings of this approach
Continuing education programme "Pädagogik für Gesundheitsberufe" (Pedagogy for Health Professions). An example of adult education at the Carinthia University of Applied Sciences
Die Fachhochschule Kärnten bietet neben regulären Studiengängen in den letzten Jahren vermehrt auch berufsbegleitende Weiterbildungslehrgänge an. Als ein Beispiel (erwachsenen-)pädagogischer Bildungsarbeit wird im vorliegenden Beitrag der berufsbegleitende Weiterbildungslehrgang „Pädagogik für Gesundheitsberufe“ vorgestellt und es wird der Frage nachgegangen, welchen Stellenwert hochschulische Weiterbildungsangebote im Kontext der Erwachsenenbildung haben. (DIPF/Orig.)In addition to its regular full-time study programmes, the Carinthia University of Applied Sciences has started to offer more and more part-time continuing education programmes. This article presents an example of (adult) educational work in the part-time continuing education programme “Pädagogik für Gesundheitsberufe” (Pedagogy for Health Professions), asking what status university continuing education offerings have in the context of adult education. (DIPF/Orig.
overview and meta-analysis of neuroimaging studies on motor conversion disorder
Background Conversion Disorders (CD) are prevalent functional disorders.
Although the pathogenesis is still not completely understood, an interaction
of genetic, neurobiological, and psychosocial factors is quite likely. The aim
of this study is to provide a systematic overview on imaging studies on CDs
and investigate neuronal areas involved in Motor Conversion Disorders (MCD).
Methods A systematic literature search was conducted on CD. Subsequently a
meta-analysis of functional neuroimaging studies on MCD was implemented using
an Activation Likelihood Estimation (ALE). We calculated differences between
patients and healthy controls as well as between affected versus unaffected
sides in addition to an overall analysis in order to identify neuronal areas
related to MCD. Results Patients with MCD differ from healthy controls in the
amygdala, superior temporal lobe, retrosplenial area, primary motor cortex,
insula, red nucleus, thalamus, anterior as well as dorsolateral prefrontal and
frontal cortex. When comparing affected versus unaffected sides, temporal
cortex, dorsal anterior cingulate cortex, supramarginal gyrus, dorsal temporal
lobe, anterior insula, primary somatosensory cortex, superior frontal gyrus
and anterior prefrontal as well as frontal cortex show significant
differences. Conclusions Neuronal areas seem to be involved in the
pathogenesis, maintenance or as a result of MCD. Areas that are important for
motor-planning, motor-selection or autonomic response seem to be especially
relevant. Our results support the emotional unawareness theory but also
underline the need of more support by conduction imaging studies on both CD
and MCD
Where Is Waldo? Visual search behavior in "Wimmelpictures"
In order to explore an image, the human eye functions like a spotlight, scanning the content from one object to the next. This visual search behavior is implemented with the help of attention control. The following work surveys the visual search behavior in "Wimmelpictures", a special type of busy pictures. The research objective is to analyze different search strategies and to work out possible differences concerning age and gender. The university experiment is carried out by an eye tracker that records the fixations and saccades of the test persons. The results indicate three forms of search strategy: based on a pattern, based on feature selection, or a mixture of both. Our data shows the search for special features of the target is the most successful. Furthermore there are no differences concerning gender but some concerning age. All age groups need more time to locate the target with an increasing number of distractors in the image. The size of the target is also relevant as a larger target is found more quickly than the smaller one
Designing for ethical innovation:a case study on ELSI co-design in emergency
