The future of factories: Different trends

The technological advancements promote the rise of the fourth industrial revolution, where key terms are efficiency, innovation, and enterprises’ digitalization. Market globalization, product mass customization, and more complex products need to reflect on changing the actual design methods and developing business processes and methodologies that have to be data-driven, AI-assisted, smart, and service-oriented. Therefore, there is a great interest in experimenting with emerging technologies and evaluating how they impact the actual business processes. This paper reports a comparison among the major trends in the digitalization of a Factory of the Future, in conjunction with the two major strategic programs of Industry 4.0 and China 2025. We have focused on these two programs because we have had experience with them in the context of the FIRST H2020 project. European industrialists identify the radical change in the traditional manufacturing production process as the rise of Industry 4.0. Conversely, China mainland launched its strategic plan in China 2025 to promote smart manufacturing to digitalize traditional manufacturing processes. The main contribution of this review paper is to report about a study, conducted and part of the aforementioned FIRST project, which aimed to investigate major trends in applying for both programs in terms of technologies and their applications for the factory’s digitalization. In particular, our analysis consists of the comparison between Digital Factory, Virtual Factory, Smart Manufacturing, and Cloud Manufacturing. We analyzed their essential characteristics, the operational boundaries, the employed technologies, and the interoperability offered at each factory level for each paradigm. Based on this analysis, we report the building blocks in terms of essential technologies required to develop the next generation of a factory of the future, as well as some of the interoperability challenges at a different scale, for enabling inter-factories communications between heterogeneous entities

Multi-layer model for the web graph

This paper studies stochastic graph models of the WebGraph. We present a new model that describes the WebGraph as an ensemble of different regions generated by independent stochastic processes (in the spirit of a recent paper by Dill et al. [VLDB 2001]). Models such as the Copying Model [17] and Evolving Networks Model [3] are simulated and compared on several relevant measures such as degree and clique distribution

A Codazzi-like equation and the singular set for C1C^{1} smooth surfaces in the Heisenberg group

In this paper, we study the structure of the singular set for a $C^{1}$ smooth surface in the $3$-dimensional Heisenberg group $\boldsymbol{H}_{1}$. We discover a Codazzi-like equation for the $p$-area element along the characteristic curves on the surface. Information obtained from this ordinary differential equation helps us to analyze the local configuration of the singular set and the characteristic curves. In particular, we can estimate the size and obtain the regularity of the singular set. We understand the global structure of the singular set through a Hopf-type index theorem. We also justify that Codazzi-like equation by proving a fundamental theorem for local surfaces in $\boldsymbol{H}_{1}$.Comment: 64 pages, 17 figure

Predatory ability of generalist predators on eggs, young nymphs and adults of the invasive Halyomorpha halys in southern Europe

Halyomorpha halys (Stål, 1855) is an invasive pest causing serious damage to agricultural crops in Europe and the USA. Very little is known about H. halys predators in Europe. This survey evaluated the potential of generalist predators/omnivorous species by means of predation bioassays in tri-dimensional arenas, where the predator had to locate H. halys prey items on the leaves of a bean plant. Eleven species of different taxa were tested and the prey items consisted in fresh eggmasses, 1st and 2nd instar nymphs. One species was also tested against adults. Some predators were species commercially available as biocontrol agents against plant pests, other predators were wild, captured in habitats shared with H. halys. All tested specimens were starved 24 h before starting the experiment. The survivorship of control prey items in predator-excluding cages was compared to that of predator treatment groups to determine the effect of predator presence. According to the results, the generalist species showed a quite low acceptance of H. halys prey items, since only two species caused 80% mortality on at least one item (Eupholidoptera chabrieri and Rhynocoris iracundus) and mortality due the other species never exceed 60%. Among commercially available species only Adalia bipunctata adults and Chrysoperla carnea larvae were effective, predating the eggs and 1st instar nymphs, respectively. Among the field collected specimens, the orthopteran E. chabrieri and the predatory hemipterans R. iracundus, Nagusta goedelii and Himacerus mirmicoides showed efficacy against 1st instar nymphs, E. chabrieri and R. iracundus showed efficacy against 2nd instar nymphs, whereas only E. chabrieri and N. goedelii predated the eggs. R. iracundus was also tested on the adults and successfully predated them. By identifying some of the species that can exploit H. halys as a suitable prey in southern Europe, the present investigation provides an important contribution for conservation biological control of this pest

Performance of the PADME calorimeter prototype at the DAΦ\PhiNE BTF

The PADME experiment at the DA$\Phi$NE Beam-Test Facility (BTF) aims at searching for invisible decays of the dark photon by measuring the final state missing mass in the process $e^+e^- \to \gamma+ A'$, with $A'$ undetected. The measurement requires the determination of the 4-momentum of the recoil photon, performed using a homogeneous, highly segmented BGO crystals calorimeter. We report the results of the test of a 5$\times$5 crystals prototype performed with an electron beam at the BTF in July 2016

Indoor Carbon Monoxide: A Case Study in England for Detection and Interventions to Reduce Population Exposure

