2,544 research outputs found

    A Model of the Inter-generational Transmission of Educational Success [Wider Benefits of Learning Research Report No. 10]

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    A model of the intergenerational transmission of educational success

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    Visual Awareness: Enabling Iterative Thinking through Photography

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    This paper presents research results that aid in understanding how photography can become a tool for iterative thinking as a mode of reflection. The research was conducted in three phases. The first consisted of a specific task: after reading assigned materials from different sources, PhD students had to take a photograph as a visual reading-report. In the second phase, all the created images were presented and discussed during class. In the last stage, the students talked about their experience through in-depth interviews. The findings showed that visual awareness linked observation and reflection at the same time, since the students were continually looking for ordinary objects to carry new meanings that were relatable to specific arguments and ideas expressed in the reading materials. Hence, visual awareness is understood in this paper as a mode of visual perception that enables a process of thinking iteratively about a particular topic. The photographic camera was identified as a thinking tool that could be a valuable device to incorporate into educational activities. Finally, in addition to practicing iterative thinking, students expressed feeling engaged and motivated, enjoying this activity, and embracing the challenge

    Finding and Analyzing de novo Mutations in the Exomes of Parent-Offspring Trios of Spontaneous Chiari Malformation Type 1 Patients

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    Chiari Malformation Type 1 (CM1) is a neurodevelopmental disorder that occurs when one of the cerebellar tonsils herniates past the foramen magnum causing headaches, motor or sensory deficits, sleep apnea, and difficulty swallowing. This disorder is estimated to affect 1% of the population but due to the need of neuroimaging for diagnosis and the presence of asymptomatic patients there is still uncertainty about the exact proportion of the population affected. CM1 often presents itself with other neurodevelopmental disorders such as syringomyelia, scoliosis, and known genetic syndromes such as Klippel-Feil and Marfan syndromes. Twin, family, and familial clustering studies have established a genetic component to CM1 etiology, but have failed to ascertain any specific causal gene. The difficulty ascertaining causal genes, its comorbidity with multiple different syndromes, and the complex symptomatology of its patients indicate genetic heterogeneity. Other neurodevelopmental disorders with genetic heterogeneity such as Autism Spectrum Disorder and Epileptic Encephalopathies have had success finding genes of interests by looking for de novo mutants (DNMs) from spontaneous patient trios. With this in mind, we sequenced the exomes of a cohort of 29 offspring-parent trios affected with CM1 in search of candidate causative DNMs. Using previously established methods that predict which variants in the exome are DNMs, we found 44 variants that passed multiple filtering steps for quality, likelihood of being real DNMs, and potential to be causative. Three of these variants were classified as stopgain which made them likelier to be detrimental. These three were validated and analyzed for their potential role in CM1 risk. From thousands of possible variants, we successfully obtained a shortlist of genes to further study in future studies

    Visual Awareness: Enabling Iterative Thinking through Photography

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    This paper presents research results that aid in understanding how photography can become a tool for iterative thinking as a mode of reflection. The research was conducted in three phases. The first consisted of a specific task: after reading assigned materials from different sources, PhD students had to take a photograph as a visual reading-report. In the second phase, all the created images were presented and discussed during class. In the last stage, the students talked about their experience through in-depth interviews. The findings showed that visual awareness linked observation and reflection at the same time, since the students were continually looking for ordinary objects to carry new meanings that were relatable to specific arguments and ideas expressed in the reading materials. Hence, visual awareness is understood in this paper as a mode of visual perception that enables a process of thinking iteratively about a particular topic. The photographic camera was identified as a thinking tool that could be a valuable device to incorporate into educational activities. Finally, in addition to practicing iterative thinking, students expressed feeling engaged and motivated, enjoying this activity, and embracing the challenge

    Reutilización del agua residual tratada en la Unidad Académica Profesional Amecameca de la UAEM en la producción de Cyprinus carpio specularis para consumo humano

