814 research outputs found
Covering classes and 1-tilting cotorsion pairs over commutative rings
We are interested in characterising the commutative rings for which a 1-tilting cotorsion pair provides for covers, that is when the class A is a covering class. We use HrbekĆĄfs bijective correspondence between the 1-tilting cotorsion pairs over a commutative ring R and the faithful finitely generated Gabriel topologies on R. Moreover, we use results of Bazzoni-Positselski, in particular a generalisation of Matlis equivalence and their characterisation of covering classes for 1-tilting cotorsion pairs arising from flat injective ring epimorphisms. Explicitly, if is the Gabriel topology associated to the 1-tilting cotorsion pair, and R is the ring of quotients with respect to, we show that if A is covering, then G is a perfect localisation (in StenstromĆĄfs sense [B. Stenstrom, Rings of Quotients, Springer, New York, 1975]) and the localisation R has projective dimension at most one as an R-module. Moreover, we show that is covering if and only if both the localisation RG and the quotient rings R/J are perfect rings for every J â. Rings satisfying the latter two conditions are called G-almost perfect
Switchable resolution in soft x-ray tomography of single cells.
The diversity of living cells, in both size and internal complexity, calls for imaging methods with adaptable spatial resolution. Soft x-ray tomography (SXT) is a three-dimensional imaging technique ideally suited to visualizing and quantifying the internal organization of single cells of varying sizes in a near-native state. The achievable resolution of the soft x-ray microscope is largely determined by the objective lens, but switching between objectives is extremely time-consuming and typically undertaken only during microscope maintenance procedures. Since the resolution of the optic is inversely proportional to the depth of focus, an optic capable of imaging the thickest cells is routinely selected. This unnecessarily limits the achievable resolution in smaller cells and eliminates the ability to obtain high-resolution images of regions of interest in larger cells. Here, we describe developments to overcome this shortfall and allow selection of microscope optics best suited to the specimen characteristics and data requirements. We demonstrate that switchable objective capability advances the flexibility of SXT to enable imaging cells ranging in size from bacteria to yeast and mammalian cells without physically modifying the microscope, and we demonstrate the use of this technology to image the same specimen with both optics
Conception de signaux de référence pour l'évaluation de la qualité perçue des codecs de la parole et du son
Ce travail vise à fournir les signaux de référence représentatifs des nouvelles techniques de codage pour l'évaluation subjective de la qualité de parole codée. La démarche adoptée consiste à caractériser d'un point de vue perceptif les dégradations apportées par les nouveaux codecs, puis à les relier aux techniques de codage afin de pouvoir les recréer artificiellement. La MDS (Multidimensional Scaling ou analyse multidimensionnelle des proximités) non métrique pondérée est utilisée pour générer l'espace perceptif de dégradations de codecs wideband. L'analyse révÚle un espace perceptif à quatre dimensions interprétable vis-à -vis des techniques de codage
Two Energy Scales and two Quasiparticle Dynamics in the Superconducting State of Underdoped Cuprates
The superconducting state of underdoped cuprates is often described in terms
of a single energy-scale, associated with the maximum of the (d-wave) gap.
Here, we report on electronic Raman scattering results, which show that the gap
function in the underdoped regime is characterized by two energy scales,
depending on doping in opposite manners. Their ratios to the maximum critical
temperature are found to be universal in cuprates. Our experimental results
also reveal two different quasiparticle dynamics in the underdoped
superconducting state, associated with two regions of momentum space: nodal
regions near the zeros of the superconducting gap and antinodal regions. While
antinodal quasiparticles quickly loose coherence as doping is reduced, coherent
nodal quasiparticles persist down to low doping levels. A theoretical analysis
using a new sum-rule allows us to relate the low-frequency-dependence of the
Raman response to the temperature-dependence of the superfluid density, both
controlled by nodal excitations.Comment: 16 pages, 5 figure
Human arachnoid granulations Part I: a technique for quantifying area and distribution on the superior surface of the cerebral cortex
<p>Abstract</p> <p>Background</p> <p>The arachnoid granulations (AGs) are herniations of the arachnoid membrane into the dural venous sinuses on the surface of the brain. Previous morphological studies of AGs have been limited in scope and only one has mentioned surface area measurements. The purpose of this study was to investigate the topographic distribution of AGs on the superior surface of the cerebral cortex.</p> <p>Methods</p> <p><it>En face </it>images were taken of the superior surface of 35 formalin-fixed human brains. AGs were manually identified using Adobe Photoshop, with a pixel location containing an AG defined as 'positive'. A set of 25 standard fiducial points was marked on each hemisphere for a total of 50 points on each image. The points were connected on each hemisphere to create a segmented image. A standard template was created for each hemisphere by calculating the average position of the 25 fiducial points from all brains. Each segmented image was mapped to the standard template using a linear transformation. A topographic distribution map was produced by calculating the proportion of AG positive images at each pixel in the standard template. The AG surface area was calculated for each hemisphere and for the total brain superior surface. To adjust for different brain sizes, the proportional involvement of AGs was calculated by dividing the AG area by the total area.</p> <p>Results</p> <p>The total brain average surface area of AGs was 78.53 ± 13.13 mm<sup>2 </sup>(n = 35) and average AG proportional involvement was 57.71 à 10<sup>-4 </sup>± 7.65 à 10<sup>-4</sup>. Regression analysis confirmed the reproducibility of AG identification between independent researchers with r<sup>2 </sup>= 0.97. The surface AGs were localized in the parasagittal planes that coincide with the region of the lateral lacunae.</p> <p>Conclusion</p> <p>The data obtained on the spatial distribution and <it>en face </it>surface area of AGs will be used in an <it>in vitro </it>model of CSF outflow. With an increase in the number of samples, this analysis technique can be used to study the relationship between AG surface area and variables such as age, race and gender.</p
