Electrostatic Waves in Magnetized Electron-Positron Plasmas

The behavior of arbitrary amplitude linear and nonlinear electrostatic waves that propagate in a magnetized four component, two-temperature, electron-positron plasma is presented. The characteristics of the dispersive properties of the associated linear modes using both fluid and kinetic theory are examined. The fluid theory analysis of the electrostatic linear waves shows the existence of electron acoustic, upper hybrid, electron plasma and electron cyclotron branches. A kinetic theory analysis is then used to study the acoustic mode, in particular the effect of Landau damping, which for the parameter regime considered is due to the cooler species. Consequently, it is found that a large enough drift velocity is required to produce wave growth. Nonlinear electrostatic solitary waves (ESWs), similar to those found in the broadband electrostatic noise observed in various regions of the earth’s magnetosphere is further investigated. A set of nonlinear differential equations for the ESWs, which propagate obliquely to an external magnetic field is derived and numerically solved. The effect of various plasma parameters on the waves is explored and shows that as the electric driving force is increased, the electric field structure evolves from a sinusoidal wave to a spiky bipolar form. The results are relevant to both astrophysical environments and related laser-induced laboratory experiments

Linear and nonlinear fluctuations in electron-positron plasmas.

Thesis (Ph.D.)-University of KwaZulu-Natal, Westville, 2009.The behaviour of both small amplitude and arbitrary amplitude nonlinear electrostatic fluctuations are studied in electron-positron plasmas. The propagation characteristics of associated linear modes are also examined for selected plasma models. In the case of the four component, two-temperature, electron-positron plasma, three particular features are investigated. The first investigates existence conditions of the range of possible electrostatic linear waves that can propagate in a two-temperature electron-positron plasma, the study being particularly relevant to both astrophysical situations and laser induced fusion experiments. The second includes the development and investigation of the mKdV-ZK equation governing the three dimensional propagation of solitary waves in a magnetized plasma. The third application is the investigation of nonlinear electrostatic solitary waves structures, similar to those found in the broadband electrostatic noise observed in various regions of the earth’s magnetosphere. The study ends by considering relativistic effects on solitary waves in an electron-positron plasma

Performance analysis of grid-tied photovoltaic system under varying weather condition and load

Model and simulation of the impact of the distribution grid-tied photovoltaic (PV) system feeding a variable load with its control system have been investigated in this study. Incremental Conductance (IncCond) algorithm based on maximum power point tracking (MPPT) was implemented for the PV system to extract maximum power under different weather conditions when solar irradiation varies between 250W/m2 and 1000W/m2. The proposed system is modelled and simulated with MATLAB/Simulink tools. Under different weather conditions, the dynamic performance of the PV system is evaluated. The results obtained show the efficacy of the proposed MPPT method in response to rapid daytime weather variations. The results also show that the surplus power generated is injected into the grid when the injected power from the PV system is higher than the load demand; otherwise, the grid supplies the load

Falls self-efficacy and falls incidence in community-dwelling older people: the mediating role of coping

Background: A cognitive behavioural model predicts that coping responses mediate the relationship between falls related psychological concerns and falls incidence, in community-dwelling older people. If empirical support could be found for this pathway then interventions could be developed to reduce falls risk by targeting coping strategies. Therefore, this study aimed to begin the process of testing whether coping responses mediate the association between falls self-efficacy (a principal element of falls related psychological concerns) and falls incidence, in community-dwelling older people. Method: In a cross-sectional design, 160 community–dwelling older people (31 male, 129 female; mean age 83.47 years) completed the Falls Efficacy Scale–International, the Revised-Ways of Coping Questionnaire, the Turning to Religion subscale of the COPE, and a falls questionnaire. Data were analysed via mediation analysis using a bootstrapping approach. Results: Lower falls self-efficacy was associated with higher falls incidence, and more self-controlling coping was found to be a partial mediator of this association, with a confidence interval for the indirect effect of (.003, .021) and an effect size of κ2 = .035. The association was not mediated by the other measured coping responses; namely, turning to religion, distancing, seeking social support, accepting responsibility, escape-avoidance, planful problem-solving and positive reappraisal. Conclusions: Self-controlling coping may mediate the association between falls self-efficacy and falling. If longitudinal studies confirm this finding then coping could be targeted in interventions to reduce falls

