2,551 research outputs found
Effects of sidewall geometry on the installed performance of nonaxisymmetric convergent-divergent exhaust nozzles
The investigation was conducted at static conditions and over a Mach number range from 0.6 to 1.2. Angle of attack was held constant at 0 deg. High pressure air was used to simulate jet exhaust flow at ratios of jet total pressure to free-stream static pressure from 1 (jet off) to approximately 10. Sidewall cutback appears to be a viable way of reducing nozzle weight and cooling requirements without compromising installed performance
Addition of H_2O and O_2 to Acetone and Dimethylsulfoxide Ligated Uranyl(V) Dioxocations
Gas-phase complexes of the formula [UO_2(lig)]^+ (lig = acetone (aco) or dimethylsulfoxide (dmso)) were generated by electrospray ionization (ESI) and studied by tandem ion-trap mass spectrometry to determine the general effect of ligand charge donation on the reactivity of UO_2^+ with respect to water and dioxygen. The original hypothesis that addition of O_2 is enhanced by strong σ-donor ligands bound to UO_2^+ is supported by results from competitive collision-induced dissociation (CID) experiments, which show near exclusive loss of H_2O from [UO_2(dmso)(H_2O)(O_2)]^+, whereas both H_2O and O_2 are eliminated from the corresponding [UO_2(aco)(H_2O)(O_2)]^+ species. Ligand-addition reaction rates were investigated by monitoring precursor and product ion intensities as a function of ion storage time in the ion-trap mass spectrometer: these experiments suggest that the association of dioxygen to the UO_2^+ complex is enhanced when the more basic dmso ligand was coordinated to the metal complex. Conversely, addition of H_2O is favored for the analogous complex ion that contains an aco ligand. Experimental rate measurements are supported by density function theory calculations of relative energies, which show stronger bonds between UO_2^+ and O_2 when dmso is the coordinating ligand, whereas bonds to H_2O are stronger for the aco complex
Inelastic Diffraction and Spectroscopy of Very Weakly Bound Clusters
We study the coherent inelastic diffraction of very weakly bound two body
clusters from a material transmission grating. We show that internal
transitions of the clusters can lead to new separate peaks in the diffraction
pattern whose angular positions determine the excitation energies. Using a
quantum mechanical approach to few body scattering theory we determine the
relative peak intensities for the diffraction of the van der Waals dimers
(D_2)_2 and H_2-D_2. Based on the results for these realistic examples we
discuss the possible applications and experimental challenges of this coherent
inelastic diffraction technique.Comment: 15 pages + 5 figures. J. Phys. B (in press
Influence of Sex/Gender and Race on Responses to Raltegravir Combined With Tenofovir-Emtricitabine in Treatment-Naive Human Immunodeficiency Virus-1 Infected Patients: Pooled Analyses of the STARTMRK and QDMRK Studies.
BACKGROUND: Antiretroviral therapy in human immunodeficiency virus (HIV)-infected women and blacks merits particular scrutiny because these groups have been underrepresented in clinical trials.
METHODS: To document the effects of raltegravir across sex and racial lines, we conducted a pooled subgroup analysis of the efficacy and safety of raltegravir 400 mg BID plus tenofovir-emtricitabine by sex (women vs men) and self-identified race (black vs non-black) using phase 3 studies in treatment-naive patients.
RESULTS: Study participants included 42 black women, 102 non-black women, 48 black men, and 477 non-black men. Clade B infections were less common in women (43.8%) than men (84.6%) and in blacks (45.6%) than non-blacks (80.5%). Baseline CD4 counts were ≤200 cells/µL in 52.2% of blacks and 31.6% of non-blacks. Black men had the largest proportion of patients with baseline CD4 counts/µL and the highest nontreatment-related discontinuation rate among the 4 sex-by-race subgroups. Human immunodeficiency virus-ribonucleic acid levels/mL were achieved at week 48 in 92.7% (95% confidence interval [CI], 80.1-98.5) of black women, 93.6% (95% CI, 86.6-97.6) of non-black women, 82.9% (95% CI, 67.9-92.8) of black men, and 91.4% (95% CI, 88.4-93.8) of non-black men. Serious clinical adverse events were reported in 9.0% of women versus 8.8% of men and in 11.1% of blacks versus 8.5% of non-blacks.