Background. Potential exposure to carbon monoxide (CO) in private homes is largely unquantified. Aim. To estimate prevalence of potential exposure to CO in residential dwellings and describe associated interventions in an inner-city community. Methods. A housing association in London, Hackney Homes, began fitting CO alarms in the 22,831 local authority homes it is responsible for in January 2010. A gas engineer investigated each alarm activation and recorded the information on a standard form. We undertook a cross-sectional study of all 22,831 homes, using data from these forms. Descriptive analysis was performed, including incidence, monthly variation, cause of alarm activation, and actions taken. Results. Between November 2011 and April 2012, 106 incidents were reported. Of these, 34.6% identified an issue with a gas appliance, and 10.6% identified misuse of cooking methods as the cause of activation. Relevant interventions were put in place, including disconnection of the gas appliance and education around cooking methods. Discussion. Little is known about the burden of CO poisoning in residential dwellings. This study provides important information on the path to quantifying population exposure to CO as well as establishing a possible approach to access this key information and realistic interventions to reduce potential exposure

POTENTIAL BENEFITS OF COLOSTRUM IN GASTROINTESTINAL DISEASES

This paper reviews the composition of colostrum and the potebntial preventive and therapeutic use of this "first milk" for treating various gastrointestinal disorders in humans. Colostrum is a complex biological liquid that is rich in antimicrobial peptides, immune-regulanting compounds and growth factors than the subsequent mature milk. The main functions of colostrum are to provide essential nutritional components, strenghten the natural defense system, modulate immune response, balance intestinal microbiota and enhance the growth and repair of several tissues. several studies and clinical trials carried out both in vitro and in vivo on humans and animals suggest the clinical benefits of bovine colostrum (BC) supplementation in gastro-intestinal diseases. Despite the encouraging results, there are no contraindications regarding high dose levels and few side effects of clinical relevance have been reported. In conclusion, in the near future, colostrum-based supplementations may be play a role to synthetic drugs in the prevention and treatment of various gastrointestinal disorders

Algorithms for the on-line travelling salesman

In this paper the problem of efficiently serving a sequence of requests presented in an on-line fashion located at points of a metric space is considered. We call this problem the On-Line Travelling Salesman Problem (OLTSP). It has a variety of relevant applications in logistics and robotics. We consider two versions of the problem. In the first one the server is not required to return to the departure point after all presented requests have been served. For this problem we derive a lower bound on the competitive ratio of 2 on the real line. Besides, a 2.5-competitive algorithm for a wide class of metric spaces, and a 7/3-competitive algorithm for the real line are provided. For the other version of the problem, in which returning to the departure point is required, we present an optimal 2-competitive algorithm for the above mentioned general class of metric spaces. If in this case the metric space is the real line we present a 1.75-competitive algorithm that compares with a \approx 1.64 lower bound

Perancangan Dan Pembuatan Aplikasi Ecommerce Pada Toko Agung Jaya

Perkembangan teknologi pada saat ini telah berkembang secara pesat. Dimana hampir semua kegiatan dapat dilakukan pada dunia maya, misalnya melakukan transaksi pembayaran, pembelian barang, pemesanan tiket, baik tiket pesawat maupun tiket kereta api, dan lainnya.Di jaman sekarang ini penjualan secara online sudah banyak. Hal ini dikarenakan untuk membuka suatu USAha online lebih mudah dan murah dari pada membuka USAha disuatu tempat yang berbentuk bangunan. Selain itu, dengan cara berjualan online orang akan lebih banyak mengetahui barang apa saja yang dijual, karena semua orang dapat melihat tanpa harus mendatangi tempat itu.Berdasarkan hasil pengujian aplikasi yang telah dibuat, aplikasi dapat menampilkan data barang yang dijual beserta promo yang ditawarkan. Selain itu aplikasi ini mempunyai fitur konfirmasi account untuk mengaktifkan account dan kirim detail order

COLON MICROBIAL COMPOSITION IS CORRELATED WITH THE SEVERITY OF COLITIS INDUCED BY 2,4,6-TRINITROBENZESULFONIC ACID IN MICE.

The objective of this study was to evaluate the changes in some bacterial species of colonic microbiota, the clinical signs and the intestinal changes in mice with 2,4,6-trinitrobenzenesulfonic acid (TNBS) induced colitis. CD-1 male mice were randomly divided into three groups and inoculated intrarectally with saline ethanol or TNBS solutions. ethanol and TNBS treatments induced weight loss accompained by mild and severe inflammation of the colon mucosa, respectively. however, TNBS-treated mice displayed significant differences compared to the saline group in terms of disease activity index and histological scoring. Both ethanol and TNBS groups showed an increased prevalence of escherichia coli and Clostridium supp., a decrease in lactobacilli and Bifidobacteria counts, as well as changes in the relative proportions of bacteria in the colon. The results confirm the validity of TNBS treatment to study the mechanism involved in the pathogenesis and progression of inflammatory bowel diseases (IBD) in CD-1 mice. Gut microbiota may become a diagnostic biomarker with therapeutic potential for IBD in the future