Semi-Markov adjunction to the Computer-Aided Markov Evaluator (CAME)

The rule-based Computer-Aided Markov Evaluator (CAME) program was expanded in its ability to incorporate the effect of fault-handling processes into the construction of a reliability model. The fault-handling processes are modeled as semi-Markov events and CAME constructs and appropriate semi-Markov model. To solve the model, the program outputs it in a form which can be directly solved with the Semi-Markov Unreliability Range Evaluator (SURE) program. As a means of evaluating the alterations made to the CAME program, the program is used to model the reliability of portions of the Integrated Airframe/Propulsion Control System Architecture (IAPSA 2) reference configuration. The reliability predictions are compared with a previous analysis. The results bear out the feasibility of utilizing CAME to generate appropriate semi-Markov models to model fault-handling processes

COVID-19 Vaccination Prioritization Based on Cardiovascular Risk Factors and Number-Needed-to-Vaccinate to Prevent Death

The supply limitations of COVID-19 vaccines have led to the need to prioritize vaccine distribution. Obesity, diabetes and hypertension have been associated with an increased risk of severe COVID-19 infection. Approximately half as many individuals with a cardiovascular risk factor need to be vaccinated against COVID-19 to prevent related death as compared with individuals without a risk factor. Adults with body-mass index ≥30kg/m2, diabetes or hypertension should be of a similar priority for COVID-19 vaccination to adults 10 years older with a body-mass index 20 to <30kg/m2, no diabetes and no hypertension

A Lotus 1-2-3 macro system to analyze a cross of haploid individuals

The use of RFLPs to construct saturated genetic maps results in the generation of very large sets of data. The management of these data, and the calculations needed to test for linkage relationships, is greatly facilitated by the use of an electronic spreadsheet on a personal computer. Using the spreadsheet Lotus 1-2-3TM (Lotus Development Corp., Cambridge, MA), we have found that the raw data can very efficiently be entered, viewed, edited, sorted, searched, and printed. We have written a program, utilizing Lotus 1-2-3 macro subcommands, that analyzes segregation data from a cross of haploid individuals in several way

Exploiting the Synergy Between Gossiping and Structured Overlays

In this position paper we argue for exploiting the synergy between gossip-based algorithms and structured overlay networks (SON). These two strands of research have both aimed at building fault-tolerant, dynamic, self-managing, and large-scale distributed systems. Despite the common goals, the two areas have, however, been relatively isolated. We focus on three problem domains where there is an untapped potential of using gossiping combined with SONs. We argue for applying gossip-based membership for ring-based SONs---such as Chord and Bamboo---to make them handle partition mergers and loopy networks. We argue that small world SONs---such as Accordion and Mercury---are specifically well-suited for gossip-based membership management. The benefits would be better graph-theoretic properties. Finally, we argue that gossip-based algorithms could use the overlay constructed by SONs. For example, many unreliable broadcast algorithms for SONs could be augmented with anti-entropy protocols. Similarly, gossip-based aggregation could be used in SONs for network size estimation and load-balancing purposes

Composting paper and grass clippings with anaerobically treated palm oil mill effluent

Purpose The purpose of this study is to investigate the composting performance of anaerobically treated palm oil mill effluent (AnPOME) mixed with paper and grass clippings. Methods Composting was conducted using a laboratory scale system for 40 days. Several parameters were determined: temperature, mass reduction, pH, electrical conductivity, colour, zeta potential, phytotoxicity and final compost nutrients. Results The moisture content and compost mass were reduced by 24 and 18 %, respectively. Both final compost pH value and electrical conductivity were found to increase in value. Colour (measured as PtCo) was not suitable as a maturity indicator. The negative zeta potential values decreased from −12.25 to −21.80 mV. The phytotoxicity of the compost mixture was found to decrease in value during the process and the final nutrient value of the compost indicates its suitability as a soil conditioner. Conclusions From this study, we conclude that the addition of paper and grass clippings can be a potential substrate to be composted with anaerobically treated palm oil mill effluent (AnPOME). The final compost produced is suitable for soil conditioner

Information theoretic approach to single-particle and two-particle interference in multi-path interferometers

We propose entropic measures for the strength of single-particle and two-particle interference in interferometric experiments where each particle of a pair traverses a multi-path interferometer. Optimal single-particle interference excludes any two-particle interference, and vice versa. We report an inequality that states the compromises allowed by quantum mechanics in intermediate situations, and identify a class of two-particle states for which the upper bound is reached. Our approach is applicable to symmetric two-partite systems of any finite dimension.Comment: RevTex 4, 4 pages, 2 figure

Disruption of a Yeast ADE6 Gene Homolog in Ustilago maydis

A putative homolog of the Sacharromyces cereviseae ADE6 and Escherichia coli purL genes is identified near a multigenic complex, which contains two genes, sid1 and sid2, involved in a siderophore biosynthetic pathway inUstilago maydis. The putative ADE6 homolog was mutated by targeted gene disruption. The resulting mutant strains demonstrated a requirement for exogenous adenine, indicating that the U. maydis ade6 homolog is required for purine biosynthesis