132 research outputs found
Propuesta de mejoramiento y ampliación de servicios en el área de metalmecánica para “Talleres Benenaula”
Para el desarrollo de este trabajo, basado en la implementación de mejoras productivas en el sector industrial, se efectuó un diagnóstico de la situación actual de la empresa de mecánica de precisión Talleres Benenaula, identificando sus fortalezas y debilidades a nivel productivo; posteriormente se realizó un estudio de mercado para la instauración de nuevos servicios de tratamientos térmicos, incluyendo la fabricación de un prototipo de máquina para tratamiento criogénico y los servicios de mecanizado mediante maquinaria con tecnología de Control Numérico Computarizado (CNC), de acuerdo a los análisis de la demanda insatisfecha. De esta manera se realizó un estudio técnico de los servicios actuales y nuevos, para proponer una reestructuración de la planta actual mediante un rediseño y reubicación adecuados de la planta, para satisfacer sus necesidades actuales y sus nuevos servicios. En la fase final se realizó un estudio económico de la propuesta, en el cual se verificó su viabilidad en costos, ingresos, inversiones y la evaluación financiera
Complete genome sequence of Tessaracoccus sp. Strain T2.5-30 isolated from 139.5 meters deep on the subsurface of the Iberian Pyritic Belt
Here, we report the complete genome sequence of Tessaracoccus sp.
strain T2.5-30, which consists of a chromosome with 3.2 Mbp, 70.4% G C content,
and 3,005 coding DNA sequences. The strain was isolated from a rock core retrieved
at a depth of 139.5 m in the subsurface of the Iberian Pyritic Belt (Spain)This work was supported by the Foundation for Science and Technology (FCT),
Portugal (doctoral fellowship SFRH/BD/87076/2012 to T.L.) and by ERC Advanced grant
IPBSL-25035
Modeling the Dashboard Provenance
Organizations of all kinds, whether public or private, profit-driven or
non-profit, and across various industries and sectors, rely on dashboards for
effective data visualization. However, the reliability and efficacy of these
dashboards rely on the quality of the visual and data they present. Studies
show that less than a quarter of dashboards provide information about their
sources, which is just one of the expected metadata when provenance is
seriously considered. Provenance is a record that describes people,
organizations, entities, and activities that had a role in the production,
influence, or delivery of a piece of data or an object. This paper aims to
provide a provenance representation model, that entitles standardization,
modeling, generation, capture, and visualization, specifically designed for
dashboards and its visual and data components. The proposed model will offer a
comprehensive set of essential provenance metadata that enables users to
evaluate the quality, consistency, and reliability of the information presented
on dashboards. This will allow a clear and precise understanding of the context
in which a specific dashboard was developed, ultimately leading to better
decision-making.Comment: 8 pages, 4 figures, one table, to be published in VIS 2023 (Vis +
Prov) x Domai
Herramientas moleculares aplicadas al estudio de aguas para el consumo humano, comunidad El Cacao, Nicaragua
Se determinó la presencia de contaminantes microbianos en aguas de consumo humano de la comunidad El Cacao, Mosonte, Nueva Segovia. El análisis se realizó tanto por métodos microbiológicos como por vía molecular analizando su interrelación con las enfermedades que se observan en la comunidad. Se obtuvo la presencia de coliformes fecales, totales y Escherichia coli desde la captación hasta el tanque de almacenamiento. Los aislados identificados pertenecen a las bacterias del tipo Alcaligenes y Paenalcaligenes, además de Stenotrophomonas y Serratia. Las cuales son bacterias acuáticas y están asociadas a diversas enfermedades. Además se identificó lapresencia de Aspergillus que han sido bien reportados en diversas enfermedades humanas
Nutritional Status after Roux-En-Y (Rygb) and One Anastomosis Gastric Bypass (Oagb) at 6-Month Follow-Up: A Comparative Study
