2,438 research outputs found
Entitled to a sustainable career? Motherhood in science, engineering and technology
Sustaining careers and motherhood is particularly challenging in highly masculinised science, engineering and technology (SET) sectors. We explore this issue using a social comparison theory perspective, drawing on interviews with professional engineers and scientists from four companies, located in Italy, France and the Netherlands. We examine how decisions to reduce working hours are influenced by perceived ideological, normative and policy contexts. Despite contextual differences in opportunities and perceived entitlements and supports for family-friendly working hours, we found that sense of entitlement to do so without forfeiting career progression is limited across all the contexts. This attests to the enduring power of gendered organizational assumptions about ideal SET careers. Nevertheless we present examples of three women who achieved senior roles despite working reduced hours and discuss combinations of conditions which may facilitate sustainable careers and caring roles
Utilization of local materials as aids in teaching American history in the schools of Chelsea
Thesis (M.A.)--Boston University, 1949. This item was digitized by the Internet Archive
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Emergence of stimulus bound drinking with a reinforcement contingency,
Thesis (M.S.
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A cross-cultural study of identity : toward a definition of Africanity.
PsychologyDoctor of Philosophy (Ph.D.
The effect of antimony on the assay of gold and silver ores
Our problem was to determine the effect of antimony in assaying for gold and silver. The method of attack was to find loss of gold and silver: 1) with variable antimony and a constant temperature. 2) with variable temperature and constant antimony --page 1
Lifetime of OH masers at the tip of the asymptotic giant branch
Context: A large fraction of otherwise similar asymptotic giant branch stars
(AGB) do not show OH maser emission. As shown recently, a restricted lifetime
may give a natural explanation as to why only part of any sample emits maser
emission at a given epoch.
Aims: We wish to probe the lifetime of 1612 MHz OH masers in circumstellar
shells of AGB stars.
Methods: We reobserved a sample of OH/IR stars discovered more than 28 years
ago to determine the number of stars that may have since lost their masers.
Results: We redetected all 114 OH masers. The minimum lifetime inferred is
2800 years (1 sigma). This maser lifetime applies to AGB stars with strong mass
loss leading to very red infrared colors. The velocities and mean flux density
levels have not changed since their discovery. As the minimum lifetime is of
the same order as the wind crossing time, strong variations in the mass-loss
process affecting the excitation conditions on timescales of ~3000 years or
less are unlikely.
Keywords: OH masers -- Stars: AGB and post-AGB -- circumstellar matterComment: 8 pages, 5 figures, accepted for publication in Astronomy &
Astrophysic
Pharmacokinetic analysis after implantation of everolimus-eluting self-expanding stents in the peripheral vasculature
Background: A novel self-expanding drug-eluting stent was designed to release everolimus 225 mu g/cm(2) to prevent restenosis following peripheral arterial intervention. The purpose of this study was to measure the pharmacokinetic profile of everolimus following stent implantation.
Methods: One hundred four patients with symptomatic peripheral arterial disease underwent implantation of everolimus-eluting stents in the femoropopliteal arteries. In a prespecified subset of 26 patients, blood samples for assay of everolimus content were collected prior to stent implantation, at 1, 4, and 8 hours postprocedure, prior to discharge, and at 1 month postproccdure.
Results: A total of 39 stents, ranging from 28 mm to 100 mm in length, were implanted in 26 patients, resulting in a total delivered everolimus dose range of 3.0 to 7.6 mg. Following the procedure, the maximum observed everolimus blood concentrations (C-max) varied from 1.83 +/- 0.05 ng/mL after implantation of a single 80-mm stent to 4.66 +/- 1.78 ng/mL after implantation of two 100-mm stents. The mean time to peak concentration (T-max) varied from 6.8 hours to 35 hours. The pharmacokinetics of everolimus were dose-proportional in that dose-normalized C-max and area under the curve values were constant over the studied dose range.
Conclusions: After implantation of everolimus-eluting self-expanding stents in the femoropopliteal arteries, systemic blood concentrations of everolimus are predictable and considerably lower than blood concentrations observed following safe oral administration of everolimus
Trends in genetics research--prospects for development
Some aspects of current research are viewed in an attempt to anticipate major trends in the next few years. The observations indicate that geneticists in general are becoming more problem - than organism-oriented and are making more extensive use of interdisciplinary techniques. The techniques and instrumentation available now seem sufficiently powerful to resolve extreme biological details if the geneticist possesses the ingenuity to pose the right questions. There seems to be a shift of concern from analysis to synthesis, and the next decade may be characterized by increased biological rather than molecular approaches, as a better understanding of the architecture of living systems is reached and new types of interactions within cells, tissues and organs are revealed. During this forthcoming period human cellular and subcellular genetics is expected to achieve great prominence.HERMAN W. LEWIS, National Science Foundation, Washington, D.C
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