CONCLUSIONS: In this post hoc analysis of patients with previously untreated HIV-1 infection receiving raltegravir plus tenofovir-emtricitabine, generally comparable results were achieved across sex and racial subgroups. However, black men had a lower response rate than either black women or non-black men, partially attributable to lower baseline CD4 counts and higher discontinuation rates
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Using Tree Rings to Predict the Response of Tree Growth to Climate Change in the Continental United States during the Twenty-First Century
In the early 1900s, tree-ring scientists began analyzing the relative widths of annual growth rings preserved in the cross sections of trees to infer past climate variations. Now, many ring-width index (RWI) chronologies, each representing a specific site and species, are archived online within the International Tree-Ring Data Bank (ITRDB). Comparing annual tree-ring-width data from 1097 sites in the continental United States to climate data, the authors quantitatively evaluated how trees at each site have historically responded to interannual climate variations. For each site, they developed a climate-driven statistical growth equation that uses regional climate variables to model RWI values. The authors applied these growth models to predict how tree growth will respond to twenty-first-century climate change, considering four climate projections. Although caution should be taken when extrapolating past relationships with climate into the future, the authors observed several clear and interesting patterns in the growth projections that seem likely if warming continues. Most notably, the models project that productivity of dominant tree species in the southwestern United States will decrease substantially during this century, especially in warmer and drier areas. In the northwest, nonlinear growth relationships with temperature may lead to warming-induced declines in growth for many trees that historically responded positively to warmer temperatures. This work takes advantage of the unmatched temporal length and spatial breath of annual growth data available within the ITRDB and exemplifies the potential of this ever-growing archive of tree-ring data to serve in meta-analyses of large-scale forest ecology
Distraction from pain and executive functioning: an experimental investigation of the role of inhibition, task switching and working memory
Although many studies have investigated the effectiveness of distraction as a method of pain control, the cognitive processes by which attentional re-direction is achieved, remain unclear. In this study the role of executive functioning abilities (inhibition, task switching and working memory) in the effectiveness of distraction is investigated. We hypothesized that the effectiveness of distraction in terms of pain reduction would be larger in participants with better executive functioning abilities. Ninety-one undergraduate students first performed executive functioning tasks, and subsequently participated in a cold pressor task (CPT). Participants were randomly assigned to (1) a distraction group, in which an attention-demanding tone-detection task was performed during the CPT, or (2) a control group, in which no distraction task was performed. Participants in the distraction group reported significantly less pain during the CPT, but the pain experience was not influenced by executive functioning abilities. However, the performance on the distraction task improved with better inhibition abilities, indicating that inhibition abilities might be important in focussing on a task despite the pain
A Very Low Resource Language Speech Corpus for Computational Language Documentation Experiments
Most speech and language technologies are trained with massive amounts of
speech and text information. However, most of the world languages do not have
such resources or stable orthography. Systems constructed under these almost
zero resource conditions are not only promising for speech technology but also
for computational language documentation. The goal of computational language
documentation is to help field linguists to (semi-)automatically analyze and
annotate audio recordings of endangered and unwritten languages. Example tasks
are automatic phoneme discovery or lexicon discovery from the speech signal.
This paper presents a speech corpus collected during a realistic language
documentation process. It is made up of 5k speech utterances in Mboshi (Bantu
C25) aligned to French text translations. Speech transcriptions are also made
available: they correspond to a non-standard graphemic form close to the
language phonology. We present how the data was collected, cleaned and
processed and we illustrate its use through a zero-resource task: spoken term
discovery. The dataset is made available to the community for reproducible
computational language documentation experiments and their evaluation.Comment: accepted to LREC 201
Influence of retardation effects on 2D magnetoplasmon spectrum
Within dissipationless limit the magnetic field dependence of magnetoplasmon
spectrum for unbounded 2DEG system found to intersect the cyclotron resonance
line, and, then approaches the frequency given by light dispersion relation.
Recent experiments done for macroscopic disc-shape 2DEG systems confirm theory
expectations.Comment: 2 pages,2 figure
Variability of Luminous Stars in the Large Magellanic Cloud Using 10 Years of ASAS Data
Motivated by the detection of a recent outburst of the massive luminous blue
variable LMC-R71, which reached an absolute magnitude M_V = -9.3 mag, we
undertook a systematic study of the optical variability of 1268 massive stars
in the Large Magellanic Cloud, using a recent catalog by Bonanos et al. (2009)
as the input. The ASAS All Star Catalog (Pojmanski 2002) provided well-sampled
light curves of these bright stars spanning 10 years. Combining the two
catalogs resulted in 599 matches, on which we performed a variability search.
We identified 117 variable stars, 38 of which were not known before, despite
their brightness and large amplitude of variation. We found 13 periodic stars
that we classify as eclipsing binary (EB) stars, eight of which are newly
discovered bright, massive eclipsing binaries composed of OB type stars. The
remaining 104 variables are either semi- or non-periodic, the majority (85)
being red supergiants. Most (26) of the newly discovered variables in this
category are also red supergiants with only three B and four O stars.Comment: 23 pages, 10 figures and 3 tables; published in A
Tracking system analytic calibration activities for the Mariner Mars 1971 mission
Data covering various planning aspects of Mariner Mars 1971 mission are summarized. Data cover calibrating procedures for tracking stations, radio signal propagation in the troposphere, effects of charged particles on radio transmission, orbit calculation, and data smoothing
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