Partially-constrained sex allocation and the indirect effects of assisted reproductive technologies on the human sex ratio

Infertility affects around 15% of human couples and in many countries approximately 1–4% of babies are born following Assisted Reproductive Technologies (ART). Several ART techniques are used and these differentially affect the sex ratio of offspring successfully produced. These direct effects on sex ratio also have the potential to influence, indirectly, the sex ratios of offspring born to untreated couples. This is of concern because human sex ratio bias may adversely affect public health. Here the extent of indirect effects of ART that could operate, via Fisherian frequency-dependent natural selection, on the progeny sex ratio of unassisted members of a population is heuristically modelled. Given the degrees to which ART techniques bias sex ratios directly, it is predicted that well over 20% of couples would have to reproduce via ART for there to be any discernible effect on the sex ratios produced, in response, by the remainder of the population. This value is greater than the estimated prevalence of infertility problems among human couples. It is concluded that providing ART to couples with fertility problems does not currently generate significant ethical issues or public health concern in terms of indirect effects on the offspring sex ratios of untreated couples

Environmental signal shredding on sandy coastlines

How storm events contribute to long-term shoreline change over decades to centuries remains an open question in coastal research. Sand and gravel coasts exhibit remarkable resilience to event-driven disturbances, and, in settings where sea level is rising, shorelines retain almost no detailed information about their own past positions. Here, we use a high-frequency, multi-decadal observational record of shoreline position to demonstrate quantitative indications of morphodynamic turbulence – “signal shredding” – in a sandy beach system. We find that, much as in other dynamic sedimentary systems, processes of sediment transport that affect shoreline position at relatively short timescales may obscure or erase evidence of external forcing. This suggests that the physical effects of annual (or intra-annual) forcing events, including major storms, may convey less about the dynamics of long-term shoreline change – and vice versa – than coastal researchers might wish

Cleaning the Cellular Factory:Deletion of McrA in Aspergillus oryzae NSAR1 and the generation of a novel kojic acid deficient strain for cleaner heterologous production of secondary metabolites

The use of filamentous fungi as cellular factories, where natural product pathways can be refactored and expressed in a host strain, continues to aid the field of natural product discovery. Much work has been done to develop host strains which are genetically tractable, and for which there are multiple selectable markers and controllable expression systems. To fully exploit these strains, it is beneficial to understand their natural metabolic capabilities, as such knowledge can rule out host metabolites from analysis of transgenic lines and highlight any potential interplay between endogenous and exogenous pathways. Additionally, once identified, the deletion of secondary metabolite pathways from host strains can simplify the detection and purification of heterologous compounds. To this end, secondary metabolite production in Aspergillus oryzae strain NSAR1 has been investigated via the deletion of the newly discovered negative regulator of secondary metabolism, mcrA (multicluster regulator A). In all ascomycetes previously studied mcrA deletion led to an increase in secondary metabolite production. Surprisingly, the only detectable phenotypic change in NSAR1 was a doubling in the yields of kojic acid, with no novel secondary metabolites produced. This supports the previous claim that secondary metabolite production has been repressed in A. oryzae and demonstrates that such repression is not McrA-mediated. Strain NSAR1 was then modified by employing CRISPR-Cas9 technology to disrupt the production of kojic acid, generating the novel strain NSARΔK, which combines the various beneficial traits of NSAR1 with a uniquely clean secondary metabolite background

Transitions in modes of coastal adaptation: addressing blight, engagement and sustainability