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    El proyecto iniciado en julio de 2004 y finalizado en noviembre de 2005 consistió en utilizar el agua proveniente de la planta de tratamiento de la Unidad Académica Profesional Amecameca (UAPA) de la Universidad Autónoma del Estado de México (UAEM), que tiene un proceso anaerobio - aerobio - electrofloculación, para la producción de carpa (Cyprinuscarpio specularis), utilizando concentraciones de agua en proporciones del 10 % (de agua tratada), midiendo constantemente los factores físico-químicos (DBO5, DQO, OD, NH3, NO2 -, NO3 -, pH, Conductividad, temperatura, sólidos suspendidos, sólidos disueltos, turbidez,) y biológicos (coliformes totales y coliformes fecales). Un aspecto más que se promovió en el estudio fue la elaboración de raciones alimenticias con maíz de los campos de cultivo y lombrices producidas en la UAPA además de alimento para aves Se concluyó que al utilizar agua reciclada los peces que se obtuvieron en esta producción son aptos para el consumo humano de acuerdo con la Norma Oficial Mexicana (NOM-112- SSA1-1994,; sin embargo, no se obtuvo la reproducción que se obtendría con en agua corriente cuyos parámetros son los idóneos). Los análisis reportaron los siguientes parásitos de los peces (Lernaea cyprinacea) y piojo acuático (Argulus sp), además se aisló un bacilo Gram Negativo identificado como Shigella boydii En cuanto a la dieta bajo el régimen utilizado y cubriendo las necesidades básicas para la producción de la carpa común se obtuvieron ganancias de peso de enero a julio de 2005 teniendo como mínimo de 35 g. y un máximo de 45 g. Los resultados demuestran una ligera ganancia de peso en las carpas alimentadas con maíz - harina de lombriz , pero al realizar el análisis de varianza éste indica que no hubo diferencia significativa entre las tres dietas, por lo tanto se concluye que al suministrar cualquiera de las tres dietas se obtendrán las mismas ganancias de peso

    Visual Perceptual Difficulties and Under-Achievement at School in a Large Community-Based Sample of Children

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    Difficulties with visual perception (VP) are often described in children with neurological or developmental problems. However, there are few data regarding the range of visual perceptual abilities in populations of normal children, or on the impact of these abilities on children's day-to-day functioning. Methods Data were obtained for 4512 participants in an ongoing birth cohort study (Avon Longitudinal Study of Parents and Children; ALSPAC). The children's mothers responded to questions designed to elicit indications of visual perceptual difficulties or immaturity, when their children were aged 13 years. We examined associations with standardised school test results in reading and in mathematics at age 1314 years (SATS-KS3), accounting for potential confounders including IQ. Results Three underlying factors explained half the variance in the VP question responses. These correlated best with questions on interpreting cluttered scenes; guidance of movement and face recognition. The adjusted parameter estimates (95% CI) for the cluttered-scenes factor (0.05; 0.02 to 0.08; p<0.001) suggested positive associations with the reading test results whilst that for the guidance-of-movement factor (0.03; 0.00 to 0.06; p = 0.026) suggested positive association with the mathematics results. The raw scores were associated with both test results. Discussion VP abilities were widely distributed in this sample of 13-year old children. Lower levels of VP function were associated with under-achievement in reading and in mathematics. Simple interventions can help children with VP difficulties, so research is needed into practicable, cost-effective strategies for identification and assessment, so that support can be targeted appropriately

    Association between grain yield, grain quality and morpho-physiological traits along ten cycles of recurrent selection in bread wheat (triticum aestivum L.)

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    The objective of the present investigation was to examine the relationships between agronomical behavior and grain quality along ten cycles of a recurrent selection program performed under rainfed condition. Twenty-four lines, four for each one of the 0, 2, 4, 6, 8 and 10 cycles of recurrent selection, were evaluated for two consecutive years (2011 and 2012). The experimental lines were evaluated under conventional (CT) and no tillage (NT) systems. Grain yield and grain weight were determined and harvest index and grain number estimated. Flour protein content, sodium dodecyl sulphate sedimentation (IS-SDS) and lactic acid SRC (LASRC) were considered as end-use quality predictive tests. The Spearman correlation coefficient was used to measure the relationships among yield, its components and grain quality parameters. Within the context of CT, flour protein content was negatively associated with all the agronomic variables. The IS-SDS has a negative association with the grain weight; meanwhile, LASRC associated positively with all the agronomic variables. When wheat was grown in NT, the relationship between IS-SDS and harvest index, like LASRC with all agronomic traits, was positive. Confining the discussion to the CT results, after ten cycles of recurrent selection the highest grain yield achieved was accompanied by a decrease in protein percentage. However, the decrease in the percentage of protein in more advanced selection cycles was offset by an improvement of its quality.Fil: Maich, Ricardo Héctor. Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias; ArgentinaFil: Steffolani, Maria Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Ciencia y Tecnología de Alimentos Córdoba; ArgentinaFil: Di Rienzo, Julio Alejandro. Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias; ArgentinaFil: Leon, Alberto Edel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Ciencia y Tecnología de Alimentos Córdoba; Argentin
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