Accurate Calibration of the Velocity-dependent One-scale Model for Domain Walls

We study the asymptotic scaling properties of standard domain wall networks in several cosmological epochs. We carry out the largest field theory simulations achieved to date, with simulation boxes of size 20483, and confirm that a scale-invariant evolution of the network is indeed the attractor solution. The simulations are also used to obtain an accurate calibration for the velocity-dependent one-scale model for domain walls: we numerically determine the two free model parameters to have the values $c_w = 0.34\pm0.16$ and $k_w = 0.98\pm0.07$, which are higher precision than (but in agreement with) earlier estimates.Comment: 8 pages, version to appear in Phys. Lett. B. arXiv admin note: substantial text overlap with arXiv:1110.348

Hyperfine spectroscopy of hydrogen and antihydrogen in ASACUSA

The ASACUSA collaboration at the Antiproton Decelerator of CERN aims at a precise measurement of the antihydrogen ground-state hyperfine structure as a test of the fundamental CPT symmetry. A beam of antihydrogen atoms is formed in a CUSP trap, undergoes Rabi-type spectroscopy and is detected downstream in a dedicated antihydrogen detector. In parallel measurements using a polarized hydrogen beam are being performed to commission the spectroscopy apparatus and to perform measurements of parameters of the Standard Model Extension (SME). The current status of antihydrogen spectroscopy is reviewed and progress of ASACUSA is presented.Comment: Proceedings of the 7th International Syposium on Symmetries in Subatomic Physics SSP2018, Aachen (Germany), 10 - 15 Jun 2018. Corrected error in Fig. 1, updated caption, add titles to reference

Ion recombination correction factors and detector comparison in a very-high dose rate proton scanning beam

International audienceAccurate dosimetry is paramount to study the FLASH biological effect since dose and dose rate are critical dosimetric parameters governing its underlying mechanisms. With the goal of assessing the suitability of standard clinical dosimeters in a very-high dose rate (VHDR) experimental setup, we evaluated the ion collection efficiency of several commercially available air-vented ionization chambers (IC) in conventional and VHDR proton irradiation conditions. Methods: A cyclotron at the Orsay Proton Therapy Center was used to deliver VHDR pencil beam scanning irradiation. Ion recombination correction factors (k s) were determined for several detectors (Advanced Markus, PPC05, Nano Razor, CC01) at the entrance of the plateau and at the Bragg peak, using the Niatel model, the Twovoltage method and Boag's analytical formula for continuous beams. Results: Mean dose rates ranged from 4 Gy/s to 385 Gy/s, and instantaneous dose rates up to 1000 Gy/s were obtained with the experimental setup. Recombination correction factors below 2 % were obtained for all chambers, except for the Nano Razor, at VHDRs with variations among detectors, while k s values were significantly smaller (0.8 %) for conventional dose rates. Conclusions: While the collection efficiency of the probed ICs in scanned VHDR proton therapy is comparable to those in the conventional regime with recombination coefficiens smaller than 1 % for mean dose rates up to 177 Gy/s, the reduction in collection efficiency for higher dose rates cannot be ignored when measuring the absorbed dose in pre-clinical proton scanned FLASH experiments and clinical trials

Hepatic damage during acute pancreatitis in the rat

We studied the alterations in the metabolism of liver mitochondria in rats with acute pancreatitis. Male Wistar rats were allocated to a control group (group I) and to five other groups corresponding to 2, 4, 12, 24 and 48 h after the induction of acute pancreatitis by the injection of 5% sodium taurocholate into the pancreatic duct. Sham-operated animals were submitted to the same surgical steps except for the induction of acute pancreatitis. Mitochondrial oxidation and phosphorylation were measured polarographically by determining oxygen consumption without ADP (basal respiration, state 4) and in the presence of ADP (activated respiration, state 3). Serum amylase, transaminases (ALT and AST) and protein were also determined. Ascitic fluid, contents of amylase, trypsin and total protein were also determined and arterial blood pressure was measured in all groups. In ascitic fluid, trypsin and amylase increased reaching a maximum at 2 and 4 h, respectively. Serum amylase increased at 2 h reaching a maximum at 4 h. Serum transaminase levels increased at 12 and 24 h. After 2 h (and also 4 h) there was an increase in state 4 respiration (45.65 ± 1.79 vs 28.96 ± 1.50) and a decrease in respiration control rate (3.53 ± 0.09 vs 4.45 ± 0.08) and in the ADP/O ratio (1.77 ± 0.02 vs 1.91 ± 0.01) compared to controls (P<0.05). These results indicate a disruption of mitochondrial function, which recovered after 12 h. In the 48-h groups there was mitochondrial damage similar to that occurring in ischemic lesion. Beat-to-beat analysis (30 min) showed that arterial blood pressure remained normal up to 24 h (111 ± 3 mmHg) while a significant decrease occurred in the 48-h group (91 ± 4 mmHg). These data suggest biphasic damage in mitochondrial function in acute pancreatitis: an initial uncoupled phase, possibly secondary to enzyme activity, followed by a temporary recovery and then a late and final dysfunction, associated with arterial hypotension, possibly related to ischemic damage

Hyperfine spectroscopy of hydrogen and antihydrogen in ASACUSA

The ASACUSA collaboration at the Antiproton Decelerator of CERN aims at a precise measurement of the antihydrogen ground-state hyperfine structure as a test of the fundamental CPT symmetry. A beam of antihydrogen atoms is formed in a CUSP trap, undergoes Rabi-type spectroscopy and is detected downstream in a dedicated antihydrogen detector. In parallel measurements using a polarized hydrogen beam are being performed to commission the spectroscopy apparatus and to perform measurements of parameters of the Standard Model Extension (SME). The current status of antihydrogen spectroscopy is reviewed and progress of ASACUSA is presented

Positron production using a 9 MeV electron linac for the GBAR experiment

International audienceFor the GBAR (Gravitational Behaviour of Antihydrogen at Rest) experiment at CERN’s Antiproton Decelerator (AD) facility we have constructed a source of slow positrons, which uses a low-energy electron linear accelerator (linac). The driver linac produces electrons of 9 MeV kinetic energy that create positrons from bremsstrahlung-induced pair production. Staying below 10 MeV ensures no persistent radioactive activation in the target zone and that the radiation level outside the biological shield is safe for public access. An annealed tungsten-mesh assembly placed directly behind the target acts as a positron moderator. The system produces 5×107 slow positrons per second, a performance demonstrating that a low-energy electron linac is a superior choice over positron-emitting radioactive sources for high positron flux

A pulsed high-voltage decelerator system to deliver low-energy antiprotons

The GBAR (Gravitational Behaviour of Antihydrogen at Rest) experiment at CERN requires efficient deceleration of 100 keV antiprotons provided by the new ELENA synchrotron ring to synthesize antihydrogen. This is accomplished using electrostatic deceleration optics and a drift tube that is designed to switch from -99 kV to ground when the antiproton bunch is inside - essentially a charged-particle “elevator” - producing a 1 keV pulse. We describe the simulation, design, construction and successful testing of the decelerator device at -92 kV on-line with ELENA