The conserved C-terminus of the PcrA/UvrD helicase interacts directly with RNA polymerase
Copyright: © 2013 Gwynn et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: This work was supported by a Wellcome Trust project grant to MD (Reference: 077368), an ERC starting grant to MD (Acronym: SM-DNA-REPAIR) and a BBSRC project grant to PM, NS and MD (Reference: BB/I003142/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD
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Imaging at high spatial resolution: Soft x-ray microscopy to 15nm
Soft x-ray microscopy has now achieved 15 nm spatial resolution with new zone plates and bending magnet radiation. Combined with elemental sensitivity and flexible sample environment (applied magnetic or electric fields, wet samples, windows, overcoatings) this emerges as a valuable tool for nanoscience and nanotechnology, complimenting common electron and scanning tip microscopies. In this presentation we describe recent advances in spatial resolution, expectations for the near future, and applications to magnetic materials, bio-tomography, etc
Successive opening of the Fermi surface in doped N-leg Hubbard ladders
We study the effect of doping away from half-filling in weakly (but finitely)
interacting N-leg Hubbard ladders using renormalization group and bosonization
techniques. For a small on-site repulsion U, the N-leg Hubbard ladders are
equivalent to a N-band model, where at half-filling the Fermi velocities are
v_{1}=v_{N}<v_{2}=v_{N-1}<... We then obtain a hierarchy of energy-scales,
where the band pairs (j,N+1-j) are successively frozen out. The low-energy
Hamiltonian is then the sum of N/2 (or (N-1)/2 for N odd) two-leg ladder
Hamiltonians without gapless excitations (plus a single chain for N odd with
one gapless spin mode), similar to the N-leg Heisenberg spin-ladders. The
energy-scales lead to a hierarchy of gaps. Upon doping away from half-filling,
the holes enter first the band(s) with the smallest gap: For odd N, the holes
enter first the nonbonding band (N+1)/2 and the phase is a Luttinger liquid,
while for even N, the holes enter first the band pair (N/2,N/2+1) and the phase
is a Luther-Emery liquid, similar to numerical treatments of the t-J model,
i.e., at and close to half-filling, the phases of the Hubbard ladders for small
and large U are the same. For increasing doping, hole-pairs subsequently enter
at critical dopings the other band pairs (j,N+1-j) (accompanied by a diverging
compressibility): The Fermi surface is successively opened by doping, starting
near the wave vector (pi/2,pi/2). Explicit calculations are given for the cases
N=3,4.Comment: 10 pages, 4 figures, to be published in Phys. Rev.
A search for low-mass WIMPs with EDELWEISS-II heat-and-ionization detectors
We report on a search for low-energy (E < 20 keV) WIMP-induced nuclear
recoils using data collected in 2009 - 2010 by EDELWEISS from four germanium
detectors equipped with thermal sensors and an electrode design (ID) which
allows to efficiently reject several sources of background. The data indicate
no evidence for an exponential distribution of low-energy nuclear recoils that
could be attributed to WIMP elastic scattering after an exposure of 113 kg.d.
For WIMPs of mass 10 GeV, the observation of one event in the WIMP search
region results in a 90% CL limit of 1.0x10^-5 pb on the spin-independent
WIMP-nucleon scattering cross-section, which constrains the parameter space
associated with the findings reported by the CoGeNT, DAMA and CRESST
experiments.Comment: PRD rapid communication accepte
Observation of periodic variable stars towards the galactic spiral arms by EROS II
We present the results of a massive variability search based on a photometric
survey of a six square degree region along the Galactic plane at (, ) and (, ). This
survey was performed in the framework of the EROS II (Exp\'erience de Recherche
d'Objets Sombres) microlensing program. The variable stars were found among
1,913,576 stars that were monitored between April and June 1998 in two
passbands, with an average of 60 measurements. A new period-search technique is
proposed which makes use of a statistical variable that characterizes the
overall regularity of the flux versus phase diagram. This method is well suited
when the photometric data are unevenly distributed in time, as is our case.
1,362 objects whose luminosity varies were selected. Among them we identified 9
Cepheids, 19 RR Lyrae, 34 Miras, 176 eclipsing binaries and 266 Semi-Regular
stars. Most of them are newly identified objects. The cross-identification with
known catalogues has been performed. The mean distance of the RR Lyrae is
estimated to be kpc undergoing an average absorption of
magnitudes. This distance is in good agreement with the one
of disc stars which contribute to the microlensing source star population.Our
catalogue and light curves are available electronically from the CDS,
Strasbourg and from our Web site http://eros.in2p3.fr.Comment: 15 pages, 11 figures, accepted in A&A (april 2002
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