100 research outputs found

    Lock-in thermography as an analytical tool for magnetic nanoparticles: measuring heating power and magnetic fields

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    Magnetic nanoparticles and their ability to convert electromagnetic energy into heat are of explicit interest for various applications. However, precise quantification of their heating efficiency is not always upfront, and several parameters render comparative studies challenging. This paper describes the theory behind lock-in thermography, a new technique for quantifying the heating properties of magnetic nanoparticles. This technique allows the investigation of some of the potential sources of variability: key factors such as magnetic field inhomogeneity and its effects on the heating power are explored in detail. The presented results, obtained from various nanoparticle batches of different origins, highlight the importance of pursuing a standardized and systematic approach when quantifying the heating efficiency of magnetic nanoparticles

    A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency.

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    PURPOSE: Patients with primary immunodeficiency (PID) are at risk of serious complications. However, data on the incidence and causes of emergency hospital admissions are scarce. The primary objective of the present study was to describe emergency hospital admissions among patients with PID, with a view to identifying "at-risk" patient profiles. METHODS: We performed a prospective observational 12-month multicenter study in France via the CEREDIH network of regional PID reference centers from November 2010 to October 2011. All patients with PIDs requiring emergency hospital admission were included. RESULTS: A total of 200 admissions concerned 137 patients (73 adults and 64 children, 53% of whom had antibody deficiencies). Thirty admissions were reported for 16 hematopoietic stem cell transplantation recipients. When considering the 170 admissions of non-transplant patients, 149 (85%) were related to acute infections (respiratory tract infections and gastrointestinal tract infections in 72 (36%) and 34 (17%) of cases, respectively). Seventy-seven percent of the admissions occurred during winter or spring (December to May). The in-hospital mortality rate was 8.8% (12 patients); death was related to a severe infection in 11 cases (8%) and Epstein-Barr virus-induced lymphoma in 1 case. Patients with a central venous catheter (n = 19, 13.9%) were significantly more hospitalized for an infection (94.7%) than for a non-infectious reason (5.3%) (p = 0.04). CONCLUSION: Our data showed that the annual incidence of emergency hospital admission among patients with PID is 3.4%. The leading cause of emergency hospital admission was an acute infection, and having a central venous catheter was associated with a significantly greater risk of admission for an infectious episode

    Engraissement de taurillons et de mâles adultes de race Gobra à partir de sous-produits agro-industriels mélasses au Sénégal

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    Fattening of bull calves and adult males of Gobra with agroindustrial products such as molasses in Senegal. This document presents the results of a research carried out in Senegal with the aim to achieve low cost rations which can be prepared in suburban areas which are generally poor in fibrous sub-products. The economic success of the productions is conditionned by the choice and the purchase and sales price of the animals. The adjustement of the quantifies of feed distributed considering the quality of the diet and the growth potential of the animals also determine the profits made. The experiments carried out enable the authors to make recommandations about the development of fattening trials depending on the different degrees of intensification and to trace the research axes which need to be pursued in this field

    Characterization of the novel HLA-C*06:311 allele by sequencing-based typing

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    HLA-C*06:311 differs from HLA-C*06:02:01:01 by one nucleotide substitution in codon 43 in exon 2

    Characterization of the novel HLA-B*14:01:13 allele by sequencing-based typing

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    HLA-B*14:01:13 differs from HLA-B*14:01:01:01 by one nucleotide substitution in codon 79 in exon 2

    Characterization of the novel HLA-A*26:01:66 allele by sequencing-based typing

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    HLA-A*26:01:66 differs from HLA-A*26:01:01:01 by a single nucleotide change in codon 41 in exon 2
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