Seniority-based entitlements : extent, policy debates and research

Aquesta publicació s'elabora a partir de les contribucions de cadascú dels membres nacionals que integren la Network of Eufound Correspondent. Pel cas d'Espanya la contribució ha estat realitzada per l'Oscar MolinaSeniority systems - schemes that allot improving employment rights or benefits to employees as their length of employment increases - have not been widely studied. This report provides the first comprehensive study comparing the design and spread of seniority-based entitlements (SBEs) in Europe and mapping related policy debates. It is primarily based on contributions from the Network of Eurofound Correspondents, covering the 28 EU Member States and Norway, but also presents aggregate seniority-earnings curves for the EU based on data from the Structure of Earnings Survey. The aim of the report is to take stock of the currently existing different types of SBEs in the private and public sectors. It concludes that despite an obvious trend to remove them from regulations or reform them, a substantial amount of such entitlements is here to stay. Paradoxically, countries which have regulations on seniority pay in place tend to have flatter aggregate seniority-earnings curves than countries without such regulations

Choc septique et mise en place d'un essai clinique visant à évaluer sa thérapeutique

PARIS-BIUP (751062107) / SudocSudocFranceF

Guide d’utilisation des bases de données sol pour la production de cartes thématiques

Guide d’utilisation des bases de données sol pour la production de cartes thématique

Projet Géoportail : Porter à connaissance de données sol issues du programme IGCS, Volet Référentiel Régional Pédologique (RRP), sur le Géoportail

National audienc

Diffusion des référentiels régionaux pédologiques sous la forme d'une carte des sols dominants (France métropolitaine - Hors Corse) accessible sur le Géoportail

International audienceCet article présente la méthode employée pour créer la carte des sols dominants de France métropolitaine (hors Corse). Cette carte est produite à partir des Référentiels Régionaux Pédologiques d’échelle 1/250 000 issus du programme Inventaire, Gestion et Conservation des Sols (IGCS). Elle est publiée en visualisation sur le Géoportail de l’Institut national de l’information géographique et forestière (IGN). Cette infrastructure, de par sa visibilité nationale, est à même de toucher un large public non-initié à la pédologie et de permettre de porter à connaissance les bases de données sols couvrant la quasi-totalité du territoire métropolitain. Cette première publication de données sol sur le Géoportail constitue une porte d’entrée permettant d’avoir un aperçu des grands types de sols dominants d’un périmètre et d’identifier les organismes contacts dans les territoires pour pouvoir accéder à toute la richesse d’informations disponibles sur les sols. Cette initiative devrait être suivie par la publication d’autres données sur les sols sur le Géoportail

Design and conduct of the activated protein C and corticosteroids for human septic shock (APROCCHSS) trial

International audienceBACKGROUND:We aimed at assessing the benefit-to-risk ratio of activated protein C (drotrecogin-alfa activated, DAA) and corticosteroids, given alone or in combination, in patients with septic shock.METHODS:We implemented an investigator-led, publicly funded, multicenter, randomized according to a 2 × 2 factorial design, placebo-controlled, double-blind trial in four parallel groups in which adults with persistent septic shock and no contraindication to DAA were assigned to either DAA alone (24 mg/kg/h for 96 h), or hydrocortisone (50 mg intravenous bolus q6 for 7 days) and fludrocortisone (50 µg once daily through the nasogastric tube for 7 days) alone, or their respective combinations, or their respective placebos. Primary endpoint was 90-day mortality rate. Follow-up duration was 6 months. Statistical analysis was planned to be performed in intent-to-treat once after all participants completed 180-day follow-up and according to the 2 × 2 factorial design.RESULTS:The first patient was recruited in September 2008. The trial was suspended on October 25, 2011, owing to the withdrawal from the market of DAA. At this time, 411 patients had been enrolled. On May 17, 2012, the continuation of the trial on two parallel groups was approved by all legal authorities with the aim of investigating the benefit-to-risk ratio of corticosteroids. On June 30, 2014, the trial was suspended again by the study sponsor upon request of the independent data and safety monitoring board. Recruitment restarted on October 7, 2014, after any safety concern was ruled out. Finally, the trial was completed on June 23, 2015, with the recruitment of 1241 patients.CONCLUSIONS:This report details the design, statistical plan and conduct of a randomized controlled trial of hydrocortisone and fludrocortisone in septic shock. Trial registration The trial was registered at ClinicalTrials.gov under NCT00625209

Les sols dominants en France métropolitaine: Descriptions des grandes familles de sols

Ce document présente les différents grands types de sol présents en France métropolitaine d'après la carte des sols dominants de France