Modern shaping suit in the learning process of designers on the basis of the traditional costume of Belgorod region

The article presents the connection of fine, decorative and folk art in order for art education and aesthetic education of students on folk traditionsВ статье представлена связь изобразительного, декоративно-прикладного и народного искусства в целях художественного образования и эстетического воспитания студентов на народных традиция

Bad expression influences time to androgen escape in prostate cancer

<b>OBJECTIVE</b>: To assess the role of selected downstream Bcl-2 family members (Bad, Bax, Bcl-2 and Bcl-xL) in the development of androgen-independent prostate cancer (AIPC), as androgen-deprivation therapy is the treatment of choice in advanced prostate cancer, yet patients generally relapse and progress to an AI state within 18–24 months. <b>PATIENTS, MATERIALS AND METHODS</b>: The patient cohort was established by retrospectively selecting patients with prostate cancer who had an initial response to androgen-deprivation therapy, but subsequently relapsed with AIPC. In all, 58 patients with prostate cancer were included with matched androgen-dependent (AD) and AI prostate tumours available for immunohistochemical analysis; two independent observers using a weighted-histoscore method scored the staining. Changes in Bad, Bax, Bcl-2 and Bcl-xL expression during transition to AIPC were evaluated and then correlated to known clinical variables. <b>RESULTS</b>: High Bad expression in AD tumours was associated with an increased time to biochemical relapse (<i>P</i> = 0.007) and a trend towards improved overall survival (<i>P</i> = 0.053). There were also trends towards a decrease in Bad (<i>P</i> = 0.068) and Bax (<i>P</i> = 0.055) expression with progression to AIPC. There were no significant results for Bcl-2 or Bcl-xL. <b>CONCLUSION</b>: There is evidence to suggest that Bad expression levels at diagnosis influence time to biochemical relapse and overall survival, and that levels of pro-apoptotic proteins Bad and Bax fall during AIPC development. Bad might therefore represent a possible positive prognostic marker and potential therapeutic target for AIPC in the future

Species of Fungi in the Root System of Woody Plants in Urban Plantations

The features of the species composition of microscopic fungi in the root system and rhizosphere soil of woody plants in connection with the level of soil contamination have not been studied sufficiently. This article presents the results of studying the species composition of fungi in the root system and soil of three species of woodyplants (Acer negundo L., Acer platanoides L., and Betula pendula Roth.) growing in urban plantations of various ecological categories with different levels of heavy metal soil contamination. The study was carried out in a large industrial center of the Urals region, Izhevsk. When studying the species composition of fungi, microscopyand molecular genetic analysis were used. Isolates of endotrophic fungi from the root system of plants were isolated, and systematic membership was determined by molecular genetic analysis. The results showed that in soils with a high level of contamination, the DNA of endotrophic mycorrhiza-forming fungi was found in theroots of woody plants in a good living state. Keywords: fungi, heavy metals, plantations, urban environment, resistanc

Influence of the preparation method on planar perovskite CH3NH3PbI3-xClx solar cell performance and hysteresis

The present research has been supported by the State Research Programme “LATENERGI” and National Research Programme “Multifunctional Materials and Composites, Photonics and Nanotechnology (IMIS2)”.Organometal halide perovskites are promising materials for lowcost, high-efficiency solar cells. The method of perovskite layer deposition and the interfacial layers play an important role in determining the efficiency of perovskite solar cells (PSCs). In the paper, we demonstrate inverted planar perovskite solar cells where perovskite layers are deposited by two-step modified interdiffusion and one-step methods. We also demonstrate how PSC parameters change by doping of charge transport layers (CTL). We used dimethylsupoxide (DMSO) as dopant for the hole transport layer (PEDOT:PSS) but for the electron transport layer [6,6]-phenyl C61 butyric acid methyl ester (PCBM)) we used N,N-dimethyl-N-octadecyl(3-aminopropyl)trimethoxysilyl chloride (DMOAP). The highest main PSC parameters (PCE, EQE, VOC) were obtained for cells prepared by the one-step method with fast crystallization and doped CTLs but higher fill factor (FF) and shunt resistance (Rsh) values were obtained for cells prepared by the two-step method with undoped CTLs.Institute of Solid State Physics, University of Latvia as the Center of Excellence has received funding from the European Union’s Horizon 2020 Framework Programme H2020-WIDESPREAD-01-2016-2017-TeamingPhase2 under grant agreement No. 739508, project CAMART

The role of RIG-I, AIM2 and IFI16 receptors for viral RNA and DNA in the pathogenesis of spontaneous and early missed miscarriage

Aim: to identify the features of the expression of mRNA of intracellular RIG-I, IFI16 and AIM2 receptors for viral RNA and DNA, and their signaling pathway proteins in the decidual tissue of patients with spontaneous and early missed miscarriage

Structure and energetics of carbon, hexagonal boron nitride and carbon/hexagonal boron nitride single-layer and bilayer nanoscrolls

Single-layer and bilayer carbon and hexagonal boron nitride nanoscrolls as well as nanoscrolls made of bilayer graphene/hexagonal boron nitride heterostructure are considered. Structures of stable states of the corresponding nanoscrolls prepared by rolling single-layer and bilayer rectangular nanoribbons are obtained based on the analytical model and numerical calculations. The lengths of nanoribbons for which stable and energetically favorable nanoscrolls are possible are determined. Barriers to rolling of single-layer and bilayer nanoribbons into nanoscrolls and barriers to nanoscroll unrolling are calculated. Based on the calculated barriers nanoscroll lifetimes in the stable state are estimated. Elastic constants for bending of graphene and hexagonal boron nitride layers used in the model are found by density functional theory calculations.Comment: 9 pages, 6 figure

Development of the basic soil classification of Vladimir Fridland in the classification of soils of Russia 2004/2008

The basic three-component classification system of soils of the world was published by V.M. Fridland in 1982, and its profile-genetic component was taken as a basis for the classification of soils of Russia (1997– 2004–2008). Unlike the former systems, in that of Fridland the priority is given to soil properties, and this conceptual background is transferred into the new Russian system. The substantive-genetic principles of both systems are implemented in diagnostic horizons and genetic properties; both systems have similar hierarchy of taxa, nomenclature, keys. Changes introduced in the classification of soils of Russia derive either of proposals forwarded in the course of its application, or of information accumulated. They concern the improvement of definitions and introduction of new diagnostic elements; however, the main principles are preserved in the existing and forthcoming versions

Magnetically operated nanorelay based on two single-walled carbon nanotubes filled with endofullerenes Fe@C20

Structural and energy characteristics of the smallest magnetic endofullerene Fe@C20 have been calculated using the density functional theory approach. The ground state of Fe@C20 is found to be a septet state, and the magnetic moment of Fe@C20 is estimated to be 8 Bohr magnetons. Characteristics of an (8,8) carbon nanotube with a single Fe@C20 inside are studied in the framework of the semiempirical approach. The scheme of a magnetic nanorelay based on cantilevered nanotubes filled with magnetic endofullerenes is elaborated. The proposed nanorelay is turned on as a result of bending of nanotubes by a magnetic force. Operational characteristics of such a nanorelay based on (8,8) and (21,21) nanotubes fully filled with Fe@C20 are estimated and compared to the ones of a nanorelay made of a (21,21) nanotube fully filled with experimentally observed (Ho3N)@C80 with the magnetic moment of 21 Bohr magnetons. Room temperature operation of (21,21) nanotube based nanorelays is shown.Comment: 18 pages, 9 figure