The ever more pervasive ‘informationalization’ of crisis management and response brings both unprecedented opportunities and challenges. Recent years have seen the emergence of attention to ethical, legal and social issues (ELSI) in the field of Information and Communication Technology. However, disclosing (and addressing) ELSI issues in design is still a challenge because they are inherently relational, arising from interactions between people, the material and design of the artifact, and the context. In this article, we discuss approaches for addressing such ‘deeper’ and ‘wider’ political implications, values and ethical, legal and social implications that arise between practices, people and technology. Based on a case study from the BRIDGE project, which has provided the opportunity for deep engagement with these issues through the concrete exploration and experimentation with technologically augmented practices of emergency response, we present insights from our interdisciplinary work aiming to make design and innovation projects ELSI-aware. Crucially, we have seen in our study a need for a shift from privacy by design towards designing for privacy, collaboration, trust, accessibility, ownership, transparency etc., acknowledging that these are emergent practices that we cannot control by design, but rather that we can help to design for—calling for approaches that allow to make ELSI issues explicit and addressable in design-time
Sorafenib prevents human retinal pigment epithelium cells from light-induced overexpression of VEGF, PDGF and PlGF
Background
Cumulative light exposure is significantly associated with progression of age-related macular degeneration (AMD). Inhibition of vascular endothelial growth factor is the main target of current antiangiogenic treatment strategies in AMD. However, other growth factors, such as platelet-derived growth factor (PDGF) and placenta growth factor (PlGF), have a substantial impact on development of AMD. Previous reports indicate that sorafenib, an oral multikinase inhibitor, might have beneficial effects on exudative AMD. This study investigates the effects of sorafenib on light-induced overexpression of growth factors in human retinal pigment epithelial (RPE) cells. Methods
Primary human RPE cells were exposed to white light and incubated with sorafenib. Viability, expression, and secretion of VEGF-A, PDGF-BB, and PlGF and their mRNA were determined by reverse transcription-polymerase chain reactions, immunohistochemistry and enzyme-linked immunosorbent assays.
Results
Light exposure decreased cell viability and increased expression and secretion of VEGF-A, PDGF-BB and PlGF. These light-induced effects were significantly reduced when cells were treated with sorafenib at a dose of 1 mu g/ml.
Conclusion
The results show that sorafenib has promising properties as a potential antiangiogenic treatment for AMD
Potential Benefits and Withdrawal Effects of Cranial Nerve Non-invasive Neuromodulation on Functional Mobility for Individuals with Traumatic Brain Injury
Objective: Document and describe benefits and withdrawal effects of the Cranial Nerve Non-Invasive Neuromodulation (CN-NINM) intervention.
Background: Neuromodulation techniques can be used for the treatment of many diagnoses and conditions. Many current neuromodulation techniques have or can have negative consequences such as high cost, risk of surgical complications or infections, effects not lasting without the drug or stimulation presence, and need for medical experts\u27 direct oversight. A new rehabilitation intervention called CN-NINM may eliminate these negative factors, making it a promising tool for clinicians and participants. CN-NINM combines targeted training activities with mild, portable, electrical stimulation of the tongue to facilitate learning. It was created after repeated clinical observations and functional improvements were noted in related research. However, a great deal is not known about the intervention mechanisms. To date, no negative consequences have been documented.
Methods: An A-B-A-B-A single case experimental design five week intensive protocol was implemented with one participant with a TBI. Seven measures were collected including the Timed Up and Go, Romberg, Sharpened Romberg, 4 components of the Dynamic Gait Index, 5 components of the Community Balance & Mobility Scale, Gait Efficacy Scale-modified, Community Integration Questionnaire, and Participation Objective, Participation Subjective.
Results: While several assessments suggested improved function over the study period, quantitative measures did not demonstrate statistically significant improvement across phases of the study. No quantitative decline in functional gait was evident during withdrawal phases. The participant reported improvements during intervention weeks, including reduced tone and pain, increased gait confidence, and increased activity tolerance.
Conclusion: CN-NINM warrants additional research. While this study demonstrated no statistically significant effects during either intervention or withdrawal phases, several qualitative observations suggest that the intervention can potentially provide fast results with little to no risk and comparatively small cost. Further research should involve multiple individuals with a number of repeated baseline and outcome measures sufficient to attain pre- and post- treatment stability
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