What's New in Hair Loss

Made available in DSpace on 2019-09-12T16:53:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2019The treatment of hair loss is a challenge for all dermatologists. New medications are needed due to lack of efficacy of many treatments or their side-effect profile. This article discusses the most recent literature updates on the use of retinoids in frontal fibrosing alopecia, platelet-rich plasma in androgenetic alopecia, and JAK inhibitors in alopecia areata.[Nogueira Santos, Leopoldo Duailibe] Santa Casa Sao Paulo Sch Med, Rua Doutor Cesario Motta Jr 61, BR-01221020 Sao Paulo, SP, Brazil[Nogueira Santos, Leopoldo Duailibe; Shapiro, Jerry] Municipal Publ Servant Hosp Sao Paulo, Rua Castro Alves 60, BR-01532000 Sao Paulo, SP, Brazil[Nogueira Santos, Leopoldo Duailibe] Universidade de Taubaté (Unitau), Ave Granadeiro Guimaraes 270, BR-12020130 Taubate, SP, Brazil[Nogueira Santos, Leopoldo Duailibe] NYU, Sch Med, Ronald O Perelman Dept Dermatol, 530 First Ave,Suite 7R, New York, NY 10016 US

Dermoscopy examination of petechial lesions in a patient with Dermatitis Herpetiformis

An uncommon skin manifestation of Dermatitis Herpetiformis is palmar and plantar purpura. Dermoscopic examination is useful for any skin condition since it allows recognition of structures that are not discernible to the naked eye. A 22 year-old Caucasian man was admitted with excoriated lesions and pruritus. Petechial lesions could be seen on volar aspect of the digits on the hands and feet. Dermoscopy examination revealed erythematous and violaceous dots and erythematous and brown dots

Porokeratosis of Mibelli - literature review and a case report

Porokeratosis is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center and hyperkeratotic edges, and includes a heterogeneous group of disorders that are mostly inherited in an autosomal dominant form. This report describes a 5 year-old female patient, with porokeratosis of Mibelli confirmed histopathologically. The rarity of this disorder, its clinical exuberance and the destructive character of the lesions, as well as the facial and mucosal involvements, unusual in this form of porokeratosis, and also its onset in early childhood motivated this report

A novel automated approach to rapid and precise in vivo measurement of hair morphometrics using a smartphone

Background Although many hair disorders can be readily diagnosed based on their clinical appearance, their progression and response to treatment are often difficult to monitor, particularly in quantitative terms. We introduce an innovative technique utilizing a smartphone and computerized image analysis to expeditiously and automatically measure and compute hair density and diameter in patients in real-time. Methods A smartphone equipped with a dermatoscope lens wirelessly transmits trichoscopy images to a computer for image processing. A black-and-white binary mask image representing hair and skin is produced and the hairs are thinned into single-pixel-thick fiber skeletons. Further analysis based on these fibers allows morphometric characteristics such as hair shaft number and diameters to be computed rapidly. The hair-bearing scalps of fifty participants were imaged to assess the precision of our automated smartphone-based device in comparison to a specialized trichometry device for hair shaft density and diameter measurement. The precision and operation time of our technique relative to manual trichometry, which is commonly used by hair disorder specialists, is determined. Results An equivalence test, based on two one-sided t-tests, demonstrates statistical equivalence in hair density and diameter values between this automated technique and manual trichometry within a 20% margin. On average, this technique actively required 24 seconds of the clinician's time whereas manual trichometry necessitated 9.2 minutes. Conclusion Automated smartphone-based trichometry is a rapid, precise, and clinically feasible technique which can significantly facilitate the assessment and monitoring of hair loss. Its use could be easily integrated into clinical practice to improve standard trichoscopy.Dermatology and Skin Science, Department ofMedicine, Faculty ofReviewedResearcherFacult