Introduction: Roux-en-Y gastric bypass (RYGB) and one anastomosis gastric bypass (OAGB) are two effective bariatric surgical procedures with positive outcomes in terms of weight loss, comorbidities remission, and adverse events profiles. OAGB seems to carry a higher risk of malnutrition, but existing data are controversial. The aim of this study is to objectively evaluate and compare malnutrition in patients undergoing RYGB and OAGB. Methods: Retrospective monocentric study of obese patients undergoing RYGB or OAGB between the 15 September 2020 and the 31 May 2021. Nutritional status was assessed using the Controlling Nutritional Status (CONUT) score and compared between groups. The primary outcome was the mean CONUT score at 6 months. The secondary outcomes included the incidence of malnutrition, comorbidities, including hypertension, insulin resistance and type II diabetes mellitus, and weight loss. Results: 78 patients were included: 30 underwent RYGB and 48 underwent OAGB. At 6-Month Follow-Up there was no difference between groups in the mean CONUT score nor in incidence of malnutrition. In both groups, the nutritional status significantly worsened 6 months after surgery (preoperative and postoperative score of 0.48 +/- 0.9 and 1.38 +/- 1.5; p = 0.0066 for RYGB and of 0.86 +/- 1.5 and 1.45 +/- 1.3; p = 0.0422 for OAGB). Type II Diabetes mellitus (DMII) and hypertension remission were significant in the OAGB group with a 100% relative remission in the DMII-OAGB group (p = 0.0265), and a 67% relative remission in the hypertension-OAGB group (p = 0.0031). Conclusions: No difference in nutritional status has been detected between patients undergoing RYGB or OAGB at the 6-Month Follow-Up. Both procedures may have significant mal-absorptive effects leading to decline in nutritional status. OAGB may be more efficacious in inducing DMII and hypertension remission. Larger prospective studies dedicated specifically to nutritional status after gastric bypass are needed to confirm the impact of different bypass procedures on nutritional status
Lymphocyte activation after a high-intensity street dance class
Intense dance training leads to inflammation, which may impair the health and performance of the practitioners. Herein, we evaluate the effect of a single street dancing class on the profile of muscle enzymes, lymphocyte activation, and cell surface CD62L expression. We also investigated the correlation between muscle enzymes, adhesion molecules, and lymphocyte activation in dancers. Fifteen male participants (mean ± standard error: age 22.4 ± 1.08 years, body mass index 24.8 ± 0.69 kg/m2, body fat 12.3 ± 1.52%), who were amateur dancers, had blood samples collected previously and subsequent to a high-intensity street dance class. After the class, dancers showed an increase in total lymphocyte count (2.0-fold), creatine kinase (CK)-NAC (4.87%), and CK-MB (3.36%). We also observed a decrease (2.5-fold) in reactive oxygen species (ROS) produced by lymphocytes, under phorbol myristate acetate-stimulated environments. Following the dance class, CD62L expression in lymphocytes decreased (51.42%), while there was a negative correlation between the intensity of the exercise and CD62L expression (r = -0.73; p = 0.01). Lymphocytes were less responsive to stimuli after a single bout of street dancing, indicating transient immunosuppression
AOX degradation of the pulp and paper industry bleaching wastewater using nZVI in two different agitation processes
The pulp and paper industry has been researching different treatments for the degradation of adsorbable organohalogens (AOX). In this work, two agitation processes (mechanical and ultrasound) were analyzed in the AOX degradation of the bleaching wastewater using nano zero valent iron (nZVI). The work used different variables for the AOX removal process, such as pH, time, nZVI, and hydrogen peroxide (H2O2) concentration. Results show an increase in AOX degradation when a higher nZVI concentration is used. The optimal combination of variables for the treatment with mechanical agitation was found in the ratio 2:5 (nZVI : H2O2), degrading 85% of AOX in 60 min, with acid pH. Ultrasound treatment consisted of half process time and less degradation than mechanical agitation treatment. The 2:5 ratio in ultrasound agitation degraded 55% of AOX within 30 min at the end of the process. Both methods of the homogenization process of zero valent iron nanoparticles in the bleaching wastewater of the paper and cellulose industry are efficient. However, the mechanical stirring process has a more significant potential for AOX degradation. The variables (pH, concentration of nZVI and H2O2 and duration of the process) used in the bleaching wastewater treatment process must be considered for future implementation in the pulp and paper industry.publishe
Career resources among higher education students: a mixed-methods study