Coastal defences have long provided protection from erosion and flooding to cities, towns and villages. In many parts of the world, continued defence is being questioned due to both environmental, sustainability and economic considerations. This is exemplified in England and Wales, where strategic Shoreline Management Plans envisage realignment of many protected coasts, often with low population densities, over the coming decades. The policy transition from protection to realignment is often resisted by affected communities and can have high political costs. Whilst some preparations for such transitions have been made, the communities affected are often not fully aware of the implications of policy change, and this brings the potential for blight. In this paper, we investigate the challenges of implementing transitions in coastal policy within England and Wales. The analysis is based on data obtained from three workshops held in 2019 that were attended by council members, engineers, planners, scientists and other relevant professionals. Five conditions are found to promote contention: (i) policy actors with competing priorities and different decision making time frames (immediate to decadal to a century); (ii) divergence between regulations and ad hoc political decisions (e.g. in relation to the demand for new housing); (iii) limited or non-existent funding to support policy transition; (iv) community expectation that protection is forever; and (v) a disconnection between people and ongoing coastal change. Our research indicates that transitions can be better supported through: (1) integrated multi-scalar preparedness for coastal change; (2) an accessible evidence base and future vision to nurture political confidence in adaptation; and (3) defined, time-bound and accessible diverse funding streams to achieve transitions. Critically, these generic actions need to be embedded within the local political and planning system to facilitate transition to more sustainable coasts and their communities

Emerging communities of child-healthcare practice in the management of long-term conditions such as chronic kidney disease: Qualitative study of parents' accounts

Background: Parents of children and young people with long-term conditions who need to deliver clinical care to their child at home with remote support from hospital-based professionals, often search the internet for care-giving information. However, there is little evidence that the information available online was developed and evaluated with parents or that it acknowledges the communities of practice that exist as parents and healthcare professionals share responsibility for condition management. Methods. The data reported here are part of a wider study that developed and tested a condition-specific, online parent information and support application with children and young people with chronic-kidney disease, parents and professionals. Semi-structured interviews were conducted with 19 fathers and 24 mothers who had recently tested the novel application. Data were analysed using Framework Analysis and the Communities of Practice concept. Results: Evolving communities of child-healthcare practice were identified comprising three components and several sub components: (1) Experiencing (parents making sense of clinical tasks) through Normalising care, Normalising illness, Acceptance & action, Gaining strength from the affected child and Building relationships to formalise a routine; (2) Doing (Parents executing tasks according to their individual skills) illustrated by Developing coping strategies, Importance of parents' efficacy of care and Fear of the child's health failing; and (3) Belonging/Becoming (Parents defining task and group members' worth and creating a personal identity within the community) consisting of Information sharing, Negotiation with health professionals and Achieving expertise in care. Parents also recalled factors affecting the development of their respective communities of healthcare practice; these included Service transition, Poor parent social life, Psycho-social affects, Family chronic illness, Difficulty in learning new procedures, Shielding and avoidance, and Language and cultural barriers. Health care professionals will benefit from using the communities of child-healthcare practice model when they support parents of children with chronic kidney disease. Conclusions: Understanding some of the factors that may influence the development of communities of child-healthcare practice will help professionals to tailor information and support for parents learning to manage their child's healthcare. Our results are potentially transferrable to professionals managing the care of children and young people with other long-term conditions. © 2014 Carolan et al.; licensee BioMed Central Ltd

A simulation study comparing aberration detection algorithms for syndromic surveillance

BACKGROUND: The usefulness of syndromic surveillance for early outbreak detection depends in part on effective statistical aberration detection. However, few published studies have compared different detection algorithms on identical data. In the largest simulation study conducted to date, we compared the performance of six aberration detection algorithms on simulated outbreaks superimposed on authentic syndromic surveillance data. METHODS: We compared three control-chart-based statistics, two exponential weighted moving averages, and a generalized linear model. We simulated 310 unique outbreak signals, and added these to actual daily counts of four syndromes monitored by Public Health – Seattle and King County's syndromic surveillance system. We compared the sensitivity of the six algorithms at detecting these simulated outbreaks at a fixed alert rate of 0.01. RESULTS: Stratified by baseline or by outbreak distribution, duration, or size, the generalized linear model was more sensitive than the other algorithms and detected 54% (95% CI = 52%–56%) of the simulated epidemics when run at an alert rate of 0.01. However, all of the algorithms had poor sensitivity, particularly for outbreaks that did not begin with a surge of cases. CONCLUSION: When tested on county-level data aggregated across age groups, these algorithms often did not perform well in detecting signals other than large, rapid increases in case counts relative to baseline levels