Las universidades han sido cuestionadas por su contribución al desarrollo de la empleabilidad
de su alumnado. Este tema es particularmente relevante por la incertidumbre que genera
el mercado laboral, especialmente para la juventud, acentuado por la crisis pandémica de
la Covid-19. Con este punto de partida, se realiza una conceptualización de los recursos de
carrera, configurados por un conjunto de factores que inciden en el desarrollo profesional:
los recursos relativos al capital humano, al capital social, psicológicos y los relacionadoscon la identidad. Seguidamente, se establece como propósito de la investigación explorar
el desarrollo de los recursos de carrera y analizar la perspectiva del alumnado universitario
sobre la contribución de sus estudios para conseguir sus metas profesionales. Para ello se
realizó un análisis mixto explicativo secuencial. Se aplicó el cuestionario de recursos de
carrera a 339 estudiantes de educación superior de una universidad pública española y se
realizaron 18 entrevistas. Los resultados obtenidos muestran que los recursos de carrera son
generalmente trabajados y desarrollados en los estudios universitarios de grado. Asimismo,
se han identificado algunas dimensiones que presentan una mayor debilidad, como el
conocimiento de las oportunidades de futuro en su entorno próximo; y la conexión entre
sus características individuales y las experiencias educativas en el desarrollo de los recursos
de carrera. Por tanto, este trabajo contribuye a identificar aquellos recursos profesionales
específicos que necesitan una mayor atención en la enseñanza universitaria y supone un
punto de partida para continuar la investigación en otras instituciones de educación superior
en intervenciones, en términos curriculares, pedagógicos y de orientación para la carrera y
poder ampliar el conocimiento en este sentido.Increased attention has been paid to the way Higher Education institutions contribute to
the development of graduates’ employability. Such issue is particularly relevant in the light
of the current uncertainty experienced in the labour market, particularly among younger
people, that was recently exacerbated by the Covid-19 pandemic crisis. Building on the
career resources framework, which integrates a set of resources that are expected to predict
career success, including human capital resources, social capital, psychological resources
and career identity resources, this study aims to explore the development of student’s
career resources over their graduation courses and students’ perceptions about the
contribution of their higher education degree for career success. For this purpose, a mixedmethod explanatory sequential design was conducted. The career resources questionnaire
was applied to 339 Spanish higher education students from a public university, and then
18 interviews were conducted. The results obtained allow us to conclude that career
resources are generally malleable and developed throughout higher education studies. It is
also possible to identify dimensions where students present more fragilities, namely those
related to the exploration of knowledge related to future professional opportunities in their
surrounding environment, and to establish some relation between individual characteristics
and educational experiences and the development of career resources. Thus, this research
adds knowledge to the identification of specific career resources that need more attention
in higher education programs. Implications from this study are discussed, taking its potential
to higher education institutions in interventions, in terms of curriculum, pedagogical and/or
career counselling actions
Career Resources among Higher Education Students: a ixed-method Study
[Resumen] Las universidades han sido cuestionadas por su contribución al desarrollo de la empleabilidad de su alumnado. Este tema es particularmente relevante por la incertidumbre que genera el mercado laboral, especialmente para la juventud, acentuado por la crisis pandémica de la Covid-19. Con este punto de partida, se realiza una conceptualización de los recursos de carrera, configurados por un conjunto de factores que inciden en el desarrollo profesional: los recursos relativos al capital humano, al capital social, psicológicos y los relacionados con la identidad. Seguidamente, se establece como propósito de la investigación explorar el desarrollo de los recursos de carrera y analizar la perspectiva del alumnado universitario sobre la contribución de sus estudios para conseguir sus metas profesionales. Para ello se realizó un análisis mixto exploratorio secuencial. Se aplicó el cuestionario de recursos de carrera a 339 estudiantes de educación superior de una universidad pública española y se realizaron 18 entrevistas. Los resultados obtenidos muestran que los recursos de carrera son generalmente trabajados y desarrollados en los estudios universitarios de grado. Asimismo, se han identificado algunas dimensiones que presentan una mayor debilidad, como el conocimiento de las oportunidades de futuro en su entorno próximo; y la conexión entre sus características individuales y las experiencias educativas en el desarrollo de los recursos de carrera. Por tanto, este trabajo contribuye a identificar aquellos recursos profesionales específicos que necesitan una mayor atención en la enseñanza universitaria y supone un punto de partida para continuar la investigación en otras instituciones de educación superior en intervenciones, en términos curriculares, pedagógicos y de orientación para la carrera y poder ampliar el conocimiento en este sentido.[Abstract] Increased attention has been paid to the way Higher Education institutions contribute to the development of graduates’ employability. Such issue is particularly relevant in the light of the current uncertainty experienced in the labour market, particularly among younger people, that was recently exacerbated by the Covid-19 pandemic crisis. Building on the career resources framework, which integrates a set of resources that are expected to predict career success, including human capital resources, social capital, psychological resources and career identity resources, this study aims to explore the development of student’s career resources over their graduation courses and students’ perceptions about the contribution of their higher education degree for career success. For this purpose, a mixed-method explanatory sequential design was conducted. The career resources questionnaire was applied to 339 Spanish higher education students from a public university, and then 18 interviews were conducted. The results obtained allow us to conclude that career resources are generally malleable and developed throughout higher education studies. It is also possible to identify dimensions where students present more fragilities, namely those related to the exploration of knowledge related to future professional opportunities in their surrounding environment, and to establish some relation between individual characteristics and educational experiences and the development of career resources. Thus, this research adds knowledge to the identification of specific career resources that need more attention in higher education programs. Implications from this study are discussed, taking its potential to higher education institutions in interventions, in terms of curriculum, pedagogical and/or career counselling actions.Fundación Portuguesa para la Ciencia y la Tecnología; PTDC/CED-EDG/0122/2020Fundación Portuguesa para la Ciencia y la Tecnología; UIDB/01661/2020Fundación Portuguesa para la Ciencia y la Tecnología; UIDP/01661/202
Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers
Herein, we investigated the effects of a ballet class on the kinetic profiles of creatine kinase (CK) and lactate dehydrogenase (LDH) activities, cytokines, complement component 3 (C3), and the concentrations of immunoglobulin (Ig), IgA and IgM, in ballerinas. We also verified neutrophil death and ROS release. Blood samples were taken from 13 dancers before, immediately after, and 18 hours after a ballet class. The ballet class increased the plasma activities of CK-total (2.0-fold) immediately after class, while the activities of CK-cardiac muscle (1.0-fold) and LDH (3.0-fold) were observed to increase 18 hours after the class. Levels of the TNF-α, IL-1β, IgG, and IgA were not affected under the study conditions. The exercise was found to induce neutrophil apoptosis (6.0-fold) 18 hours after the ballet class. Additionally, immediately after the ballet class, the neutrophils from the ballerinas were found to be less responsive to PMA stimulus. Conclusion. Ballet class was found to result in inflammation in dancers. The inflammation caused by the ballet class remained for 18 hours after the exercise. These findings are important in preventing the development of chronic lesions that are commonly observed in dancers, such as those with arthritis and synovitis
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